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Association Between Age at Puberty and Bone Accrual From 10 to 25 Years of Age.

Elhakeem A, Frysz M, Tilling K, Tobias JH, Lawlor DA.

JAMA Netw Open. 2019 Aug 2;2(8):e198918. doi: 10.1001/jamanetworkopen.2019.8918.


Identifying Novel Types of Irritability Using a Developmental Genetic Approach.

Riglin L, Eyre O, Thapar AK, Stringaris A, Leibenluft E, Pine DS, Tilling K, Davey Smith G, O'Donovan MC, Thapar A.

Am J Psychiatry. 2019 Aug 1;176(8):635-642. doi: 10.1176/appi.ajp.2019.18101134. Epub 2019 Jul 1.


Association of Maternal Neurodevelopmental Risk Alleles With Early-Life Exposures.

Leppert B, Havdahl A, Riglin L, Jones HJ, Zheng J, Davey Smith G, Tilling K, Thapar A, Reichborn-Kjennerud T, Stergiakouli E.

JAMA Psychiatry. 2019 May 1. doi: 10.1001/jamapsychiatry.2019.0774. [Epub ahead of print]


Residential exposure to radon and DNA methylation across the lifecourse: an exploratory study in the ALSPAC birth cohort.

de Vocht F, Suderman M, Ruano-Ravina A, Thomas R, Wakeford R, Relton C, Tilling K, Boyd A.

Version 2. Wellcome Open Res. 2019 Apr 15 [revised 2019 Jan 1];4:3. doi: 10.12688/wellcomeopenres.14991.2. eCollection 2019.


Genetic and observational evidence supports a causal role of sex hormones on the development of asthma.

Arathimos R, Granell R, Haycock P, Richmond RC, Yarmolinsky J, Relton CL, Tilling K.

Thorax. 2019 Jul;74(7):633-642. doi: 10.1136/thoraxjnl-2018-212207. Epub 2019 Apr 1.


Selection Bias When Estimating Average Treatment Effects Using One-sample Instrumental Variable Analysis.

Hughes RA, Davies NM, Davey Smith G, Tilling K.

Epidemiology. 2019 May;30(3):350-357. doi: 10.1097/EDE.0000000000000972.


Predictors of future suicide attempt among adolescents with suicidal thoughts or non-suicidal self-harm: a population-based birth cohort study.

Mars B, Heron J, Klonsky ED, Moran P, O'Connor RC, Tilling K, Wilkinson P, Gunnell D.

Lancet Psychiatry. 2019 Apr;6(4):327-337. doi: 10.1016/S2215-0366(19)30030-6. Epub 2019 Mar 14.


Accounting for missing data in statistical analyses: multiple imputation is not always the answer.

Hughes RA, Heron J, Sterne JAC, Tilling K.

Int J Epidemiol. 2019 Mar 16. pii: dyz032. doi: 10.1093/ije/dyz032. [Epub ahead of print]


The proportion of missing data should not be used to guide decisions on multiple imputation.

Madley-Dowd P, Hughes R, Tilling K, Heron J.

J Clin Epidemiol. 2019 Jun;110:63-73. doi: 10.1016/j.jclinepi.2019.02.016. Epub 2019 Mar 13.


Data on trajectories of measures of cardiovascular health in the Avon Longitudinal Study of Parents and Children (ALSPAC).

O'Keeffe LM, Simpkin AJ, Tilling K, Anderson EL, Hughes AD, Lawlor DA, Fraser A, Howe LD.

Data Brief. 2019 Jan 19;23:103687. doi: 10.1016/j.dib.2019.01.035. eCollection 2019 Apr.


A discussion of statistical methods to characterise early growth and its impact on bone mineral content later in childhood.

Crozier SR, Johnson W, Cole TJ, Macdonald-Wallis C, Muniz-Terrera G, Inskip HM, Tilling K.

