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Items: 1 to 50 of 126


Wolfberry-Derived Zeaxanthin Dipalmitate Attenuates Ethanol-Induced Hepatic Damage.

Gao H, Lv Y, Liu Y, Li J, Wang X, Zhou Z, Tipoe GL, Ouyang S, Guo Y, Zhang J, Hao X, Li W, Koike K, So KF, Xiao J.

Mol Nutr Food Res. 2019 Jun;63(11):e1801339. doi: 10.1002/mnfr.201801339. Epub 2019 Apr 10.


Cross-sectional area of the median nerve at the wrist: Comparison of sonographic, MRI, and cadaveric measurements.

Lee RKL, Griffith JF, Ng AWH, Tipoe GL, Chan AWH, Wong CWY, Tse WL, Ho PC.

J Clin Ultrasound. 2019 Mar;47(3):122-127. doi: 10.1002/jcu.22647. Epub 2018 Dec 29.


Lycium barbarum polysaccharides improve hepatic injury through NFkappa-B and NLRP3/6 pathways in a methionine choline deficient diet steatohepatitis mouse model.

Xiao J, Wang F, Liong EC, So KF, Tipoe GL.

Int J Biol Macromol. 2018 Dec;120(Pt B):1480-1489. doi: 10.1016/j.ijbiomac.2018.09.151. Epub 2018 Sep 25.


Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway.

Xiao J, Xing F, Liu Y, Lv Y, Wang X, Ling MT, Gao H, Ouyang S, Yang M, Zhu J, Xia Y, So KF, Tipoe GL.

Acta Pharm Sin B. 2018 Jul;8(4):575-586. doi: 10.1016/j.apsb.2017.10.003. Epub 2017 Nov 10.


Lycium barbarum Polysaccharide Supplementation Improves Alcoholic Liver Injury in Female Mice by Inhibiting Stearoyl-CoA Desaturase 1.

Wang F, Tipoe GL, Yang C, Nanji AA, Hao X, So KF, Xiao J.

Mol Nutr Food Res. 2018 Jul;62(13):e1800144. doi: 10.1002/mnfr.201800144. Epub 2018 Jun 10.


LncRNA HANR Promotes Tumorigenesis and Increase of Chemoresistance in Hepatocellular Carcinoma.

Xiao J, Lv Y, Jin F, Liu Y, Ma Y, Xiong Y, Liu L, Zhang S, Sun Y, Tipoe GL, Hong A, Xing F, Wang X.

Cell Physiol Biochem. 2017;43(5):1926-1938. doi: 10.1159/000484116. Epub 2017 Oct 20.


Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration.

Lam CS, Li JJ, Tipoe GL, Youdim MBH, Fung ML.

PLoS One. 2017 Jun 9;12(6):e0177940. doi: 10.1371/journal.pone.0177940. eCollection 2017.


Melatonin Attenuates Pulmonary Hypertension in Chronically Hypoxic Rats.

Hung MW, Yeung HM, Lau CF, Poon AMS, Tipoe GL, Fung ML.

Int J Mol Sci. 2017 May 24;18(6). pii: E1125. doi: 10.3390/ijms18061125.


M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus.

Lam CS, Tipoe GL, Wong JK, Youdim MB, Fung ML.

PLoS One. 2016 Nov 21;11(11):e0166966. doi: 10.1371/journal.pone.0166966. eCollection 2016.


Inhibition of caspase-9 aggravates acute liver injury through suppression of cytoprotective autophagy.

Guo R, Lin B, Pan JF, Liong EC, Xu AM, Youdim M, Fung ML, So KF, Tipoe GL.

Sci Rep. 2016 Sep 1;6:32447. doi: 10.1038/srep32447.


Combined acoustic radiation force impulse, aminotransferase to platelet ratio index and Forns index assessment for hepatic fibrosis grading in hepatitis B.

Dong CF, Xiao J, Shan LB, Li HY, Xiong YJ, Yang GL, Liu J, Yao SM, Li SX, Le XH, Yuan J, Zhou BP, Tipoe GL, Liu YX.

