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Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis.

Van Wyngene L, Vanderhaeghen T, Timmermans S, Vandewalle J, Van Looveren K, Souffriau J, Wallaeys C, Eggermont M, Ernst S, Van Hamme E, Gonçalves A, Eelen G, Remmerie A, Scott CL, Rombouts C, Vanhaecke L, De Bus L, Decruyenaere J, Carmeliet P, Libert C.

EMBO Mol Med. 2020 Jan 9:e11319. doi: 10.15252/emmm.201911319. [Epub ahead of print]


'It is not entirely healthy.' A qualitative study into public appraisals of uncertain risks of chemical substances in food.

Jansen T, Claassen L, van Kamp I, Timmermans DR.

Public Underst Sci. 2020 Jan 9:963662519897574. doi: 10.1177/0963662519897574. [Epub ahead of print]


Impact of erythrocyte long-chain omega-3 polyunsaturated fatty acid levels in early pregnancy on birth outcomes: findings from a Belgian cohort study.

Hoge A, Donneau AF, Dardenne N, Degée S, Timmermans M, Nisolle M, Guillaume M, Castronovo V.

J Perinatol. 2020 Jan 8. doi: 10.1038/s41372-019-0573-9. [Epub ahead of print]


Tunable room-temperature spin galvanic and spin Hall effects in van der Waals heterostructures.

Benítez LA, Savero Torres W, Sierra JF, Timmermans M, Garcia JH, Roche S, Costache MV, Valenzuela SO.

Nat Mater. 2020 Jan 6. doi: 10.1038/s41563-019-0575-1. [Epub ahead of print]


'An insight into circumcised men seeking foreskin reconstruction: a prospective cohort study'.

Özer M, Timmermans FW.

Int J Impot Res. 2020 Jan 2. doi: 10.1038/s41443-019-0223-y. [Epub ahead of print]


Macroalgae Derived Fungi Have High Abilities to Degrade Algal Polymers.

Patyshakuliyeva A, Falkoski DL, Wiebenga A, Timmermans K, Vries RP.

Microorganisms. 2019 Dec 26;8(1). pii: E52. doi: 10.3390/microorganisms8010052.


Reversibility of membrane permeabilization upon pulsed electric field treatment in Lactobacillus plantarum WCFS1.

Vaessen EMJ, Timmermans RAH, Tempelaars MH, Schutyser MAI, den Besten HMW.

Sci Rep. 2019 Dec 27;9(1):19990. doi: 10.1038/s41598-019-56299-w.


Dual-responsive "smart" window and visually attractive coating based on a diarylethene photochromic dye.

Timmermans GH, Saes BWH, Debije MG.

Appl Opt. 2019 Dec 20;58(36):9823-9828. doi: 10.1364/AO.58.009823.


Inequities in newborn screening: Race and the role of medicaid.

Sohn H, Timmermans S.

SSM Popul Health. 2019 Oct 7;9:100496. doi: 10.1016/j.ssmph.2019.100496. eCollection 2019 Dec.


Diagnostic and Risk Factors for Complement Defects in Hypertensive Emergency and Thrombotic Microangiopathy.

Timmermans SAMEG, Wérion A, Damoiseaux JGMC, Morelle J, Reutelingsperger CP, van Paassen P.

Hypertension. 2020 Feb;75(2):422-430. doi: 10.1161/HYPERTENSIONAHA.119.13714. Epub 2019 Dec 23.


Latitudinal variation in seed predation correlates with latitudinal variation in seed defensive and nutritional traits in a widespread oak species.

Moreira X, Abdala-Roberts L, Bruun HH, Covelo F, Frenne P, Galmán A, Gaytán Á, Jaatinen R, Pulkkinen P, Ten Hoopen JPJG, Timmermans BGH, Tack AJM, Castagneyrol B.

Ann Bot. 2019 Dec 20. pii: mcz207. doi: 10.1093/aob/mcz207. [Epub ahead of print]


Reintervention after aortic valve replacement: Comparison of three aortic bioprostheses.

