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Items: 1 to 50 of 51

1.

Exercise capacity reflects airflow limitation rather than hypoxaemia in patients with pulmonary arteriovenous malformations.

Gawecki F, Strangeways T, Amin A, Perks J, McKernan H, Thurainatnam S, Rizvi A, Jackson JE, Santhirapala V, Myers J, Brown J, Howard LSGE, Tighe HC, Shovlin CL.

QJM. 2019 May 1;112(5):335-342. doi: 10.1093/qjmed/hcz023.

PMID:
30657990
2.

Cerebral Abscess Associated With Odontogenic Bacteremias, Hypoxemia, and Iron Loading in Immunocompetent Patients With Right-to-Left Shunting Through Pulmonary Arteriovenous Malformations.

Boother EJ, Brownlow S, Tighe HC, Bamford KB, Jackson JE, Shovlin CL.

Clin Infect Dis. 2017 Aug 15;65(4):595-603. doi: 10.1093/cid/cix373.

3.

Hemoglobin Is a Vital Determinant of Arterial Oxygen Content in Hypoxemic Patients with Pulmonary Arteriovenous Malformations.

Rizvi A, Macedo P, Babawale L, Tighe HC, Hughes JMB, Jackson JE, Shovlin CL.

Ann Am Thorac Soc. 2017 Jun;14(6):903-911. doi: 10.1513/AnnalsATS.201611-872OC.

4.

Orthodeoxia and postural orthostatic tachycardia in patients with pulmonary arteriovenous malformations: a prospective 8-year series.

Santhirapala V, Chamali B, McKernan H, Tighe HC, Williams LC, Springett JT, Bellenberg HR, Whitaker AJ, Shovlin CL.

Thorax. 2014 Nov;69(11):1046-7. doi: 10.1136/thoraxjnl-2014-205289. Epub 2014 Apr 8.

PMID:
24713588
5.

Cardiopulmonary exercise testing demonstrates maintenance of exercise capacity in patients with hypoxemia and pulmonary arteriovenous malformations.

Howard LSGE, Santhirapala V, Murphy K, Mukherjee B, Busbridge M, Tighe HC, Jackson JE, Hughes JMB, Shovlin CL.

Chest. 2014 Sep;146(3):709-718. doi: 10.1378/chest.13-2988.

7.

Ischaemic strokes in patients with pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia: associations with iron deficiency and platelets.

Shovlin CL, Chamali B, Santhirapala V, Livesey JA, Angus G, Manning R, Laffan MA, Meek J, Tighe HC, Jackson JE.

PLoS One. 2014 Feb 19;9(2):e88812. doi: 10.1371/journal.pone.0088812. eCollection 2014.

8.

Differences in ventilatory inefficiency between pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Zhai Z, Murphy K, Tighe H, Wang C, Wilkins MR, Gibbs JSR, Howard LS.

Chest. 2011 Nov;140(5):1284-1291. doi: 10.1378/chest.10-3357. Epub 2011 Apr 28.

PMID:
21527511
9.

Group B streptococcal disease in infants: a case control study.

Heath PT, Balfour GF, Tighe H, Verlander NQ, Lamagni TL, Efstratiou A; HPA GBS Working Group.

Arch Dis Child. 2009 Sep;94(9):674-80. doi: 10.1136/adc.2008.148874. Epub 2009 May 19.

PMID:
19457879
10.

Is necrotizing enterocolitis associated with development or progression of intraventricular hemorrhage?

Hall NJ, Hiorns M, Tighe H, Peters M, Khoo AK, Eaton S, Pierro A.

Am J Perinatol. 2009 Feb;26(2):139-43. doi: 10.1055/s-0028-1095177. Epub 2008 Oct 31. Review.

PMID:
18979411
11.

Embolisation of pulmonary arteriovenous malformations: no consistent effect on pulmonary artery pressure.

Shovlin CL, Tighe HC, Davies RJ, Gibbs JS, Jackson JE.

Eur Respir J. 2008 Jul;32(1):162-9. doi: 10.1183/09031936.00126207. Epub 2008 Apr 2.

12.

Immunogenicity and immunologic memory of meningococcal C conjugate vaccine in premature infants.

Collins CL, Ruggeberg JU, Balfour G, Tighe H, Archer M, Bowen-Morris J, Diggle L, Borrow R, Balmer P, Buttery JP, Moxon ER, Pollard AJ, Heath PT.

Pediatr Infect Dis J. 2005 Nov;24(11):966-8.

PMID:
16282930
14.

Group B streptococcal disease in UK and Irish infants younger than 90 days.

Heath PT, Balfour G, Weisner AM, Efstratiou A, Lamagni TL, Tighe H, O'Connell LA, Cafferkey M, Verlander NQ, Nicoll A, McCartney AC; PHLS Group B Streptococcus Working Group.

Lancet. 2004 Jan 24;363(9405):292-4.

PMID:
14751704
15.

Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity.

