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Items: 35


STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.

Moore F, Naamane N, Colli ML, Bouckenooghe T, Ortis F, Gurzov EN, Igoillo-Esteve M, Mathieu C, Bontempi G, Thykjaer T, Ørntoft TF, Eizirik DL.

J Biol Chem. 2011 Jan 14;286(2):929-41. doi: 10.1074/jbc.M110.162131. Epub 2010 Oct 27.


Identification of a novel locus for a USH3 like syndrome combined with congenital cataract.

Dad S, Østergaard E, Thykjaer T, Albrectsen A, Ravn K, Rosenberg T, Møller LB.

Clin Genet. 2010 Oct;78(4):388-97. doi: 10.1111/j.1399-0004.2010.01393.x.


Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.

Ortis F, Naamane N, Flamez D, Ladrière L, Moore F, Cunha DA, Colli ML, Thykjaer T, Thorsen K, Orntoft TF, Eizirik DL.

Diabetes. 2010 Feb;59(2):358-74. doi: 10.2337/db09-1159. Epub 2009 Nov 23.


Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells.

Herbsleb M, Birkenkamp-Demtroder K, Thykjaer T, Wiuf C, Hein AM, Orntoft TF, Dyrskjøt L.

BMC Med Genomics. 2008 Jul 22;1:31. doi: 10.1186/1755-8794-1-31.


Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situ in the urinary bladder.

Herbsleb M, Christensen OF, Thykjaer T, Wiuf C, Borre M, Orntoft TF, Dyrskjøt L.

BMC Cancer. 2008 Jan 31;8:37. doi: 10.1186/1471-2407-8-37.


Isolation of microarray-grade total RNA, microRNA, and DNA from a single PAXgene blood RNA tube.

Kruhøffer M, Dyrskjøt L, Voss T, Lindberg RL, Wyrich R, Thykjaer T, Orntoft TF.

J Mol Diagn. 2007 Sep;9(4):452-8. Epub 2007 Aug 9.


The relation between survival and expression of HER1 and HER2 depends on the expression of HER3 and HER4: a study in bladder cancer patients.

Memon AA, Sorensen BS, Meldgaard P, Fokdal L, Thykjaer T, Nexo E.

Br J Cancer. 2006 Jun 5;94(11):1703-9.


SOX4 expression in bladder carcinoma: clinical aspects and in vitro functional characterization.

Aaboe M, Birkenkamp-Demtroder K, Wiuf C, Sørensen FB, Thykjaer T, Sauter G, Jensen KM, Dyrskjøt L, Ørntoft T.

Cancer Res. 2006 Apr 1;66(7):3434-42.


Gene expression profiling of noninvasive primary urothelial tumours using microarrays.

Aaboe M, Marcussen N, Jensen KM, Thykjaer T, Dyrskjøt L, Orntoft TF.

Br J Cancer. 2005 Nov 14;93(10):1182-90.


Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells.

Enver T, Soneji S, Joshi C, Brown J, Iborra F, Orntoft T, Thykjaer T, Maltby E, Smith K, Abu Dawud R, Jones M, Matin M, Gokhale P, Draper J, Andrews PW.

Hum Mol Genet. 2005 Nov 1;14(21):3129-40. Epub 2005 Sep 13.


Gene expression signatures for colorectal cancer microsatellite status and HNPCC.

Kruhøffer M, Jensen JL, Laiho P, Dyrskjøt L, Salovaara R, Arango D, Birkenkamp-Demtroder K, Sørensen FB, Christensen LL, Buhl L, Mecklin JP, Järvinen H, Thykjaer T, Wikman FP, Bech-Knudsen F, Juhola M, Nupponen NN, Laurberg S, Andersen CL, Aaltonen LA, Ørntoft TF.

Br J Cancer. 2005 Jun 20;92(12):2240-8.


A molecular signature in superficial bladder carcinoma predicts clinical outcome.

Dyrskjøt L, Zieger K, Kruhøffer M, Thykjaer T, Jensen JL, Primdahl H, Aziz N, Marcussen N, Møller K, Orntoft TF.

Clin Cancer Res. 2005 Jun 1;11(11):4029-36.


Down-regulation of S100C is associated with bladder cancer progression and poor survival.

Memon AA, Sorensen BS, Meldgaard P, Fokdal L, Thykjaer T, Nexo E.

Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):606-11.


Expression of HER3, HER4 and their ligand heregulin-4 is associated with better survival in bladder cancer patients.

Memon AA, Sorensen BS, Melgard P, Fokdal L, Thykjaer T, Nexo E.

Br J Cancer. 2004 Dec 13;91(12):2034-41.


Preferential response of cancer cells to zebularine.

Cheng JC, Yoo CB, Weisenberger DJ, Chuang J, Wozniak C, Liang G, Marquez VE, Greer S, Orntoft TF, Thykjaer T, Jones PA.