World J Hepatol. 2016 May 18;8(14):616-24. doi: 10.4254/wjh.v8.i14.616.


Inhibition of miR-200c Restores Endothelial Function in Diabetic Mice Through Suppression of COX-2.

Zhang H, Liu J, Qu D, Wang L, Luo JY, Lau CW, Liu P, Gao Z, Tipoe GL, Lee HK, Ng CF, Ma RC, Yao X, Huang Y.

Diabetes. 2016 May;65(5):1196-207. doi: 10.2337/db15-1067. Epub 2016 Jan 28.


Inflammasomes in non-alcoholic fatty liver disease.

Xiao J, Tipoe GL.

Front Biosci (Landmark Ed). 2016 Jan 1;21:683-95. Review.


Comparative proteomic analysis of fibrotic liver of rats fed high fat diet contained lard versus corn oil.

Wang H, Sit WH, Tipoe GL, Liu Z, Wan JM.

Clin Nutr. 2017 Feb;36(1):198-208. doi: 10.1016/j.clnu.2015.10.015. Epub 2015 Nov 7.


Bee's honey attenuates non-alcoholic steatohepatitis-induced hepatic injury through the regulation of thioredoxin-interacting protein-NLRP3 inflammasome pathway.

Xiao J, Liu Y, Xing F, Leung TM, Liong EC, Tipoe GL.

Eur J Nutr. 2016 Jun;55(4):1465-77. doi: 10.1007/s00394-015-0964-4. Epub 2015 Jul 2.


Antioxidant treatment enhances human mesenchymal stem cell anti-stress ability and therapeutic efficacy in an acute liver failure model.

Zeng W, Xiao J, Zheng G, Xing F, Tipoe GL, Wang X, He C, Chen ZY, Liu Y.

Sci Rep. 2015 Jun 9;5:11100. doi: 10.1038/srep11100.


Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease.

Guo R, Liong EC, So KF, Fung ML, Tipoe GL.

Hepatobiliary Pancreat Dis Int. 2015 Apr;14(2):139-44. Review.


A novel antioxidant multitarget iron chelator M30 protects hepatocytes against ethanol-induced injury.

Xiao J, Lv Y, Lin B, Tipoe GL, Youdim MB, Xing F, Liu Y.

Oxid Med Cell Longev. 2015;2015:607271. doi: 10.1155/2015/607271. Epub 2015 Feb 4.


Neuroprotective mechanism of Lycium barbarum polysaccharides against hippocampal-dependent spatial memory deficits in a rat model of obstructive sleep apnea.

Lam CS, Tipoe GL, So KF, Fung ML.

PLoS One. 2015 Feb 25;10(2):e0117990. doi: 10.1371/journal.pone.0117990. eCollection 2015.


Retinal structure and function preservation by polysaccharides of wolfberry in a mouse model of retinal degeneration.

Wang K, Xiao J, Peng B, Xing F, So KF, Tipoe GL, Lin B.

Sci Rep. 2014 Dec 23;4:7601. doi: 10.1038/srep07601.


Cyclooxygenase-1 serves a vital hepato-protective function in chemically induced acute liver injury.

Xiao J, Liong EC, Huang H, On Tse W, Lau KS, Pan J, Nanji AA, Fung ML, Xing F, Tipoe GL.

Toxicol Sci. 2015 Feb;143(2):430-40. doi: 10.1093/toxsci/kfu244. Epub 2014 Nov 27.


Melatonin attenuates intermittent hypoxia-induced lipid peroxidation and local inflammation in rat adrenal medulla.

Liu Y, Tipoe GL, Fung ML.

Int J Mol Sci. 2014 Oct 13;15(10):18437-52. doi: 10.3390/ijms151018437.


Differential protective effects of extra virgin olive oil and corn oil in liver injury: a proteomic study.

Wang H, Sit WH, Tipoe GL, Wan JM.

