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Items: 50

1.

Diagnostic Power of DNA Methylation Classifiers for Early Detection of Cancer.

Roy D, Tiirikainen M.

Trends Cancer. 2020 Feb;6(2):78-81. doi: 10.1016/j.trecan.2019.12.006. Epub 2020 Feb 3.

PMID:
32061307
2.

Ex vivo culture of lesional psoriasis skin for pharmacological testing.

Tiirikainen ML, Woetmann A, Norsgaard H, Santamaria-Babí LF, Lovato P.

J Dermatol Sci. 2020 Feb;97(2):109-116. doi: 10.1016/j.jdermsci.2019.12.010. Epub 2019 Dec 27.

3.

Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice.

Seale LA, Khadka VS, Menor M, Xie G, Watanabe LM, Sasuclark A, Guirguis K, Ha HY, Hashimoto AC, Peplowska K, Tiirikainen M, Jia W, Berry MJ, Deng Y.

Nutrients. 2019 Oct 26;11(11). pii: E2584. doi: 10.3390/nu11112584.

4.

Low expression of WWC1, a tumor suppressor gene, is associated with aggressive breast cancer and poor survival outcome.

Wang Z, Katsaros D, Biglia N, Shen Y, Fu Y, Tiirikainen M, Yu H.

FEBS Open Bio. 2019 Jul;9(7):1270-1280. doi: 10.1002/2211-5463.12659. Epub 2019 Jun 1.

5.

Transcriptomics Associates Molecular Features with 18F-Fluorocholine PET/CT Imaging Phenotype and Its Potential Relationship to Survival in Hepatocellular Carcinoma.

Kwee SA, Tiirikainen M, Sato MM, Acoba JD, Wei R, Jia W, Le Marchand L, Wong LL.

Cancer Res. 2019 Apr 1;79(7):1696-1704. doi: 10.1158/0008-5472.CAN-18-3837. Epub 2019 Feb 13.

6.

Methylation of imprinted IGF2 regions is associated with total, visceral, and hepatic adiposity in postmenopausal women.

Song MA, Ernst T, Tiirikainen M, Tost J, Wilkens LR, Chang L, Kolonel LN, Le Marchand L, Lim U.

Epigenetics. 2018;13(8):858-865. doi: 10.1080/15592294.2018.1518100. Epub 2018 Oct 2.

7.

Association of internal smoking dose with blood DNA methylation in three racial/ethnic populations.

Park SL, Patel YM, Loo LWM, Mullen DJ, Offringa IA, Maunakea A, Stram DO, Siegmund K, Murphy SE, Tiirikainen M, Le Marchand L.

Clin Epigenetics. 2018 Aug 23;10(1):110. doi: 10.1186/s13148-018-0543-7.

8.

Influence of UGT2B10 Genotype on Urinary Excretion of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol- N-glucuronide by African American Smokers.

Murphy SE, von Weymarn LB, Parenteau M, Stepanov I, Tiirikainen M, LeMarchand L, Park SL.

Chem Res Toxicol. 2018 Mar 19;31(3):168-175. doi: 10.1021/acs.chemrestox.7b00264. Epub 2018 Feb 28.

9.

Clinical and molecular sub-classification of hepatocellular carcinoma relative to alpha-fetoprotein level in an Asia-Pacific island cohort.

Nishioka ST, Sato MM, Wong LL, Tiirikainen M, Kwee SA.

Hepatoma Res. 2018;4. pii: 1. doi: 10.20517/2394-5079.2017.46. Epub 2018 Jan 12.

10.

Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.

Donlon TA, Morris BJ, Chen R, Masaki KH, Allsopp RC, Willcox DC, Tiirikainen M, Willcox BJ.

J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1459-1464. doi: 10.1093/gerona/glx247.

11.

Genetic Determinants of 1,3-Butadiene Metabolism and Detoxification in Three Populations of Smokers with Different Risks of Lung Cancer.

Boldry EJ, Patel YM, Kotapati S, Esades A, Park SL, Tiirikainen M, Stram DO, Le Marchand L, Tretyakova N.

Cancer Epidemiol Biomarkers Prev. 2017 Jul;26(7):1034-1042. doi: 10.1158/1055-9965.EPI-16-0838. Epub 2017 Mar 14.

12.

Time Series miRNA-mRNA integrated analysis reveals critical miRNAs and targets in macrophage polarization.

Lu L, McCurdy S, Huang S, Zhu X, Peplowska K, Tiirikainen M, Boisvert WA, Garmire LX.

Sci Rep. 2016 Dec 16;6:37446. doi: 10.1038/srep37446.

13.

Joint analysis of multiple high-dimensional data types using sparse matrix approximations of rank-1 with applications to ovarian and liver cancer.

