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Items: 30

1.

Mutational analysis of the Aspergillus ambient pH receptor PalH underscores its potential as a target for antifungal compounds.

Lucena-Agell D, Hervás-Aguilar A, Múnera-Huertas T, Pougovkina O, Rudnicka J, Galindo A, Tilburn J, Arst HN Jr, Peñalva MA.

Mol Microbiol. 2016 Sep;101(6):982-1002. doi: 10.1111/mmi.13438. Epub 2016 Jul 15.

2.

Refining the pH response in Aspergillus nidulans: a modulatory triad involving PacX, a novel zinc binuclear cluster protein.

Bussink HJ, Bignell EM, Múnera-Huertas T, Lucena-Agell D, Scazzocchio C, Espeso EA, Bertuzzi M, Rudnicka J, Negrete-Urtasun S, Peñas-Parilla MM, Rainbow L, Peñalva MÁ, Arst HN Jr, Tilburn J.

Mol Microbiol. 2015 Dec;98(6):1051-72. doi: 10.1111/mmi.13173. Epub 2015 Oct 16.

3.

Ambient pH gene regulation in fungi: making connections.

Peñalva MA, Tilburn J, Bignell E, Arst HN Jr.

Trends Microbiol. 2008 Jun;16(6):291-300. doi: 10.1016/j.tim.2008.03.006. Epub 2008 May 3. Review.

PMID:
18457952
4.

Establishment of the ambient pH signaling complex in Aspergillus nidulans: PalI assists plasma membrane localization of PalH.

Calcagno-Pizarelli AM, Negrete-Urtasun S, Denison SH, Rudnicka JD, Bussink HJ, Múnera-Huertas T, Stanton L, Hervás-Aguilar A, Espeso EA, Tilburn J, Arst HN Jr, Peñalva MA.

Eukaryot Cell. 2007 Dec;6(12):2365-75. Epub 2007 Oct 19.

5.

Evidence for the direct involvement of the proteasome in the proteolytic processing of the Aspergillus nidulans zinc finger transcription factor PacC.

Hervás-Aguilar A, Rodríguez JM, Tilburn J, Arst HN Jr, Peñalva MA.

J Biol Chem. 2007 Nov 30;282(48):34735-47. Epub 2007 Oct 1.

6.

PalC, one of two Bro1 domain proteins in the fungal pH signalling pathway, localizes to cortical structures and binds Vps32.

Galindo A, Hervás-Aguilar A, Rodríguez-Galán O, Vincent O, Arst HN Jr, Tilburn J, Peñalva MA.

Traffic. 2007 Oct;8(10):1346-64. Epub 2007 Aug 13.

7.

Further characterization of the signaling proteolysis step in the Aspergillus nidulans pH signal transduction pathway.

Peñas MM, Hervás-Aguilar A, Múnera-Huertas T, Reoyo E, Peñalva MA, Arst HN Jr, Tilburn J.

Eukaryot Cell. 2007 Jun;6(6):960-70. Epub 2007 Apr 6.

8.

Nonsense-mediated mRNA decay mutation in Aspergillus nidulans.

Morozov IY, Negrete-Urtasun S, Tilburn J, Jansen CA, Caddick MX, Arst HN Jr.

Eukaryot Cell. 2006 Nov;5(11):1838-46. Epub 2006 Sep 8.

9.
10.

Mutational analysis of the pH signal transduction component PalC of Aspergillus nidulans supports distant similarity to BRO1 domain family members.

Tilburn J, Sánchez-Ferrero JC, Reoyo E, Arst HN Jr, Peñalva MA.

Genetics. 2005 Sep;171(1):393-401. Epub 2005 Jun 8.

11.

Overlap of nuclear localisation signal and specific DNA-binding residues within the zinc finger domain of PacC.

Fernández-Martínez J, Brown CV, Díez E, Tilburn J, Arst HN Jr, Peñalva MA, Espeso EA.

J Mol Biol. 2003 Dec 5;334(4):667-84.

PMID:
14636595
12.

YPXL/I is a protein interaction motif recognized by aspergillus PalA and its human homologue, AIP1/Alix.

Vincent O, Rainbow L, Tilburn J, Arst HN Jr, Peñalva MA.

Mol Cell Biol. 2003 Mar;23(5):1647-55.

13.

Activation of the Aspergillus PacC zinc finger transcription factor requires two proteolytic steps.

Díez E, Alvaro J, Espeso EA, Rainbow L, Suárez T, Tilburn J, Arst HN Jr, Peñalva MA.

EMBO J. 2002 Mar 15;21(6):1350-9.

14.

Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in Saccharomyces are homologous Addendum.

Denison SH, Negrete-Urtasun S, Mingot JM, Tilburn J, Mayer WA, Goel A, Espeso EA, Peñalva MA, Arst HN.

