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Items: 14


Keys to unlock androgen receptor translocation.

Tien AH, Sadar MD.

J Biol Chem. 2019 May 31;294(22):8711-8712. doi: 10.1074/jbc.H119.009180.


Order within a Disordered Structure.

Tien AH, Sadar MD.

Structure. 2018 Jan 2;26(1):4-6. doi: 10.1016/j.str.2017.12.007.


Sintokamide A Is a Novel Antagonist of Androgen Receptor That Uniquely Binds Activation Function-1 in Its Amino-terminal Domain.

Banuelos CA, Tavakoli I, Tien AH, Caley DP, Mawji NR, Li Z, Wang J, Yang YC, Imamura Y, Yan L, Wen JG, Andersen RJ, Sadar MD.

J Biol Chem. 2016 Oct 14;291(42):22231-22243. Epub 2016 Aug 30.


An imaging agent to detect androgen receptor and its active splice variants in prostate cancer.

Imamura Y, Tien AH, Pan J, Leung JK, Banuelos CA, Jian K, Wang J, Mawji NR, Fernandez JG, Lin KS, Andersen RJ, Sadar MD.

JCI Insight. 2016 Jul 21;1(11). pii: e87850.


Differentiation of retinal ganglion cells and photoreceptor precursors from mouse induced pluripotent stem cells carrying an Atoh7/Math5 lineage reporter.

Xie BB, Zhang XM, Hashimoto T, Tien AH, Chen A, Ge J, Yang XJ.

PLoS One. 2014 Nov 17;9(11):e112175. doi: 10.1371/journal.pone.0112175. eCollection 2014.


Characterization of niphatenones that inhibit androgen receptor N-terminal domain.

Banuelos CA, Lal A, Tien AH, Shah N, Yang YC, Mawji NR, Meimetis LG, Park J, Kunzhong J, Andersen RJ, Sadar MD.

PLoS One. 2014 Sep 30;9(9):e107991. doi: 10.1371/journal.pone.0107991. eCollection 2014.


An androgen receptor N-terminal domain antagonist for treating prostate cancer.

Myung JK, Banuelos CA, Fernandez JG, Mawji NR, Wang J, Tien AH, Yang YC, Tavakoli I, Haile S, Watt K, McEwan IJ, Plymate S, Andersen RJ, Sadar MD.

J Clin Invest. 2013 Jul;123(7):2948-60. doi: 10.1172/JCI66398. Epub 2013 Jun 3.


Spongian diterpenoids inhibit androgen receptor activity.

Yang YC, Meimetis LG, Tien AH, Mawji NR, Carr G, Wang J, Andersen RJ, Sadar MD.

Mol Cancer Ther. 2013 May;12(5):621-31. doi: 10.1158/1535-7163.MCT-12-0978. Epub 2013 Feb 26.


Niphatenones, glycerol ethers from the sponge Niphates digitalis block androgen receptor transcriptional activity in prostate cancer cells: structure elucidation, synthesis, and biological activity.

Meimetis LG, Williams DE, Mawji NR, Banuelos CA, Lal AA, Park JJ, Tien AH, Fernandez JG, de Voogd NJ, Sadar MD, Andersen RJ.

J Med Chem. 2012 Jan 12;55(1):503-14. doi: 10.1021/jm2014056. Epub 2011 Dec 28.


Osteoblast-derived factors induce an expression signature that identifies prostate cancer metastasis and hormonal progression.

Wang G, Haile S, Comuzzi B, Tien AH, Wang J, Yong TM, Jelescu-Bodos AE, Blaszczyk N, Vessella RL, Masri BA, Sadar MD.

Cancer Res. 2009 Apr 15;69(8):3433-42. doi: 10.1158/0008-5472.CAN-08-3506. Epub 2009 Apr 7.


Involvement of tyrosine kinase signaling in maintaining murine embryonic stem cell functionality.

Lu M, Glover CH, Tien AH, Humphries RK, Piret JM, Helgason CD.

Exp Hematol. 2007 Aug;35(8):1293-302. Epub 2007 Jun 11.


SHIP-deficient mice provide insights into the regulation of dendritic cell development and function.

Neill L, Tien AH, Rey-Ladino J, Helgason CD.

Exp Hematol. 2007 Apr;35(4):627-39.


Identification of novel genes and transcription factors involved in spleen, thymus and immunological development and function.

Hoffman BG, Williams KL, Tien AH, Lu V, de Algara TR, Ting JP, Helgason CD.

Genes Immun. 2006 Mar;7(2):101-12.


Altered immunity accompanies disease progression in a mouse model of prostate dysplasia.

Tien AH, Xu L, Helgason CD.

Cancer Res. 2005 Apr 1;65(7):2947-55.

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