Tighe H, Takabayashi K, Schwartz D, Marsden R, Beck L, Corbeil J, Richman DD, Eiden JJ Jr, Spiegelberg HL, Raz E.

Eur J Immunol. 2000 Jul;30(7):1939-47.

16.

Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity.

Tighe H, Takabayashi K, Schwartz D, Van Nest G, Tuck S, Eiden JJ, Kagey-Sobotka A, Creticos PS, Lichtenstein LM, Spiegelberg HL, Raz E.

J Allergy Clin Immunol. 2000 Jul;106(1 Pt 1):124-34.

PMID:
10887315
17.

Genetic immunization for allergy immunotherapy.

Roman M, Tighe H, Spiegelberg HL, Broide D, Raz E.

Methods Mol Med. 2000;29:451-72. doi: 10.1385/1-59259-688-6:451.

PMID:
21374341
18.

In vivo priming by DNA injection occurs predominantly by antigen transfer.

Corr M, von Damm A, Lee DJ, Tighe H.

J Immunol. 1999 Nov 1;163(9):4721-7.

19.

Human rheumatoid factor production is dependent on CD40 signaling and autoantigen.

Kyburz D, Corr M, Brinson DC, Von Damm A, Tighe H, Carson DA.

J Immunol. 1999 Sep 15;163(6):3116-22.

20.

Inhibition of allergic inflammation in the lung by plasmid DNA allergen immunization.

Spiegelberg HL, Broide D, Tighe H, Roman M, Raz E.

Pediatr Pulmonol Suppl. 1999;18:118-21.

PMID:
10093118
21.

Rheumatoid factor B cell tolerance via autonomous Fas/FasL-independent apoptosis.

Warnatz K, Kyburz D, Brinson DC, Lee DJ, Von Damm A, Engelhart M, Corr M, Carson DA, Tighe H.

Cell Immunol. 1999 Jan 10;191(1):69-73.

PMID:
9918688
22.

Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice.

Broide D, Schwarze J, Tighe H, Gifford T, Nguyen MD, Malek S, Van Uden J, Martin-Orozco E, Gelfand EW, Raz E.

J Immunol. 1998 Dec 15;161(12):7054-62.

23.

The dual phases of the response to neonatal exposure to a VH family-restricted staphylococcal B cell superantigen.

Silverman GJ, Nayak JV, Warnatz K, Hajjar FF, Cary S, Tighe H, Curtiss VE.

J Immunol. 1998 Nov 15;161(10):5720-32.

24.

Inhibition of IgE formation and allergic inflammation by allergen gene immunization and by CpG motif immunostimulatory oligodeoxynucleotides.

Spiegelberg HL, Tighe H, Roman M, Broide D, Raz E.

Allergy. 1998;53(45 Suppl):93-7. No abstract available.

PMID:
9788716
25.

Gene vaccination: plasmid DNA is more than just a blueprint.

Tighe H, Corr M, Roman M, Raz E.

Immunol Today. 1998 Feb;19(2):89-97. Review. No abstract available.

PMID:
9509764
26.

Costimulation provided by DNA immunization enhances antitumor immunity.

Corr M, Tighe H, Lee D, Dudler J, Trieu M, Brinson DC, Carson DA.

J Immunol. 1997 Nov 15;159(10):4999-5004.

PMID:
9366427
27.

Inhibition of IgE antibody formation by plasmid DNA immunization is mediated by both CD4+ and CD8+ T cells.

Lee DJ, Tighe H, Corr M, Roman M, Carson DA, Spiegelberg HL, Raz E.

Int Arch Allergy Immunol. 1997 May-Jul;113(1-3):227-30.

PMID:
9130530
28.

Peripheral deletion of rheumatoid factor B cells after abortive activation by IgG.

Tighe H, Warnatz K, Brinson D, Corr M, Weigle WO, Baird SM, Carson DA.

Proc Natl Acad Sci U S A. 1997 Jan 21;94(2):646-51.

29.

Plasmid DNA vaccination: mechanism of antigen presentation.

Corr M, Tighe H.

Springer Semin Immunopathol. 1997;19(2):139-45. Review. No abstract available.

PMID:
9406342
30.

Gene vaccination with naked plasmid DNA: mechanism of CTL priming.

Corr M, Lee DJ, Carson DA, Tighe H.

J Exp Med. 1996 Oct 1;184(4):1555-60.

31.

Immunostimulatory DNA sequences necessary for effective intradermal gene immunization.

Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, Silverman GJ, Lotz M, Carson DA, Raz E.

Science. 1996 Jul 19;273(5273):352-4.

PMID:
8662521
32.

Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.

Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman M, Swain SL, Spiegelberg HL, Carson DA.

Proc Natl Acad Sci U S A. 1996 May 14;93(10):5141-5.

33.

Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice.

Tighe H, Heaphy P, Baird S, Weigle WO, Carson DA.

J Exp Med. 1995 Feb 1;181(2):599-606.

34.

Induction of antibodies to a kappa V region by gene immunization.

