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Items: 28

1.

Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién.

Tayler NM, Boya CA, Herrera L, Moy J, Ng M, Pineda L, Almanza A, Rosero S, Coronado LM, Correa R, Santamaría R, Caballero Z, Durant-Archibold AA, Tidgewell KJ, Balunas MJ, Gerwick WH, Spadafora A, Gutiérrez M, Spadafora C.

PLoS One. 2019 Apr 2;14(4):e0214193. doi: 10.1371/journal.pone.0214193. eCollection 2019.

2.

Aqueous and methanol extracts of Paullinia pinnata L. (Sapindaceae) improve inflammation, pain and histological features in CFA-induced mono-arthritis: Evidence from in vivo and in vitro studies.

Tseuguem PP, Ngangoum DAM, Pouadjeu JM, Piégang BN, Sando Z, Kolber BJ, Tidgewell KJ, Nguelefack TB.

J Ethnopharmacol. 2019 May 23;236:183-195. doi: 10.1016/j.jep.2019.02.048. Epub 2019 Mar 5.

PMID:
30849505
3.

Evaluating Marine Cyanobacteria as a Source for CNS Receptor Ligands.

Rague AL, Parker SJ, Tidgewell KJ.

Molecules. 2018 Oct 17;23(10). pii: E2665. doi: 10.3390/molecules23102665.

4.

Cyanobacterial extract with serotonin receptor subtype 7 (5-HT7 R) affinity modulates depression and anxiety-like behavior in mice.

Lax NC, Parker SJ, Hilton EJ, Seliman Y, Tidgewell KJ, Kolber BJ.

Synapse. 2018 Nov;72(11):e22059. doi: 10.1002/syn.22059. Epub 2018 Aug 21.

5.

Development and Implementation of a Global Health Elective with a Drug Discovery Game for Pharmacy Students.

Covvey JR, Guarascio AJ, O'Donnell LA, Tidgewell KJ.

Pharmacy (Basel). 2017 Aug 28;5(3). pii: E49. doi: 10.3390/pharmacy5030049.

6.

Pharmacophore Comparison and Development of Recently Discovered Long Chain Arylpiperazine and Sulfonamide Based 5-HT7 Ligands.

Rague A, Tidgewell K.

Mini Rev Med Chem. 2018;18(7):552-560. doi: 10.2174/1389557517666170913111533. Review.

7.

Marine cyanobacteria-derived serotonin receptor 2C active fraction induces psychoactive behavioral effects in mice.

Lax NC, Ahmed KT, Ignatz CM, Spadafora C, Kolber BJ, Tidgewell KJ.

Pharm Biol. 2016 Nov;54(11):2723-2731. Epub 2016 May 14.

8.

Summer undergraduate research: A new pipeline for pain clinical practice and research.

Kolber BJ, Janjic JM, Pollock JA, Tidgewell KJ.

BMC Med Educ. 2016 May 4;16:135. doi: 10.1186/s12909-016-0648-7.

9.

Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins.

Balunas MJ, Grosso MF, Villa FA, Engene N, McPhail KL, Tidgewell K, Pineda LM, Gerwick L, Spadafora C, Kyle DE, Gerwick WH.

Org Lett. 2012 Aug 3;14(15):3878-81. Epub 2012 Jul 13.

10.

Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology.

Lamb K, Tidgewell K, Simpson DS, Bohn LM, Prisinzano TE.

Drug Alcohol Depend. 2012 Mar 1;121(3):181-8. doi: 10.1016/j.drugalcdep.2011.10.026. Epub 2011 Nov 26.

11.

Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii.

Tidgewell K, Engene N, Byrum T, Media J, Doi T, Valeriote FA, Gerwick WH.

Chembiochem. 2010 Jul 5;11(10):1458-66. doi: 10.1002/cbic.201000070.

12.

Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula.

Gutiérrez M, Tidgewell K, Capson TL, Engene N, Almanza A, Schemies J, Jung M, Gerwick WH.

J Nat Prod. 2010 Apr 23;73(4):709-11. doi: 10.1021/np9005184.

13.

Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity.

Balunas MJ, Linington RG, Tidgewell K, Fenner AM, Ureña LD, Togna GD, Kyle DE, Gerwick WH.

