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Items: 17


Combined inhibition of tumor necrosis factor α and interleukin-17 as a therapeutic opportunity in rheumatoid arthritis: development and characterization of a novel bispecific antibody.

Fischer JA, Hueber AJ, Wilson S, Galm M, Baum W, Kitson C, Auer J, Lorenz SH, Moelleken J, Bader M, Tissot AC, Tan SL, Seeber S, Schett G.

Arthritis Rheumatol. 2015 Jan;67(1):51-62. doi: 10.1002/art.38896.


Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle.

Niewoehner J, Bohrmann B, Collin L, Urich E, Sade H, Maier P, Rueger P, Stracke JO, Lau W, Tissot AC, Loetscher H, Ghosh A, Freskgård PO.

Neuron. 2014 Jan 8;81(1):49-60. doi: 10.1016/j.neuron.2013.10.061.


A VLP-based vaccine against interleukin-1α protects mice from atherosclerosis.

Tissot AC, Spohn G, Jennings GT, Shamshiev A, Kurrer MO, Windak R, Meier M, Viesti M, Hersberger M, Kündig TM, Ricci R, Bachmann MF.

Eur J Immunol. 2013 Mar;43(3):716-22. doi: 10.1002/eji.201242687. Epub 2013 Jan 28.


The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects.

Wiessner C, Wiederhold KH, Tissot AC, Frey P, Danner S, Jacobson LH, Jennings GT, Lüönd R, Ortmann R, Reichwald J, Zurini M, Mir A, Bachmann MF, Staufenbiel M.

J Neurosci. 2011 Jun 22;31(25):9323-31. doi: 10.1523/JNEUROSCI.0293-11.2011.


Versatile virus-like particle carrier for epitope based vaccines.

Tissot AC, Renhofa R, Schmitz N, Cielens I, Meijerink E, Ose V, Jennings GT, Saudan P, Pumpens P, Bachmann MF.

PLoS One. 2010 Mar 23;5(3):e9809. doi: 10.1371/journal.pone.0009809.


Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study.

Tissot AC, Maurer P, Nussberger J, Sabat R, Pfister T, Ignatenko S, Volk HD, Stocker H, Müller P, Jennings GT, Wagner F, Bachmann MF.

Lancet. 2008 Mar 8;371(9615):821-7. doi: 10.1016/S0140-6736(08)60381-5.


A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity.

Ambühl PM, Tissot AC, Fulurija A, Maurer P, Nussberger J, Sabat R, Nief V, Schellekens C, Sladko K, Roubicek K, Pfister T, Rettenbacher M, Volk HD, Wagner F, Müller P, Jennings GT, Bachmann MF.

J Hypertens. 2007 Jan;25(1):63-72.


Reply to 'Blood pressure vaccine shot down by safety concerns'.

Bachmann MF, Nussberger J, Tissot AC, Jennings GT.

Nat Med. 2006 Mar;12(3):270. No abstract available.


Efficient homologous prime-boost strategies for T cell vaccination based on virus-like particles.

Schwarz K, Meijerink E, Speiser DE, Tissot AC, Cielens I, Renhof R, Dishlers A, Pumpens P, Bachmann MF.

Eur J Immunol. 2005 Mar;35(3):816-21.


Structural analysis of mycobacterial and murine hsp60 epitopes in complex with the class I MHC molecule H-2Db.

Ciatto C, Capitani G, Tissot AC, Pecorari F, Plückthun A, Grütter MG.

FEBS Lett. 2003 May 22;543(1-3):11-5.


Virus-like particles as a modular system for novel vaccines.

Lechner F, Jegerlehner A, Tissot AC, Maurer P, Sebbel P, Renner WA, Jennings GT, Bachmann MF.

Intervirology. 2002;45(4-6):212-7. Review.


Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides.

Ciatto C, Tissot AC, Tschopp M, Capitani G, Pecorari F, Plückthun A, Grütter MG.

J Mol Biol. 2001 Oct 5;312(5):1059-71. Erratum in: J Mol Biol 2001 Dec 14;314(5):1257.


Characterizing the functionality of recombinant T-cell receptors in vitro: a pMHC tetramer based approach.

Tissot AC, Pecorari F, Plückthun A.

J Immunol Methods. 2000 Mar 6;236(1-2):147-65.


Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

Gallimore A, Glithero A, Godkin A, Tissot AC, Plückthun A, Elliott T, Hengartner H, Zinkernagel R.

J Exp Med. 1998 May 4;187(9):1383-93.


Importance of two buried salt bridges in the stability and folding pathway of barnase.

Tissot AC, Vuilleumier S, Fersht AR.

Biochemistry. 1996 May 28;35(21):6786-94.


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