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Items: 1 to 50 of 108

1.

Sulfur amino acid deprivation in cadmium chloride toxicity in hepatoma cells.

Fotakis G, Timbrell JA.

Environ Toxicol Pharmacol. 2006 Nov;22(3):334-7. doi: 10.1016/j.etap.2006.04.006. Epub 2006 May 7.

PMID:
21783728
2.

Modulation of cadmium chloride toxicity by sulphur amino acids in hepatoma cells.

Fotakis G, Timbrell JA.

Toxicol In Vitro. 2006 Aug;20(5):641-8. Epub 2006 Jan 26.

PMID:
16442773
3.

Role of trace elements in cadmium chloride uptake in hepatoma cell lines.

Fotakis G, Timbrell JA.

Toxicol Lett. 2006 Jul 1;164(2):97-103. Epub 2006 Jan 6.

PMID:
16406389
4.
5.

Cadmium chloride-induced DNA and lysosomal damage in a hepatoma cell line.

Fotakis G, Cemeli E, Anderson D, Timbrell JA.

Toxicol In Vitro. 2005 Jun;19(4):481-9.

PMID:
15826806
6.

Methionine synthase activity and sulphur amino acid levels in the rat liver tumour cells HTC and Phi-1.

Kenyon SH, Waterfield CJ, Timbrell JA, Nicolaou A.

Biochem Pharmacol. 2002 Feb 1;63(3):381-91.

PMID:
11853689
7.

Urinary creatine as a biochemical marker of chemical induced testicular damage.

Timbrell JA.

Arh Hig Rada Toksikol. 2000 Sep;51(3):295-303.

PMID:
11148934
8.

The effect of taurine depletion by beta-alanine treatment on the susceptibility to ethanol-induced hepatic dysfunction in rats.

Kerai MD, Waterfield CJ, Kenyon SH, Asker DS, Timbrell JA.

Alcohol Alcohol. 2001 Jan-Feb;36(1):29-38.

PMID:
11139413
9.

The use of liver spheroids as an in vitro model for studying induction of the stress response as a marker of chemical toxicity.

Dilworth C, Hamilton GA, George E, Timbrell JA.

Toxicol In Vitro. 2000 Apr;14(2):169-76.

PMID:
10793295
10.

Reversal of ethanol-induced hepatic steatosis and lipid peroxidation by taurine: a study in rats.

Kerai MD, Waterfield CJ, Kenyon SH, Asker DS, Timbrell JA.

Alcohol Alcohol. 1999 Jul-Aug;34(4):529-41.

PMID:
10456581
11.

Effect of hydrazine upon vitamin B12-dependent methionine synthase activity and the sulphur amino acid pathway in isolated rat hepatocytes.

Kenyon SH, Waterfield CJ, Asker DS, Kudo M, Moss DW, Bates TE, Nicolaou A, Gibbons WA, Timbrell JA.

Biochem Pharmacol. 1999 Jun 1;57(11):1311-9.

PMID:
10230775
12.

Editorial.

Timbrell JA.

Biomarkers. 1999;4(1):1. doi: 10.1080/135475099230958. No abstract available.

PMID:
23898790
13.
14.

Taurine: protective properties against ethanol-induced hepatic steatosis and lipid peroxidation during chronic ethanol consumption in rats.

Kerai MD, Waterfield CJ, Kenyon SH, Asker DS, Timbrell JA.

Amino Acids. 1998;15(1-2):53-76.

PMID:
9871487
15.

The effects of the beta 2-agonist drug clenbuterol on taurine levels in heart and other tissues in the rat.

Doheny MH, Waterfield CJ, Timbrell JA.

Amino Acids. 1998;15(1-2):13-25.

PMID:
9871484
16.

Ethionine toxicity in vitro: the correlation of data from rat hepatocyte suspensions and monolayers with in vivo observations.

Waterfield CJ, Westmoreland C, Asker DS, Murdock JC, George E, Timbrell JA.

Arch Toxicol. 1998 Sep;72(9):588-96.

PMID:
9806431
17.

Biomarkers in toxicology.

Timbrell JA.

Toxicology. 1998 Aug 7;129(1):1-12. Review.

PMID:
9769106
19.

Creatine metabolism in the seminiferous epithelium of rats. I. Creatine synthesis by isolated and cultured cells.

Moore NP, Gray TJ, Timbrell JA.

J Reprod Fertil. 1998 Mar;112(2):325-30.

PMID:
9640271
20.

Triglyceride disposition in isolated hepatocytes after treatment with hydrazine.

Waterfield CJ, Asker DS, Timbrell JA.

Chem Biol Interact. 1997 Nov 28;107(3):157-72.

PMID:
9448750
21.

Modulation of taurine levels in the rat liver alters methylene dianiline hepatotoxicity.

Seabra V, Timbrell JA.

Toxicology. 1997 Oct 19;122(3):193-204.

PMID:
9328219
22.

Effect of fructose on the biochemical toxicity of hydrazine in isolated rat hepatocytes.

Kerai MD, Timbrell JA.

Toxicology. 1997 Jul 11;120(3):221-30.

PMID:
9217309
23.

Correlations between in vivo and in vitro effects of toxic compounds: Studies with hydrazine.

Waterfield CJ, Delaney J, Kerai MD, Timbrell JA.

Toxicol In Vitro. 1997 Jun;11(3):217-27.

PMID:
20654308
24.

Changes in taurine levels in response to repeated administration of the beta 2-agonist salbutamol in lambs.

Bastos ML, Carvalho F, Remião F, Mendes ME, Ferreira MA, Soares ME, Timbrell JA.