Cancer Cell. 2004 Aug;6(2):151-8.


Gene expression in the urinary bladder: a common carcinoma in situ gene expression signature exists disregarding histopathological classification.

Dyrskjøt L, Kruhøffer M, Thykjaer T, Marcussen N, Jensen JL, Møller K, Ørntoft TF.

Cancer Res. 2004 Jun 1;64(11):4040-8.


The role of mismatch repair in small-cell lung cancer cells.

Hansen LT, Thykjaer T, Ørntoft TF, Rasmussen LJ, Keller P, Spang-Thomsen M, Edmonston TB, Schmutte C, Fishel R, Petersen LN.

Eur J Cancer. 2003 Jul;39(10):1456-67.


Identifying distinct classes of bladder carcinoma using microarrays.

Dyrskjøt L, Thykjaer T, Kruhøffer M, Jensen JL, Marcussen N, Hamilton-Dutoit S, Wolf H, Orntoft TF.

Nat Genet. 2003 Jan;33(1):90-6. Epub 2002 Dec 9.


Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism.

Hilpert J, Wogensen L, Thykjaer T, Wellner M, Schlichting U, Orntoft TF, Bachmann S, Nykjaer A, Willnow TE.

Kidney Int. 2002 Nov;62(5):1672-81.


Comparison of gene expression profiling between malignant and normal plasma cells with oligonucleotide arrays.

De Vos J, Thykjaer T, Tarte K, Ensslen M, Raynaud P, Requirand G, Pellet F, Pantesco V, Rème T, Jourdan M, Rossi JF, Ørntoft T, Klein B.

Oncogene. 2002 Oct 3;21(44):6848-57.


Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts.

Tarte K, De Vos J, Thykjaer T, Zhan F, Fiol G, Costes V, Rème T, Legouffe E, Rossi JF, Shaughnessy J Jr, Ørntoft TF, Klein B.

Blood. 2002 Aug 15;100(4):1113-22.


Profile of differentially expressed genes mediated by the type III epidermal growth factor receptor mutation expressed in a small-cell lung cancer cell line.

Pedersen MW, Thykjaer T, Ørntoft TF, Damstrup L, Poulsen HS.

Br J Cancer. 2001 Oct 19;85(8):1211-8. Erratum in: Br J Cancer 2001 Dec 14;85(12):2023-5.


Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease.

Wyttenbach A, Swartz J, Kita H, Thykjaer T, Carmichael J, Bradley J, Brown R, Maxwell M, Schapira A, Orntoft TF, Kato K, Rubinsztein DC.

Hum Mol Genet. 2001 Aug 15;10(17):1829-45.


Functional analysis of the mismatch repair system in bladder cancer.

Thykjaer T, Christensen M, Clark AB, Hansen LR, Kunkel TA, Ørntoft TF.

Br J Cancer. 2001 Aug 17;85(4):568-75.


Identification of gene expression patterns in superficial and invasive human bladder cancer.

Thykjaer T, Workman C, Kruhøffer M, Demtröder K, Wolf H, Andersen LD, Frederiksen CM, Knudsen S, Orntoft TF.

Cancer Res. 2001 Mar 15;61(6):2492-9.


Evaluation of the performance of a p53 sequencing microarray chip using 140 previously sequenced bladder tumor samples.

Wikman FP, Lu ML, Thykjaer T, Olesen SH, Andersen LD, Cordon-Cardo C, Orntoft TF.

Clin Chem. 2000 Oct;46(10):1555-61.


Gene expression profiling: monitoring transcription and translation products using DNA microarrays and proteomics.

Celis JE, Kruhøffer M, Gromova I, Frederiksen C, Ostergaard M, Thykjaer T, Gromov P, Yu J, Pálsdóttir H, Magnusson N, Orntoft TF.

FEBS Lett. 2000 Aug 25;480(1):2-16. Review.


Symbiotic mutants deficient in nodule establishment identified after T-DNA transformation of Lotus japonicus.

Schauser L, Handberg K, Sandal N, Stiller J, Thykjaer T, Pajuelo E, Nielsen A, Stougaard J.

Mol Gen Genet. 1998 Sep;259(4):414-23.


Gene targeting approaches using positive-negative selection and large flanking regions.

Thykjaer T, Finnemann J, Schauser L, Christensen L, Poulsen C, Stougaard J.

Plant Mol Biol. 1997 Nov;35(4):523-30.


Organization and expression of genes in the genomic region surrounding the glutamine synthetase gene Gln1 from Lotus japonicus.

Thykjaer T, Danielsen D, She Q, Stougaard J.

Mol Gen Genet. 1997 Aug;255(6):628-36.


The maize transposable element Ac is mobile in the legume Lotus japonicus.

Thykjaer T, Stiller J, Handberg K, Jones J, Stougaard J.

Plant Mol Biol. 1995 Mar;27(5):981-93.


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