Okimoto G, Zeinalzadeh A, Wenska T, Loomis M, Nation JB, Fabre T, Tiirikainen M, Hernandez B, Chan O, Wong L, Kwee S.

BioData Min. 2016 Jul 29;9:24. doi: 10.1186/s13040-016-0103-7. eCollection 2016.

14.

Pan-Cancer Analyses Reveal Long Intergenic Non-Coding RNAs Relevant to Tumor Diagnosis, Subtyping and Prognosis.

Ching T, Peplowska K, Huang S, Zhu X, Shen Y, Molnar J, Yu H, Tiirikainen M, Fogelgren B, Fan R, Garmire LX.

EBioMedicine. 2016 May;7:62-72. doi: 10.1016/j.ebiom.2016.03.023. Epub 2016 Mar 19.

15.

Comparison of genome-scale DNA methylation profiles in hepatocellular carcinoma by viral status.

Song MA, Kwee SA, Tiirikainen M, Hernandez BY, Okimoto G, Tsai NC, Wong LL, Yu H.

Epigenetics. 2016 Jun 2;11(6):464-74. doi: 10.1080/15592294.2016.1151586. Epub 2016 Jun 1.

16.

Metabolic characteristics distinguishing intrahepatic cholangiocarcinoma: a negative pilot study of (18)F-fluorocholine PET/CT clarified by transcriptomic analysis.

Kwee SA, Okimoto GS, Chan OT, Tiirikainen M, Wong LL.

Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):73-83. eCollection 2016.

17.

Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity.

Park SL, Tiirikainen MI, Patel YM, Wilkens LR, Stram DO, Le Marchand L, Murphy SE.

Carcinogenesis. 2016 Mar;37(3):269-279. doi: 10.1093/carcin/bgw012. Epub 2016 Jan 27.

18.

Genome-scale hypomethylation in the cord blood DNAs associated with early onset preeclampsia.

Ching T, Ha J, Song MA, Tiirikainen M, Molnar J, Berry MJ, Towner D, Garmire LX.

Clin Epigenetics. 2015 Mar 13;7:21. doi: 10.1186/s13148-015-0052-x. eCollection 2015.

19.

High Incidence of Somatic BAP1 alterations in sporadic malignant mesothelioma.

Nasu M, Emi M, Pastorino S, Tanji M, Powers A, Luk H, Baumann F, Zhang YA, Gazdar A, Kanodia S, Tiirikainen M, Flores E, Gaudino G, Becich MJ, Pass HI, Yang H, Carbone M.

J Thorac Oncol. 2015 Apr;10(4):565-76. doi: 10.1097/JTO.0000000000000471.

20.

Intraindividual variation and short-term temporal trend in DNA methylation of human blood.

Shvetsov YB, Song MA, Cai Q, Tiirikainen M, Xiang YB, Shu XO, Yu H.

Cancer Epidemiol Biomarkers Prev. 2015 Mar;24(3):490-7. doi: 10.1158/1055-9965.EPI-14-0853. Epub 2014 Dec 23.

21.

1,3-Butadiene exposure and metabolism among Japanese American, Native Hawaiian, and White smokers.

Park SL, Kotapati S, Wilkens LR, Tiirikainen M, Murphy SE, Tretyakova N, Le Marchand L.

Cancer Epidemiol Biomarkers Prev. 2014 Nov;23(11):2240-9. doi: 10.1158/1055-9965.EPI-14-0492.

22.

Genome-wide hypermethylation coupled with promoter hypomethylation in the chorioamniotic membranes of early onset pre-eclampsia.

Ching T, Song MA, Tiirikainen M, Molnar J, Berry M, Towner D, Garmire LX.

Mol Hum Reprod. 2014 Sep;20(9):885-904. doi: 10.1093/molehr/gau046. Epub 2014 Jun 18.

23.

Pleiotropy of cancer susceptibility variants on the risk of non-Hodgkin lymphoma: the PAGE consortium.

Lim U, Kocarnik JM, Bush WS, Matise TC, Caberto C, Park SL, Carlson CS, Deelman E, Duggan D, Fesinmeyer M, Haiman CA, Henderson BE, Hindorff LA, Kolonel LN, Peters U, Stram DO, Tiirikainen M, Wilkens LR, Wu C, Kooperberg C, Le Marchand L.

PLoS One. 2014 Mar 5;9(3):e89791. doi: 10.1371/journal.pone.0089791. eCollection 2014.

24.

Continuous exposure to chrysotile asbestos can cause transformation of human mesothelial cells via HMGB1 and TNF-α signaling.

Qi F, Okimoto G, Jube S, Napolitano A, Pass HI, Laczko R, Demay RM, Khan G, Tiirikainen M, Rinaudo C, Croce A, Yang H, Gaudino G, Carbone M.

