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Items: 1 to 50 of 201

1.

A double armed, hydrophilic, transition metal complex as paramagnetic NMR probe.

Miao Q, Liu WM, Kock T, Blok A, Timmer M, Overhand M, Ubbink M.

Angew Chem Int Ed Engl. 2019 Jul 17. doi: 10.1002/anie.201906049. [Epub ahead of print]

PMID:
31314159
2.

The synthesis and evaluation of quinolinequinones as anti-mycobacterial agents.

Santoso KT, Menorca A, Cheung CY, Cook GM, Stocker BL, Timmer MSM.

Bioorg Med Chem. 2019 Jun 1. pii: S0968-0896(19)30689-3. doi: 10.1016/j.bmc.2019.06.002. [Epub ahead of print]

PMID:
31262663
3.

The expression of CD40 correlates negatively with overall- and progression free survival of low- and high-grade gliomas.

Werner JM, Kuhl S, Ulrich K, Krischek B, Stavrinou P, Goldbrunner R, Timmer M.

World Neurosurg. 2019 May 21. pii: S1878-8750(19)31386-5. doi: 10.1016/j.wneu.2019.05.112. [Epub ahead of print]

PMID:
31125770
4.

Death Receptor 6 (DR6) Is Overexpressed in Astrocytomas.

Stegmann S, Werner JM, Kuhl S, Röhn G, Krischek B, Stavrinou P, Goldbrunner R, Timmer M.

Anticancer Res. 2019 May;39(5):2299-2306. doi: 10.21873/anticanres.13346.

PMID:
31092421
5.

Impact of time to initiation of radiotherapy on survival after resection of newly diagnosed glioblastoma.

Katsigiannis S, Krischek B, Barleanu S, Grau S, Galldiks N, Timmer M, Kabbasch C, Goldbrunner R, Stavrinou P.

Radiat Oncol. 2019 Apr 29;14(1):73. doi: 10.1186/s13014-019-1272-6.

6.

Impact of aneurysm shape and neck configuration on cerebral infarction during microsurgical clipping of intracranial aneurysms.

Goertz L, Hamisch C, Kabbasch C, Borggrefe J, Hof M, Dempfle AK, Lenschow M, Stavrinou P, Timmer M, Brinker G, Goldbrunner R, Krischek B.

J Neurosurg. 2019 Apr 12:1-9. doi: 10.3171/2019.1.JNS183193. [Epub ahead of print]

PMID:
30978687
7.

Heterogeneity of Human Gliomas: Glutathione-S-Transferase Expression Profile During Disease Progression and Under Systemic Therapy.

Tjiong R, Stavrinou P, Röhn G, Krischek B, Koch A, Goldbrunner R, Timmer M.

Anticancer Res. 2019 Apr;39(4):1795-1805. doi: 10.21873/anticanres.13286.

PMID:
30952719
8.

Qualitative and Quantitative Analysis of IDH1 Mutation in Progressive Gliomas by Allele-Specific qPCR and Western Blot Analysis.

Perrech M, Dreher L, Röhn G, Stavrinou P, Krischek B, Toliat M, Goldbrunner R, Timmer M.

Technol Cancer Res Treat. 2019 Jan 1;18:1533033819828396. doi: 10.1177/1533033819828396.

9.

Vein Graft Interposition: A Training Model Using Gradually Thawed Cryopreserved Vessels.

Safi AF, Safi S, Tayeh M, Gojowy D, Timmer M, Goldbrunner R, Kauke M.

J Craniofac Surg. 2019 May/Jun;30(3):e213-e216. doi: 10.1097/SCS.0000000000005197.

PMID:
30845093
10.

MSU Crystals Enhance TDB-Mediated Inflammatory Macrophage IL-1β Secretion.

Wahi K, Kodar K, McConnell MJ, Harper JL, Timmer MSM, Stocker BL.

Inflammation. 2019 Jun;42(3):1129-1136. doi: 10.1007/s10753-019-00976-5.

PMID:
30806957
11.

