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Items: 1 to 50 of 56

1.

The structure of glucose-1-phosphate thymidylyltransferase from Mycobacterium tuberculosis reveals the location of an essential magnesium ion in the RmlA-type enzymes.

Brown HA, Thoden JB, Tipton PA, Holden HM.

Protein Sci. 2018 Feb;27(2):441-450. doi: 10.1002/pro.3333. Epub 2017 Nov 9.

PMID:
29076563
2.

Structural and Biochemical Investigation of PglF from Campylobacter jejuni Reveals a New Mechanism for a Member of the Short Chain Dehydrogenase/Reductase Superfamily.

Riegert AS, Thoden JB, Schoenhofen IC, Watson DC, Young NM, Tipton PA, Holden HM.

Biochemistry. 2017 Nov 14;56(45):6030-6040. doi: 10.1021/acs.biochem.7b00910. Epub 2017 Nov 3.

PMID:
29053280
3.

Biochemical Characterization of WbkC, an N-Formyltransferase from Brucella melitensis.

Riegert AS, Chantigian DP, Thoden JB, Tipton PA, Holden HM.

Biochemistry. 2017 Jul 18;56(28):3657-3668. doi: 10.1021/acs.biochem.7b00494. Epub 2017 Jul 5.

4.

Structural Studies on a Glucosamine/Glucosaminide N-Acetyltransferase.

Dopkins BJ, Tipton PA, Thoden JB, Holden HM.

Biochemistry. 2016 Aug 16;55(32):4495-508. doi: 10.1021/acs.biochem.6b00536. Epub 2016 Aug 4.

5.

Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products.

Zhu J, Lippa GM, Gulick AM, Tipton PA.

Biochemistry. 2015 Apr 28;54(16):2659-69. doi: 10.1021/acs.biochem.5b00255. Epub 2015 Apr 20.

PMID:
25866990
6.

A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5.

Wilkins JM, McConnell C, Tipton PA, Hannink M.

J Biol Chem. 2014 Sep 5;289(36):25137-48. doi: 10.1074/jbc.M114.565549. Epub 2014 Jul 10.

7.

Evolutionary history and metabolic insights of ancient mammalian uricases.

Kratzer JT, Lanaspa MA, Murphy MN, Cicerchi C, Graves CL, Tipton PA, Ortlund EA, Johnson RJ, Gaucher EA.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3763-8. doi: 10.1073/pnas.1320393111. Epub 2014 Feb 18.

8.

Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation.

Riley LM, Weadge JT, Baker P, Robinson H, Codée JD, Tipton PA, Ohman DE, Howell PL.

J Biol Chem. 2013 Aug 2;288(31):22299-314. doi: 10.1074/jbc.M113.484931. Epub 2013 Jun 18.

9.

Functional characterization of AlgL, an alginate lyase from Pseudomonas aeruginosa.

Farrell EK, Tipton PA.

Biochemistry. 2012 Dec 21;51(51):10259-66. doi: 10.1021/bi301425r. Epub 2012 Dec 13.

10.

The enzymes of bacterial census and censorship.

Fast W, Tipton PA.

Trends Biochem Sci. 2012 Jan;37(1):7-14. doi: 10.1016/j.tibs.2011.10.001. Epub 2011 Nov 16. Review.

11.

Kinetic consequences of replacing the internucleotide phosphorus atoms in DNA with arsenic.

Fekry MI, Tipton PA, Gates KS.

ACS Chem Biol. 2011 Feb 18;6(2):127-30. doi: 10.1021/cb2000023. Epub 2011 Jan 26.

PMID:
21268588
12.

Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa AlgX.

Weadge JT, Yip PP, Robinson H, Arnett K, Tipton PA, Howell PL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):588-91. doi: 10.1107/S1744309110011851. Epub 2010 Apr 30.

13.

Reactivity and reaction order in acylhomoserine lactone formation by Pseudomonas aeruginosa RhlI.

Raychaudhuri A, Tullock A, Tipton PA.

Biochemistry. 2008 Mar 4;47(9):2893-8. doi: 10.1021/bi702009n. Epub 2008 Jan 26.

PMID:
18220361
14.

Chemical mechanism and specificity of the C5-mannuronan epimerase reaction.

Jerga A, Stanley MD, Tipton PA.

Biochemistry. 2006 Aug 1;45(30):9138-44.

PMID:
16866359
15.

Urate to allantoin, specifically (S)-allantoin.

Tipton PA.

Nat Chem Biol. 2006 Mar;2(3):124-5. No abstract available.

PMID:
16485000
16.
17.

Update on ureide degradation in legumes.

Todd CD, Tipton PA, Blevins DG, Piedras P, Pineda M, Polacco JC.

J Exp Bot. 2006;57(1):5-12. Epub 2005 Nov 29. Review.

PMID:
16317038
18.

Procatalytic ligand strain. Ionization and perturbation of 8-nitroxanthine at the urate oxidase active site.