Lam KY, Koene B, Timmermans N, Soliman-Hamad M, van Straten A.

Ann Thorac Surg. 2019 Dec 14. pii: S0003-4975(19)31874-0. doi: 10.1016/j.athoracsur.2019.10.060. [Epub ahead of print]


The use of PROMs and shared decision-making in medical encounters with patients: An opportunity to deliver value-based health care to patients.

Damman OC, Jani A, de Jong BA, Becker A, Metz MJ, de Bruijne MC, Timmermans DR, Cornel MC, Ubbink DT, van der Steen M, Gray M, van El C.

J Eval Clin Pract. 2019 Dec 15. doi: 10.1111/jep.13321. [Epub ahead of print]


Progression of incomplete toward complete left bundle branch block: A clinical and electrocardiographic analysis.

Senesael E, Calle S, Kamoen V, Stroobandt R, De Buyzere M, Timmermans F, De Pooter J.

Ann Noninvasive Electrocardiol. 2019 Dec 11:e12732. doi: 10.1111/anec.12732. [Epub ahead of print]


Developing an intelligent activity-based client-centred training system with a user-centred approach.

Knippenberg E, Van Hout L, Smeets W, Palmaers S, Timmermans A, Spooren A.

Technol Health Care. 2019 Nov 22. doi: 10.3233/THC-191854. [Epub ahead of print]


Unearthing Hidden Chemical Potential from Discarded Actinobacterial Libraries.

Timmermans ML, Ross AC.

Trends Biotechnol. 2020 Jan;38(1):7-9. doi: 10.1016/j.tibtech.2019.11.003. Epub 2019 Nov 27.


European reference network for rare vascular diseases (VASCERN) consensus statement for the screening and management of patients with pathogenic ACTA2 variants.

van de Laar IMBH, Arbustini E, Loeys B, Björck E, Murphy L, Groenink M, Kempers M, Timmermans J, Roos-Hesselink J, Benke K, Pepe G, Mulder B, Szabolcs Z, Teixidó-Turà G, Robert L, Emmanuel Y, Evangelista A, Pini A, von Kodolitsch Y, Jondeau G, De Backer J.

Orphanet J Rare Dis. 2019 Nov 21;14(1):264. doi: 10.1186/s13023-019-1186-2.


The impact of interpregnancy weight change on perinatal outcomes in women and their children: A systematic review and meta-analysis.

Timmermans YEG, van de Kant KDG, Oosterman EO, Spaanderman MEA, Villamor-Martinez E, Kleijnen J, Vreugdenhil ACE.

Obes Rev. 2019 Nov 21. doi: 10.1111/obr.12974. [Epub ahead of print] Review.


Effects of intestinal alkaline phosphatase on intestinal barrier function in a cecal ligation and puncture (CLP)-induced mouse model for sepsis.

Plaeke P, De Man JG, Smet A, Malhotra-Kumar S, Pintelon I, Timmermans JP, Nullens S, Jorens PG, Hubens G, De Winter BY.

Neurogastroenterol Motil. 2019 Nov 21:e13754. doi: 10.1111/nmo.13754. [Epub ahead of print]


Towards Prepared mums (TOP-mums) for a healthy start, a lifestyle intervention for women with overweight and a child wish: study protocol for a randomised controlled trial in the Netherlands.

Timmermans YEG, van de Kant KDG, Reijnders D, Kleijkers LMP, Dompeling E, Kramer BW, Zimmermann LJI, Steegers-Theunissen RPM, Spaanderman MEA, Vreugdenhil ACE.

BMJ Open. 2019 Nov 19;9(11):e030236. doi: 10.1136/bmjopen-2019-030236.


Cardiac remodeling in obesity and after bariatric and metabolic surgery; is there a role for gastro-intestinal hormones?

Sanches E, Timmermans M, Topal B, Celik A, Sundbom M, Ribeiro R, Parmar C, Ugale S, Proczko M, Stepaniak PS, Pujol Rafols J, Mahawar K, Buise MP, Neimark A, Severin R, Pouwels S.

