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Items: 41

1.

Metabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegans.

Seo Y, Kingsley S, Walker G, Mondoux MA, Tissenbaum HA.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2791-E2800. doi: 10.1073/pnas.1714178115. Epub 2018 Mar 6.

2.

DAF-16: FOXO in the Context of C. elegans.

Tissenbaum HA.

Curr Top Dev Biol. 2018;127:1-21. doi: 10.1016/bs.ctdb.2017.11.007. Epub 2018 Feb 2. Review.

PMID:
29433733
3.

Global Cysteine-Reactivity Profiling during Impaired Insulin/IGF-1 Signaling in C. elegans Identifies Uncharacterized Mediators of Longevity.

Martell J, Seo Y, Bak DW, Kingsley SF, Tissenbaum HA, Weerapana E.

Cell Chem Biol. 2016 Aug 18;23(8):955-66. doi: 10.1016/j.chembiol.2016.06.015. Epub 2016 Aug 4.

4.

Using C. elegans for aging research.

Tissenbaum HA.

Invertebr Reprod Dev. 2015 Jan 30;59(sup1):59-63. Epub 2014 Dec 9.

5.

Uncoupling lifespan and healthspan in Caenorhabditis elegans longevity mutants.

Bansal A, Zhu LJ, Yen K, Tissenbaum HA.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):E277-86. doi: 10.1073/pnas.1412192112. Epub 2015 Jan 5.

6.

Imaging lipid metabolism in live Caenorhabditis elegans using fingerprint vibrations.

Wang P, Liu B, Zhang D, Belew MY, Tissenbaum HA, Cheng JX.

Angew Chem Int Ed Engl. 2014 Oct 27;53(44):11787-92. doi: 10.1002/anie.201406029. Epub 2014 Sep 4.

7.

Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan.

Bansal A, Kwon ES, Conte D Jr, Liu H, Gilchrist MJ, MacNeil LT, Tissenbaum HA.

Longev Healthspan. 2014 Apr 23;3:5. doi: 10.1186/2046-2395-3-5. eCollection 2014.

8.

C. elegans sirtuins.

Viswanathan M, Tissenbaum HA.

Methods Mol Biol. 2013;1077:39-56. doi: 10.1007/978-1-62703-637-5_3.

PMID:
24014398
9.

Complex expression dynamics and robustness in C. elegans insulin networks.

Ritter AD, Shen Y, Fuxman Bass J, Jeyaraj S, Deplancke B, Mukhopadhyay A, Xu J, Driscoll M, Tissenbaum HA, Walhout AJ.

Genome Res. 2013 Jun;23(6):954-65. doi: 10.1101/gr.150466.112. Epub 2013 Mar 28.

10.

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity.

Parker JA, Vazquez-Manrique RP, Tourette C, Farina F, Offner N, Mukhopadhyay A, Orfila AM, Darbois A, Menet S, Tissenbaum HA, Neri C.

J Neurosci. 2012 Sep 5;32(36):12630-40. doi: 10.1523/JNEUROSCI.0277-12.2012.

11.

Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways.

Perrin AJ, Gunda M, Yu B, Yen K, Ito S, Forster S, Tissenbaum HA, Derry WB.

Cell Death Differ. 2013 Jan;20(1):97-107. doi: 10.1038/cdd.2012.101. Epub 2012 Aug 31.

12.

Genetics, life span, health span, and the aging process in Caenorhabditis elegans.

Tissenbaum HA.

J Gerontol A Biol Sci Med Sci. 2012 May;67(5):503-10. doi: 10.1093/gerona/gls088. Epub 2012 Apr 12. Review.

13.

PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism.

Narasimhan SD, Yen K, Bansal A, Kwon ES, Padmanabhan S, Tissenbaum HA.

PLoS Genet. 2011 Apr;7(4):e1001377. doi: 10.1371/journal.pgen.1001377. Epub 2011 Apr 21.

14.

A comparative study of fat storage quantitation in nematode Caenorhabditis elegans using label and label-free methods.

Yen K, Le TT, Bansal A, Narasimhan SD, Cheng JX, Tissenbaum HA.

PLoS One. 2010 Sep 16;5(9). pii: e12810. doi: 10.1371/journal.pone.0012810.

15.

Dietary restriction: standing up for sirtuins.

Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, McBurney M, Nabeshima Y, Neri C, Oberdoerffer P, Pestell RG, Rogina B, Sadoshima J, Sartorelli V, Serrano M, Sinclair DA, Steegborn C, Tatar M, Tissenbaum HA, Tong Q, Tsubota K, Vaquero A, Verdin E.

Science. 2010 Aug 27;329(5995):1012-3; author reply 1013-4. doi: 10.1126/science.329.5995.1012. No abstract available.

16.

DAF-16/Forkhead box O transcription factor: many paths to a single Fork(head) in the road.

