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Items: 1 to 50 of 90

1.

Lidocaine and carbamazepine inhibit while phenytoin and lamotrigine paradoxically enhance the insect neuromuscular transmission.

Fedorova IM, Tikhonov DB.

Invert Neurosci. 2019 Feb 8;19(1):4. doi: 10.1007/s10158-019-0224-z.

PMID:
30734144
2.

Batrachotoxin acts as a stent to hold open homotetrameric prokaryotic voltage-gated sodium channels.

Finol-Urdaneta RK, McArthur JR, Goldschen-Ohm MP, Gaudet R, Tikhonov DB, Zhorov BS, French RJ.

J Gen Physiol. 2019 Feb 4;151(2):186-199. doi: 10.1085/jgp.201812278. Epub 2018 Dec 26.

3.

Multiple modes of action of hydrophobic amines and their guanidine analogues on ASIC1a.

Shteinikov VY, Barygin OI, Gmiro VE, Tikhonov DB.

Eur J Pharmacol. 2019 Feb 5;844:183-194. doi: 10.1016/j.ejphar.2018.12.024. Epub 2018 Dec 14.

PMID:
30557561
4.

Modulation of Proton-Gated Channels by Antidepressants.

Nikolaev MV, Komarova MS, Tikhonova TB, Korosteleva AS, Potapjeva NN, Tikhonov DB.

ACS Chem Neurosci. 2019 Mar 20;10(3):1636-1648. doi: 10.1021/acschemneuro.8b00560. Epub 2018 Dec 5.

PMID:
30475579
5.

Predicting Structural Details of the Sodium Channel Pore Basing on Animal Toxin Studies.

Tikhonov DB, Zhorov BS.

Front Pharmacol. 2018 Aug 7;9:880. doi: 10.3389/fphar.2018.00880. eCollection 2018. Review.

6.

Optical control of L-type Ca2+ channels using a diltiazem photoswitch.

Fehrentz T, Huber FME, Hartrampf N, Bruegmann T, Frank JA, Fine NHF, Malan D, Danzl JG, Tikhonov DB, Sumser M, Sasse P, Hodson DJ, Zhorov BS, Klöcker N, Trauner D.

Nat Chem Biol. 2018 Aug;14(8):764-767. doi: 10.1038/s41589-018-0090-8. Epub 2018 Jul 16.

PMID:
30013061
7.

Mutational analysis of state-dependent contacts in the pore module of eukaryotic sodium channels.

Du Y, Tikhonov DB, Nomura Y, Dong K, Zhorov BS.

Arch Biochem Biophys. 2018 Aug 15;652:59-70. doi: 10.1016/j.abb.2018.06.008. Epub 2018 Jun 21.

PMID:
29936083
8.

Complex action of tyramine, tryptamine and histamine on native and recombinant ASICs.

Barygin OI, Komarova MS, Tikhonova TB, Korosteleva AS, Nikolaev MV, Magazanik LG, Tikhonov DB.

Channels (Austin). 2017 Nov 2;11(6):648-659. doi: 10.1080/19336950.2017.1394557. Epub 2017 Nov 13.

9.

Conservation and variability of the pore-lining helices in P-loop channels.

Tikhonov DB, Zhorov BS.

Channels (Austin). 2017 Nov 2;11(6):660-672. doi: 10.1080/19336950.2017.1395536. Epub 2017 Dec 1.

10.

Potentiation and Block of ASIC1a by Memantine.

Shteinikov VY, Tikhonova TB, Korkosh VS, Tikhonov DB.

Cell Mol Neurobiol. 2018 May;38(4):869-881. doi: 10.1007/s10571-017-0561-6. Epub 2017 Oct 20.

PMID:
29058095
11.

Ligands of histamine receptors modulate acid-sensing ion channels.

Shteinikov VY, Korosteleva AS, Tikhonova TB, Potapieva NN, Tikhonov DB.

Biochem Biophys Res Commun. 2017 Sep 2;490(4):1314-1318. doi: 10.1016/j.bbrc.2017.07.019. Epub 2017 Jul 5.

PMID:
28688766
12.

TRPV1 activation power can switch an action mode for its polypeptide ligands.

