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Items: 1 to 50 of 139

1.

RNA sequencing profiles and diagnostic signatures linked with response to ramucirumab in gastric cancer.

Sorokin M, Poddubskaya E, Baranova M, Glusker A, Kogoniya L, Markarova E, Allina D, Suntsova M, Tkachev V, Garazha A, Sekacheva M, Buzdin A.

Cold Spring Harb Mol Case Stud. 2020 Feb 14. pii: mcs.a004945. doi: 10.1101/mcs.a004945. [Epub ahead of print]

2.

Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer.

Zolotovskaia MA, Tkachev VS, Seryakov AP, Kuzmin DV, Kamashev DE, Sorokin MI, Roumiantsev SA, Buzdin AA.

Cancers (Basel). 2020 Jan 22;12(2). pii: E271. doi: 10.3390/cancers12020271.

3.

Flexible Data Trimming Improves Performance of Global Machine Learning Methods in Omics-Based Personalized Oncology.

Tkachev V, Sorokin M, Borisov C, Garazha A, Buzdin A, Borisov N.

Int J Mol Sci. 2020 Jan 22;21(3). pii: E713. doi: 10.3390/ijms21030713.

4.

Visible to near-IR molecular switches based on photochromic indoline spiropyrans with a conjugated cationic fragment.

Pugachev AD, Ozhogin IV, Lukyanova MB, Lukyanov BS, Rostovtseva IA, Dorogan IV, Makarova NI, Tkachev VV, Metelitsa AV, Aldoshin SM.

Spectrochim Acta A Mol Biomol Spectrosc. 2020 Apr 5;230:118041. doi: 10.1016/j.saa.2020.118041. Epub 2020 Jan 7.

PMID:
31955116
5.

The Effect of Nitroxyalkyl Succinimides on Activity of Cyclic Guanosine Monophosphate Phosphodiesterase.

Tat'yanenko LV, Dobrokhotova OV, Fadeev MA, Eremeev AB, Utyonishev AN, Tkachev VV, Goryachev NS, Kotelnikov AI, Fedorov BS.

Bull Exp Biol Med. 2020 Jan;168(3):330-333. doi: 10.1007/s10517-020-04702-2. Epub 2020 Jan 15.

PMID:
31940127
6.

[ARTERIAL HYPERTENSION AMONG WORKERS OF A URANIUM PROCESSING ENTERPRISE OF THE REPUBLIC OF KAZAKHSTAN: PREVALENCE, RELATIVE RISKS AND PREDICTORS OF THE DEVELOPMENT].

Bekenova F, Tkachev V, Baidurin S, Blyalova D, Akhmetzhanova S.

Georgian Med News. 2019 Sep;(294):182-187. Russian.

PMID:
31687973
7.

Oncobox Method for Scoring Efficiencies of Anticancer Drugs Based on Gene Expression Data.

Tkachev V, Sorokin M, Garazha A, Borisov N, Buzdin A.

Methods Mol Biol. 2020;2063:235-255. doi: 10.1007/978-1-0716-0138-9_17.

PMID:
31667774
8.

Retroelement-Linked H3K4me1 Histone Tags Uncover Regulatory Evolution Trends of Gene Enhancers and Feature Quickly Evolving Molecular Processes in Human Physiology.

Nikitin D, Kolosov N, Murzina A, Pats K, Zamyatin A, Tkachev V, Sorokin M, Kopylov P, Buzdin A.

Cells. 2019 Oct 8;8(10). pii: E1219. doi: 10.3390/cells8101219.

9.

Exact solution of three-level model of excited state electron transfer symmetry breaking in quadrupolar molecules.

Ivanov AI, Tkachev VG.

J Chem Phys. 2019 Sep 28;151(12):124309. doi: 10.1063/1.5116015.

PMID:
31575174
10.

H3K4me3, H3K9ac, H3K27ac, H3K27me3 and H3K9me3 Histone Tags Suggest Distinct Regulatory Evolution of Open and Condensed Chromatin Landmarks.

Igolkina AA, Zinkevich A, Karandasheva KO, Popov AA, Selifanova MV, Nikolaeva D, Tkachev V, Penzar D, Nikitin DM, Buzdin A.

Cells. 2019 Sep 5;8(9). pii: E1034. doi: 10.3390/cells8091034.

11.

The formation of human populations in South and Central Asia.