Yen K, Narasimhan SD, Tissenbaum HA.

Antioxid Redox Signal. 2011 Feb 15;14(4):623-34. doi: 10.1089/ars.2010.3490. Epub 2010 Nov 30.

17.

A new DAF-16 isoform regulates longevity.

Kwon ES, Narasimhan SD, Yen K, Tissenbaum HA.

Nature. 2010 Jul 22;466(7305):498-502. doi: 10.1038/nature09184. Epub 2010 Jul 7.

18.

InAKTivation of insulin/IGF-1 signaling by dephosphorylation.

Narasimhan SD, Mukhopadhyay A, Tissenbaum HA.

Cell Cycle. 2009 Dec;8(23):3878-84.

19.

Converging pathways in lifespan regulation.

Narasimhan SD, Yen K, Tissenbaum HA.

Curr Biol. 2009 Aug 11;19(15):R657-66. doi: 10.1016/j.cub.2009.06.013. Review.

20.

A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation.

Padmanabhan S, Mukhopadhyay A, Narasimhan SD, Tesz G, Czech MP, Tissenbaum HA.

Cell. 2009 Mar 6;136(5):939-51. doi: 10.1016/j.cell.2009.01.025. Epub 2009 Feb 26.

21.

Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans.

Mukhopadhyay A, Deplancke B, Walhout AJ, Tissenbaum HA.

Nat Protoc. 2008;3(4):698-709. doi: 10.1038/nprot.2008.38.

22.

An endocytic pathway as a target of tubby for regulation of fat storage.

Mukhopadhyay A, Pan X, Lambright DG, Tissenbaum HA.

EMBO Rep. 2007 Oct;8(10):931-8. Epub 2007 Aug 31. Erratum in: EMBO Rep. 2007 Oct;8(10):974.

23.

Reproduction and longevity: secrets revealed by C. elegans.

Mukhopadhyay A, Tissenbaum HA.

Trends Cell Biol. 2007 Feb;17(2):65-71. Epub 2006 Dec 21. Review.

PMID:
17187981
24.

Serotonin's SOS signal.

Tissenbaum HA.

Cell Metab. 2006 Dec;4(6):415-7.

25.

C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

Wang Y, Oh SW, Deplancke B, Luo J, Walhout AJ, Tissenbaum HA.

Mech Ageing Dev. 2006 Sep;127(9):741-7. Epub 2006 Jul 24.

PMID:
16860373
26.

Worming pathways to and from DAF-16/FOXO.

Mukhopadhyay A, Oh SW, Tissenbaum HA.

Exp Gerontol. 2006 Oct;41(10):928-34. Epub 2006 Jul 12. Review.

PMID:
16839734
27.

A gene-centered C. elegans protein-DNA interaction network.

Deplancke B, Mukhopadhyay A, Ao W, Elewa AM, Grove CA, Martinez NJ, Sequerra R, Doucette-Stamm L, Reece-Hoyes JS, Hope IA, Tissenbaum HA, Mango SE, Walhout AJ.

Cell. 2006 Jun 16;125(6):1193-205.

28.

Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation.

Oh SW, Mukhopadhyay A, Dixit BL, Raha T, Green MR, Tissenbaum HA.

Nat Genet. 2006 Feb;38(2):251-7. Epub 2005 Dec 25.

PMID:
16380712
29.

Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.

Wang Y, Tissenbaum HA.

Mech Ageing Dev. 2006 Jan;127(1):48-56. Epub 2005 Nov 8.

PMID:
16280150
30.

Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans.

Grabowski MM, Svrzikapa N, Tissenbaum HA.

Mech Ageing Dev. 2005 Dec;126(12):1314-21. Epub 2005 Sep 21.

PMID:
16181657
31.

C. elegans tubby regulates life span and fat storage by two independent mechanisms.

Mukhopadhyay A, Deplancke B, Walhout AJ, Tissenbaum HA.

Cell Metab. 2005 Jul;2(1):35-42.

32.

JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, Tissenbaum HA.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4494-9. Epub 2005 Mar 14.

33.

Model organisms as a guide to mammalian aging.

Tissenbaum HA, Guarente L.

Dev Cell. 2002 Jan;2(1):9-19. Review.

35.

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.

Tissenbaum HA, Guarente L.

Nature. 2001 Mar 8;410(6825):227-30.

PMID:
11242085
36.

A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum.

Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G.

Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):460-5.

37.
38.

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.

Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G.

Nature. 1997 Oct 30;389(6654):994-9.

PMID:
9353126
39.

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.

Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G.

Science. 1997 Aug 15;277(5328):942-6.

40.

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans.

Morris JZ, Tissenbaum HA, Ruvkun G.

Nature. 1996 Aug 8;382(6591):536-9.

PMID:
8700226

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