Nikolaev MV, Dorofeeva NA, Komarova MS, Korolkova YV, Andreev YA, Mosharova IV, Grishin EV, Tikhonov DB, Kozlov SA.

PLoS One. 2017 May 5;12(5):e0177077. doi: 10.1371/journal.pone.0177077. eCollection 2017.

13.

Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.

Tikhonov DB, Zhorov BS.

J Gen Physiol. 2017 Apr 3;149(4):465-481. doi: 10.1085/jgp.201611668. Epub 2017 Mar 3.

14.

Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics.

Barygin OI, Nagaeva EI, Tikhonov DB, Belinskaya DA, Vanchakova NP, Shestakova NN.

Brain Res. 2017 Apr 1;1660:58-66. doi: 10.1016/j.brainres.2017.01.028. Epub 2017 Feb 3.

PMID:
28167075
15.

Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels.

Zhorov BS, Tikhonov DB.

Curr Top Membr. 2016;78:117-44. doi: 10.1016/bs.ctm.2015.12.001. Epub 2016 Mar 14.

PMID:
27586283
16.

Histamine selectively potentiates acid-sensing ion channel 1a.

Nagaeva EI, Tikhonova TB, Magazanik LG, Tikhonov DB.

Neurosci Lett. 2016 Oct 6;632:136-40. doi: 10.1016/j.neulet.2016.08.047. Epub 2016 Aug 27.

PMID:
27574729
17.

Determinants of action of hydrophobic amines on ASIC1a and ASIC2a.

Nagaeva EI, Potapieva NN, Nikolaev MV, Gmiro VE, Magazanik LG, Tikhonov DB.

Eur J Pharmacol. 2016 Oct 5;788:75-83. doi: 10.1016/j.ejphar.2016.06.013. Epub 2016 Jun 8.

PMID:
27288880
18.

[MOLECULAR EVOLUTION OF ION CHANNELS: AMINO ACID SEQUENCES AND 3D STRUCTURES].

Korkosh VS, Zhorov BS, Tikhonov DB.

Zh Evol Biokhim Fiziol. 2016 Jan-Feb;52(1):26-33. Russian.

PMID:
27220237
19.

Modeling interactions between blocking and permeant cations in the NavMs channel.

Korkosh VS, Zhorov BS, Tikhonov DB.

Eur J Pharmacol. 2016 Jun 5;780:188-93. doi: 10.1016/j.ejphar.2016.03.048. Epub 2016 Mar 26.

PMID:
27020546
20.

Analysis of inter-residue contacts reveals folding stabilizers in P-loops of potassium, sodium, and TRPV channels.

Korkosh VS, Zhorov BS, Tikhonov DB.

Eur Biophys J. 2016 May;45(4):321-9. doi: 10.1007/s00249-015-1098-6. Epub 2015 Dec 8.

PMID:
26646260
21.

ω-Tbo-IT1-New Inhibitor of Insect Calcium Channels Isolated from Spider Venom.

Mikov AN, Fedorova IM, Potapieva NN, Maleeva EE, Andreev YA, Zaitsev AV, Kim KK, Bocharov EV, Bozin TN, Altukhov DA, Lipkin AV, Kozlov SA, Tikhonov DB, Grishin EV.

Sci Rep. 2015 Nov 27;5:17232. doi: 10.1038/srep17232.

22.

Statistical models suggest presence of two distinct subpopulations of miniature EPSCs in fast-spiking interneurons of rat prefrontal cortex.

Malkin SL, Kim KK, Tikhonov DB, Magazanik LG, Zaitsev AV.

Neuroscience. 2015 Aug 20;301:508-19. doi: 10.1016/j.neuroscience.2015.06.034. Epub 2015 Jun 26.

PMID:
26118990
23.

The Effect of Hydrophobic Monoamines on Acid-Sensing Ion Channels ASIC1B.

Nagaeva EI, Potapieva NN, Tikhonov DB.

Acta Naturae. 2015 Apr-Jun;7(2):95-101.

24.

[Properties of spontaneous and miniature excitatory postsynaptic currents of rat prefrontal cortex neurons].

