Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 98


Changes in microarchitecture of atherosclerotic calcification assessed by 18F-NaF PET and CT after a progressive exercise regimen in hyperlipidemic mice.

Hsu JJ, Fong F, Patel R, Qiao R, Lo K, Soundia A, Chang CC, Le V, Tseng CH, Demer LL, Tintut Y.

J Nucl Cardiol. 2020 Jan 2. doi: 10.1007/s12350-019-02004-3. [Epub ahead of print]


Regulation of calcific vascular and valvular disease by nuclear receptors.

Sallam T, Tintut Y, Demer LL.

Curr Opin Lipidol. 2019 Oct;30(5):357-363. doi: 10.1097/MOL.0000000000000632.


Interactive and Multifactorial Mechanisms of Calcific Vascular and Valvular Disease.

Demer LL, Tintut Y.

Trends Endocrinol Metab. 2019 Sep;30(9):646-657. doi: 10.1016/j.tem.2019.06.001. Epub 2019 Jul 3. Review.


Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation.

Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang CC, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK.

JCI Insight. 2019 Apr 11;5. pii: 124460. doi: 10.1172/jci.insight.124460.


Lipoproteins in Cardiovascular Calcification: Potential Targets and Challenges.

Tintut Y, Hsu JJ, Demer LL.

Front Cardiovasc Med. 2018 Nov 23;5:172. doi: 10.3389/fcvm.2018.00172. eCollection 2018. Review.


Multiscale light-sheet for rapid imaging of cardiopulmonary system.

Ding Y, Ma J, Langenbacher AD, Baek KI, Lee J, Chang CC, Hsu JJ, Kulkarni RP, Belperio J, Shi W, Ranjbarvaziri S, Ardehali R, Tintut Y, Demer LL, Chen JN, Fei P, Packard RRS, Hsiai TK.

JCI Insight. 2018 Aug 23;3(16). pii: 121396. doi: 10.1172/jci.insight.121396. eCollection 2018 Aug 23. Review.


Steroid Hormone Vitamin D: Implications for Cardiovascular Disease.

Demer LL, Hsu JJ, Tintut Y.

Circ Res. 2018 May 25;122(11):1576-1585. doi: 10.1161/CIRCRESAHA.118.311585. Review.


Effects of teriparatide on morphology of aortic calcification in aged hyperlipidemic mice.

Hsu JJ, Lu J, Umar S, Lee JT, Kulkarni RP, Ding Y, Chang CC, Hsiai TK, Hokugo A, Gkouveris I, Tetradis S, Nishimura I, Demer LL, Tintut Y.

Am J Physiol Heart Circ Physiol. 2018 Jun 1;314(6):H1203-H1213. doi: 10.1152/ajpheart.00718.2017. Epub 2018 Feb 16.


Rigor and Reproducibility in Analysis of Vascular Calcification.

Demer LL, Tintut Y, Nguyen KL, Hsiai T, Lee JT.

Circ Res. 2017 Apr 14;120(8):1240-1242. doi: 10.1161/CIRCRESAHA.116.310326. Review. No abstract available.


Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells.

Masuda M, Miyazaki-Anzai S, Keenan AL, Shiozaki Y, Okamura K, Chick WS, Williams K, Zhao X, Rahman SM, Tintut Y, Adams CM, Miyazaki M.

JCI Insight. 2016 Nov 3;1(18):e88646. doi: 10.1172/jci.insight.88646.


Reply: Evolutionary approach sheds light on the significance of vascular calcification.

Demer LL, Tintut Y.

Trends Cardiovasc Med. 2017 Jan;27(1):72. doi: 10.1016/j.tcm.2016.06.001. Epub 2016 Jul 7. No abstract available.


Cell-matrix mechanics and pattern formation in inflammatory cardiovascular calcification.

Hsu JJ, Lim J, Tintut Y, Demer LL.

Heart. 2016 Nov 1;102(21):1710-1715. doi: 10.1136/heartjnl-2016-309667. Epub 2016 Jul 12. Review.