Ann Hum Biol. 2019 Feb;46(1):17-26. doi: 10.1080/03014460.2019.1574896. Epub 2019 Apr 15.


Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization.

Millard LAC, Davies NM, Tilling K, Gaunt TR, Davey Smith G.

PLoS Genet. 2019 Feb 1;15(2):e1007951. doi: 10.1371/journal.pgen.1007951. eCollection 2019 Feb.


The impact of opiate substitution treatment on mortality risk in drug addicts: a natural experiment study.

Steer CD, Macleod J, Tilling K, Lim AG, Marsden J, Millar T, Strang J, Telfer M, Whitaker H, Vickerman P, Hickman M.

Southampton (UK): NIHR Journals Library; 2019 Jan.


Forecasting the 2021 local burden of population alcohol-related harms using Bayesian structural time-series.

McQuire C, Tilling K, Hickman M, de Vocht F.

Addiction. 2019 Jun;114(6):994-1003. doi: 10.1111/add.14568. Epub 2019 Mar 6.


The effect of a lifestyle intervention in obese pregnant women on gestational metabolic profiles: findings from the UK Pregnancies Better Eating and Activity Trial (UPBEAT) randomised controlled trial.

Mills HL, Patel N, White SL, Pasupathy D, Briley AL, Santos Ferreira DL, Seed PT, Nelson SM, Sattar N, Tilling K, Poston L, Lawlor DA; UPBEAT Consortium.

BMC Med. 2019 Jan 21;17(1):15. doi: 10.1186/s12916-018-1248-7.


Is screen time associated with anxiety or depression in young people? Results from a UK birth cohort.

Khouja JN, Munafò MR, Tilling K, Wiles NJ, Joinson C, Etchells PJ, John A, Hayes FM, Gage SH, Cornish RP.

BMC Public Health. 2019 Jan 17;19(1):82. doi: 10.1186/s12889-018-6321-9.


Association of Primary Care Consultation Patterns With Early Signs and Symptoms of Psychosis.

Sullivan SA, Hamilton W, Tilling K, Redaniel T, Moran P, Lewis G.

JAMA Netw Open. 2018 Nov 2;1(7):e185174. doi: 10.1001/jamanetworkopen.2018.5174.


Prevalence of Prenatal Depression Symptoms Among 2 Generations of Pregnant Mothers: The Avon Longitudinal Study of Parents and Children.

Pearson RM, Carnegie RE, Cree C, Rollings C, Rena-Jones L, Evans J, Stein A, Tilling K, Lewcock M, Lawlor DA.

JAMA Netw Open. 2018 Jul 6;1(3):e180725. doi: 10.1001/jamanetworkopen.2018.0725.


Adverse childhood experiences in the children of the Avon Longitudinal Study of Parents and Children (ALSPAC).

Houtepen LC, Heron J, Suderman MJ, Tilling K, Howe LD.

Wellcome Open Res. 2018 Aug 30;3:106. doi: 10.12688/wellcomeopenres.14716.1. eCollection 2018.


Associations of sex hormone-binding globulin and testosterone with genome-wide DNA methylation.

Arathimos R, Sharp GC, Granell R, Tilling K, Relton CL.

BMC Genet. 2018 Dec 14;19(1):113. doi: 10.1186/s12863-018-0703-y.


Transition to parenthood and mental health at 30 years: a prospective comparison of mothers and fathers in a large Brazilian birth cohort.

Pearson RM, Culpin I, Loret de Mola C, Quevedo L, Murray J, Matijasevich A, Tilling K, Barros FC, Stein A, Horta BL.

Arch Womens Ment Health. 2018 Dec 6. doi: 10.1007/s00737-018-0935-x. [Epub ahead of print]


High-risk environments for eating foods surplus to requirements: a multilevel analysis of adolescents' non-core food intake in the National Diet and Nutrition Survey (NDNS).

Toumpakari Z, Tilling K, Haase AM, Johnson L.

