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Items: 1 to 50 of 76

1.

Inorganic co-crystal formation and thermal disproportionation in a dicyanometallate 'superperovskite'.

Hill JA, Murray CA, Tang CC, Thygesen PMM, Thompson AL, Goodwin AL.

Chem Commun (Camb). 2019 May 7;55(38):5439-5442. doi: 10.1039/c8cc10277e.

PMID:
31020306
2.

Long-Acting Human Growth Hormone Analogue by Noncovalent Albumin Binding.

Ramírez-Andersen HS, Behrens C, Buchardt J, Fels JJ, Folkesson CG, Jianhe C, Nørskov-Lauritsen L, Nielsen PF, Reslow M, Rischel C, Su J, Thygesen P, Wiberg C, Zhao X, Wenjuan X, Johansen NL.

Bioconjug Chem. 2018 Sep 19;29(9):3129-3143. doi: 10.1021/acs.bioconjchem.8b00463. Epub 2018 Aug 31.

PMID:
30168709
3.

Antibody-Mediated Neutralization of uPA Proteolytic Function Reduces Disease Progression in Mouse Arthritis Models.

Almholt K, Hebsgaard JB, Nansen A, Andersson C, Pass J, Rønø B, Thygesen P, Pelzer H, Loftager M, Lund IK, Høyer-Hansen G, Frisch T, Jensen CH, Otte KS, Søe NH, Bartels EM, Andersen M, Bliddal H, Usher PA.

J Immunol. 2018 Feb 1;200(3):957-965. doi: 10.4049/jimmunol.1701317. Epub 2017 Dec 27.

4.

Validity and completeness of rheumatoid arthritis diagnoses in the nationwide DANBIO clinical register and the Danish National Patient Registry.

Ibfelt EH, Sørensen J, Jensen DV, Dreyer L, Schiøttz-Christensen B, Thygesen PH, Colic A, Raun JL, Manilo N, Rødgaard A, Poulsen UE, Rasmussen C, Hansen T, Unger B, Pelck R, Kincses A, Nordin H, Lorenzen T, Theibich A, Jensen Hansen IM, Espesen J, Grydehøj J, Holland-Fischer M, Loft AG, Hetland ML.

Clin Epidemiol. 2017 Nov 29;9:627-632. doi: 10.2147/CLEP.S141438. eCollection 2017.

5.

Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis.

Soendergaard C, Kvist PH, Thygesen P, Reslow M, Nielsen OH, Kopchick JJ, Holm TL.

Int J Mol Sci. 2017 Sep 23;18(10). pii: E2046. doi: 10.3390/ijms18102046.

6.

Nonclinical pharmacokinetic and pharmacodynamic characterisation of somapacitan: A reversible non-covalent albumin-binding growth hormone.

Thygesen P, Andersen HS, Behrens C, Fels JJ, Nørskov-Lauritsen L, Rischel C, Johansen NL.

Growth Horm IGF Res. 2017 Aug;35:8-16. doi: 10.1016/j.ghir.2017.05.006. Epub 2017 May 24.

PMID:
28595133
7.

Potential exposure to endocrine disrupting chemicals and selected adverse pregnancy outcomes: a follow-up study of pregnant women referred for occupational counselling.

Bengtsson J, Thygesen PS, Kaerlev L, Knudsen LE, Bonde JP.

J Occup Med Toxicol. 2017 Mar 9;12:6. doi: 10.1186/s12995-017-0152-y. eCollection 2017.

8.

Orbital Dimer Model for the Spin-Glass State in Y_{2}Mo_{2}O_{7}.

Thygesen PM, Paddison JA, Zhang R, Beyer KA, Chapman KW, Playford HY, Tucker MG, Keen DA, Hayward MA, Goodwin AL.

Phys Rev Lett. 2017 Feb 10;118(6):067201. doi: 10.1103/PhysRevLett.118.067201. Epub 2017 Feb 8.

PMID:
28234510
9.

Control of Multipolar and Orbital Order in Perovskite-like [C(NH2)3]CuxCd1-x(HCOO)3 Metal-Organic Frameworks.

Evans NL, Thygesen PM, Boström HL, Reynolds EM, Collings IE, Phillips AE, Goodwin AL.

J Am Chem Soc. 2016 Aug 3;138(30):9393-6. doi: 10.1021/jacs.6b05208. Epub 2016 Jul 22.

PMID:
27414161
10.

The kidneys play a central role in the clearance of rhGH in rats.

Vestergaard B, Thygesen P, Kreilgaard M, Fels JJ, Lykkesfeldt J, Agersø H.

Eur J Pharm Sci. 2016 Apr 30;86:29-33. doi: 10.1016/j.ejps.2016.02.019. Epub 2016 Mar 2.

PMID:
26946443
11.

Translational mixed-effects PKPD modelling of recombinant human growth hormone - from hypophysectomized rat to patients.

Thorsted A, Thygesen P, Agersø H, Laursen T, Kreilgaard M.

Br J Pharmacol. 2016 Jun;173(11):1742-55. doi: 10.1111/bph.13473. Epub 2016 Apr 21.

12.

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.