Inflammation Drives Retraction, Stiffening, and Nodule Formation via Cytoskeletal Machinery in a Three-Dimensional Culture Model of Aortic Stenosis.

Lim J, Ehsanipour A, Hsu JJ, Lu J, Pedego T, Wu A, Walthers CM, Demer LL, Seidlits SK, Tintut Y.

Am J Pathol. 2016 Sep;186(9):2378-89. doi: 10.1016/j.ajpath.2016.05.003. Epub 2016 Jul 5.


COMP-lex Mechanics: Matricrine Signaling.

Tintut Y, Demer LL.

Circ Res. 2016 Jul 8;119(2):184-6. doi: 10.1161/CIRCRESAHA.116.309121. No abstract available.


Protective Role of Smad6 in Inflammation-Induced Valvular Cell Calcification.

Li X, Lim J, Lu J, Pedego TM, Demer L, Tintut Y.

J Cell Biochem. 2015 Oct;116(10):2354-64. doi: 10.1002/jcb.25186.


Exosomes: nanosized cellular messages.

Tintut Y, Demer LL.

Circ Res. 2015 Apr 10;116(8):1281-3. doi: 10.1161/CIRCRESAHA.115.306324. No abstract available.


The leading edge of vascular calcification.

Demer LL, Tintut Y.

Trends Cardiovasc Med. 2015 May;25(4):275-7. doi: 10.1016/j.tcm.2014.11.010. Epub 2014 Dec 3. No abstract available.


Hyperlipidemia affects multiscale structure and strength of murine femur.

Ascenzi MG, Lutz A, Du X, Klimecky L, Kawas N, Hourany T, Jahng J, Chin J, Tintut Y, Nackenhors U, Keyak J.

J Biomech. 2014 Jul 18;47(10):2436-43. doi: 10.1016/j.jbiomech.2014.04.006. Epub 2014 Apr 16.


Inflammatory, metabolic, and genetic mechanisms of vascular calcification.

Demer LL, Tintut Y.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):715-23. doi: 10.1161/ATVBAHA.113.302070. Review.


FGF23 protein expression in coronary arteries is associated with impaired kidney function.

van Venrooij NA, Pereira RC, Tintut Y, Fishbein MC, Tumber N, Demer LL, Salusky IB, Wesseling-Perry K.

Nephrol Dial Transplant. 2014 Aug;29(8):1525-32. doi: 10.1093/ndt/gft523. Epub 2014 Jan 23.


The effects of hyperlipidemia on implant osseointegration in the mouse femur.

Keuroghlian A, Barroso AD, Kirikian G, Bezouglaia O, Tintut Y, Tetradis S, Moy P, Pirih F, Aghaloo T.

J Oral Implantol. 2015 Apr;41(2):e7-e11. doi: 10.1563/AAID-JOI-D-13-00105. Epub 2013 Dec 2.


Effects of bioactive lipids and lipoproteins on bone.

Tintut Y, Demer LL.

Trends Endocrinol Metab. 2014 Feb;25(2):53-9. doi: 10.1016/j.tem.2013.10.001. Epub 2013 Oct 30. Review.


Roles of parathyroid hormone (PTH) receptor and reactive oxygen species in hyperlipidemia-induced PTH resistance in preosteoblasts.

Li X, Garcia J, Lu J, Iriana S, Kalajzic I, Rowe D, Demer LL, Tintut Y.

J Cell Biochem. 2014 Jan;115(1):179-88. doi: 10.1002/jcb.24648.


Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice.

Lu J, Cheng H, Atti E, Shih DM, Demer LL, Tintut Y.

Biochem Biophys Res Commun. 2013 Feb 1;431(1):19-24. doi: 10.1016/j.bbrc.2012.12.114. Epub 2013 Jan 3.


Regulatory circuits controlling vascular cell calcification.

Sallam T, Cheng H, Demer LL, Tintut Y.

Cell Mol Life Sci. 2013 Sep;70(17):3187-97. doi: 10.1007/s00018-012-1231-y. Epub 2012 Dec 27. Review.


