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Items: 17

1.

Persistence of circulating endothelial microparticles in COPD despite smoking cessation.

Strulovici-Barel Y, Staudt MR, Krause A, Gordon C, Tilley AE, Harvey BG, Kaner RJ, Hollmann C, Mezey JG, Bitter H, Pillai SG, Hilton H, Wolff G, Stevenson CS, Visvanathan S, Fine JS, Crystal RG.

Thorax. 2016 Dec;71(12):1137-1144. doi: 10.1136/thoraxjnl-2015-208274. Epub 2016 Jul 26.

2.

Cigarette Smoking Induces Changes in Airway Epithelial Expression of Genes Associated with Monogenic Lung Disorders.

Tilley AE, Staudt MR, Salit J, Van de Graaf B, Strulovici-Barel Y, Kaner RJ, Vincent T, Agosto-Perez F, Mezey JG, Raby BA, Crystal RG.

Am J Respir Crit Care Med. 2016 Jan 15;193(2):215-7. doi: 10.1164/rccm.201412-2290LE. No abstract available.

3.

Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.

Wang G, Wang R, Strulovici-Barel Y, Salit J, Staudt MR, Ahmed J, Tilley AE, Yee-Levin J, Hollmann C, Harvey BG, Kaner RJ, Mezey JG, Sridhar S, Pillai SG, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine JS, Stevenson CS, Crystal RG.

PLoS One. 2015 Apr 17;10(4):e0120824. doi: 10.1371/journal.pone.0120824. eCollection 2015.

4.

Cilia dysfunction in lung disease.

Tilley AE, Walters MS, Shaykhiev R, Crystal RG.

Annu Rev Physiol. 2015;77:379-406. doi: 10.1146/annurev-physiol-021014-071931. Epub 2014 Oct 29. Review.

5.

Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.

Staudt MR, Buro-Auriemma LJ, Walters MS, Salit J, Vincent T, Shaykhiev R, Mezey JG, Tilley AE, Kaner RJ, Ho MW, Crystal RG.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):955-8. doi: 10.1164/rccm.201406-1167LE. No abstract available.

6.

Smoking accelerates aging of the small airway epithelium.

Walters MS, De BP, Salit J, Buro-Auriemma LJ, Wilson T, Rogalski AM, Lief L, Hackett NR, Staudt MR, Tilley AE, Harvey BG, Kaner RJ, Mezey JG, Ashbridge B, Moore MA, Crystal RG.

Respir Res. 2014 Sep 24;15:94. doi: 10.1186/s12931-014-0094-1.

7.

FOXJ1 prevents cilia growth inhibition by cigarette smoke in human airway epithelium in vitro.

Brekman A, Walters MS, Tilley AE, Crystal RG.

Am J Respir Cell Mol Biol. 2014 Nov;51(5):688-700. doi: 10.1165/rcmb.2013-0363OC.

8.

Intraflagellar transport gene expression associated with short cilia in smoking and COPD.

Hessel J, Heldrich J, Fuller J, Staudt MR, Radisch S, Hollmann C, Harvey BG, Kaner RJ, Salit J, Yee-Levin J, Sridhar S, Pillai S, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine J, Stevenson CS, Crystal RG, Tilley AE.

PLoS One. 2014 Jan 20;9(1):e85453. doi: 10.1371/journal.pone.0085453. eCollection 2014.

9.

High correlation of the response of upper and lower lobe small airway epithelium to smoking.

Harvey BG, Strulovici-Barel Y, Vincent TL, Mezey JG, Raviram R, Gordon C, Salit J, Tilley AE, Chung A, Sanders A, Crystal RG.

PLoS One. 2013 Sep 9;8(9):e72669. doi: 10.1371/journal.pone.0072669. eCollection 2013.

10.

Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokers.

Wang G, Xu Z, Wang R, Al-Hijji M, Salit J, Strulovici-Barel Y, Tilley AE, Mezey JG, Crystal RG.

BMC Med Genomics. 2012 Jun 7;5:21. doi: 10.1186/1755-8794-5-21.

11.

Biologic phenotyping of the human small airway epithelial response to cigarette smoking.

Tilley AE, O'Connor TP, Hackett NR, Strulovici-Barel Y, Salit J, Amoroso N, Zhou XK, Raman T, Omberg L, Clark A, Mezey J, Crystal RG.

PLoS One. 2011;6(7):e22798. doi: 10.1371/journal.pone.0022798. Epub 2011 Jul 28.

12.

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia.

Pezzulo AA, Starner TD, Scheetz TE, Traver GL, Tilley AE, Harvey BG, Crystal RG, McCray PB Jr, Zabner J.

Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L25-31. doi: 10.1152/ajplung.00256.2010. Epub 2010 Oct 22.

13.

Threshold of biologic responses of the small airway epithelium to low levels of tobacco smoke.

Strulovici-Barel Y, Omberg L, O'Mahony M, Gordon C, Hollmann C, Tilley AE, Salit J, Mezey J, Harvey BG, Crystal RG.

Am J Respir Crit Care Med. 2010 Dec 15;182(12):1524-32. doi: 10.1164/rccm.201002-0294OC. Epub 2010 Aug 6.

14.

Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome?

Dvorak A, Tilley AE, Shaykhiev R, Wang R, Crystal RG.

Am J Respir Cell Mol Biol. 2011 Apr;44(4):465-73. doi: 10.1165/rcmb.2009-0453OC. Epub 2010 Jun 4.

15.

Trachea epithelium as a "canary" for cigarette smoking-induced biologic phenotype of the small airway epithelium.

Turetz ML, O'Connor TP, Tilley AE, Strulovici-Barel Y, Salit J, Dang D, Teater M, Mezey J, Clark AG, Crystal RG.

Clin Transl Sci. 2009 Aug;2(4):260-72. doi: 10.1111/j.1752-8062.2009.00129.x.

16.

Smoking is associated with shortened airway cilia.

Leopold PL, O'Mahony MJ, Lian XJ, Tilley AE, Harvey BG, Crystal RG.

PLoS One. 2009 Dec 16;4(12):e8157. doi: 10.1371/journal.pone.0008157.

17.

Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.

Tilley AE, Harvey BG, Heguy A, Hackett NR, Wang R, O'Connor TP, Crystal RG.

Am J Respir Crit Care Med. 2009 Mar 15;179(6):457-66. doi: 10.1164/rccm.200705-795OC. Epub 2008 Dec 23.

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