Malkin SL, Kim KKh, Tikhonov DB, Zaitsev AV.

Zh Evol Biokhim Fiziol. 2014 Nov-Dec;50(6):440-6. Russian.

PMID:
25782285
25.

Non-classical mechanism of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor channel block by fluoxetine.

Barygin OI, Komarova MS, Tikhonova TB, Tikhonov DB.

Eur J Neurosci. 2015 Apr;41(7):869-77. doi: 10.1111/ejn.12817. Epub 2014 Dec 31.

PMID:
25557871
26.

Monoamine NMDA receptor channel blockers inhibit and potentiate native and recombinant proton-gated ion channels.

Tikhonova TB, Nagaeva EI, Barygin OI, Potapieva NN, Bolshakov KV, Tikhonov DB.

Neuropharmacology. 2015 Feb;89:1-10. doi: 10.1016/j.neuropharm.2014.08.018. Epub 2014 Sep 6.

PMID:
25196733
28.

The effects of conformational constraints in the polyamine moiety of philanthotoxins on AMPAR inhibition.

Franzyk H, Grzeskowiak JW, Tikhonov DB, Jaroszewski JW, Mellor IR.

ChemMedChem. 2014 Aug;9(8):1725-31. doi: 10.1002/cmdc.201402109. Epub 2014 Jul 8.

PMID:
25044789
29.

State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels.

Tikhonov DB, Bruhova I, Garden DP, Zhorov BS.

Pflugers Arch. 2015 Feb;467(2):253-66. doi: 10.1007/s00424-014-1508-0. Epub 2014 Apr 15.

PMID:
24728659
30.

Homology modeling of Kv1.5 channel block by cationic and electroneutral ligands.

Tikhonov DB, Zhorov BS.

Biochim Biophys Acta. 2014 Mar;1838(3):978-87. doi: 10.1016/j.bbamem.2013.11.019. Epub 2013 Dec 5.

31.

Ligand action on sodium, potassium, and calcium channels: role of permeant ions.

Zhorov BS, Tikhonov DB.

Trends Pharmacol Sci. 2013 Mar;34(3):154-61. doi: 10.1016/j.tips.2013.01.002. Epub 2013 Feb 1.

PMID:
23375737
32.

Architecture and pore block of eukaryotic voltage-gated sodium channels in view of NavAb bacterial sodium channel structure.

Tikhonov DB, Zhorov BS.

Mol Pharmacol. 2012 Jul;82(1):97-104. doi: 10.1124/mol.112.078212. Epub 2012 Apr 13.

PMID:
22505150
33.

Influence of external magnesium ions on the NMDA receptor channel block by different types of organic cations.

Nikolaev MV, Magazanik LG, Tikhonov DB.

Neuropharmacology. 2012 Apr;62(5-6):2078-85. doi: 10.1016/j.neuropharm.2011.12.029. Epub 2012 Jan 12.

PMID:
22261381
34.

Argiotoxin in the closed AMPA receptor channel: experimental and modeling study.

Barygin OI, Grishin EV, Tikhonov DB.

Biochemistry. 2011 Sep 27;50(38):8213-20. doi: 10.1021/bi200617v. Epub 2011 Aug 29.

PMID:
21842876
35.

Specific mechanism of use-dependent channel block of calcium-permeable AMPA receptors provides activity-dependent inhibition of glutamatergic neurotransmission.

Zaitsev AV, Kim KK, Fedorova IM, Dorofeeva NA, Magazanik LG, Tikhonov DB.

J Physiol. 2011 Apr 1;589(Pt 7):1587-601. doi: 10.1113/jphysiol.2011.204362. Erratum in: J Physiol. 2011 Aug 15;589(Pt 16):4081.

36.

Possible roles of exceptionally conserved residues around the selectivity filters of sodium and calcium channels.

Tikhonov DB, Zhorov BS.

J Biol Chem. 2011 Jan 28;286(4):2998-3006. doi: 10.1074/jbc.M110.175406. Epub 2010 Nov 16.

37.

[The diversity of mechanisms of the ion channels blockade as a way towards designing new pharmacological agents].

Tikhonov DB, Magazanik LG.