Atmospheric ultrafine particles promote vascular calcification via the NF-κB signaling pathway.

Li R, Mittelstein D, Kam W, Pakbin P, Du Y, Tintut Y, Navab M, Sioutas C, Hsiai T.

Am J Physiol Cell Physiol. 2013 Feb 15;304(4):C362-9. doi: 10.1152/ajpcell.00322.2012. Epub 2012 Dec 12.


Preferred mitotic orientation in pattern formation by vascular mesenchymal cells.

Wong MN, Nguyen TP, Chen TH, Hsu JJ, Zeng X, Saw A, Demer EM, Zhao X, Tintut Y, Demer LL.

Am J Physiol Heart Circ Physiol. 2012 Dec 15;303(12):H1411-7. doi: 10.1152/ajpheart.00625.2012. Epub 2012 Oct 12.


Enhanced mineralization potential of vascular cells from SM22α-Rankl (tg) mice.

Morony S, Sage AP, Corbin T, Lu J, Tintut Y, Demer LL.

Calcif Tissue Int. 2012 Dec;91(6):379-86. doi: 10.1007/s00223-012-9655-9. Epub 2012 Oct 9.


Directing tissue morphogenesis via self-assembly of vascular mesenchymal cells.

Chen TH, Zhu X, Pan L, Zeng X, Garfinkel A, Tintut Y, Demer LL, Zhao X, Ho CM.

Biomaterials. 2012 Dec;33(35):9019-26. doi: 10.1016/j.biomaterials.2012.08.067. Epub 2012 Sep 23.


Focal high cell density generates a gradient of patterns in self-organizing vascular mesenchymal cells.

Cheng H, Reddy A, Sage A, Lu J, Garfinkel A, Tintut Y, Demer LL.

J Vasc Res. 2012;49(5):441-6. doi: 10.1159/000339568. Epub 2012 Jul 11.


Patterns of periodic holes created by increased cell motility.

Chen TH, Guo C, Zhao X, Yao Y, Boström KI, Wong MN, Tintut Y, Demer LL, Ho CM, Garfinkel A.

Interface Focus. 2012 Aug 6;2(4):457-64. doi: 10.1098/rsfs.2012.0001. Epub 2012 Mar 28.


Left-right symmetry breaking in tissue morphogenesis via cytoskeletal mechanics.

Chen TH, Hsu JJ, Zhao X, Guo C, Wong MN, Huang Y, Li Z, Garfinkel A, Ho CM, Tintut Y, Demer LL.

Circ Res. 2012 Feb 17;110(4):551-9. doi: 10.1161/CIRCRESAHA.111.255927. Epub 2012 Jan 5.


A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases.

Li R, Mittelstein D, Lee J, Fang K, Majumdar R, Tintut Y, Demer LL, Hsiai TK.

Am J Physiol Cell Physiol. 2012 Feb 15;302(4):C658-65. doi: 10.1152/ajpcell.00313.2011. Epub 2011 Oct 26.


Adverse effects of hyperlipidemia on bone regeneration and strength.

Pirih F, Lu J, Ye F, Bezouglaia O, Atti E, Ascenzi MG, Tetradis S, Demer L, Aghaloo T, Tintut Y.

J Bone Miner Res. 2012 Feb;27(2):309-18. doi: 10.1002/jbmr.541.


Role of cellular cholesterol metabolism in vascular cell calcification.

Geng Y, Hsu JJ, Lu J, Ting TC, Miyazaki M, Demer LL, Tintut Y.

J Biol Chem. 2011 Sep 23;286(38):33701-6. doi: 10.1074/jbc.M111.269639. Epub 2011 Aug 11.


The roles of lipid oxidation products and receptor activator of nuclear factor-κB signaling in atherosclerotic calcification.

Demer L, Tintut Y.

Circ Res. 2011 Jun 10;108(12):1482-93. doi: 10.1161/CIRCRESAHA.110.234245. Review.


