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Serum circular RNAs act as blood-based biomarkers for hypertrophic obstructive cardiomyopathy.
Sonnenschein K, Wilczek AL, de Gonzalo-Calvo D, Pfanne A, Derda AA, Zwadlo C, Bavendiek U, Bauersachs J, Fiedler J, Thum T. Sonnenschein K, et al. Sci Rep. 2019 Dec 30;9(1):20350. doi: 10.1038/s41598-019-56617-2. Sci Rep. 2019. PMID: 31889077 Free PMC article.
Abundancy of circRNAs was then correlated to relevant clinical parameters. Serum expression levels of circRNAs DNAJC6, TMEM56 and MBOAT2 were downregulated in patients with HCM. The inverse association between circRNA levels and HCM remained unchanged even after adjusting …
Abundancy of circRNAs was then correlated to relevant clinical parameters. Serum expression levels of circRNAs DNAJC6, TMEM56 and MBO …
Identification and Validation of a Prognostic Risk-Scoring Model Based on Ferroptosis-Associated Cluster in Acute Myeloid Leukemia.
Wang J, Zhuo Z, Wang Y, Yang S, Chen J, Wang Y, Geng S, Li M, Du X, Lai P, Weng J. Wang J, et al. Front Cell Dev Biol. 2022 Jan 21;9:800267. doi: 10.3389/fcell.2021.800267. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35127715 Free PMC article.
Results: Eighteen signature genes, including ZSCAN4, ASTN1, CCL23, DLL3, EFNB3, FAM155B, FOXL1, HMX2, HRASLS, LGALS1, LHX6, MXRA5, PCDHB12, PRINS, TMEM56, TWIST1, ZFPM2, and ZNF560, were developed to construct a prognostic risk-scoring model. ...Further analyses demonstrat …
Results: Eighteen signature genes, including ZSCAN4, ASTN1, CCL23, DLL3, EFNB3, FAM155B, FOXL1, HMX2, HRASLS, LGALS1, LHX6, MXRA5, PCDHB12, …
Gene expression signatures of coronary heart disease.
Joehanes R, Ying S, Huan T, Johnson AD, Raghavachari N, Wang R, Liu P, Woodhouse KA, Sen SK, Tanriverdi K, Courchesne P, Freedman JE, O'Donnell CJ, Levy D, Munson PJ. Joehanes R, et al. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1418-26. doi: 10.1161/ATVBAHA.112.301169. Epub 2013 Mar 28. Arterioscler Thromb Vasc Biol. 2013. PMID: 23539218 Free PMC article.
APPROACH AND RESULTS: A total of 35 genes were differentially expressed in cases with CHD versus controls at false discovery rate<0.5, including GZMB, TMEM56, and GUK1. Cluster analysis revealed 3 gene clusters associated with CHD, 2 linked to increased erythrocyte prod …
APPROACH AND RESULTS: A total of 35 genes were differentially expressed in cases with CHD versus controls at false discovery rate<0.5, in …
Quantitative analysis of noncoding RNA from paired fresh and formalin-fixed paraffin-embedded brain tissues.
Lv Y, Li S, Li Z, Tao R, Shao Y, Chen Y. Lv Y, et al. Int J Legal Med. 2020 May;134(3):873-884. doi: 10.1007/s00414-019-02210-1. Epub 2019 Dec 1. Int J Legal Med. 2020. PMID: 31788707
., ACTB mRNA and MALAT1 lncRNA) exhibited high consistency of quantification in paired fresh/FFPE samples. In particular, circRNAs (XPO1, HIPK3, and TMEM56) presented relatively consistent and stable expression profiles in FFPE tissues compared with their corresponding lin …
., ACTB mRNA and MALAT1 lncRNA) exhibited high consistency of quantification in paired fresh/FFPE samples. In particular, circRNAs (XPO1, HI …
Gene expression patterns in livers of Hispanic patients infected with hepatitis C virus.
Hevezi PA, Tom E, Wilson K, Lambert P, Gutierrez-Reyes G, Kershenobich D, Zlotnik A. Hevezi PA, et al. Autoimmunity. 2011 Nov;44(7):532-42. doi: 10.3109/08916934.2011.592881. Epub 2011 Aug 24. Autoimmunity. 2011. PMID: 21864061
The genes induced by HCV infection showed large expression changes, whereas the genes induced by the IFN-alpha combination therapy were relatively few (including MX2, ORMDL3, GPAM, KOPX18, TMEM56, and HBP1) and they reflected relatively small expression changes. ...
The genes induced by HCV infection showed large expression changes, whereas the genes induced by the IFN-alpha combination therapy were rela …
Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study.
Yang HC, Liang YJ, Chen JW, Chiang KM, Chung CM, Ho HY, Ting CT, Lin TH, Sheu SH, Tsai WC, Chen JH, Leu HB, Yin WH, Chiu TY, Chern CL, Lin SJ, Tomlinson B, Guo Y, Sham PC, Cherny SS, Lam TH, Thomas GN, Pan WH. Yang HC, et al. PLoS One. 2012;7(3):e32907. doi: 10.1371/journal.pone.0032907. Epub 2012 Mar 29. PLoS One. 2012. PMID: 22479346 Free PMC article.
SFMBT1, which encodes the scm-like with four MBT domains protein 1, is a novel hypertension gene. GRB14, TMEM56 and KIAA1797 exhibited highly significant differential allelic and expressed distributions between hypertensive patients and normotensive controls. GRB14 was als …
SFMBT1, which encodes the scm-like with four MBT domains protein 1, is a novel hypertension gene. GRB14, TMEM56 and KIAA1797 exhibite …