Expert Rev Cardiovasc Ther. 2019 Nov;17(11):771-790. doi: 10.1080/14779072.2019.1690991. Epub 2019 Nov 20.


A high-resolution gene expression atlas links dedicated meristem genes to key architectural traits.

Knauer S, Javelle M, Li L, Li X, Ma X, Wimalanathan K, Kumari S, Johnston R, Leiboff S, Meeley R, Schnable PS, Ware D, Lawrence-Dill C, Yu J, Muehlbauer GJ, Scanlon MJ, Timmermans MCP.

Genome Res. 2019 Dec;29(12):1962-1973. doi: 10.1101/gr.250878.119. Epub 2019 Nov 19.


Factors impacting attrition of vulnerable women from a longitudinal mental health intervention study.

Molewyk Doornbos M, Zandee GL, Timmermans B, Moes J, Heitsch E, Quist M, Heetderks E, Houskamp C, VanWolde A.

Public Health Nurs. 2020 Jan;37(1):73-80. doi: 10.1111/phn.12687. Epub 2019 Nov 17.


'All chemical substances are harmful.' public appraisal of uncertain risks of food additives and contaminants.

Jansen T, Claassen L, van Kamp I, Timmermans DRM.

Food Chem Toxicol. 2020 Feb;136:110959. doi: 10.1016/j.fct.2019.110959. Epub 2019 Nov 13.


Glucocorticoid and β-adrenergic regulation of hippocampal dendritic spines.

Lesuis SL, Timmermans W, Lucassen PJ, Hoogenraad CC, Krugers HJ.

J Neuroendocrinol. 2020 Jan;32(1):e12811. doi: 10.1111/jne.12811. Epub 2019 Dec 5.


Optimizing Survival Predictions of Hypopharynx Cancer: Development of a Clinical Prediction Model.

Arends CR, Petersen JF, van der Noort V, Timmermans AJ, Leemans CR, de Bree R, van den Brekel MWM, Stuiver MM.

Laryngoscope. 2019 Nov 6. doi: 10.1002/lary.28345. [Epub ahead of print]


Progressive Pulmonary Artery Dilatation is Associated with Type B Aortic Dissection in Patients with Marfan Syndrome.

Brouwer C, Bulut H, van Gemert W, Staal AH, Cortenbach K, Snoeren M, Nijveldt R, Duijnhouwer A, Loeys BL, van Royen N, Timmermans J, van Kimmenade RR.

J Clin Med. 2019 Nov 2;8(11). pii: E1848. doi: 10.3390/jcm8111848.


Associations of neighbourhood safety with leisure-time walking and cycling in population subgroups: The HELIUS study.

Timmermans EJ, Veldhuizen EM, Mäki-Opas T, Snijder MB, Lakerveld J, Kunst AE.

Spat Spatiotemporal Epidemiol. 2019 Nov;31:100300. doi: 10.1016/j.sste.2019.100300. Epub 2019 Aug 7.


Development of a decision support tool in pediatric Differences/Disorders of Sex Development.

Sandberg DE, Gardner M, Kopec K, Urbanski M, Callens N, Keegan CE, Yashar BM, Fechner PY, Shnorhavorian M, Vilain E, Timmermans S, Siminoff LA.

Semin Pediatr Surg. 2019 Oct;28(5):150838. doi: 10.1016/j.sempedsurg.2019.150838. Epub 2019 Sep 13.


Ascertainment of cancer in longitudinal research: The concordance between the Rotterdam Study and the Netherlands Cancer Registry.

van der Willik KD, Ruiter R, van Rooij FJA, Verkroost-van Heemst J, Hogewoning SJ, Timmermans KCAA, Visser O, Schagen SB, Ikram MA, Stricker BHC.

Int J Cancer. 2019 Oct 23. doi: 10.1002/ijc.32750. [Epub ahead of print]


The Average Pixel Intensity Method and Outcome of Mitral Regurgitation in Mitral Valve Prolapse.

Kamoen V, El Haddad M, De Backer T, De Buyzere M, Timmermans F.