Elective Treatment of Additional and Recurrent Aneurysms in Patients with a Previous Subarachnoid Hemorrhage: A Single-Center Analysis of Complications and Clinical Outcome.

Goertz L, Brinker G, Hamisch C, Kabbasch C, Borggrefe J, Hof M, Timmer M, Stavrinou P, Goldbrunner R, Krischek B.

World Neurosurg. 2019 Feb 19. pii: S1878-8750(19)30398-5. doi: 10.1016/j.wneu.2019.01.279. [Epub ahead of print]

PMID:
30794974
12.

Long-Term Outcome and Health-Related Quality of Life of Elderly Patients After Meningioma Surgery.

Timmer M, Seibl-Leven M, Wittenstein K, Grau S, Stavrinou P, Röhn G, Krischek B, Goldbrunner R.

World Neurosurg. 2019 Feb 5. pii: S1878-8750(19)30258-X. doi: 10.1016/j.wneu.2019.01.158. [Epub ahead of print]

PMID:
30735873
13.

Synthesis and Investigation of Phthalazinones as Antitubercular Agents.

Santoso KT, Cheung CY, Hards K, Cook GM, Stocker BL, Timmer MSM.

Chem Asian J. 2019 Apr 15;14(8):1278-1285. doi: 10.1002/asia.201801805. Epub 2019 Feb 13.

PMID:
30680937
14.

A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications.

Gobin M, Nazarov PV, Warta R, Timmer M, Reifenberger G, Felsberg J, Vallar L, Chalmers AJ, Herold-Mende CC, Goldbrunner R, Niclou SP, Van Dyck E.

Cancer Res. 2019 Mar 15;79(6):1226-1238. doi: 10.1158/0008-5472.CAN-18-2076. Epub 2019 Jan 23.

PMID:
30674534
15.

The effects of trehalose glycolipid presentation on cytokine production by GM-CSF macrophages.

Stocker BL, Kodar K, Wahi K, Foster AJ, Harper JL, Mori D, Yamasaki S, Timmer MSM.

Glycoconj J. 2019 Feb;36(1):69-78. doi: 10.1007/s10719-018-09857-9. Epub 2019 Jan 8.

PMID:
30617946
16.

Survival effects of a strategy favoring second-line multimodal treatment compared to supportive care in glioblastoma patients at first progression.

Stavrinou P, Kalyvas A, Grau S, Hamisch C, Galldiks N, Katsigiannis S, Kabbasch C, Timmer M, Goldbrunner R, Stranjalis G.

J Neurosurg. 2018 Nov 1:1-6. doi: 10.3171/2018.7.JNS18228. [Epub ahead of print]

PMID:
30544353
17.

Measurement of joint health in persons with haemophilia: A systematic review of the measurement properties of haemophilia-specific instruments.

Gouw SC, Timmer MA, Srivastava A, de Kleijn P, Hilliard P, Peters M, Blanchette V, Fischer K.

Haemophilia. 2019 Jan;25(1):e1-e10. doi: 10.1111/hae.13631. Epub 2018 Nov 14.

PMID:
30427100
18.

Long-Term Outcome after Joint Bleeds in Von Willebrand Disease Compared to Haemophilia A: A Post Hoc Analysis.

van Galen KPM, Timmer M, de Kleijn P, Leebeek FWG, Foppen W, Schutgens REG, Eikenboom J, Meijer K, Fijnvandraat K, Laros-van Gorkom BAP, Twisk JW, Mauser-Bunschoten EP, Fischer K; WiN Studygroup.

Thromb Haemost. 2018 Oct;118(10):1690-1700. doi: 10.1055/s-0038-1670704. Epub 2018 Oct 1.

PMID:
30273954
19.

ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR.

Röhn G, Koch A, Krischek B, Stavrinou P, Goldbrunner R, Timmer M.

Technol Cancer Res Treat. 2018 Jan 1;17:1533033818802318. doi: 10.1177/1533033818802318.

20.

Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells.

Haas B, Schütte L, Wos-Maganga M, Weickhardt S, Timmer M, Eckstein N.