Am J Pathol. 2013 Nov;183(5):1654-66. doi: 10.1016/j.ajpath.2013.07.029.

25.

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer.

Ling H, Spizzo R, Atlasi Y, Nicoloso M, Shimizu M, Redis RS, Nishida N, Gafà R, Song J, Guo Z, Ivan C, Barbarotto E, De Vries I, Zhang X, Ferracin M, Churchman M, van Galen JF, Beverloo BH, Shariati M, Haderk F, Estecio MR, Garcia-Manero G, Patijn GA, Gotley DC, Bhardwaj V, Shureiqi I, Sen S, Multani AS, Welsh J, Yamamoto K, Taniguchi I, Song MA, Gallinger S, Casey G, Thibodeau SN, Le Marchand L, Tiirikainen M, Mani SA, Zhang W, Davuluri RV, Mimori K, Mori M, Sieuwerts AM, Martens JW, Tomlinson I, Negrini M, Berindan-Neagoe I, Foekens JA, Hamilton SR, Lanza G, Kopetz S, Fodde R, Calin GA.

Genome Res. 2013 Sep;23(9):1446-61. doi: 10.1101/gr.152942.112. Epub 2013 Jun 24.

26.

Genetic associations of relaxin: preterm birth and premature rupture of fetal membranes.

Rocha FG, Slavin TP, Li D, Tiirikainen MI, Bryant-Greenwood GD.

Am J Obstet Gynecol. 2013 Sep;209(3):258.e1-8. doi: 10.1016/j.ajog.2013.05.020. Epub 2013 May 10.

27.

Elucidating the landscape of aberrant DNA methylation in hepatocellular carcinoma.

Song MA, Tiirikainen M, Kwee S, Okimoto G, Yu H, Wong LL.

PLoS One. 2013;8(2):e55761. doi: 10.1371/journal.pone.0055761. Epub 2013 Feb 20.

28.

Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.

Loo LW, Tiirikainen M, Cheng I, Lum-Jones A, Seifried A, Church JM, Gryfe R, Weisenberger DJ, Lindor NM, Gallinger S, Haile RW, Duggan DJ, Thibodeau SN, Casey G, Le Marchand L.

Genes Chromosomes Cancer. 2013 May;52(5):450-66. doi: 10.1002/gcc.22043. Epub 2013 Jan 23.

29.

Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studies.

Lim U, Wilkens LR, Monroe KR, Caberto C, Tiirikainen M, Cheng I, Park SL, Stram DO, Henderson BE, Kolonel LN, Haiman CA, Le Marchand L.

Int J Cancer. 2012 Sep 15;131(6):E1038-43. doi: 10.1002/ijc.27592. Epub 2012 Apr 30.

30.

Measurement of circulating cell-free DNA in relation to 18F-fluorocholine PET/CT imaging in chemotherapy-treated advanced prostate cancer.

Kwee S, Song MA, Cheng I, Loo L, Tiirikainen M.

Clin Transl Sci. 2012 Feb;5(1):65-70. doi: 10.1111/j.1752-8062.2011.00375.x. Epub 2012 Feb 23.

31.

cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.

Loo LW, Cheng I, Tiirikainen M, Lum-Jones A, Seifried A, Dunklee LM, Church JM, Gryfe R, Weisenberger DJ, Haile RW, Gallinger S, Duggan DJ, Thibodeau SN, Casey G, Le Marchand L.

PLoS One. 2012;7(2):e30477. doi: 10.1371/journal.pone.0030477. Epub 2012 Feb 17.

32.

ZEB1 limits adenoviral infectability by transcriptionally repressing the coxsackie virus and adenovirus receptor.

Lacher MD, Shiina M, Chang P, Keller D, Tiirikainen MI, Korn WM.

Mol Cancer. 2011 Jul 27;10:91. doi: 10.1186/1476-4598-10-91.

33.

Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.

Cheng I, Caberto CP, Lum-Jones A, Seifried A, Wilkens LR, Schumacher FR, Monroe KR, Lim U, Tiirikainen M, Kolonel LN, Henderson BE, Stram DO, Haiman CA, Le Marchand L.

Gut. 2011 Dec;60(12):1703-11. doi: 10.1136/gut.2011.237727. Epub 2011 May 20.

34.

Plasma levels of B vitamins and colorectal cancer risk: the multiethnic cohort study.

Le Marchand L, White KK, Nomura AM, Wilkens LR, Selhub JS, Tiirikainen M, Goodman MT, Murphy SP, Henderson BE, Kolonel LN.

Cancer Epidemiol Biomarkers Prev. 2009 Aug;18(8):2195-201. doi: 10.1158/1055-9965.EPI-09-0141.