Narasimhan VM, Patterson N, Moorjani P, Rohland N, Bernardos R, Mallick S, Lazaridis I, Nakatsuka N, Olalde I, Lipson M, Kim AM, Olivieri LM, Coppa A, Vidale M, Mallory J, Moiseyev V, Kitov E, Monge J, Adamski N, Alex N, Broomandkhoshbacht N, Candilio F, Callan K, Cheronet O, Culleton BJ, Ferry M, Fernandes D, Freilich S, Gamarra B, Gaudio D, Hajdinjak M, Harney É, Harper TK, Keating D, Lawson AM, Mah M, Mandl K, Michel M, Novak M, Oppenheimer J, Rai N, Sirak K, Slon V, Stewardson K, Zalzala F, Zhang Z, Akhatov G, Bagashev AN, Bagnera A, Baitanayev B, Bendezu-Sarmiento J, Bissembaev AA, Bonora GL, Chargynov TT, Chikisheva T, Dashkovskiy PK, Derevianko A, Dobeš M, Douka K, Dubova N, Duisengali MN, Enshin D, Epimakhov A, Fribus AV, Fuller D, Goryachev A, Gromov A, Grushin SP, Hanks B, Judd M, Kazizov E, Khokhlov A, Krygin AP, Kupriyanova E, Kuznetsov P, Luiselli D, Maksudov F, Mamedov AM, Mamirov TB, Meiklejohn C, Merrett DC, Micheli R, Mochalov O, Mustafokulov S, Nayak A, Pettener D, Potts R, Razhev D, Rykun M, Sarno S, Savenkova TM, Sikhymbaeva K, Slepchenko SM, Soltobaev OA, Stepanova N, Svyatko S, Tabaldiev K, Teschler-Nicola M, Tishkin AA, Tkachev VV, Vasilyev S, Velemínský P, Voyakin D, Yermolayeva A, Zahir M, Zubkov VS, Zubova A, Shinde VS, Lalueza-Fox C, Meyer M, Anthony D, Boivin N, Thangaraj K, Kennett DJ, Frachetti M, Pinhasi R, Reich D.

Science. 2019 Sep 6;365(6457). pii: eaat7487. doi: 10.1126/science.aat7487.

12.

Correction: Nikitin, D., et al. Retroelement-Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution. Cells 2019, 8, 130.

Nikitin D, Garazha A, Sorokin M, Penzar D, Tkachev V, Markov A, Gaifullin N, Borger P, Poltorak A, Buzdin A.

Cells. 2019 Aug 5;8(8). pii: E832. doi: 10.3390/cells8080832.

13.

Field-induced single-ion magnet behaviour of a hexacoordinated Co(ii) complex with easy-axis-type magnetic anisotropy.

Tupolova YP, Shcherbakov IN, Popov LD, Lebedev VE, Tkachev VV, Zakharov KV, Vasiliev AN, Korchagin DV, Palii AV, Aldoshin SM.

Dalton Trans. 2019 May 21;48(20):6960-6970. doi: 10.1039/c9dt00770a.

PMID:
31041973
14.

Retroelement-Linked Transcription Factor Binding Patterns Point to Quickly Developing Molecular Pathways in Human Evolution.

Nikitin D, Garazha A, Sorokin M, Penzar D, Tkachev V, Markov A, Gaifullin N, Borger P, Poltorak A, Buzdin A.

Cells. 2019 Feb 6;8(2). pii: E130. doi: 10.3390/cells8020130. Erratum in: Cells. 2019 Aug 05;8(8):.

15.

Shambhala: a platform-agnostic data harmonizer for gene expression data.

Borisov N, Shabalina I, Tkachev V, Sorokin M, Garazha A, Pulin A, Eremin II, Buzdin A.

BMC Bioinformatics. 2019 Feb 6;20(1):66. doi: 10.1186/s12859-019-2641-8.

16.

FLOating-Window Projective Separator (FloWPS): A Data Trimming Tool for Support Vector Machines (SVM) to Improve Robustness of the Classifier.

Tkachev V, Sorokin M, Mescheryakov A, Simonov A, Garazha A, Buzdin A, Muchnik I, Borisov N.

Front Genet. 2019 Jan 15;9:717. doi: 10.3389/fgene.2018.00717. eCollection 2018.

17.

Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation.

Colonna L, Peterson CW, Schell JB, Carlson JM, Tkachev V, Brown M, Yu A, Reddy S, Obenza WM, Nelson V, Polacino PS, Mack H, Hu SL, Zeleski K, Hoffman M, Olvera J, Furlan SN, Zheng H, Taraseviciute A, Hunt DJ, Betz K, Lane JF, Vogel K, Hotchkiss CE, Moats C, Baldessari A, Murnane RD, English C, Astley CA, Wangari S, Agricola B, Ahrens J, Iwayama N, May A, Stensland L, Huang MW, Jerome KR, Kiem HP, Kean LS.

