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Items: 11


Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways.

Li J, Zhao Y, Coleman P, Chen J, Ting KK, Choi JP, Zheng X, Vadas MA, Gamble JR.

Biochim Biophys Acta Mol Basis Dis. 2019 Jul 29;1865(11):165519. doi: 10.1016/j.bbadis.2019.07.013. [Epub ahead of print]


ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis.

Lay AJ, Coleman PR, Formaz-Preston A, Ting KK, Roediger B, Weninger W, Schwartz MA, Vadas MA, Gamble JR.

J Am Heart Assoc. 2019 Jan 22;8(2):e010057. doi: 10.1161/JAHA.118.010057.


Therapeutic regulation of VE-cadherin with a novel oligonucleotide drug for diabetic eye complications using retinopathy mouse models.

Ting KK, Zhao Y, Shen W, Coleman P, Yam M, Chan-Ling T, Li J, Moller T, Gillies M, Vadas MA, Gamble JR.

Diabetologia. 2019 Feb;62(2):322-334. doi: 10.1007/s00125-018-4770-4. Epub 2018 Nov 15.


Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations.

Choi JP, Wang R, Yang X, Wang X, Wang L, Ting KK, Foley M, Cogger V, Yang Z, Liu F, Han Z, Liu R, Baell J, Zheng X.

Sci Adv. 2018 Nov 7;4(11):eaau0731. doi: 10.1126/sciadv.aau0731. eCollection 2018 Nov.


ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype.

Liu R, Lo L, Lay AJ, Zhao Y, Ting KK, Robertson EN, Sherrah AG, Jarrah S, Li H, Zhou Z, Hambly BD, Richmond DR, Jeremy RW, Bannon PG, Vadas MA, Gamble JR.

Circ Res. 2017 Aug 18;121(5):512-524. doi: 10.1161/CIRCRESAHA.117.310692. Epub 2017 Jul 12.


Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy.

Zhao Y, Ting KK, Li J, Cogger VC, Chen J, Johansson-Percival A, Ngiow SF, Holst J, Grau G, Goel S, Muller T, Dejana E, McCaughan G, Smyth MJ, Ganss R, Vadas MA, Gamble JR.

Cancer Res. 2017 Aug 15;77(16):4434-4447. doi: 10.1158/0008-5472.CAN-16-3129. Epub 2017 Jun 27. Erratum in: Cancer Res. 2018 Oct 1;78(19):5718.


ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions.

Chang GH, Lay AJ, Ting KK, Zhao Y, Coleman PR, Powter EE, Formaz-Preston A, Jolly CJ, Bower NI, Hogan BM, Rinkwitz S, Becker TS, Vadas MA, Gamble JR.

Small GTPases. 2014;5(3):1-15. doi: 10.4161/21541248.2014.975002.


Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27.

Young JA, Ting KK, Li J, Moller T, Dunn L, Lu Y, Moses J, Prado-Lourenço L, Khachigian LM, Ng M, Gregory PA, Goodall GJ, Tsykin A, Lichtenstein I, Hahn CN, Tran N, Shackel N, Kench JG, McCaughan G, Vadas MA, Gamble JR.

Blood. 2013 Oct 17;122(16):2911-9. doi: 10.1182/blood-2012-12-473017. Epub 2013 Sep 5. Erratum in: Blood. 2014 Nov 6;124(19):3034.


Characterisation of the expression of NMDA receptors in human astrocytes.

Lee MC, Ting KK, Adams S, Brew BJ, Chung R, Guillemin GJ.

PLoS One. 2010 Nov 30;5(11):e14123. doi: 10.1371/journal.pone.0014123.


Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease.

Ting KK, Brew BJ, Guillemin GJ.

J Neuroinflammation. 2009 Dec 10;6:36. doi: 10.1186/1742-2094-6-36.


The involvement of astrocytes and kynurenine pathway in Alzheimer's disease.

Ting KK, Brew B, Guillemin G.

Neurotox Res. 2007 Dec;12(4):247-62. Review.


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