J Am Soc Echocardiogr. 2020 Jan;33(1):54-63. doi: 10.1016/j.echo.2019.07.021. Epub 2019 Oct 13.


Evaluation of Information in Summaries of Product Characteristics (SmPCs) on the Use of a Medicine in Patients With Hepatic Impairment.

Weersink RA, Timmermans L, Monster-Simons MH, Mol PGM, Metselaar HJ, Borgsteede SD, Taxis K.

Front Pharmacol. 2019 Sep 17;10:1031. doi: 10.3389/fphar.2019.01031. eCollection 2019.


Cosmetic Injection of Botulinum Toxin Unmasking Subclinical Myasthenia Gravis: A Case Report and Literature Review.

Timmermans G, Depierreux F, Wang F, Hansen I, Maquet P.

Case Rep Neurol. 2019 Aug 16;11(2):244-251. doi: 10.1159/000502350. eCollection 2019 May-Aug.


Intensive Livestock Farming and Residential Health: Experts' Views.

Eijrond V, Claassen L, van der Giessen J, Timmermans D.

Int J Environ Res Public Health. 2019 Sep 27;16(19). pii: E3625. doi: 10.3390/ijerph16193625.


Biopsy samples from the erector spinae of persons with nonspecific chronic low back pain display a decrease in glycolytic muscle fibers.

Agten A, Stevens S, Verbrugghe J, Timmermans A, Vandenabeele F.

Spine J. 2019 Sep 27. pii: S1529-9430(19)31019-8. doi: 10.1016/j.spinee.2019.09.023. [Epub ahead of print]


Rationale and design of the IRON-CRT trial: effect of intravenous ferric carboxymaltose on reverse remodelling following cardiac resynchronization therapy.

Martens P, Dupont M, Dauw J, Somers F, Herbots L, Timmermans P, Verwerft J, Mullens W.

ESC Heart Fail. 2019 Sep 28. doi: 10.1002/ehf2.12503. [Epub ahead of print]


Phylogenomics resolves major relationships and reveals significant diversification rate shifts in the evolution of silk moths and relatives.

Hamilton CA, St Laurent RA, Dexter K, Kitching IJ, Breinholt JW, Zwick A, Timmermans MJTN, Barber JR, Kawahara AY.

BMC Evol Biol. 2019 Sep 18;19(1):182. doi: 10.1186/s12862-019-1505-1.


Changes of Metabolic Phenotype of Cardiac Progenitor Cells During Differentiation: Neutral Effect of Stimulation of AMP-Activated Protein Kinase.

André E, De Pauw A, Verdoy R, Brusa D, Bouzin C, Timmermans A, Bertrand L, Balligand JL.

Stem Cells Dev. 2019 Nov 15;28(22):1498-1513. doi: 10.1089/scd.2019.0129. Epub 2019 Oct 22.


Association Between Osteoarthritis and Social Isolation: Data From the EPOSA Study.

Siviero P, Veronese N, Smith T, Stubbs B, Limongi F, Zambon S, Dennison EM, Edwards M, Cooper C, Timmermans EJ, van Schoor NM, van der Pas S, Schaap LA, Denkinger MD, Peter R, Herbolsheimer F, Otero Á, Castell MV, Pedersen NL, Deeg DJH, Maggi S; EPOSA Research Group.

J Am Geriatr Soc. 2020 Jan;68(1):87-95. doi: 10.1111/jgs.16159. Epub 2019 Sep 17.


Mobius syndrome and obsessive compulsive disorder: a case report.

Jacque D, Ossemann M, Timmermans JM, Zdanowicz N, Dubois T.

Psychiatr Danub. 2019 Sep;31(Suppl 3):376-380.


Editorial: Trauma-Induced, DAMP-Mediated Remote Organ Injury, and Immunosuppression in the Acutely Ill Patient.

Pottecher J, Meyer A, Wenceslau CF, Timmermans K, Hauser CJ, Land WG.