J Vet Pharmacol Ther. 1997 Feb;20(1):33-7.

PMID:
9049947
25.

The biosynthesis of taurine fromN-acetyl-L-cysteine and other precursorsin vivo and in rat hepatocytes.

Waterfield CJ, Timbrell JA.

Amino Acids. 1996 Jun;10(2):173-85. doi: 10.1007/BF00806590.

PMID:
24178479
26.

Comparison of urinary creatine with other biomarkers for the detection of 2-methoxyethanol-induced testicular damage.

Draper RP, Creasy DM, Timbrell JA.

Biomarkers. 1996;1(3):190-5. doi: 10.3109/13547509609079356.

PMID:
23902324
27.

Does urinary taurine reflect changes in protein metabolism? A study with cycloheximide in rats.

Waterfield CJ, Asker DS, Timbrell JA.

Biomarkers. 1996;1(2):107-14. doi: 10.3109/13547509609088678.

PMID:
23888921
28.

Urinary creatine as a potential marker of testicular damage: effect of vasectomy.

Draper RP, Timbrell JA.

Reprod Toxicol. 1996 Jan-Feb;10(1):79-85.

PMID:
8998389
29.
30.
31.

Role of cytochrome P450 in hydrazine toxicity in isolated hepatocytes in vitro.

Delaney J, Timbrell JA.

Xenobiotica. 1995 Dec;25(12):1399-410.

PMID:
8719914
32.

The biochemical effects of clenbuterol: with particular reference to taurine and muscle damage.

Waterfield CJ, Jairath M, Asker DS, Timbrell JA.

Eur J Pharmacol. 1995 Jul 1;293(2):141-9.

PMID:
7589228
33.

In vitro microsomal metabolism of hydrazine.

Jenner AM, Timbrell JA.

Xenobiotica. 1995 Jun;25(6):599-609.

PMID:
7483660
34.

The in vivo and in vitro protective properties of taurine.

Timbrell JA, Seabra V, Waterfield CJ.

Gen Pharmacol. 1995 May;26(3):453-62. Review.

PMID:
7789717
35.

The detection of subchronic testicular damage using urinary creatine: studies with 2-methoxyethanol.

Butterworth M, Creasy D, Timbrell JA.

Arch Toxicol. 1995;69(3):209-11.

PMID:
7717879
36.

Cytoprotective effects of taurine in isolated rat hepatocytes.

Waterfield CJ, Mesquita M, Parnham P, Timbrell JA.

Toxicol In Vitro. 1994 Aug;8(4):573-5.

PMID:
20692963
37.

Toxicity of alpha-naphthylisothiocyanate in isolated hepatocytes: Possible role of taurine.

Seabra V, Timbrell JA.

Toxicol In Vitro. 1994 Aug;8(4):569-72.

PMID:
20692962
38.

The biochemical effects and toxicity of hydrazine in cultured rat hepatocytes.

Ghatineh S, Timbrell JA.

Toxicol In Vitro. 1994 Jun;8(3):393-9.

PMID:
20692930
39.

Glutathione and cysteine measurement in biological samples by HPLC with a glassy carbon working detector.

Carvalho FD, Remião F, Vale P, Timbrell JA, Bastos ML, Ferreira MA.

Biomed Chromatogr. 1994 May-Jun;8(3):134-6. Erratum in: Biomed Chromatogr 1994 Nov-Dec;8(6):followi.

PMID:
8075522
40.
42.
43.

Depletion of total non-protein sulphydryl groups in mouse tissues after administration of d-amphetamine.

Carvalho FD, Bastos Mde L, Timbrell JA.

Toxicology. 1993 Oct 25;83(1-3):31-40.

PMID:
8248948
44.

Taurine protects against the cytotoxicity of hydrazine, 1,4-naphthoquinone and carbon tetrachloride in isolated rat hepatocytes.

Waterfield CJ, Mesquita M, Parnham P, Timbrell JA.

Biochem Pharmacol. 1993 Aug 17;46(4):589-95.

PMID:
8363631
45.

Reduction of liver taurine in rats by beta-alanine treatment increases carbon tetrachloride toxicity.

Waterfield CJ, Turton JA, Scales MD, Timbrell JA.

Toxicology. 1993 Jan 29;77(1-2):7-20.

PMID:
8442020
46.

The correlation between urinary and liver taurine levels and between pre-dose urinary taurine and liver damage.

Waterfield CJ, Turton JA, Scales MD, Timbrell JA.

Toxicology. 1993 Jan 29;77(1-2):1-5.

PMID:
8442006
47.

Investigations into the effects of various hepatotoxic compounds on urinary and liver taurine levels in rats.

Waterfield CJ, Turton JA, Scales MD, Timbrell JA.

Arch Toxicol. 1993;67(4):244-54.

PMID:
8517780
48.

Effect of various non-hepatotoxic compounds on urinary and liver taurine levels in rats.

Waterfield CJ, Turton JA, Scales MD, Timbrell JA.

Arch Toxicol. 1993;67(8):538-46.

PMID:
8285852
49.

Studies on the disposition and metabolism of hydrazine in rats in vivo.

Preece NE, Ghatineh S, Timbrell JA.

Hum Exp Toxicol. 1992 Mar;11(2):121-7.

PMID:
1349218
50.

Determination of hydrazine in biofluids by capillary gas chromatography with nitrogen-sensitive or mass spectrometric detection.

Preece NE, Forrow S, Ghatineh S, Langley GJ, Timbrell JA.

J Chromatogr. 1992 Jan 17;573(2):227-34.

PMID:
1601955

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