Int J Mol Sci. 2018 Sep 21;19(10). pii: E2874. doi: 10.3390/ijms19102874.

21.

Impact of aneurysm shape on morbidity after clipping of unruptured intracranial aneurysms.

Goertz L, Kasuya H, Hamisch C, Kabbasch C, von Spreckelsen N, Ludyga D, Timmer M, Stavrinou P, Goldbrunner R, Brinker G, Krischek B.

Acta Neurochir (Wien). 2018 Nov;160(11):2169-2176. doi: 10.1007/s00701-018-3675-9. Epub 2018 Sep 17.

PMID:
30225810
22.

Preoperative Three-Dimensional Angiography May Reduce Ischemic Complications During Clipping of Ruptured Intracranial Aneurysms.

Goertz L, Kabbasch C, Borggrefe J, Hamisch C, Telentschak S, von Spreckelsen N, Stavrinou P, Timmer M, Brinker G, Goldbrunner R, Krischek B.

World Neurosurg. 2018 Dec;120:e1163-e1170. doi: 10.1016/j.wneu.2018.09.026. Epub 2018 Sep 12.

PMID:
30218797
23.

Epineurial Nerve Coaptation: A Biological Nonliving Training Model Using Gradually Thawed Cryopreserved Sciatic Nerves.

Safi AF, Safi S, Timmer M, Goldbrunner R, Kauke M.

J Craniofac Surg. 2018 Oct;29(7):e708-e712. doi: 10.1097/SCS.0000000000004998.

PMID:
30192297
24.

Enhanced motivation of cognitive control in Parkinson's disease.

Timmer MHM, Aarts E, Esselink RAJ, Cools R.

Eur J Neurosci. 2018 Sep;48(6):2374-2384. doi: 10.1111/ejn.14137. Epub 2018 Sep 16.

25.

Mechanisms Underlying Dopamine-Induced Risky Choice in Parkinson's Disease With and Without Depression (History).

Timmer MHM, Sescousse G, Esselink RAJ, Piray P, Cools R.

Comput Psychiatr. 2018 Feb 1;2:11-27. doi: 10.1162/CPSY_a_00011. eCollection 2018 Feb.

26.

Impact of Aneurysm Shape on Intraoperative Rupture During Clipping of Ruptured Intracranial Aneurysms.

Goertz L, Hamisch C, Telentschak S, Kabbasch C, von Spreckelsen N, Stavrinou P, Timmer M, Goldbrunner R, Brinker G, Krischek B.

World Neurosurg. 2018 Oct;118:e806-e812. doi: 10.1016/j.wneu.2018.07.058. Epub 2018 Jul 18.

PMID:
30031199
27.

Fully automated detection and segmentation of meningiomas using deep learning on routine multiparametric MRI.

Laukamp KR, Thiele F, Shakirin G, Zopfs D, Faymonville A, Timmer M, Maintz D, Perkuhn M, Borggrefe J.

Eur Radiol. 2019 Jan;29(1):124-132. doi: 10.1007/s00330-018-5595-8. Epub 2018 Jun 25.

28.

Methyl group reorientation under ligand binding probed by pseudocontact shifts.

Lescanne M, Ahuja P, Blok A, Timmer M, Akerud T, Ubbink M.

J Biomol NMR. 2018 Aug;71(4):275-285. doi: 10.1007/s10858-018-0190-5. Epub 2018 Jun 2.

29.

A novel microsurgical anastomosis training model using gradually thawed cryopreserved microvessels of rat cadavers.

Safi AF, Safi S, Tayeh M, Timmer M, Goldbrunner R, Kauke M.

J Craniomaxillofac Surg. 2018 Jul;46(7):1126-1131. doi: 10.1016/j.jcms.2018.05.018. Epub 2018 May 22.

PMID:
29802058
30.

Synthesis of Branched Trehalose Glycolipids and Their Mincle Agonist Activity.

Bird JH, Khan AA, Nishimura N, Yamasaki S, Timmer MSM, Stocker BL.

J Org Chem. 2018 Aug 3;83(15):7593-7605. doi: 10.1021/acs.joc.7b03269. Epub 2018 Jun 12.

