Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 49

1.

Design of Disruptors of the Hsp90-Cdc37 Interface.

D'Annessa I, Hurwitz N, Pirota V, Beretta GL, Tinelli S, Woodford M, Freccero M, Mollapour M, Zaffaroni N, Wolfson H, Colombo G.

Molecules. 2020 Jan 15;25(2). pii: E360. doi: 10.3390/molecules25020360.

2.

miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition.

El Bezawy R, Tinelli S, Tortoreto M, Doldi V, Zuco V, Folini M, Stucchi C, Rancati T, Valdagni R, Gandellini P, Zaffaroni N.

J Exp Clin Cancer Res. 2019 Feb 4;38(1):51. doi: 10.1186/s13046-019-1060-z.

3.

Redox-Sensitive PEG-Polypeptide Nanoporous Particles for Survivin Silencing in Prostate Cancer Cells.

Cavalieri F, Beretta GL, Cui J, Braunger JA, Yan Y, Richardson JJ, Tinelli S, Folini M, Zaffaroni N, Caruso F.

Biomacromolecules. 2015 Jul 13;16(7):2168-78. doi: 10.1021/acs.biomac.5b00562. Epub 2015 Jun 29.

PMID:
26120930
4.

Unravelling "off-target" effects of redox-active polymers and polymer multilayered capsules in prostate cancer cells.

Beretta GL, Folini M, Cavalieri F, Yan Y, Fresch E, Kaliappan S, Hasenöhrl C, Richardson JJ, Tinelli S, Fery A, Caruso F, Zaffaroni N.

Nanoscale. 2015 Apr 14;7(14):6261-70. doi: 10.1039/c4nr07240e.

PMID:
25779724
5.

Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment.

Gatti L, Cossa G, Tinelli S, Carenini N, Arrighetti N, Pennati M, Cominetti D, De Cesare M, Zunino F, Zaffaroni N, Perego P.

J Pharmacol Exp Ther. 2014 Mar;348(3):360-71. doi: 10.1124/jpet.113.210054. Epub 2013 Dec 17.

PMID:
24345465
6.

Design, modeling, synthesis and biological activity evaluation of camptothecin-linked platinum anticancer agents.

Cincinelli R, Musso L, Dallavalle S, Artali R, Tinelli S, Colangelo D, Zunino F, De Cesare M, Beretta GL, Zaffaroni N.

Eur J Med Chem. 2013 May;63:387-400. doi: 10.1016/j.ejmech.2013.02.022. Epub 2013 Mar 1.

7.

[Heart failure: epidemiology, costs and healthcare programs in Italy].

Marangoni E, Lissoni F, Raimondi Cominesi I, Tinelli S.

G Ital Cardiol (Rome). 2012 Oct;13(10 Suppl 2):139S-144S. doi: 10.1714/1167.12938. Italian.

PMID:
23096393
8.

Bullying behaviours among students in Pavia, Italy: prevalence and association with stress and cannabis use.

Martinelli V, Brondino N, Rossi S, Panigati R, Magnani R, Cappucciati M, Vecchia L, Tinelli S, Emanuele E, Politi P.

Epidemiol Psychiatr Sci. 2011 Dec;20(4):339-43.

PMID:
22201211
9.

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

Perego P, Cossa G, Tinelli S, Corna E, Carenini N, Gatti L, De Cesare M, Ciusani E, Zunino F, Luison E, Canevari S, Zaffaroni N, Beretta GL.

Biochem Pharmacol. 2012 Jan 1;83(1):27-36. doi: 10.1016/j.bcp.2011.09.021. Epub 2011 Sep 29.

PMID:
21978643
10.

Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides.

Ferri N, Radice T, Antonino M, Beccalli EM, Tinelli S, Zunino F, Corsini A, Pratesi G, Ragg EM, Gelmi ML, Contini A.

Bioorg Med Chem. 2011 Sep 15;19(18):5291-9. doi: 10.1016/j.bmc.2011.08.016. Epub 2011 Aug 16.

PMID:
21880496
11.

Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards.

Pizzamiglio S, Cossa G, Gatti L, Beretta GL, Corna E, Tinelli S, Verderio P, Perego P.

Oncol Rep. 2010 Mar;23(3):853-60.

PMID:
20127029
12.

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment.

Bertolini G, Roz L, Perego P, Tortoreto M, Fontanella E, Gatti L, Pratesi G, Fabbri A, Andriani F, Tinelli S, Roz E, Caserini R, Lo Vullo S, Camerini T, Mariani L, Delia D, Calabrò E, Pastorino U, Sozzi G.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16281-6. doi: 10.1073/pnas.0905653106. Epub 2009 Sep 10.

13.

Semisynthesis, biological activity, and molecular modeling studies of C-ring-modified camptothecins.

Samorì C, Guerrini A, Varchi G, Fontana G, Bombardelli E, Tinelli S, Beretta GL, Basili S, Moro S, Zunino F, Battaglia A.

J Med Chem. 2009 Feb 26;52(4):1029-39. doi: 10.1021/jm801153y.

PMID:
19530720
14.

Interaction between double helix DNA fragments and a new topopyrone acting as human topoisomerase I poison.

Scaglioni L, Mazzini S, Mondelli R, Dallavalle S, Gattinoni S, Tinelli S, Beretta GL, Zunino F, Ragg E.

Bioorg Med Chem. 2009 Jan 15;17(2):484-91. doi: 10.1016/j.bmc.2008.12.005. Epub 2008 Dec 10.

PMID:
19097800
15.

Synthesis and cytotoxic activity of new 9-substituted camptothecins.

Dallavalle S, Rocchetta DG, Musso L, Merlini L, Morini G, Penco S, Tinelli S, Beretta GL, Zunino F.

Bioorg Med Chem Lett. 2008 May 1;18(9):2781-7. doi: 10.1016/j.bmcl.2008.04.016. Epub 2008 Apr 10.

PMID:
18434153
16.

The human homolog of fission yeast Rad17 is implicated in tumor growth.

Beretta GL, Gatti L, Cesare MD, Corna E, Tinelli S, Carenini N, Zunino F, Perego P.

Cancer Lett. 2008 Aug 8;266(2):194-202. doi: 10.1016/j.canlet.2008.02.057. Epub 2008 Apr 18.

PMID:
18378394
17.

Modulation of survival pathways in ovarian carcinoma cell lines resistant to platinum compounds.

Benedetti V, Perego P, Luca Beretta G, Corna E, Tinelli S, Righetti SC, Leone R, Apostoli P, Lanzi C, Zunino F.

Mol Cancer Ther. 2008 Mar;7(3):679-87. doi: 10.1158/1535-7163.MCT-07-0450.

18.

Synthesis and cytotoxic activity of a new series of topoisomerase I inhibitors.

Dallavalle S, Gattinoni S, Mazzini S, Scaglioni L, Merlini L, Tinelli S, Beretta GL, Zunino F.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1484-9. doi: 10.1016/j.bmcl.2007.12.055. Epub 2007 Dec 25.

PMID:
18248813
19.

Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3-heteroarylmaleimides and heterofused imides.

Ferri N, Beccalli EM, Contini A, Corsini A, Antonino M, Radice T, Pratesi G, Tinelli S, Zunino F, Gelmi ML.

Bioorg Med Chem. 2008 Feb 15;16(4):1691-701. Epub 2007 Nov 13.

PMID:
18061459
20.

Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus.

Clericuzio M, Tabasso S, Bianco MA, Pratesi G, Beretta G, Tinelli S, Zunino F, Vidari G.

J Nat Prod. 2006 Dec;69(12):1796-9.

PMID:
17190463
21.

Preclinical efficacy of ST1976, a novel camptothecin analog of the 7-oxyiminomethyl series.

De Cesare M, Beretta GL, Tinelli S, Benedetti V, Pratesi G, Penco S, Dallavalle S, Merlini L, Pisano C, Carminati P, Zunino F.