Hyperlipidemia induces resistance to PTH bone anabolism in mice via oxidized lipids.

Sage AP, Lu J, Atti E, Tetradis S, Ascenzi MG, Adams DJ, Demer LL, Tintut Y.

J Bone Miner Res. 2011 Jun;26(6):1197-206. doi: 10.1002/jbmr.312.


Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells.

Ting TC, Miyazaki-Anzai S, Masuda M, Levi M, Demer LL, Tintut Y, Miyazaki M.

J Biol Chem. 2011 Jul 8;286(27):23938-49. doi: 10.1074/jbc.M111.237065. Epub 2011 May 19.


The hemosteoblast: friend or foe?

Tintut Y, Demer L.

Circ Res. 2011 Apr 29;108(9):1038-9. doi: 10.1161/CIRCRESAHA.111.244665. No abstract available.


Runx2-upregulated receptor activator of nuclear factor κB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages.

Byon CH, Sun Y, Chen J, Yuan K, Mao X, Heath JM, Anderson PG, Tintut Y, Demer LL, Wang D, Chen Y.

Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1387-96. doi: 10.1161/ATVBAHA.110.222547. Epub 2011 Mar 31.


Hyperphosphatemia-induced nanocrystals upregulate the expression of bone morphogenetic protein-2 and osteopontin genes in mouse smooth muscle cells in vitro.

Sage AP, Lu J, Tintut Y, Demer LL.

Kidney Int. 2011 Feb;79(4):414-22. doi: 10.1038/ki.2010.390. Epub 2010 Oct 13.


Regulatory mechanisms in vascular calcification.

Sage AP, Tintut Y, Demer LL.

Nat Rev Cardiol. 2010 Sep;7(9):528-36. doi: 10.1038/nrcardio.2010.115. Epub 2010 Jul 27. Review.


PKA-induced receptor activator of NF-kappaB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification.

Tseng W, Graham LS, Geng Y, Reddy A, Lu J, Effros RB, Demer L, Tintut Y.

J Biol Chem. 2010 Sep 24;285(39):29925-31. doi: 10.1074/jbc.M110.117366. Epub 2010 Jul 27.


Bone density and hyperlipidemia: the T-lymphocyte connection.

Graham LS, Tintut Y, Parhami F, Kitchen CM, Ivanov Y, Tetradis S, Effros RB.

J Bone Miner Res. 2010 Nov;25(11):2460-9. doi: 10.1002/jbmr.148.


The bone-vascular axis in chronic kidney disease.

Demer L, Tintut Y.

Curr Opin Nephrol Hypertens. 2010 Jul;19(4):349-53. doi: 10.1097/MNH.0b013e32833a3d67. Review.


Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids.

Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y.

J Lipid Res. 2010 May;51(5):1010-6. doi: 10.1194/jlr.M001099. Epub 2009 Nov 11.


Systems biology of vascular calcification.

Sage A, Tintut Y, Garfinkel A, Demer L.

Trends Cardiovasc Med. 2009 May;19(4):118-23. doi: 10.1016/j.tcm.2009.07.002. Review.


Oxidized lipids enhance RANKL production by T lymphocytes: implications for lipid-induced bone loss.

Graham LS, Parhami F, Tintut Y, Kitchen CM, Demer LL, Effros RB.

Clin Immunol. 2009 Nov;133(2):265-75. doi: 10.1016/j.clim.2009.07.011. Epub 2009 Aug 22.


Mechanisms linking osteoporosis with cardiovascular calcification.

Demer LL, Tintut Y.

Curr Osteoporos Rep. 2009 Jul;7(2):42-6.


Mechanical stress analysis of a rigid inclusion in distensible material: a model of atherosclerotic calcification and plaque vulnerability.

Hoshino T, Chow LA, Hsu JJ, Perlowski AA, Abedin M, Tobis J, Tintut Y, Mal AK, Klug WS, Demer LL.

Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H802-10. doi: 10.1152/ajpheart.00318.2009. Epub 2009 Jun 19.

Supplemental Content

Loading ...
Support Center