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Items: 19

1.

Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression.

Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, Pober JS.

JCI Insight. 2019 Oct 17;4(20). pii: 129739. doi: 10.1172/jci.insight.129739.

2.

Tailoring Biomimetic Phosphorylcholine-Containing Block Copolymers as Membrane-Targeting Cellular Rescue Agents.

Wang JY, Chen W, Nagao M, Shelat P, Hammer BAG, Tietjen GT, Cao KD, Henderson JM, He L, Lin B, Akgun B, Meron M, Qian S, Ward S, Marks JD, Emrick T, Lee KYC.

Biomacromolecules. 2019 Sep 9;20(9):3385-3391. doi: 10.1021/acs.biomac.9b00621. Epub 2019 Aug 19.

PMID:
31424203
3.

ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.

Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D.

Nat Commun. 2019 May 21;10(1):2247. doi: 10.1038/s41467-019-10041-2.

4.

Poly(amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver.

Cui J, Piotrowski-Daspit AS, Zhang J, Shao M, Bracaglia LG, Utsumi T, Seo YE, DiRito J, Song E, Wu C, Inada A, Tietjen GT, Pober JS, Iwakiri Y, Saltzman WM.

J Control Release. 2019 Jun 28;304:259-267. doi: 10.1016/j.jconrel.2019.04.044. Epub 2019 May 1.

PMID:
31054286
5.

Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins.

Kerr D, Tietjen GT, Gong Z, Tajkhorshid E, Adams EJ, Lee KYC.

Biochim Biophys Acta Biomembr. 2018 Oct;1860(10):2126-2133. doi: 10.1016/j.bbamem.2018.06.010. Epub 2018 Jun 18. Review.

6.

Focus on Fundamentals: Achieving Effective Nanoparticle Targeting.

Tietjen GT, Bracaglia LG, Saltzman WM, Pober JS.

Trends Mol Med. 2018 Jul;24(7):598-606. doi: 10.1016/j.molmed.2018.05.003. Epub 2018 Jun 5. Review.

7.

A "top-down" approach to actuate poly(amine-co-ester) terpolymers for potent and safe mRNA delivery.

Jiang Y, Gaudin A, Zhang J, Agarwal T, Song E, Kauffman AC, Tietjen GT, Wang Y, Jiang Z, Cheng CJ, Saltzman WM.

Biomaterials. 2018 Sep;176:122-130. doi: 10.1016/j.biomaterials.2018.05.043. Epub 2018 May 25.

8.

The future of marginal kidney repair in the context of normothermic machine perfusion.

DiRito JR, Hosgood SA, Tietjen GT, Nicholson ML.

Am J Transplant. 2018 Oct;18(10):2400-2408. doi: 10.1111/ajt.14963. Epub 2018 Jul 2. Review.

9.

Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1.

Liu R, Merola J, Manes TD, Qin L, Tietjen GT, López-Giráldez F, Broecker V, Fang C, Xie C, Chen PM, Kirkiles-Smith NC, Jane-Wit D, Pober JS.

JCI Insight. 2018 Mar 8;3(5). pii: 97881. doi: 10.1172/jci.insight.97881.

10.

Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys.

Tietjen GT, Hosgood SA, DiRito J, Cui J, Deep D, Song E, Kraehling JR, Piotrowski-Daspit AS, Kirkiles-Smith NC, Al-Lamki R, Thiru S, Bradley JA, Saeb-Parsy K, Bradley JR, Nicholson ML, Saltzman WM, Pober JS.

Sci Transl Med. 2017 Nov 29;9(418). pii: eaam6764. doi: 10.1126/scitranslmed.aam6764.

11.

Coupling X-Ray Reflectivity and In Silico Binding to Yield Dynamics of Membrane Recognition by Tim1.

Tietjen GT, Baylon JL, Kerr D, Gong Z, Henderson JM, Heffern CTR, Meron M, Lin B, Schlossman ML, Adams EJ, Tajkhorshid E, Lee KYC.

Biophys J. 2017 Oct 3;113(7):1505-1519. doi: 10.1016/j.bpj.2017.08.003.

12.

Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells.

Cui J, Qin L, Zhang J, Abrahimi P, Li H, Li G, Tietjen GT, Tellides G, Pober JS, Mark Saltzman W.

Nat Commun. 2017 Aug 4;8(1):191. doi: 10.1038/s41467-017-00297-x.

13.

Surface chemistry governs cellular tropism of nanoparticles in the brain.

Song E, Gaudin A, King AR, Seo YE, Suh HW, Deng Y, Cui J, Tietjen GT, Huttner A, Saltzman WM.

Nat Commun. 2017 May 19;8:15322. doi: 10.1038/ncomms15322.

14.

Quantitative microscopy-based measurements of circulating nanoparticle concentration using microliter blood volumes.

Tietjen GT, DiRito J, Pober JS, Saltzman WM.

Nanomedicine. 2017 Aug;13(6):1863-1867. doi: 10.1016/j.nano.2017.04.003. Epub 2017 Apr 13.

PMID:
28412144
15.

Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence.

Gavrilov K, Seo YE, Tietjen GT, Cui J, Cheng CJ, Saltzman WM.

Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):E6597-605. doi: 10.1073/pnas.1517039112. Epub 2015 Nov 16.

16.

Nanomedicine gets personal.

Tietjen GT, Saltzman WM.

Sci Transl Med. 2015 Nov 18;7(314):314fs47. doi: 10.1126/scitranslmed.aad6645.

PMID:
26582895
17.

A holistic approach to targeting disease with polymeric nanoparticles.

Cheng CJ, Tietjen GT, Saucier-Sawyer JK, Saltzman WM.

Nat Rev Drug Discov. 2015 Apr;14(4):239-47. doi: 10.1038/nrd4503. Epub 2015 Jan 19. Review.

18.

Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4.

Tietjen GT, Gong Z, Chen CH, Vargas E, Crooks JE, Cao KD, Heffern CT, Henderson JM, Meron M, Lin B, Roux B, Schlossman ML, Steck TL, Lee KY, Adams EJ.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1463-72. doi: 10.1073/pnas.1320174111. Epub 2014 Mar 31.

19.

An efficient method for the creation of tunable optical line traps via control of gradient and scattering forces.

Tietjen GT, Kong Y, Parthasarathy R.

Opt Express. 2008 Jul 7;16(14):10341-8.

PMID:
18607444

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