J Nat Prod. 2010 Jan;73(1):60-6. doi: 10.1021/np900622m.

14.

Herkinorin analogues with differential beta-arrestin-2 interactions.

Tidgewell K, Groer CE, Harding WW, Lozama A, Schmidt M, Marquam A, Hiemstra J, Partilla JS, Dersch CM, Rothman RB, Bohn LM, Prisinzano TE.

J Med Chem. 2008 Apr 24;51(8):2421-31. doi: 10.1021/jm701162g. Epub 2008 Apr 2.

15.

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: exploration of the 1-position.

Holden KG, Tidgewell K, Marquam A, Rothman RB, Navarro H, Prisinzano TE.

Bioorg Med Chem Lett. 2007 Nov 15;17(22):6111-5. Epub 2007 Sep 15.

16.

A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence.

Xu H, Partilla JS, Wang X, Rutherford JM, Tidgewell K, Prisinzano TE, Bohn LM, Rothman RB.

Synapse. 2007 Mar;61(3):166-75.

PMID:
17152090
17.

An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.

Groer CE, Tidgewell K, Moyer RA, Harding WW, Rothman RB, Prisinzano TE, Bohn LM.

Mol Pharmacol. 2007 Feb;71(2):549-57. Epub 2006 Nov 7.

18.

Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans.

Butelman ER, Mandau M, Tidgewell K, Prisinzano TE, Yuferov V, Kreek MJ.

J Pharmacol Exp Ther. 2007 Jan;320(1):300-6. Epub 2006 Oct 23.

PMID:
17060493
19.

Salvinorin A: allosteric interactions at the mu-opioid receptor.

Rothman RB, Murphy DL, Xu H, Godin JA, Dersch CM, Partilla JS, Tidgewell K, Schmidt M, Prisinzano TE.

J Pharmacol Exp Ther. 2007 Feb;320(2):801-10. Epub 2006 Oct 23.

PMID:
17060492
20.

Synthesis of salvinorin A analogues as opioid receptor probes.

Tidgewell K, Harding WW, Lozama A, Cobb H, Shah K, Kannan P, Dersch CM, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE.

J Nat Prod. 2006 Jun;69(6):914-8.

PMID:
16792410
21.

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring.

Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Dersch CM, Rothman RB, Prisinzano TE.

Bioorg Med Chem Lett. 2006 Jun 15;16(12):3170-4. Epub 2006 Apr 18.

PMID:
16621556
22.

Synthetic studies of neoclerodane diterpenes from Salvia divinorum: semisynthesis of salvinicins A and B and other chemical transformations of salvinorin A.

Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Gilmour B, Navarro H, Rothman RB, Prisinzano TE.

J Nat Prod. 2006 Jan;69(1):107-12.

23.

Kappa opioids as potential treatments for stimulant dependence.

Prisinzano TE, Tidgewell K, Harding WW.

AAPS J. 2005 Oct 19;7(3):E592-9. Review.

24.

Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates.

Schmidt MD, Schmidt MS, Butelman ER, Harding WW, Tidgewell K, Murry DJ, Kreek MJ, Prisinzano TE.

Synapse. 2005 Dec 1;58(3):208-10.

PMID:
16138318
25.

Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.

Harding WW, Tidgewell K, Byrd N, Cobb H, Dersch CM, Butelman ER, Rothman RB, Prisinzano TE.

J Med Chem. 2005 Jul 28;48(15):4765-71.

PMID:
16033256
26.

Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum.

Harding WW, Tidgewell K, Schmidt M, Shah K, Dersch CM, Snyder J, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE.

Org Lett. 2005 Jul 7;7(14):3017-20.

27.

Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization.

Schmidt MS, Prisinzano TE, Tidgewell K, Harding W, Butelman ER, Kreek MJ, Murry DJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Apr 25;818(2):221-5.

PMID:
15734162
28.

A facile method for the preparation of deuterium labeled salvinorin A: synthesis of [2,2,2-2H3]-salvinorin A.

Tidgewell K, Harding WW, Schmidt M, Holden KG, Murry DJ, Prisinzano TE.

Bioorg Med Chem Lett. 2004 Oct 18;14(20):5099-102.

PMID:
15380207

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