PMID:
29781274
31.

Early or late cranioplasty following decompressive craniotomy for traumatic brain injury: A systematic review and meta-analysis.

Zheng F, Xu H, von Spreckelsen N, Stavrinou P, Timmer M, Goldbrunner R, Cao F, Ran Q, Li G, Fan R, Zhang Q, Chen W, Yao S, Krischek B.

J Int Med Res. 2018 Jul;46(7):2503-2512. doi: 10.1177/0300060518755148. Epub 2018 May 21.

32.

Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs.

Haas B, Klinger V, Keksel C, Bonigut V, Kiefer D, Caspers J, Walther J, Wos-Maganga M, Weickhardt S, Röhn G, Timmer M, Frötschl R, Eckstein N.

Cancer Cell Int. 2018 May 4;18:69. doi: 10.1186/s12935-018-0565-4. eCollection 2018.

33.

Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma?

Safi AF, Kauke M, Jung H, Timmer M, Borggrefe J, Persigehl T, Nickenig HJ, Zinser M, Maintz D, Kreppel M, Zöller J.

J Craniomaxillofac Surg. 2018 Jun;46(6):1013-1018. doi: 10.1016/j.jcms.2018.04.001. Epub 2018 Apr 10.

PMID:
29709330
34.

Integrated genomic analyses of de novo pathways underlying atypical meningiomas.

Harmancı AS, Youngblood MW, Clark VE, Coşkun S, Henegariu O, Duran D, Erson-Omay EZ, Kaulen LD, Lee TI, Abraham BJ, Simon M, Krischek B, Timmer M, Goldbrunner R, Omay SB, Baranoski J, Baran B, Carrión-Grant G, Bai H, Mishra-Gorur K, Schramm J, Moliterno J, Vortmeyer AO, Bilgüvar K, Yasuno K, Young RA, Günel M.

Nat Commun. 2018 Apr 20;9:16215. doi: 10.1038/ncomms16215.

35.

Dopaminergic Drug Effects on Probability Weighting during Risky Decision Making.

Ojala KE, Janssen LK, Hashemi MM, Timmer MHM, Geurts DEM, Ter Huurne NP, Cools R, Sescousse G.

eNeuro. 2018 Apr 6;5(2). pii: ENEURO.0330-18.2018. doi: 10.1523/ENEURO.0330-18.2018. eCollection 2018 Mar-Apr.

36.

Quality of Care for PTSD and Depression in the Military Health System: Final Report.

Hepner KA, Roth CP, Sloss EM, Paddock SM, Iyiewuare PO, Timmer MJ, Pincus HA.

Rand Health Q. 2018 Apr 1;7(3):4. eCollection 2018 Apr.

37.

Does volumetric measurement serve as an imaging biomarker for tumor aggressiveness of ameloblastomas?

Safi AF, Kauke M, Timmer M, Grandoch A, Nickenig HJ, Gültekin E, Büttner R, Kreppel M, Zöller J.

Oral Oncol. 2018 Mar;78:16-24. doi: 10.1016/j.oraloncology.2018.01.002. Epub 2018 Jan 10. No abstract available.

PMID:
29496045
38.

Review on the conversion of thermoacoustic power into electricity.

Timmer MAG, de Blok K, van der Meer TH.

J Acoust Soc Am. 2018 Feb;143(2):841. doi: 10.1121/1.5023395.

PMID:
29495704
39.

Movement behaviour in adults with haemophilia compared to healthy adults.

Timmer MA, Pisters MF, de Kleijn P, de Bie RA, Schutgens REG, Veenhof C.

Haemophilia. 2018 May;24(3):445-451. doi: 10.1111/hae.13441. Epub 2018 Mar 1.

PMID:
29493876
40.

FAMI Screws for Mandibulo-Maxillary fixation in mandibular fracture treatment - Clinico-radiological evaluation.

Kauke M, Safi AF, Timmer M, Nickenig HJ, Zöller J, Kreppel M.

J Craniomaxillofac Surg. 2018 Apr;46(4):566-572. doi: 10.1016/j.jcms.2018.01.003. Epub 2018 Feb 2.

