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Items: 20

1.

Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2.

Loftin CD, Tiano HF, Langenbach R.

Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:177-85. Review.

PMID:
12432917
2.

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.

Tiano HF, Loftin CD, Akunda J, Lee CA, Spalding J, Sessoms A, Dunson DB, Rogan EG, Morham SG, Smart RC, Langenbach R.

Cancer Res. 2002 Jun 15;62(12):3395-401.

4.

Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2.

Loftin CD, Trivedi DB, Tiano HF, Clark JA, Lee CA, Epstein JA, Morham SG, Breyer MD, Nguyen M, Hawkins BM, Goulet JL, Smithies O, Koller BH, Langenbach R.

Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1059-64. Epub 2001 Jan 23.

5.

Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.

Chulada PC, Thompson MB, Mahler JF, Doyle CM, Gaul BW, Lee C, Tiano HF, Morham SG, Smithies O, Langenbach R.

Cancer Res. 2000 Sep 1;60(17):4705-8.

6.

Genetic evidence for distinct roles of COX-1 and COX-2 in the immediate and delayed phases of prostaglandin synthesis in mast cells.

Reddy ST, Tiano HF, Langenbach R, Morham SG, Herschman HR.

Biochem Biophys Res Commun. 1999 Nov;265(1):205-10.

PMID:
10548515
7.

Allergic lung responses are increased in prostaglandin H synthase-deficient mice.

Gavett SH, Madison SL, Chulada PC, Scarborough PE, Qu W, Boyle JE, Tiano HF, Lee CA, Langenbach R, Roggli VL, Zeldin DC.

J Clin Invest. 1999 Sep;104(6):721-32.

8.

Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta.

Davis BJ, Lennard DE, Lee CA, Tiano HF, Morham SG, Wetsel WC, Langenbach R.

Endocrinology. 1999 Jun;140(6):2685-95.

PMID:
10342859
9.

Disruption of the mouse cyclooxygenase 1 gene. Characteristics of the mutant and areas of future study.

Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, Mahler JF, Davis BJ, Lee CA.

Adv Exp Med Biol. 1997;407:87-92.

PMID:
9321936
10.

Relative activities of retrovirally expressed murine prostaglandin synthase-1 and -2 depend on source of arachidonic acid.

Chulada PC, Loftin CD, Winn VD, Young DA, Tiano HF, Eling TE, Langenbach R.

Arch Biochem Biophys. 1996 Jun 15;330(2):301-13.

PMID:
8660660
11.

4-Ipomeanol and 2-aminoanthracene cytotoxicity in C3H/10T1/2 cells expressing rabbit cytochrome P450 4B1.

Smith PB, Tiano HF, Nesnow S, Boyd MR, Philpot RM, Langenbach R.

Biochem Pharmacol. 1995 Nov 9;50(10):1567-75.

PMID:
7503758
12.

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

Langenbach R, Morham SG, Tiano HF, Loftin CD, Ghanayem BI, Chulada PC, Mahler JF, Lee CA, Goulding EH, Kluckman KD, Kim HS, Smithies O.

Cell. 1995 Nov 3;83(3):483-92.

13.

Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

Morham SG, Langenbach R, Loftin CD, Tiano HF, Vouloumanos N, Jennette JC, Mahler JF, Kluckman KD, Ledford A, Lee CA, Smithies O.

Cell. 1995 Nov 3;83(3):473-82.

14.

Human CYP2A6 activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): mutational specificity in the gpt gene of AS52 cells.

Tiano HF, Wang RL, Hosokawa M, Crespi C, Tindall KR, Langenbach R.

Carcinogenesis. 1994 Dec;15(12):2859-66.

PMID:
8001247
15.

N-nitrosodiethylamine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced morphological transformation of C3H/10T1/2CL8 cells expressing human cytochrome P450 2A6.

Nesnow S, Beck S, Rosenblum S, Lasley J, Tiano HF, Hosokawa M, Crespi CL, Langenbach R.

Mutat Res. 1994 Jul;324(3):93-102.

PMID:
8022436
16.

Retroviral mediated expression of human cytochrome P450 2A6 in C3H/10T1/2 cells confers transformability by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Tiano HF, Hosokawa M, Chulada PC, Smith PB, Wang RL, Gonzalez FJ, Crespi CL, Langenbach R.

Carcinogenesis. 1993 Jul;14(7):1421-7.

PMID:
8330360
17.

Genetic control of chromosome synapsis in yeast meiosis.

Giroux CN, Dresser ME, Tiano HF.

Genome. 1989;31(1):88-94.

PMID:
2687110
18.

Protein structure and gene organization of mouse lactate dehydrogenase-A isozyme.

Li SS, Tiano HF, Fukasawa KM, Yagi K, Shimizu M, Sharief FS, Nakashima Y, Pan YE.

Eur J Biochem. 1985 Jun 3;149(2):215-25.

19.
20.

Isolation and characterization of a cDNA and a pseudogene for mouse lactate dehydrogenase-A isozyme.

Akai K, Yagi K, Tiano HF, Pan YC, Shimizu M, Fong K, Jungmann RA, Li SS.

Int J Biochem. 1985;17(5):645-8.

PMID:
2993055

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