Mol Microbiol. 2001 Jan;39(1):211. No abstract available.

15.

On how a transcription factor can avoid its proteolytic activation in the absence of signal transduction.

Espeso EA, Roncal T, Díez E, Rainbow L, Bignell E, Alvaro J, Suárez T, Denison SH, Tilburn J, Arst HN Jr, Peñalva MA.

EMBO J. 2000 Feb 15;19(4):719-28. Erratum in: EMBO J 2000 May 15;19(10):2391.

16.

Ambient pH signal transduction in Aspergillus: completion of gene characterization.

Negrete-Urtasun S, Reiter W, Diez E, Denison SH, Tilburn J, Espeso EA, Peñalva MA, Arst HN Jr.

Mol Microbiol. 1999 Sep;33(5):994-1003.

17.

The multiply-regulated gabA gene encoding the GABA permease of Aspergillus nidulans: a score of exons.

Hutchings H, Stahmann KP, Roels S, Espeso EA, Timberlake WE, Arst HN Jr, Tilburn J.

Mol Microbiol. 1999 May;32(3):557-68.

18.

Specificity determinants of proteolytic processing of Aspergillus PacC transcription factor are remote from the processing site, and processing occurs in yeast if pH signalling is bypassed.

Mingot JM, Tilburn J, Diez E, Bignell E, Orejas M, Widdick DA, Sarkar S, Brown CV, Caddick MX, Espeso EA, Arst HN Jr, Peñalva MA.

Mol Cell Biol. 1999 Feb;19(2):1390-400.

19.

Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in saccharomyces are homologous.

Denison SH, Negrete-Urtasun S, Mingot JM, Tilburn J, Mayer WA, Goel A, Espeso EA, Peñalva MA, Arst HN Jr.

Mol Microbiol. 1998 Oct;30(2):259-64. Erratum in: Mol Microbiol 2001 Jan;39(1):211.

20.

Specific DNA recognition by the Aspergillus nidulans three zinc finger transcription factor PacC.

Espeso EA, Tilburn J, Sánchez-Pulido L, Brown CV, Valencia A, Arst HN Jr, Peñalva MA.

J Mol Biol. 1997 Dec 12;274(4):466-80.

PMID:
9417928
21.

Regulation of gene expression by ambient pH in Aspergillus: genes expressed at acid pH.

Sarkar S, Caddick MX, Bignell E, Tilburn J, Arst HN Jr.

Biochem Soc Trans. 1996 May;24(2):360-3. Review. No abstract available. Erratum in: Biochem Soc Trans. 2004 Dec;32(Pt 6):1133.

PMID:
8736763
22.

Identification, cloning and analysis of the Aspergillus niger gene pacC, a wide domain regulatory gene responsive to ambient pH.

MacCabe AP, Van den Hombergh JP, Tilburn J, Arst HN Jr, Visser J.

Mol Gen Genet. 1996 Feb 25;250(3):367-74.

PMID:
8602152
23.

Activation of the Aspergillus PacC transcription factor in response to alkaline ambient pH requires proteolysis of the carboxy-terminal moiety.

Orejas M, Espeso EA, Tilburn J, Sarkar S, Arst HN Jr, Peñalva MA.

Genes Dev. 1995 Jul 1;9(13):1622-32.

24.

The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid- and alkaline-expressed genes by ambient pH.

Tilburn J, Sarkar S, Widdick DA, Espeso EA, Orejas M, Mungroo J, Peñalva MA, Arst HN Jr.

EMBO J. 1995 Feb 15;14(4):779-90.

25.

Two new genes involved in signalling ambient pH in Aspergillus nidulans.

Arst HN Jr, Bignell E, Tilburn J.

Mol Gen Genet. 1994 Dec 15;245(6):787-90.

PMID:
7830727
26.

pH regulation is a major determinant in expression of a fungal penicillin biosynthetic gene.

Espeso EA, Tilburn J, Arst HN Jr, Peñalva MA.

EMBO J. 1993 Oct;12(10):3947-56.

28.

pH regulation of penicillin production in Aspergillus nidulans.

Shah AJ, Tilburn J, Adlard MW, Arst HN Jr.

FEMS Microbiol Lett. 1991 Jan 15;61(2-3):209-12.

PMID:
2037230
29.

Insertional inactivation and cloning of the wA gene of Aspergillus nidulans.

Tilburn J, Roussel F, Scazzocchio C.

Genetics. 1990 Sep;126(1):81-90.

30.

Transformation by integration in Aspergillus nidulans.

Tilburn J, Scazzocchio C, Taylor GG, Zabicky-Zissman JH, Lockington RA, Davies RW.

Gene. 1983 Dec;26(2-3):205-21.

PMID:
6368319

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