Doll C, Bell AF, Power N, Tonge PJ, Tipton PA.

Biochemistry. 2005 Aug 30;44(34):11440-6.

PMID:
16114880
19.
20.
21.

Chemical mechanism and substrate specificity of RhlI, an acylhomoserine lactone synthase from Pseudomonas aeruginosa.

Raychaudhuri A, Jerga A, Tipton PA.

Biochemistry. 2005 Mar 1;44(8):2974-81.

PMID:
15723540
22.

Protocol for amplification of GC-rich sequences from Pseudomonas aeruginosa.

Raychaudhuri A, Tipton PA.

Biotechniques. 2004 Nov;37(5):752, 754, 756. No abstract available.

23.

Detailed kinetic studies of an aggregating inhibitor; inhibition of phosphomannomutase/phosphoglucomutase by disperse blue 56.

Liu HY, Wang Z, Regni C, Zou X, Tipton PA.

Biochemistry. 2004 Jul 13;43(27):8662-9.

PMID:
15236574
24.

Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.

Regni C, Naught L, Tipton PA, Beamer LJ.

Structure. 2004 Jan;12(1):55-63.

25.

Roles of active site residues in Pseudomonas aeruginosa phosphomannomutase/phosphoglucomutase.

Naught LE, Regni C, Beamer LJ, Tipton PA.

Biochemistry. 2003 Aug 26;42(33):9946-51.

PMID:
12924943
26.

A familiar motif in a new context: the catalytic mechanism of hydroxyisourate hydrolase.

Raychaudhuri A, Tipton PA.

Biochemistry. 2003 Jun 10;42(22):6848-52.

PMID:
12779339
27.

Crystal structure of GDP-mannose dehydrogenase: a key enzyme of alginate biosynthesis in P. aeruginosa.

Snook CF, Tipton PA, Beamer LJ.

Biochemistry. 2003 Apr 29;42(16):4658-68.

PMID:
12705829
28.

General base catalysis in the urate oxidase reaction: evidence for a novel Thr-Lys catalytic diad.

Imhoff RD, Power NP, Borrok MJ, Tipton PA.

Biochemistry. 2003 Apr 15;42(14):4094-100.

PMID:
12680763
30.
31.
32.

Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD.

Karsten WE, Tipton PA, Cook PF.

Biochemistry. 2002 Oct 8;41(40):12193-9.

PMID:
12356321
34.

Maximizing aesthetics, fit, and maintenance of the full-arch implant-supported porcelain-fused-to-metal restoration.

Tipton PA.

Pract Proced Aesthet Dent. 2002 Jun-Jul;14(5):395-400; quiz 402.

PMID:
12134391
35.
36.
37.

Aesthetic tooth alignment using etched porcelain restorations.

Tipton PA.

Pract Proced Aesthet Dent. 2001 Sep;13(7):551-5; quiz 556-8.

PMID:
11685834
38.

Crystallization and initial crystallographic analysis of phosphomannomutase/phosphoglucomutase from Pseudomonas aeruginosa.

Regni CA, Tipton PA, Beamer LJ.

Acta Crystallogr D Biol Crystallogr. 2000 Jun;56(Pt 6):761-2.

PMID:
10818357
39.

Identification and purification of hydroxyisourate hydrolase, a novel ureide-metabolizing enzyme.

Sarma AD, Serfozo P, Kahn K, Tipton PA.

J Biol Chem. 1999 Nov 26;274(48):33863-5.

40.

Spectroscopic characterization of intermediates in the urate oxidase reaction.

Kahn K, Tipton PA.

Biochemistry. 1998 Aug 18;37(33):11651-9.

PMID:
9709003
41.

Kinetic mechanism and cofactor content of soybean root nodule urate oxidase.

Kahn K, Tipton PA.

Biochemistry. 1997 Apr 22;36(16):4731-8.

PMID:
9125493
44.

A colorimetric assay for cytokinin oxidase.

Libreros-Minotta CA, Tipton PA.

Anal Biochem. 1995 Nov 1;231(2):339-41.

PMID:
8594982
45.

Substrate determinants of the course of tartrate dehydrogenase-catalyzed reactions.

Serfozo P, Tipton PA.

Biochemistry. 1995 Jun 6;34(22):7517-24.

PMID:
7779796
46.

Tartrate dehydrogenase-oxalate complexes: formation of a stable analog of a reaction intermediate complex.

Beecher BS, Koder RL, Tipton PA.

Arch Biochem Biophys. 1994 Dec;315(2):255-61.

PMID:
7986065
47.
48.
49.

Pulsed EPR analysis of tartrate dehydrogenase active-site complexes.

Tipton PA, Peisach J.

Biochemistry. 1991 Jan 22;30(3):739-44.

PMID:
1846305
50.

Characterization of the multiple catalytic activities of tartrate dehydrogenase.

Tipton PA, Peisach J.

Biochemistry. 1990 Feb 20;29(7):1749-56.

PMID:
2184888

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