Public Health Nutr. 2019 Jan;22(1):74-84. doi: 10.1017/S1368980018002860. Epub 2018 Nov 8.


Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort.

Brand JS, West J, Tuffnell D, Bird PK, Wright J, Tilling K, Lawlor DA.

BMC Med. 2018 Nov 6;16(1):203. doi: 10.1186/s12916-018-1191-7.


Life Course Trajectories of Cardiovascular Risk Factors in Women With and Without Hypertensive Disorders in First Pregnancy: The HUNT Study in Norway.

Haug EB, Horn J, Markovitz AR, Fraser A, Vatten LJ, Macdonald-Wallis C, Tilling K, Romundstad PR, Rich-Edwards JW, Åsvold BO.

J Am Heart Assoc. 2018 Aug 7;7(15):e009250. doi: 10.1161/JAHA.118.009250.


The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation.

Rooshenas L, Scott LJ, Blazeby JM, Rogers CA, Tilling KM, Husbands S, Conefrey C, Mills N, Stein RC, Metcalfe C, Carr AJ, Beard DJ, Davis T, Paramasivan S, Jepson M, Avery K, Elliott D, Wilson C, Donovan JL; By-Band-Sleeve study group; CSAW study group; HAND-1 study group; Optima prelim study group; Romio feasibility study group.

J Clin Epidemiol. 2019 Feb;106:108-120. doi: 10.1016/j.jclinepi.2018.10.004. Epub 2018 Oct 16.


Independent and combined associations of maternal and own smoking with adult lung function and COPD.

Magnus MC, Henderson J, Tilling K, Howe LD, Fraser A.

Int J Epidemiol. 2018 Dec 1;47(6):1855-1864. doi: 10.1093/ije/dyy221.


Does pregnancy alter life-course lipid trajectories? Evidence from the HUNT Study in Norway.

Markovitz AR, Haug EB, Horn J, Fraser A, Macdonald-Wallis C, Tilling K, Rimm EB, Missmer SA, Williams PL, Romundstad PR, Åsvold BO, Rich-Edwards JW.

J Lipid Res. 2018 Dec;59(12):2403-2412. doi: 10.1194/jlr.P085720. Epub 2018 Oct 12.


Sex-specific trajectories of measures of cardiovascular health during childhood and adolescence: A prospective cohort study.

O'Keeffe LM, Simpkin AJ, Tilling K, Anderson EL, Hughes AD, Lawlor DA, Fraser A, Howe LD.

Atherosclerosis. 2018 Nov;278:190-196. doi: 10.1016/j.atherosclerosis.2018.09.030. Epub 2018 Sep 27.


Assessing the long-term effectiveness of interferon-beta and glatiramer acetate in multiple sclerosis: final 10-year results from the UK multiple sclerosis risk-sharing scheme.

Palace J, Duddy M, Lawton M, Bregenzer T, Zhu F, Boggild M, Piske B, Robertson NP, Oger J, Tremlett H, Tilling K, Ben-Shlomo Y, Lilford R, Dobson C.

J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):251-260. doi: 10.1136/jnnp-2018-318360. Epub 2018 Sep 21.


Is teachers' mental health and wellbeing associated with students' mental health and wellbeing?

Harding S, Morris R, Gunnell D, Ford T, Hollingworth W, Tilling K, Evans R, Bell S, Grey J, Brockman R, Campbell R, Araya R, Murphy S, Kidger J.

J Affect Disord. 2019 Jan 1;242:180-187. doi: 10.1016/j.jad.2018.08.080. Epub 2018 Aug 17.


Frailty in older-age European migrants: Cross-sectional and longitudinal analyses of the Survey of Health, Aging and Retirement in Europe (SHARE).

Walkden GJ, Anderson EL, Vink MP, Tilling K, Howe LD, Ben-Shlomo Y.

Soc Sci Med. 2018 Sep;213:1-11. doi: 10.1016/j.socscimed.2018.07.033. Epub 2018 Jul 21.


