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Items: 6


The tarantula toxin GxTx detains K+ channel gating charges in their resting conformation.

Tilley DC, Angueyra JM, Eum KS, Kim H, Chao LH, Peng AW, Sack JT.

J Gen Physiol. 2018 Nov 5. pii: jgp.201812213. doi: 10.1085/jgp.201812213. [Epub ahead of print]


Azide-Alkyne Click Conjugation on Quantum Dots by Selective Copper Coordination.

Mann VR, Powers AS, Tilley DC, Sack JT, Cohen BE.

ACS Nano. 2018 May 22;12(5):4469-4477. doi: 10.1021/acsnano.8b00575. Epub 2018 Apr 4.


An Integrated Framework Advancing Membrane Protein Modeling and Design.

Alford RF, Koehler Leman J, Weitzner BD, Duran AM, Tilley DC, Elazar A, Gray JJ.

PLoS Comput Biol. 2015 Sep 1;11(9):e1004398. doi: 10.1371/journal.pcbi.1004398. eCollection 2015 Sep.


What keeps Kv channels small? The molecular physiology of modesty.

Sack JT, Tilley DC.

J Gen Physiol. 2015 Aug;146(2):123-7. doi: 10.1085/jgp.201511469. No abstract available.


Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels.

Gupta K, Zamanian M, Bae C, Milescu M, Krepkiy D, Tilley DC, Sack JT, Yarov-Yarovoy V, Kim JI, Swartz KJ.

Elife. 2015 May 7;4:e06774. doi: 10.7554/eLife.06774.


Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells.

Tilley DC, Eum KS, Fletcher-Taylor S, Austin DC, Dupré C, Patrón LA, Garcia RL, Lam K, Yarov-Yarovoy V, Cohen BE, Sack JT.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4789-96. doi: 10.1073/pnas.1406876111. Epub 2014 Oct 20.

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