Sort by
Items per page

Send to

Choose Destination

Search results

Items: 28


Affimers as anti-idiotypic affinity reagents for pharmacokinetic analysis of biotherapeutics.

Adamson H, Nicholl A, Tiede C, Tang AA, Davidson A, Curd H, Wignall A, Ford R, Nuttall J, McPherson MJ, Johnson M, Tomlinson DC.

Biotechniques. 2019 Dec;67(6):261-269. doi: 10.2144/btn-2019-0089. Epub 2019 Sep 5.


Affimer-Enzyme-Inhibitor Switch Sensor for Rapid Wash-free Assays of Multimeric Proteins.

Adamson H, Ajayi MO, Campbell E, Brachi E, Tiede C, Tang AA, Adams TL, Ford R, Davidson A, Johnson M, McPherson MJ, Tomlinson DC, Jeuken LJC.

ACS Sens. 2019 Nov 22;4(11):3014-3022. doi: 10.1021/acssensors.9b01574. Epub 2019 Oct 17.


Affimer reagents as tools in diagnosing plant virus diseases.

Hesketh EL, Tiede C, Adamson H, Adams TL, Byrne MJ, Meshcheriakova Y, Kruse I, McPherson MJ, Lomonossoff GP, Tomlinson DC, Ranson NA.

Sci Rep. 2019 May 17;9(1):7524. doi: 10.1038/s41598-019-43945-6.


Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications.

Kearney KJ, Pechlivani N, King R, Tiede C, Phoenix F, Cheah R, Macrae FL, Simmons KJ, Manfield IW, Smith KA, Spurgeon BEJ, Naseem KM, Ariens RAS, McPherson MJ, Tomlinson DC, Ajjan RA.

Blood. 2019 Mar 14;133(11):1233-1244. doi: 10.1182/blood-2018-06-856195. Epub 2018 Dec 13.


Epidemiology and risk factors of peri-implantitis: A systematic review.

Dreyer H, Grischke J, Tiede C, Eberhard J, Schweitzer A, Toikkanen SE, Glöckner S, Krause G, Stiesch M.

J Periodontal Res. 2018 Oct;53(5):657-681. doi: 10.1111/jre.12562. Epub 2018 Jun 7.


Site-Specific Labeling of Affimers for DNA-PAINT Microscopy.

Schlichthaerle T, Eklund AS, Schueder F, Strauss MT, Tiede C, Curd A, Ries J, Peckham M, Tomlinson DC, Jungmann R.

Angew Chem Int Ed Engl. 2018 Aug 20;57(34):11060-11063. doi: 10.1002/anie.201804020. Epub 2018 Jul 15.


Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells.

Lopata A, Hughes R, Tiede C, Heissler SM, Sellers JR, Knight PJ, Tomlinson D, Peckham M.

Sci Rep. 2018 Apr 26;8(1):6572. doi: 10.1038/s41598-018-24953-4.


Sensitive and selective Affimer-functionalised interdigitated electrode-based capacitive biosensor for Her4 protein tumour biomarker detection.

Zhurauski P, Arya SK, Jolly P, Tiede C, Tomlinson DC, Ko Ferrigno P, Estrela P.

Biosens Bioelectron. 2018 Jun 15;108:1-8. doi: 10.1016/j.bios.2018.02.041. Epub 2018 Feb 21.


Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action.

Robinson JI, Baxter EW, Owen RL, Thomsen M, Tomlinson DC, Waterhouse MP, Win SJ, Nettleship JE, Tiede C, Foster RJ, Owens RJ, Fishwick CWG, Harris SA, Goldman A, McPherson MJ, Morgan AW.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E72-E81. doi: 10.1073/pnas.1707856115. Epub 2017 Dec 15.


Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology.

Hughes DJ, Tiede C, Penswick N, Tang AA, Trinh CH, Mandal U, Zajac KZ, Gaule T, Howell G, Edwards TA, Duan J, Feyfant E, McPherson MJ, Tomlinson DC, Whitehouse A.

Sci Signal. 2017 Nov 14;10(505). pii: eaaj2005. doi: 10.1126/scisignal.aaj2005.


Isolation of isoform-specific binding proteins (Affimers) by phage display using negative selection.

Tang AA, Tiede C, Hughes DJ, McPherson MJ, Tomlinson DC.

Sci Signal. 2017 Nov 14;10(505). pii: eaan0868. doi: 10.1126/scisignal.aan0868.


Development of an Affimer-antibody combined immunological diagnosis kit for glypican-3.

Xie C, Tiede C, Zhang X, Wang C, Li Z, Xu X, McPherson MJ, Tomlinson DC, Xu W.

Sci Rep. 2017 Aug 29;7(1):9608. doi: 10.1038/s41598-017-10083-w.


Alternative reagents to antibodies in imaging applications.

Bedford R, Tiede C, Hughes R, Curd A, McPherson MJ, Peckham M, Tomlinson DC.

Biophys Rev. 2017 Aug;9(4):299-308. doi: 10.1007/s12551-017-0278-2. Epub 2017 Jul 27. Review.


Affimer proteins are versatile and renewable affinity reagents.

Tiede C, Bedford R, Heseltine SJ, Smith G, Wijetunga I, Ross R, AlQallaf D, Roberts AP, Balls A, Curd A, Hughes RE, Martin H, Needham SR, Zanetti-Domingues LC, Sadigh Y, Peacock TP, Tang AA, Gibson N, Kyle H, Platt GW, Ingram N, Taylor T, Coletta LP, Manfield I, Knowles M, Bell S, Esteves F, Maqbool A, Prasad RK, Drinkhill M, Bon RS, Patel V, Goodchild SA, Martin-Fernandez M, Owens RJ, Nettleship JE, Webb ME, Harrison M, Lippiat JD, Ponnambalam S, Peckham M, Smith A, Ferrigno PK, Johnson M, McPherson MJ, Tomlinson DC.