Biochem Pharmacol. 2007 Mar 1;73(5):656-64. Epub 2006 Nov 9.

PMID:
17169332
22.

Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.

Beretta GL, Petrangolini G, De Cesare M, Pratesi G, Perego P, Tinelli S, Tortoreto M, Zucchetti M, Frapolli R, Bello E, Manzotti C, Fontana G, Bombardelli E, Battaglia A, Samorì C, Zunino F.

Cancer Res. 2006 Nov 15;66(22):10976-82.

23.

Synthesis and cytotoxic activity of polyamine analogues of camptothecin.

Dallavalle S, Giannini G, Alloatti D, Casati A, Marastoni E, Musso L, Merlini L, Morini G, Penco S, Pisano C, Tinelli S, De Cesare M, Beretta GL, Zunino F.

J Med Chem. 2006 Aug 24;49(17):5177-86.

PMID:
16913706
24.

Synthesis and cytotoxic activity of substituted luotonin A derivatives.

Dallavalle S, Merlini L, Beretta GL, Tinelli S, Zunino F.

Bioorg Med Chem Lett. 2004 Dec 6;14(23):5757-61.

PMID:
15501036
25.

Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells.

Beretta GL, Gatti L, Tinelli S, Corna E, Colangelo D, Zunino F, Perego P.

Biochem Pharmacol. 2004 Jul 15;68(2):283-91.

PMID:
15194000
26.

Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin.

Dallavalle S, Merlini L, Morini G, Musso L, Penco S, Beretta GL, Tinelli S, Zunino F.

Eur J Med Chem. 2004 Jun;39(6):507-13.

PMID:
15183909
27.

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

Perego P, Gatti L, Righetti SC, Beretta GL, Carenini N, Corna E, Dal Bo L, Tinelli S, Colangelo D, Leone R, Apostoli P, Lombardi L, Beggiolin G, Piazzoni L, Zunino F.

Int J Cancer. 2003 Jul 10;105(5):617-24.

28.

Potent antitumor activity and improved pharmacological profile of ST1481, a novel 7-substituted camptothecin.

De Cesare M, Pratesi G, Perego P, Carenini N, Tinelli S, Merlini L, Penco S, Pisano C, Bucci F, Vesci L, Pace S, Capocasa F, Carminati P, Zunino F.

Cancer Res. 2001 Oct 1;61(19):7189-95.

29.

Directed evolution to increase camptothecin sensitivity of human DNA topoisomerase I.

Scaldaferro S, Tinelli S, Borgnetto ME, Azzini A, Capranico G.

Chem Biol. 2001 Sep;8(9):871-81.

30.

Topoisomerase poisoning activity of novel disaccharide anthracyclines.

Guano F, Pourquier P, Tinelli S, Binaschi M, Bigioni M, Animati F, Manzini S, Zunino F, Kohlhagen G, Pommier Y, Capranico G.

Mol Pharmacol. 1999 Jul;56(1):77-84.

PMID:
10385686
31.

Genomic sites of topoisomerase II activity determined by comparing DNA breakage enhanced by three distinct poisons.

Borgnetto ME, Tinelli S, Carminati L, Capranico G.

J Mol Biol. 1999 Jan 15;285(2):545-54.

PMID:
9878428
32.

Amsacrine-promoted DNA cleavage site determinants for the two human DNA topoisomerase II isoforms alpha and beta.

Marsh KL, Willmore E, Tinelli S, Cornarotti M, Meczes EL, Capranico G, Fisher LM, Austin CA.

Biochem Pharmacol. 1996 Dec 13;52(11):1675-85.

PMID:
8986129
33.

Drug sensitivity and sequence specificity of human recombinant DNA topoisomerases IIalpha (p170) and IIbeta (p180).

Cornarotti M, Tinelli S, Willmore E, Zunino F, Fisher LM, Austin CA, Capranico G.

Mol Pharmacol. 1996 Dec;50(6):1463-71.

PMID:
8967966
34.

Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: heterogeneous localization and reversibility.

Borgnetto ME, Zunino F, Tinelli S, Kas E, Capranico G.