Front Immunol. 2019 Aug 20;10:1971. doi: 10.3389/fimmu.2019.01971. eCollection 2019. No abstract available.


Presence of MrgprD within the gastrointestinal wall: reality or fake?

Van Remoortel S, Timmermans JP.

Cell Tissue Res. 2019 Dec;378(3):555-558. doi: 10.1007/s00441-019-03097-5. Epub 2019 Aug 31.


Motor response influences perceptual awareness judgements.

Siedlecka M, Hobot J, Skóra Z, Paulewicz B, Timmermans B, Wierzchoń M.

Conscious Cogn. 2019 Oct;75:102804. doi: 10.1016/j.concog.2019.102804. Epub 2019 Aug 19.


Associations of neighbourhood sociodemographic characteristics with depressive and anxiety symptoms in older age: Results from a 5-wave study over 15 years.

Motoc I, Timmermans EJ, Deeg D, Penninx BWJH, Huisman M.

Health Place. 2019 Sep;59:102172. doi: 10.1016/j.healthplace.2019.102172. Epub 2019 Aug 15.


Cardiac implantable electronic devices with a defibrillator component and all-cause mortality in left ventricular assist device carriers: results from the PCHF-VAD registry.

Cikes M, Jakus N, Claggett B, Brugts JJ, Timmermans P, Pouleur AC, Rubis P, Van Craenenbroeck EM, Gaizauskas E, Grundmann S, Paolillo S, Barge-Caballero E, D'Amario D, Gkouziouta A, Planinc I, Veenis JF, Jacquet LM, Houard L, Holcman K, Gigase A, Rega F, Rucinskas K, Adamopoulos S, Agostoni P, Biocina B, Gasparovic H, Lund LH, Flammer AJ, Metra M, Milicic D, Ruschitzka F; PCHF-VAD registry.

Eur J Heart Fail. 2019 Sep;21(9):1129-1141. doi: 10.1002/ejhf.1568. Epub 2019 Aug 13.


Perioperative change in CA125 is an independent prognostic factor for improved clinical outcome in advanced ovarian cancer.

Timmermans M, Zwakman N, Sonke GS, Van de Vijver KK, Duk MJ, van der Aa MA, Kruitwagen RF.

Eur J Obstet Gynecol Reprod Biol. 2019 Sep;240:364-369. doi: 10.1016/j.ejogrb.2019.07.010. Epub 2019 Jul 26.


Economic impact of contagious caprine pleuropneumonia and cost-benefit analysis of the vaccination programmes based on a one-year continuous monitoring of flocks in the arid and semi-arid lands of Kenya.

Renault V, Hambe HA, Van Vlaenderen G, Timmermans E, Mohamed AM, Ethgen O, Saegerman C.

Transbound Emerg Dis. 2019 Nov;66(6):2523-2536. doi: 10.1111/tbed.13317. Epub 2019 Aug 25.


Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs.

Choi J, Wagner LJS, Timmermans SBPE, Malaker SA, Schumann B, Gray MA, Debets MF, Takashima M, Gehring J, Bertozzi CR.

J Am Chem Soc. 2019 Aug 28;141(34):13442-13453. doi: 10.1021/jacs.9b04695. Epub 2019 Aug 16.


The Longitudinal Aging Study Amsterdam: cohort update 2019 and additional data collections.

Hoogendijk EO, Deeg DJH, de Breij S, Klokgieters SS, Kok AAL, Stringa N, Timmermans EJ, van Schoor NM, van Zutphen EM, van der Horst M, Poppelaars J, Malhoe P, Huisman M.

Eur J Epidemiol. 2019 Jul 25. doi: 10.1007/s10654-019-00541-2. [Epub ahead of print]


Chondroid metaplasia of paraspinal connective tissue in the degenerative spine.

Stevens S, Agten A, Wisanto E, Monaco ML, Verbrugghe J, Timmermans A, Lambrichts I, Vandenabeele F.

Anat Cell Biol. 2019 Jun;52(2):204-207. doi: 10.5115/acb.2019.52.2.204. Epub 2019 Jun 30.

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