Food Chem Toxicol. 2014 Dec;74:131-8. doi: 10.1016/j.fct.2014.09.002. Epub 2014 Oct 7.


Cyclooxygenase-2-dependent oxidative stress mediates palmitate-induced impairment of endothelium-dependent relaxations in mouse arteries.

Gao Z, Zhang H, Liu J, Lau CW, Liu P, Chen ZY, Lee HK, Tipoe GL, Ho HM, Yao X, Huang Y.

Biochem Pharmacol. 2014 Oct 15;91(4):474-82. doi: 10.1016/j.bcp.2014.08.009. Epub 2014 Aug 19.


Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model.

Xiao J, Xing F, Huo J, Fung ML, Liong EC, Ching YP, Xu A, Chang RC, So KF, Tipoe GL.

Sci Rep. 2014 Jul 7;4:5587. doi: 10.1038/srep05587.


Suppression of microglial activation is neuroprotective in a mouse model of human retinitis pigmentosa.

Peng B, Xiao J, Wang K, So KF, Tipoe GL, Lin B.

J Neurosci. 2014 Jun 11;34(24):8139-50. doi: 10.1523/JNEUROSCI.5200-13.2014.


Primary care in Asia: a call for compulsory vocational training.

Chan TK, Lee CY, Yau SK, Tipoe GL.

Br J Gen Pract. 2014 Jun;64(623):e381-3. doi: 10.3399/bjgp14X680281. Review. No abstract available.


Lycium barbarum polysaccharide attenuates alcoholic cellular injury through TXNIP-NLRP3 inflammasome pathway.

Xiao J, Zhu Y, Liu Y, Tipoe GL, Xing F, So KF.

Int J Biol Macromol. 2014 Aug;69:73-8. doi: 10.1016/j.ijbiomac.2014.05.034. Epub 2014 May 22.


Zeaxanthin dipalmitate therapeutically improves hepatic functions in an alcoholic fatty liver disease model through modulating MAPK pathway.

Xiao J, Wang J, Xing F, Han T, Jiao R, Liong EC, Fung ML, So KF, Tipoe GL.

PLoS One. 2014 Apr 16;9(4):e95214. doi: 10.1371/journal.pone.0095214. eCollection 2014.


Recent advances in the herbal treatment of non-alcoholic Fatty liver disease.

Xiao J, Fai So K, Liong EC, Tipoe GL.

J Tradit Complement Med. 2013 Apr;3(2):88-94. doi: 10.4103/2225-4110.110411. Review.


Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia.

Lam SY, Liu Y, Ng KM, Liong EC, Tipoe GL, Leung PS, Fung ML.

Exp Physiol. 2014 Jan;99(1):220-31. doi: 10.1113/expphysiol.2013.074591. Epub 2013 Sep 13.


Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitis-induced injury.

Xiao J, Liong EC, Ching YP, Chang RC, Fung ML, Xu AM, So KF, Tipoe GL.

Nutr Diabetes. 2013 Jul 22;3:e81. doi: 10.1038/nutd.2013.22.


Melatonin ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in rats with chronic intermittent hypoxia.

Hung MW, Kravtsov GM, Lau CF, Poon AM, Tipoe GL, Fung ML.

J Pineal Res. 2013 Oct;55(3):247-56. doi: 10.1111/jpi.12067. Epub 2013 Jul 22.


Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy.

Xiao J, Guo R, Fung ML, Liong EC, Chang RC, Ching YP, Tipoe GL.

Evid Based Complement Alternat Med. 2013;2013:642920. doi: 10.1155/2013/642920. Epub 2013 Jun 19.


Should we continue treatment for M? The benefits of living.

Chan TK, Tipoe GL.

J Med Ethics. 2014 Feb;40(2):131-3. doi: 10.1136/medethics-2012-101118. Epub 2013 Apr 26.


Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges.

Xiao J, Guo R, Fung ML, Liong EC, Tipoe GL.