Nat Commun. 2018 Oct 25;9(1):4438. doi: 10.1038/s41467-018-06736-7.

18.

CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates.

Watkins BK, Tkachev V, Furlan SN, Hunt DJ, Betz K, Yu A, Brown M, Poirier N, Zheng HB, Taraseviciute A, Colonna L, Mary C, Blancho G, Soulillou JP, Panoskaltsis-Mortari A, Sharma P, Garcia A, Strobert E, Hamby K, Garrett A, Deane T, Blazar BR, Vanhove B, Kean LS.

J Clin Invest. 2018 Aug 31;128(9):3991-4007. doi: 10.1172/JCI98793. Epub 2018 Aug 13.

19.

Chimeric Antigen Receptor T Cell-Mediated Neurotoxicity in Nonhuman Primates.

Taraseviciute A, Tkachev V, Ponce R, Turtle CJ, Snyder JM, Liggitt HD, Myerson D, Gonzalez-Cuyar L, Baldessari A, English C, Yu A, Zheng H, Furlan SN, Hunt DJ, Hoglund V, Finney O, Brakke H, Blazar BR, Berger C, Riddell SR, Gardner R, Kean LS, Jensen MC.

Cancer Discov. 2018 Jun;8(6):750-763. doi: 10.1158/2159-8290.CD-17-1368. Epub 2018 Mar 21.

20.

Profiling of Human Molecular Pathways Affected by Retrotransposons at the Level of Regulation by Transcription Factor Proteins.

Nikitin D, Penzar D, Garazha A, Sorokin M, Tkachev V, Borisov N, Poltorak A, Prassolov V, Buzdin AA.

Front Immunol. 2018 Jan 30;9:30. doi: 10.3389/fimmu.2018.00030. eCollection 2018.

21.

A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency.

Borisov N, Tkachev V, Suntsova M, Kovalchuk O, Zhavoronkov A, Muchnik I, Buzdin A.

Cell Cycle. 2018;17(4):486-491. doi: 10.1080/15384101.2017.1417706. Epub 2018 Jan 17.

22.

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant.

Tkachev V, Furlan SN, Watkins B, Hunt DJ, Zheng HB, Panoskaltsis-Mortari A, Betz K, Brown M, Schell JB, Zeleski K, Yu A, Kirby I, Cooley S, Miller JS, Blazar BR, Casson D, Bland-Ward P, Kean LS.

Sci Transl Med. 2017 Sep 20;9(408). pii: eaan3085. doi: 10.1126/scitranslmed.aan3085.

23.

Data aggregation at the level of molecular pathways improves stability of experimental transcriptomic and proteomic data.

Borisov N, Suntsova M, Sorokin M, Garazha A, Kovalchuk O, Aliper A, Ilnitskaya E, Lezhnina K, Korzinkin M, Tkachev V, Saenko V, Saenko Y, Sokov DG, Gaifullin NM, Kashintsev K, Shirokorad V, Shabalina I, Zhavoronkov A, Mishra B, Cantor CR, Buzdin A.

Cell Cycle. 2017 Oct 2;16(19):1810-1823. doi: 10.1080/15384101.2017.1361068. Epub 2017 Aug 21.

24.

Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.

Hippen KL, Watkins B, Tkachev V, Lemire AM, Lehnen C, Riddle MJ, Singh K, Panoskaltsis-Mortari A, Vanhove B, Tolar J, Kean LS, Blazar BR.

Transplantation. 2016 Dec;100(12):2630-2639. doi: 10.1097/TP.0000000000001465.

25.

Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells.

Furlan SN, Watkins B, Tkachev V, Cooley S, Panoskaltsis-Mortari A, Betz K, Brown M, Hunt DJ, Schell JB, Zeleski K, Yu A, Giver CR, Waller EK, Miller JS, Blazar BR, Kean LS.

Blood. 2016 Nov 24;128(21):2568-2579. Epub 2016 Oct 6.

26.

The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques.

Zheng HB, Watkins B, Tkachev V, Yu S, Tran D, Furlan S, Zeleski K, Singh K, Hamby K, Hotchkiss C, Lane J, Gumber S, Adams AB, Cendales L, Kirk AD, Kaur A, Blazar BR, Larsen CP, Kean LS.

Am J Transplant. 2017 Mar;17(3):657-670. doi: 10.1111/ajt.14006. Epub 2016 Sep 19.