PMID:
29459185
41.

Identification and Biological Activity of Synthetic Macrophage Inducible C-Type Lectin Ligands.

Braganza CD, Teunissen T, Timmer MSM, Stocker BL.

Front Immunol. 2018 Jan 17;8:1940. doi: 10.3389/fimmu.2017.01940. eCollection 2017. Review.

42.

Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants.

Foster AJ, Nagata M, Lu X, Lynch AT, Omahdi Z, Ishikawa E, Yamasaki S, Timmer MSM, Stocker BL.

J Med Chem. 2018 Feb 8;61(3):1045-1060. doi: 10.1021/acs.jmedchem.7b01468. Epub 2018 Jan 18.

PMID:
29290115
43.

Expression of FAS-L Differs from Primary to Relapsed Low-grade Gliomas and Predicts Progression-free Survival.

Werner JM, Kuhl S, Stavrinou P, Röhn G, Krischek B, Blau T, Goldbrunner R, Timmer M.

Anticancer Res. 2017 Dec;37(12):6639-6648.

PMID:
29187439
44.

Methyl group assignment using pseudocontact shifts with PARAssign.

Lescanne M, Skinner SP, Blok A, Timmer M, Cerofolini L, Fragai M, Luchinat C, Ubbink M.

J Biomol NMR. 2017 Dec;69(4):183-195. doi: 10.1007/s10858-017-0136-3. Epub 2017 Nov 27.

45.

Measuring activities and participation in persons with haemophilia: A systematic review of commonly used instruments.

Timmer MA, Gouw SC, Feldman BM, Zwagemaker A, de Kleijn P, Pisters MF, Schutgens REG, Blanchette V, Srivastava A, David JA, Fischer K, van der Net J.

Haemophilia. 2018 Mar;24(2):e33-e49. doi: 10.1111/hae.13367. Epub 2017 Nov 27. Review.

PMID:
29178149
46.

Phosphate Promotes the Recovery of Mycobacterium tuberculosis β-Lactamase from Clavulanic Acid Inhibition.

Elings W, Tassoni R, van der Schoot SA, Luu W, Kynast JP, Dai L, Blok AJ, Timmer M, Florea BI, Pannu NS, Ubbink M.

Biochemistry. 2017 Nov 28;56(47):6257-6267. doi: 10.1021/acs.biochem.7b00556. Epub 2017 Nov 14.

47.

Should preventive antibiotics be used in patients with acute stroke? A systematic review and meta-analysis of randomized controlled trials.

Zheng F, Spreckelsen NV, Zhang X, Stavrinou P, Timmer M, Dohmen C, Goldbrunner R, Cao F, Zhang Q, Ran Q, Li G, Fan R, Yao S, Krischek B.

PLoS One. 2017 Oct 19;12(10):e0186607. doi: 10.1371/journal.pone.0186607. eCollection 2017. Review.

48.

Monitoring joint health in haemophilia: Factors associated with deterioration.

Kuijlaars IAR, Timmer MA, de Kleijn P, Pisters MF, Fischer K.

Haemophilia. 2017 Nov;23(6):934-940. doi: 10.1111/hae.13327. Epub 2017 Sep 5.

PMID:
28873289
49.

Discordance and Conversion Rates of Progesterone-, Estrogen-, and HER2/neu-Receptor Status in Primary Breast Cancer and Brain Metastasis Mainly Triggered by Hormone Therapy.

Timmer M, Werner JM, Röhn G, Ortmann M, Blau T, Cramer C, Stavrinou P, Krischek B, Mallman P, Goldbrunner R.

Anticancer Res. 2017 Sep;37(9):4859-4865.

PMID:
28870906
50.

What a neurologist should know about depression in Parkinson's disease.

Timmer MHM, van Beek MHCT, Bloem BR, Esselink RAJ.

Pract Neurol. 2017 Oct;17(5):359-368. doi: 10.1136/practneurol-2017-001650. Epub 2017 Jul 24. Review.

PMID:
28739866

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