Ross Fiziol Zh Im I M Sechenova. 2010 Jul;96(7):726-39. Review. Russian.

PMID:
20973176
38.

Voltage-dependent and -independent block of α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor channels.

Barygin OI, Luchkina NV, Tikhonov DB.

J Neurochem. 2010 Dec;115(6):1621-32. doi: 10.1111/j.1471-4159.2010.07068.x. Epub 2010 Nov 19.

39.

[The effect of the environment ion composition upon the blockade of the AMPA receptor channels].

Tikhonova TB, Magazanik LG, Tikhonov DB.

Ross Fiziol Zh Im I M Sechenova. 2010 Mar;96(3):237-46. Russian.

PMID:
20535994
40.

Investigation of structure-activity relationships in organophosphates-cholinesterase interaction using docking analysis.

Moralev SN, Tikhonov DB.

Chem Biol Interact. 2010 Sep 6;187(1-3):153-6. doi: 10.1016/j.cbi.2010.03.039. Epub 2010 Mar 27.

PMID:
20347727
41.

Structural modeling of calcium binding in the selectivity filter of the L-type calcium channel.

Cheng RC, Tikhonov DB, Zhorov BS.

Eur Biophys J. 2010 Apr;39(5):839-53. doi: 10.1007/s00249-009-0574-2. Epub 2010 Jan 7.

PMID:
20054687
42.

Origin and molecular evolution of ionotropic glutamate receptors.

Tikhonov DB, Magazanik LG.

Neurosci Behav Physiol. 2009 Oct;39(8):763-73. doi: 10.1007/s11055-009-9195-6. Epub 2009 Sep 23. Review.

PMID:
19779829
43.

Structural model for phenylalkylamine binding to L-type calcium channels.

Cheng RC, Tikhonov DB, Zhorov BS.

J Biol Chem. 2009 Oct 9;284(41):28332-42. doi: 10.1074/jbc.M109.027326. Epub 2009 Aug 21.

44.

Structural model for dihydropyridine binding to L-type calcium channels.

Tikhonov DB, Zhorov BS.

J Biol Chem. 2009 Jul 10;284(28):19006-17. doi: 10.1074/jbc.M109.011296. Epub 2009 May 5.

45.

[Ion channels of glutamate receptors of nerve-muscle junction of the fly larva Calliphora vicina demonstrate a high structural homology with vertebrate AMPA-channels].

Fedorova IM, gmiro VE, Magazanik LG, Tikhonov DB.

Zh Evol Biokhim Fiziol. 2008 Nov-Dec;44(6):556-62. Russian.

PMID:
19198155
46.

Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors.

Nelson JK, Frølund SU, Tikhonov DB, Kristensen AS, Strømgaard K.

Angew Chem Int Ed Engl. 2009;48(17):3087-91. doi: 10.1002/anie.200805426.

PMID:
19152392
47.

Common binding site for externally and internally applied AMPA receptor channel blockers.

Tikhonova TB, Tikhonov DB, Magazanik LG.

J Mol Neurosci. 2009 Sep;39(1-2):169-74. doi: 10.1007/s12031-008-9172-5. Epub 2009 Jan 13.

PMID:
19140031
48.

Blockade of NMDA receptor channels by 9-aminoacridine and its derivatives.

Barygin OI, Gmiro VE, Kim KKh, Magazanik LG, Tikhonov DB.

Neurosci Lett. 2009 Feb 13;451(1):29-33. doi: 10.1016/j.neulet.2008.12.036. Epub 2008 Dec 24.

PMID:
19111901
49.

[The origin and molecular evolution of ionotropic glutamate receptors].

Tikhonov DB, Magazanik LG.

Ross Fiziol Zh Im I M Sechenova. 2008 Sep;94(9):989-1004. Review. Russian.

PMID:
18953990
50.

Characterization of ionotropic glutamate receptors in insect neuro-muscular junction.

Fedorova IM, Magazanik LG, Tikhonov DB.

Comp Biochem Physiol C Toxicol Pharmacol. 2009 Apr;149(3):275-80. doi: 10.1016/j.cbpc.2008.07.010. Epub 2008 Jul 31.

PMID:
18723120

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