Watanabe A, Raz E, Kohsaka H, Tighe H, Baird SM, Kipps TJ, Carson DA.

J Immunol. 1993 Sep 1;151(5):2871-6.

PMID:
8360497
35.

Function of B cells expressing a human immunoglobulin M rheumatoid factor autoantibody in transgenic mice.

Tighe H, Chen PP, Tucker R, Kipps TJ, Roudier J, Jirik FR, Carson DA.

J Exp Med. 1993 Jan 1;177(1):109-18.

36.

Generation and characterization of two monoclonal self-associating IgG rheumatoid factors from a rheumatoid synovium.

Lu EW, Deftos M, Tighe H, Carson DA, Chen PP.

Arthritis Rheum. 1992 Jan;35(1):101-5.

PMID:
1731807
37.

The anti-IL-2 receptor monoclonal antibody YTH-906 in liver transplantation.

Friend PJ, Waldmann H, Cobbold S, Tighe H, Rebello P, Wight D, Gore S, Pollard S, Lim S, Johnston P, et al.

Transplant Proc. 1991 Feb;23(1 Pt 2):1390-2. No abstract available.

PMID:
1989247
38.

Autoantibody production by severe combined immunodeficient mice reconstituted with synovial cells from rheumatoid arthritis patients.

Tighe H, Silverman GJ, Kozin F, Tucker R, Gulizia R, Peebles C, Lotz M, Rhodes G, Machold K, Mosier DE, et al.

Eur J Immunol. 1990 Aug;20(8):1843-8.

PMID:
2209691
39.

Probing of the rheumatoid factor (RF) V gene repertoire in rheumatoid arthritis (RA) by hybridoma clones.

Natvig JB, Randen I, Thompson K, Førre O, Mageed RA, Jefferis R, Carson DA, Tighe H, Pascual V, Victor KD, et al.

Clin Exp Rheumatol. 1990 Jul-Aug;8 Suppl 5:75-80.

PMID:
2123137
40.

Human monoclonal rheumatoid factors derived from the polyclonal repertoire of rheumatoid synovial tissue: incidence of cross-reactive idiotopes and expression of VH and V kappa subgroups.

Thompson KM, Randen I, Natvig JB, Mageed RA, Jefferis R, Carson DA, Tighe H, Forre O.

Eur J Immunol. 1990 Apr;20(4):863-8.

PMID:
1693338
41.

The CAMPATH-1 antigen (CDw52).

Hale G, Xia MQ, Tighe HP, Dyer MJ, Waldmann H.

Tissue Antigens. 1990 Mar;35(3):118-27. No abstract available.

PMID:
2165283
42.

Regulation of rheumatoid factor synthesis.

Carson DA, Chen PP, Kipps TJ, Roudier J, Silverman GJ, Tighe H.

Clin Exp Rheumatol. 1989 Sep-Oct;7 Suppl 3:S69-73. Review.

PMID:
2691162
43.

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.

Davies A, Simmons DL, Hale G, Harrison RA, Tighe H, Lachmann PJ, Waldmann H.

J Exp Med. 1989 Sep 1;170(3):637-54.

44.

Beneficial effect of monoclonal antibody to interleukin 2 receptor on activated T cells in rheumatoid arthritis.

Kyle V, Coughlan RJ, Tighe H, Waldmann H, Hazleman BL.

Ann Rheum Dis. 1989 May;48(5):428-9.

45.

Delayed allograft rejection in primates treated with anti-IL-2 receptor monoclonal antibody Campath-6.

Tighe H, Friend PJ, Collier SJ, Decurtins M, Lim S, Cobbold SP, Thiru S, Calne RY, Waldmann H.

Transplantation. 1988 Jan;45(1):226-8. No abstract available.

PMID:
3122385
46.
47.

The use of monoclonal antibodies against activated human T cells following renal allografting in the baboon.

Friend PJ, Tighe H, Lim S, Collier DS, Decurtins M, Gilliland LK, Thiru S, Calne R, Waldmann H.

Transplant Proc. 1987 Oct;19(5):4317-8. No abstract available.

PMID:
3314035
48.

CD4 monoclonal antibody pairs for immunosuppression and tolerance induction.

Qin S, Cobbold S, Tighe H, Benjamin R, Waldmann H.

Eur J Immunol. 1987 Aug;17(8):1159-65.

PMID:
2441998
49.

Rat monoclonal antibodies for bone marrow transplantation--the CAMPATH series.

Waldmann H, Cobbold S, Wilson A, Clark M, Watt S, Hale G, Tighe H.

Adv Exp Med Biol. 1985;186:869-75. No abstract available.

PMID:
3901694
50.

T-cell control of Epstein-Barr virus-infected B cells is lost during P. falciparum malaria.

Whittle HC, Brown J, Marsh K, Greenwood BM, Seidelin P, Tighe H, Wedderburn L.

Nature. 1984 Nov 29-Dec 5;312(5993):449-50.

PMID:
6095104

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