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Items: 6

1.

PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.

Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W.

Cancer Discov. 2019 Sep;9(9):1306-1323. doi: 10.1158/2159-8290.CD-18-0083. Epub 2019 Jun 19.

PMID:
31217297
2.

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells.

Hawley SA, Ross FA, Gowans GJ, Tibarewal P, Leslie NR, Hardie DG.

Biochem J. 2014 Apr 15;459(2):275-87. doi: 10.1042/BJ20131344.

3.

The PTEN and Myotubularin phosphoinositide 3-phosphatases: linking lipid signalling to human disease.

Davies EM, Sheffield DA, Tibarewal P, Fedele CG, Mitchell CA, Leslie NR.

Subcell Biochem. 2012;58:281-336. doi: 10.1007/978-94-007-3012-0_8.

PMID:
22403079
4.

PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity.

Tibarewal P, Zilidis G, Spinelli L, Schurch N, Maccario H, Gray A, Perera NM, Davidson L, Barton GJ, Leslie NR.

Sci Signal. 2012 Feb 28;5(213):ra18. doi: 10.1126/scisignal.2002138.

5.

Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN.

Davidson L, Maccario H, Perera NM, Yang X, Spinelli L, Tibarewal P, Glancy B, Gray A, Weijer CJ, Downes CP, Leslie NR.

Oncogene. 2010 Feb 4;29(5):687-97. doi: 10.1038/onc.2009.384. Epub 2009 Nov 16.

6.

Indirect mechanisms of carcinogenesis via downregulation of PTEN function.

Leslie NR, Spinelli L, Tibarewal P, Zilidis G, Weerasinghe N, Lim JC, Maccario H, Downes CP.

Adv Enzyme Regul. 2010;50(1):112-8. doi: 10.1016/j.advenzreg.2009.10.015. Epub 2009 Nov 4. Review. No abstract available.

PMID:
19895830

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