Cancer Res. 1996 Apr 15;56(8):1855-62.

35.

Position-specific effects of base mismatch on mammalian topoisomerase II DNA cleaving activity.

Bigioni M, Zunino F, Tinelli S, Austin CA, Willmore E, Capranico G.

Biochemistry. 1996 Jan 9;35(1):153-9.

PMID:
8555169
36.

Unique sequence specificity of topoisomerase II DNA cleavage stimulation and DNA binding mode of streptonigrin.

Capranico G, Palumbo M, Tinelli S, Zunino F.

J Biol Chem. 1994 Oct 7;269(40):25004-9.

37.

Conformational properties of topoisomerase II inhibitors and sequence specificity of DNA cleavage.

Palumbo M, Mabilia M, Pozzan A, Capranico G, Tinelli S, Zunino F.

J Mol Recognit. 1994 Sep;7(3):227-31.

PMID:
7880548
38.

Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage.

Capranico G, Palumbo M, Tinelli S, Mabilia M, Pozzan A, Zunino F.

J Mol Biol. 1994 Jan 28;235(4):1218-30.

PMID:
8308885
39.

Similar sequence specificity of mitoxantrone and VM-26 stimulation of in vitro DNA cleavage by mammalian DNA topoisomerase II.

Capranico G, De Isabella P, Tinelli S, Bigioni M, Zunino F.

Biochemistry. 1993 Mar 30;32(12):3038-46.

PMID:
8384486
40.

Effects of base mutations on topoisomerase II DNA cleavage stimulated by mAMSA in short DNA oligomers.

Capranico G, Tinelli S, Zunino F, Kohn KW, Pommier Y.

Biochemistry. 1993 Jan 12;32(1):145-52.

PMID:
8380330
41.

Different patterns of gene expression of topoisomerase II isoforms in differentiated tissues during murine development.

Capranico G, Tinelli S, Austin CA, Fisher ML, Zunino F.

Biochim Biophys Acta. 1992 Aug 17;1132(1):43-8.

PMID:
1380833
42.

Comparison of DNA cleavage induced by etoposide and doxorubicin in two human small-cell lung cancer lines with different sensitivities to topoisomerase II inhibitors.

Binaschi M, Capranico G, De Isabella P, Mariani M, Supino R, Tinelli S, Zunino F.

Int J Cancer. 1990 Feb 15;45(2):347-52.

PMID:
2154411
43.

Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells.

De Isabella P, Capranico G, Binaschi M, Tinelli S, Zunino F.

Mol Pharmacol. 1990 Jan;37(1):11-6.

PMID:
2153905
44.
45.

Formation, resealing and persistence of DNA breaks produced by 4-demethoxydaunorubicin in P388 leukemia cells.

Capranico G, Tinelli S, Zunino F.

Chem Biol Interact. 1989;72(1-2):113-23.

PMID:
2555070
46.

Markedly reduced levels of anthracycline-induced DNA strand breaks in resistant P388 leukemia cells and isolated nuclei.

Capranico G, Riva A, Tinelli S, Dasdia T, Zunino F.

Cancer Res. 1987 Jul 15;47(14):3752-6.

47.

Poly-L-aspartic acid as a carrier for doxorubicin: a comparative in vivo study of free and polymer-bound drug.

Pratesi G, Savi G, Pezzoni G, Bellini O, Penco S, Tinelli S, Zunino F.

Br J Cancer. 1985 Dec;52(6):841-8.

48.

Comparison of antitumor effects of daunorubicin covalently linked to poly-L-amino acid carriers.

Zunino F, Savi G, Giuliani F, Gambetta R, Supino R, Tinelli S, Pezzoni G.

Eur J Cancer Clin Oncol. 1984 Mar;20(3):421-5.

PMID:
6538501
49.

The relationship of family concept to individual self-esteem.

Tinelli SO.

Issues Ment Health Nurs. 1981 Jul-Sep;3(3):251-70. No abstract available.

PMID:
6913556

Supplemental Content

Loading ...
Support Center