Association of Height Growth in Puberty with Lung Function: A Longitudinal Study.

Mahmoud O, Granell R, Tilling K, Minelli C, Garcia-Aymerich J, Holloway JW, Custovic A, Jarvis D, Sterne J, Henderson J.

Am J Respir Crit Care Med. 2018 Jul 11. doi: 10.1164/rccm.201802-0274OC. [Epub ahead of print]


Correction to: The impact of parity on life course blood pressure trajectories: the HUNT study in Norway.

Haug EB, Horn J, Markovitz AR, Fraser A, Macdonald-Wallis C, Tilling K, Romundstad PR, Rich-Edwards JW, Åsvold BO.

Eur J Epidemiol. 2018 Sep;33(9):895. doi: 10.1007/s10654-018-0412-x.


Causal Inference in Cancer Epidemiology: What Is the Role of Mendelian Randomization?

Yarmolinsky J, Wade KH, Richmond RC, Langdon RJ, Bull CJ, Tilling KM, Relton CL, Lewis SJ, Davey Smith G, Martin RM.

Cancer Epidemiol Biomarkers Prev. 2018 Sep;27(9):995-1010. doi: 10.1158/1055-9965.EPI-17-1177. Epub 2018 Jun 25. Review.


Response to: 'Synthetic control methodology as a tool for evaluating population-level health interventions' by Bouttell et al.

de Vocht F, Angus C, Tilling K, Brennan A, Hickman M.

J Epidemiol Community Health. 2018 Sep;72(9):864. doi: 10.1136/jech-2018-211037. Epub 2018 Jun 11. No abstract available.


Long terms trends in CD4+ cell counts, CD8+ cell counts, and the CD4+ :  CD8+ ratio.

Hughes RA, May MT, Tilling K, Taylor N, Wittkop L, Reiss P, Gill J, Schommers P, Costagliola D, Guest JL, Lima VD, d'Arminio Monforte A, Smith C, Cavassini M, Saag M, Castilho JL, Sterne JAC.

AIDS. 2018 Jun 19;32(10):1361-1367. doi: 10.1097/QAD.0000000000001848.


Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children.

Taylor AE, Jones HJ, Sallis H, Euesden J, Stergiakouli E, Davies NM, Zammit S, Lawlor DA, Munafò MR, Davey Smith G, Tilling K.

Int J Epidemiol. 2018 Aug 1;47(4):1207-1216. doi: 10.1093/ije/dyy060.


Derivative estimation for longitudinal data analysis: Examining features of blood pressure measured repeatedly during pregnancy.

Simpkin AJ, Durban M, Lawlor DA, MacDonald-Wallis C, May MT, Metcalfe C, Tilling K.

Stat Med. 2018 May 20. doi: 10.1002/sim.7694. [Epub ahead of print]


Childhood sleep and adolescent chronic fatigue syndrome (CFS/ME): evidence of associations in a UK birth cohort.

Collin SM, Norris T, Gringras P, Blair PS, Tilling K, Crawley E.

Sleep Med. 2018 Jun;46:26-36. doi: 10.1016/j.sleep.2018.01.005. Epub 2018 Jan 31.


Long-term trends in CD4 cell counts, CD8 cell counts, and the CD4: CD8 ratio: ART Cohort Collaboration (ART-CC) Study.

Hughes RA, May MT, Tilling K, Taylor N, Wittkop L, Reiss P, Gill J, Schommers P, Costagliola D, Guest JL, Lima VD, Monforte AD, Smith C, Cavassini M, Saag M, Sterling TR, Sterne JAC.

AIDS. 2018 May 3. doi: 10.1097/QAD.0000000000001848. [Epub ahead of print]


A cluster randomised controlled trial of the Wellbeing in Secondary Education (WISE) Project - an intervention to improve the mental health support and training available to secondary school teachers: protocol for an integrated process evaluation.