Hepatobiliary Pancreat Dis Int. 2013 Apr;12(2):125-35. Review.


Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways.

Xiao J, Ho CT, Liong EC, Nanji AA, Leung TM, Lau TY, Fung ML, Tipoe GL.

Eur J Nutr. 2014 Feb;53(1):187-99. doi: 10.1007/s00394-013-0516-8. Epub 2013 Mar 21.


The best interests of persistently vegetative patients: to die rather that to live?

Chan TK, Tipoe GL.

J Med Ethics. 2014 Mar;40(3):202-4. doi: 10.1136/medethics-2012-101117. Epub 2013 Feb 6.


Hepatic response to chronic hypoxia in experimental rat model through HIF-1 alpha, activator protein-1 and NF-kappa B.

Lau TY, Xiao J, Liong EC, Liao L, Leung TM, Nanji AA, Fung ML, Tipoe GL.

Histol Histopathol. 2013 Apr;28(4):463-71. Epub 2013 Jan 16.


A public opinion survey: is presumed consent the answer to kidney shortage in Hong Kong?

Chan TK, Cowling BJ, Tipoe GL.

BMJ Open. 2013 Jan 3;3(1). pii: e002013. doi: 10.1136/bmjopen-2012-002013.


Upregulation of pituitary adenylate cyclase activating polypeptide and its receptor expression in the rat carotid body in chronic and intermittent hypoxia.

Lam SY, Liu Y, Liong EC, Tipoe GL, Fung ML.

Adv Exp Med Biol. 2012;758:301-6. doi: 10.1007/978-94-007-4584-1_41.


Antibiotics increase gut metabolism and antioxidant proteins and decrease acute phase response and necrotizing enterocolitis in preterm neonates.

Jiang P, Jensen ML, Cilieborg MS, Thymann T, Wan JM, Sit WH, Tipoe GL, Sangild PT.

PLoS One. 2012;7(9):e44929. doi: 10.1371/journal.pone.0044929. Epub 2012 Sep 13.


Evaluation of liver fibrosis by investigation of hepatic parenchymal perfusion using contrast-enhanced ultrasound: an animal study.

Ying M, Leung G, Lau TY, Tipoe GL, Lee ES, Yuen QW, Huang YP, Zheng YP.

J Clin Ultrasound. 2012 Oct;40(8):462-70. doi: 10.1002/jcu.21969. Epub 2012 Jul 30.


New halogenated disinfection byproducts in swimming pool water and their permeability across skin.

Xiao F, Zhang X, Zhai H, Lo IM, Tipoe GL, Yang M, Pan Y, Chen G.

Environ Sci Technol. 2012 Jul 3;46(13):7112-9. doi: 10.1021/es3010656. Epub 2012 Jun 22.


Thromboxane inhibitors attenuate inflammatory and fibrotic changes in rat liver despite continued ethanol administrations.

Nanji AA, Liong EC, Xiao J, Tipoe GL.

Alcohol Clin Exp Res. 2013 Jan;37(1):31-9. doi: 10.1111/j.1530-0277.2012.01838.x. Epub 2012 Jun 7.


Voices of donors: case reports of body donation in Hong Kong.

Chiu HY, Ng KS, Ma SK, Chan CH, Ng SW, Tipoe GL, Chan LK.

Anat Sci Educ. 2012 Sep-Oct;5(5):295-300. doi: 10.1002/ase.1280. Epub 2012 Apr 24.


A new technique of single portal endoscopic carpal tunnel release.

Ip WY, Sweed TA, Fung KK, Tipoe GL, Pun TS.

Tech Hand Up Extrem Surg. 2012 Mar;16(1):27-9. doi: 10.1097/BTH.0b013e318230db42.


Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model.

Xiao J, Ching YP, Liong EC, Nanji AA, Fung ML, Tipoe GL.

Eur J Nutr. 2013 Feb;52(1):179-91. doi: 10.1007/s00394-012-0301-0. Epub 2012 Jan 26.

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