27.

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.

Saha A, O'Connor RS, Thangavelu G, Lovitch SB, Dandamudi DB, Wilson CB, Vincent BG, Tkachev V, Pawlicki JM, Furlan SN, Kean LS, Aoyama K, Taylor PA, Panoskaltsis-Mortari A, Foncea R, Ranganathan P, Devine SM, Burrill JS, Guo L, Sacristan C, Snyder NW, Blair IA, Milone MC, Dustin ML, Riley JL, Bernlohr DA, Murphy WJ, Fife BT, Munn DH, Miller JS, Serody JS, Freeman GJ, Sharpe AH, Turka LA, Blazar BR.

J Clin Invest. 2016 Jul 1;126(7):2642-60. doi: 10.1172/JCI85796. Epub 2016 Jun 13.

28.

2-Hetaryl-1,3-tropolones based on five-membered nitrogen heterocycles: synthesis, structure and properties.

Sayapin YA, Tupaeva IO, Kolodina AA, Gusakov EA, Komissarov VN, Dorogan IV, Makarova NI, Metelitsa AV, Tkachev VV, Aldoshin SM, Minkin VI.

Beilstein J Org Chem. 2015 Nov 12;11:2179-88. doi: 10.3762/bjoc.11.236. eCollection 2015.

29.

Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention.

Furlan SN, Watkins B, Tkachev V, Flynn R, Cooley S, Ramakrishnan S, Singh K, Giver C, Hamby K, Stempora L, Garrett A, Chen J, Betz KM, Ziegler CG, Tharp GK, Bosinger SE, Promislow DE, Miller JS, Waller EK, Blazar BR, Kean LS.

Sci Transl Med. 2015 Nov 25;7(315):315ra191. doi: 10.1126/scitranslmed.aad3231.

30.

Programmed death-1 controls T cell survival by regulating oxidative metabolism.

Tkachev V, Goodell S, Opipari AW, Hao LY, Franchi L, Glick GD, Ferrara JL, Byersdorfer CA.

J Immunol. 2015 Jun 15;194(12):5789-800. doi: 10.4049/jimmunol.1402180. Epub 2015 May 13.

31.

[The use of transcallosal ventriculostomy to treat complicated forms of aneurismal intracranial hemorrhages].

Tkachev VV, Shagal LV, Muzlaev GG.

Zh Vopr Neirokhir Im N N Burdenko. 2015;79(1):48-57. doi: 10.17116/neiro201579148-57. English, Russian.

32.

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.

Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, Schmitt-Graeff A, Nakae S, Follo M, Wertheimer T, Schwab L, Devlin J, Watkins SC, Duyster J, Ferrara JL, Turnquist HR, Zeiser R, Blazar BR.

Blood. 2015 May 14;125(20):3183-92. doi: 10.1182/blood-2014-10-606830. Epub 2015 Mar 26. Erratum in: Blood. 2016 Sep 1;128(9):1311.

33.

Anaplerotic metabolism of alloreactive T cells provides a metabolic approach to treat graft-versus-host disease.

Glick GD, Rossignol R, Lyssiotis CA, Wahl D, Lesch C, Sanchez B, Liu X, Hao LY, Taylor C, Hurd A, Ferrara JL, Tkachev V, Byersdorfer CA, Boros L, Opipari AW.

J Pharmacol Exp Ther. 2014 Nov;351(2):298-307. doi: 10.1124/jpet.114.218099. Epub 2014 Aug 14.

34.

Water-soluble phenol TS-13 combats acute but not chronic inflammation.

Menshchikova E, Tkachev V, Lemza A, Sharkova T, Kandalintseva N, Vavilin V, Safronova O, Zenkov N.

Inflamm Res. 2014 Sep;63(9):729-40. doi: 10.1007/s00011-014-0746-0. Epub 2014 Jun 3.

PMID:
24888323
35.

Effect of highly mineralized natural water on redox processes in HaCaT keratinocytes.

Zaitseva NS, Chechushkov AV, Kozhin PM, Lemza AE, Tkachev VO, Solomatina MV, Starostenko VA.

Bull Exp Biol Med. 2014 Apr;156(6):810-2. doi: 10.1007/s10517-014-2457-5. Epub 2014 May 3.

PMID:
24824704
36.

Anti-inflammatory activity of TS-13, ARE-inducing phenol antioxidant.

Menshchikova EB, Tkachev VO, Zenkov NK, Lemza AE, Sharkova TV, Kandalintseva NV.