Evans R, Brockman R, Grey J, Bell S, Harding S, Gunnell D, Campbell R, Murphy S, Ford T, Hollingworth W, Tilling K, Morris R, Kadir B, Araya R, Kidger J.

Trials. 2018 May 4;19(1):270. doi: 10.1186/s13063-018-2617-4.


Duration of untreated psychosis and clinical outcomes of first episode psychosis: An observational and an instrumental variables analysis.

Sullivan SA, Carroll R, Peters TJ, Amos T, Jones PB, Marshall M, Birchwood M, Fowler D, Johnson S, Fisher HL, Major B, Rahaman N, Joyce J, Chamberlain-Kent N, Lawrence J, Moran P, Tilling K.

Early Interv Psychiatry. 2019 Aug;13(4):841-847. doi: 10.1111/eip.12676. Epub 2018 Apr 26.


Investigating late-onset ADHD: a population cohort investigation.

Cooper M, Hammerton G, Collishaw S, Langley K, Thapar A, Dalsgaard S, Stergiakouli E, Tilling K, Davey Smith G, Maughan B, O'Donovan M, Thapar A, Riglin L.

J Child Psychol Psychiatry. 2018 Oct;59(10):1105-1113. doi: 10.1111/jcpp.12911. Epub 2018 Apr 23.


The impact of buprenorphine and methadone on mortality: a primary care cohort study in the United Kingdom.

Hickman M, Steer C, Tilling K, Lim AG, Marsden J, Millar T, Strang J, Telfer M, Vickerman P, Macleod J.

Addiction. 2018 Aug;113(8):1461-1476. doi: 10.1111/add.14188. Epub 2018 Apr 19.


Analysis of 'sensitive' periods of fetal and child growth.

Zhang X, Tilling K, Martin RM, Oken E, Naimi AI, Aris IM, Yang S, Kramer MS.

Int J Epidemiol. 2019 Feb 1;48(1):116-123. doi: 10.1093/ije/dyy045.


Socioeconomic differences in childhood BMI trajectories in Belarus.

Patel R, Tilling K, Lawlor DA, Howe LD, Hughes RA, Bogdanovich N, Matush L, Nicoli E, Oken E, Kramer MS, Martin RM.

Int J Obes (Lond). 2018 Sep;42(9):1651-1660. doi: 10.1038/s41366-018-0042-0. Epub 2018 Feb 28.


What distinguishes adolescents with suicidal thoughts from those who have attempted suicide? A population-based birth cohort study.

Mars B, Heron J, Klonsky ED, Moran P, O'Connor RC, Tilling K, Wilkinson P, Gunnell D.

J Child Psychol Psychiatry. 2019 Jan;60(1):91-99. doi: 10.1111/jcpp.12878. Epub 2018 Mar 1.


Longitudinal analysis strategies for modelling epigenetic trajectories.

Staley JR, Suderman M, Simpkin AJ, Gaunt TR, Heron J, Relton CL, Tilling K.

Int J Epidemiol. 2018 Apr 1;47(2):516-525. doi: 10.1093/ije/dyy012.


Developing new age-specific prostate-specific antigen thresholds for testing for prostate cancer.

Gilbert R, Tilling K, Martin RM, Lane JA, Davis M, Hamdy FC, Neal DE, Donovan JL, Metcalfe C.

Cancer Causes Control. 2018 Mar;29(3):383-388. doi: 10.1007/s10552-018-1014-3. Epub 2018 Feb 16.


The impact of parity on life course blood pressure trajectories: the HUNT study in Norway.

Haug EB, Horn J, Markovitz AR, Fraser A, Macdonald-Wallis C, Tilling K, Romundstad PR, Rich-Edwards JW, Åsvold BO.

Eur J Epidemiol. 2018 Aug;33(8):751-761. doi: 10.1007/s10654-018-0358-z. Epub 2018 Jan 24. Erratum in: Eur J Epidemiol. 2018 Jul 6;:.

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