Elife. 2017 Jun 27;6. pii: e24903. doi: 10.7554/eLife.24903.


Ultraefficient Cap-Exchange Protocol To Compact Biofunctional Quantum Dots for Sensitive Ratiometric Biosensing and Cell Imaging.

Wang W, Guo Y, Tiede C, Chen S, Kopytynski M, Kong Y, Kulak A, Tomlinson D, Chen R, McPherson M, Zhou D.

ACS Appl Mater Interfaces. 2017 May 10;9(18):15232-15244. doi: 10.1021/acsami.6b13807. Epub 2017 Apr 27.


Antibody Mimetics for the Detection of Small Organic Compounds Using a Quartz Crystal Microbalance.

Koutsoumpeli E, Tiede C, Murray J, Tang A, Bon RS, Tomlinson DC, Johnson S.

Anal Chem. 2017 Mar 7;89(5):3051-3058. doi: 10.1021/acs.analchem.6b04790. Epub 2017 Feb 15.


Trivalent Gd-DOTA reagents for modification of proteins.

Fisher MJ, Williamson DJ, Burslem GM, Plante JP, Manfield IW, Tiede C, Ault JR, Stockley PG, Plein S, Maqbool A, Tomlinson DC, Foster R, Warriner SL, Bon RS.

RSC Adv. 2015 Dec 9;5(116):96194-96200. Epub 2015 Nov 11.


Inhibition of complement C3 and fibrinogen interaction: a potential novel therapeutic target to reduce cardiovascular disease in diabetes.

King R, Tiede C, Simmons K, Fishwick C, Tomlinson D, Ajjan R.

Lancet. 2015 Feb 26;385 Suppl 1:S57. doi: 10.1016/S0140-6736(15)60372-5.


Post-transplant lymphoproliferative disorders with naso- and oropharyngeal manifestation.

Akbas A, Tiede C, Lemound J, Maecker-Kolhoff B, Kreipe H, Hussein K.

Transpl Int. 2015 Nov;28(11):1299-307. doi: 10.1111/tri.12632. Epub 2015 Jul 30.


Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies.

Kyle HF, Wickson KF, Stott J, Burslem GM, Breeze AL, Tiede C, Tomlinson DC, Warriner SL, Nelson A, Wilson AJ, Edwards TA.

Mol Biosyst. 2015 Oct;11(10):2738-49. doi: 10.1039/c5mb00284b.


Antibody mimetic receptor proteins for label-free biosensors.

Raina M, Sharma R, Deacon SE, Tiede C, Tomlinson D, Davies AG, McPherson MJ, Wälti C.

Analyst. 2015 Feb 7;140(3):803-10. doi: 10.1039/c4an01418a.


Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications.

Tiede C, Tang AA, Deacon SE, Mandal U, Nettleship JE, Owen RL, George SE, Harrison DJ, Owens RJ, Tomlinson DC, McPherson MJ.

Protein Eng Des Sel. 2014 May;27(5):145-55. doi: 10.1093/protein/gzu007. Epub 2014 Mar 25.


Posttransplant lymphoproliferative disorder in pediatric patients.

Hussein K, Tiede C, Maecker-Kolhoff B, Kreipe H.

Pathobiology. 2013;80(6):289-96. doi: 10.1159/000350331. Epub 2013 Aug 30.


Expression of caspase 14 and filaggrin in oral squamous carcinoma.

Scharenberg C, Eckardt A, Tiede C, Kreipe H, Hussein K.

Head Neck Pathol. 2013 Dec;7(4):327-33. doi: 10.1007/s12105-013-0445-0. Epub 2013 May 4.


Risk factors and prognosis in T-cell posttransplantation lymphoproliferative diseases: reevaluation of 163 cases.

Tiede C, Maecker-Kolhoff B, Klein C, Kreipe H, Hussein K.

Transplantation. 2013 Feb 15;95(3):479-88. doi: 10.1097/TP.0b013e3182762e07. Review.


Molecular and clinicopathological analysis of Epstein-Barr virus-associated posttransplant smooth muscle tumors.

Jonigk D, Laenger F, Maegel L, Izykowski N, Rische J, Tiede C, Klein C, Maecker-Kolhoff B, Kreipe H, Hussein K.

Am J Transplant. 2012 Jul;12(7):1908-17. doi: 10.1111/j.1600-6143.2012.04011.x. Epub 2012 Mar 15.


Structure-function studies of an engineered scaffold protein derived from Stefin A. II: Development and applications of the SQT variant.

Stadler LK, Hoffmann T, Tomlinson DC, Song Q, Lee T, Busby M, Nyathi Y, Gendra E, Tiede C, Flanagan K, Cockell SJ, Wipat A, Harwood C, Wagner SD, Knowles MA, Davis JJ, Keegan N, Ferrigno PK.

Protein Eng Des Sel. 2011 Sep;24(9):751-63. doi: 10.1093/protein/gzr019. Epub 2011 May 25.


Engineering a circularly permuted GFP scaffold for peptide presentation.

Paschke M, Tiede C, Höhne W.

J Mol Recognit. 2007 Sep-Oct;20(5):367-78.


Supplemental Content

Support Center