Bull Exp Biol Med. 2013 Jul;155(3):366-9.

PMID:
24137605
37.

Protective effect of ARE-inducing phenol antioxidant TS-13 in chronic inflammation.

Menshchikova EB, Zenkov NK, Tkachev VO, Lemza AE, Kandalintseva NV.

Bull Exp Biol Med. 2013 Jul;155(3):330-4.

PMID:
24137596
38.

Effector T cells require fatty acid metabolism during murine graft-versus-host disease.

Byersdorfer CA, Tkachev V, Opipari AW, Goodell S, Swanson J, Sandquist S, Glick GD, Ferrara JL.

Blood. 2013 Oct 31;122(18):3230-7. doi: 10.1182/blood-2013-04-495515. Epub 2013 Sep 17.

39.

Oxidative stress and free-radical oxidation in bcg granulomatosis development.

Menshchikova E, Zenkov N, Tkachev V, Potapova O, Cherdantseva L, Shkurupiy V.

Oxid Med Cell Longev. 2013;2013:452546. doi: 10.1155/2013/452546. Epub 2013 Apr 23.

40.

[Oxidised dextrans influence on reactive oxygen species generation by murine peritoneal exudate phagocytic cells].

Tkachev VO, Zaĭkovskaia MV, Troitskiĭ AV, Luzgina NG, Shkurupiĭ VA.

Biomed Khim. 2013 Jan-Feb;59(1):81-9. Russian.

PMID:
23650725
41.

Keap1/Nrf2/ARE redox-sensitive signaling system as a pharmacological target.

Zenkov NK, Menshchikova EB, Tkachev VO.

Biochemistry (Mosc). 2013 Jan;78(1):19-36. doi: 10.1134/S0006297913010033. Review.

PMID:
23379556
42.

ARE-inducing phenol antioxidant TC-13 improves survival of Drosophila melanogaster in oxidative stress.

Menshchikova EB, Wisman NY, Zenkov NK, Tkachev VO, Kandalintseva NV.

Bull Exp Biol Med. 2012 Dec;154(2):260-4.

PMID:
23330139
43.

Changes in activity of free radical oxidation processes in the early stages of BCG granulomatosis.

Shkurupiy VA, Menshchikova EB, Tkachev VO, Zenkov NK.

Bull Exp Biol Med. 2012 Dec;154(2):213-6.

PMID:
23330128
44.

[Combination of multiple distal posterior fossa aneurysms with cerebellar AVM].

Tkachev VV, Lepshokov MKh, Kran OI, Muzlaev GG.

Zh Vopr Neirokhir Im N N Burdenko. 2012;76(5):48-52; discussion 52. Russian.

PMID:
23230694
45.

[Stepwise treatment of a patient with seven bilateral cerebral aneurysms].

Tkachev VV, Usachev AA, Kran OI, Muzlaev GG.

Zh Vopr Neirokhir Im N N Burdenko. 2012;76(4):53-8; discussion 59. Russian.

PMID:
23033594
46.

Morphofunctional characteristics of the immune system in CBA and C57Bl/6g mice.

Shkurupiy VA, Tkachev VO, Potapova OV, Luzgina NG, Bugrimova JS, Obedinskaya KS, Zaiceva NS, Chechushkov AV.

Bull Exp Biol Med. 2011 Apr;150(6):725-8.

PMID:
22235428
47.

Mechanism of the Nrf2/Keap1/ARE signaling system.

Tkachev VO, Menshchikova EB, Zenkov NK.

Biochemistry (Mosc). 2011 Apr;76(4):407-22. Review.

PMID:
21585316
48.

Trace elements content and hormonal profiles in women with androgenetic alopecia.

Skalnaya MG, Tkachev VP.

J Trace Elem Med Biol. 2011 Jan;25 Suppl 1:S50-3. doi: 10.1016/j.jtemb.2010.10.006. Epub 2010 Dec 16.

PMID:
21167696
49.

How many antiviral small interfering RNAs may be encoded by the mammalian genomes?

Zabolotneva A, Tkachev V, Filatov F, Buzdin A.

Biol Direct. 2010 Nov 8;5:62. doi: 10.1186/1745-6150-5-62.

50.

Synthetic water-soluble phenolic antioxidant regulates l-arginine metabolism in macrophages: a possible role of Nrf2/ARE.

Tkachev VO, Menshchikova EB, Zenkov NK, Kandalintseva NV, Volsky NN.

Biochemistry (Mosc). 2010 May;75(5):549-53.

PMID:
20632932

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