35.

Urinary isothiocyanates; glutathione S-transferase M1, T1, and P1 polymorphisms; and risk of colorectal cancer: the Multiethnic Cohort Study.

Epplein M, Wilkens LR, Tiirikainen M, Dyba M, Chung FL, Goodman MT, Murphy SP, Henderson BE, Kolonel LN, Le Marchand L.

Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):314-20. doi: 10.1158/1055-9965.EPI-08-0627.

36.

Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine.

Le Marchand L, Derby KS, Murphy SE, Hecht SS, Hatsukami D, Carmella SG, Tiirikainen M, Wang H.

Cancer Res. 2008 Nov 15;68(22):9137-40. doi: 10.1158/0008-5472.CAN-08-2271.

37.

Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry.

Poynter JN, Figueiredo JC, Conti DV, Kennedy K, Gallinger S, Siegmund KD, Casey G, Thibodeau SN, Jenkins MA, Hopper JL, Byrnes GB, Baron JA, Goode EL, Tiirikainen M, Lindor N, Grove J, Newcomb P, Jass J, Young J, Potter JD, Haile RW, Duggan DJ, Le Marchand L; Colon CFR.

Cancer Res. 2007 Dec 1;67(23):11128-32.

38.
39.

Genomic alterations in human mesothelioma including high resolution mapping of common regions of DNA loss in chromosome arm 6q.

Jensen RH, Tiirikainen M, You L, Ginzinger D, He B, Uematsu K, Xu Z, Treseler P, McCormick F, Jablons DM.

Anticancer Res. 2003 May-Jun;23(3B):2281-9.

PMID:
12894504
40.

Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors.

Zardo G, Tiirikainen MI, Hong C, Misra A, Feuerstein BG, Volik S, Collins CC, Lamborn KR, Bollen A, Pinkel D, Albertson DG, Costello JF.

Nat Genet. 2002 Nov;32(3):453-8. Epub 2002 Sep 30.

PMID:
12355068
41.

DNA copy number alterations in HIV-positive and HIV-negative patients with diffuse large-cell lymphomas.

Tiirikainen MI, Mullaney BP, Holly EA, Pallavicini MG, Jensen RH.

J Acquir Immune Defic Syndr. 2001 Jul 1;27(3):272-6.

PMID:
11464147
42.

Initial P-glycoprotein expression in childhood acute lymphoblastic leukemia: no evidence of prognostic impact in follow-up.

Kanerva J, Tiirikainen MI, Mäkipernaa A, Riikonen P, Möttönen M, Salmi TT, Krusius T, Saarinen-Pihkala UM.

Pediatr Hematol Oncol. 2001 Jan-Feb;18(1):27-36.

PMID:
11205837
43.

Multiple drug resistance mediated by P-glycoprotein is not a major factor in a slow response to therapy in childhood ALL.

Kanerva J, Tiirikainen M, Mäkipernaa A, Riikonen P, Möttönen M, Salmi TT, Krusius T, Saarinen-Pihkala UM.

Pediatr Hematol Oncol. 1998 Jan-Feb;15(1):11-21.

PMID:
9509502
44.

Protoporphyrin-IX distribution and photodynamic effect in rat oesophagus after aminolaevulinic acid administration.

Mäkinen K, Grönlund-Pakkanen S, Tiirikainen M, Nuutinen P, Kuusisto A, Alhava E.

Scand J Gastroenterol. 1997 Jul;32(7):633-7.

PMID:
9246700
46.

Flow cytometric analysis of glutathione-S-transferase-pi in acute leukemia.

Tiirikainen MI, Elonen E, Syrjälä MT, Jansson SE, Krusius T.

Leukemia. 1994 Jun;8(6):978-84.

PMID:
7516031
47.

Clinical significance of P-glycoprotein expression in acute leukaemia as analysed by immunocytochemistry.

Tiirikainen MI, Elonen E, Ruutu T, Jansson SE, Krusius T.

Eur J Haematol. 1993 May;50(5):279-85.

PMID:
8100537
48.

Flow cytometric analysis of terminal deoxynucleotidyl transferase. A simplified method.

Syrjälä MT, Tiirikainen M, Jansson SE, Krusius T.

Am J Clin Pathol. 1993 Mar;99(3):298-303.

PMID:
8447292
49.

Flow cytometric analysis of P-glycoprotein in normal and leukemic cells.

Tiirikainen MI, Syrjälä MT, Jansson SE, Krusius T.

Ann Hematol. 1992 Sep;65(3):124-30.

PMID:
1356449
50.

Multidrug resistance.

Tiirikainen MI, Krusius T.

Ann Med. 1991;23(5):509-20. Review.

PMID:
1684512

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