Lau J, Bloch P, Schäffer L, Pettersson I, Spetzler J, Kofoed J, Madsen K, Knudsen LB, McGuire J, Steensgaard DB, Strauss HM, Gram DX, Knudsen SM, Nielsen FS, Thygesen P, Reedtz-Runge S, Kruse T.

J Med Chem. 2015 Sep 24;58(18):7370-80. doi: 10.1021/acs.jmedchem.5b00726. Epub 2015 Sep 11.

PMID:
26308095
13.

N-glycosylation increases the circulatory half-life of human growth hormone.

Flintegaard TV, Thygesen P, Rahbek-Nielsen H, Levery SB, Kristensen C, Clausen H, Bolt G.

Endocrinology. 2010 Nov;151(11):5326-36. doi: 10.1210/en.2010-0574. Epub 2010 Sep 8.

PMID:
20826563
14.

Physiologically-based PK/PD modelling of therapeutic macromolecules.

Thygesen P, Macheras P, Van Peer A.

Pharm Res. 2009 Dec;26(12):2543-50. doi: 10.1007/s11095-009-9990-3. Epub 2009 Oct 22. Review.

PMID:
19847627
15.

An open-label, two-arm, phase I trial of recombinant human interleukin-21 in patients with metastatic melanoma.

Davis ID, Skrumsager BK, Cebon J, Nicholaou T, Barlow JW, Moller NP, Skak K, Lundsgaard D, Frederiksen KS, Thygesen P, McArthur GA.

Clin Cancer Res. 2007 Jun 15;13(12):3630-6.

16.

Pharmacokinetics of trefoil peptides and their stability in gastrointestinal contents.

Kjellev S, Vestergaard EM, Nexø E, Thygesen P, Eghøj MS, Jeppesen PB, Thim L, Pedersen NB, Poulsen SS.

Peptides. 2007 Jun;28(6):1197-206. Epub 2007 Mar 31.

PMID:
17466412
17.

Interleukin 21 therapy increases the density of tumor infiltrating CD8+ T cells and inhibits the growth of syngeneic tumors.

Søndergaard H, Frederiksen KS, Thygesen P, Galsgaard ED, Skak K, Kristjansen PE, Odum N, Kragh M.

Cancer Immunol Immunother. 2007 Sep;56(9):1417-28. Epub 2007 Feb 7.

PMID:
17285290
18.

125I used for labelling of proteins in an absorption model changes the absorption rate of insulin aspart.

Sohoel A, Plum A, Frokjaer S, Thygesen P.

Int J Pharm. 2007 Feb 7;330(1-2):114-20. Epub 2006 Sep 14.

PMID:
17070660
19.

Adjuvant effect of di-n-butyl-, di-n-octyl-, di-iso-nonyl- and di-iso-decyl phthalate in a subcutaneous injection model using BALB/c mice.

Larsen ST, Lund RM, Nielsen GD, Thygesen P, Poulsen OM.

Pharmacol Toxicol. 2002 Nov;91(5):264-72.

PMID:
12570034
20.

Investigation of the adjuvant and immuno-suppressive effects of benzyl butyl phthalate, phthalic acid and benzyl alcohol in a murine injection model.

Larsen ST, Lund RM, Thygesen P, Poulsen OM, Nielsen GD.

Food Chem Toxicol. 2003 Mar;41(3):439-46.

PMID:
12504176
21.

IgE-mediated asthma and rhinitis I: a role of allergen exposure?

Nielsen GD, Hansen JS, Lund RM, Bergqvist M, Larsen ST, Clausen SK, Thygesen P, Poulsen OM.

Pharmacol Toxicol. 2002 May;90(5):231-42. Review.

PMID:
12076303
22.

Investigation of the adjuvant effect of polyethylene glycol (PEG) 400 in BALB/c mice.

Larsen ST, Nielsen GD, Thygesen P.

Int J Pharm. 2002 Jan 1;231(1):51-5.

PMID:
11719013
23.

Di-(2-ethylhexyl) phthalate possesses an adjuvant effect in a subcutaneous injection model with BALB/c mice.

Thor Larsen S, My Lund R, Damgård Nielsen G, Thygesen P, Melchior Poulsen O.

Toxicol Lett. 2001 Dec 15;125(1-3):11-8.

PMID:
11701218
24.

Adjuvant and immuno-suppressive effect of six monophthalates in a subcutaneous injection model with BALB/c mice.

Larsen ST, Hansen JS, Thygesen P, Begtrup M, Poulsen OM, Nielsen GD.

Toxicology. 2001 Dec 1;169(1):37-51.

PMID:
11696408
25.

Histologic, cytologic, and bacteriologic examinations of experimentally induced Salmonella typhimurium infection in Lewis rats.

Thygesen P, Martinsen C, Hougen HP, Hattori R, Stenvang JP, Rygaard J.

Comp Med. 2000 Apr;50(2):124-32.

PMID:
10857002
26.

Genes for human arylamine N-acetyltransferases in relation to loss of the short arm of chromosome 8 in bladder cancer.

Thygesen P, Risch A, Stacey M, Fakis G, Giannoulis F, Takle L, Knowles M, Sim E.

Pharmacogenetics. 1999 Feb;9(1):1-8.

PMID:
10208636
27.
29.
30.

Arylarnine N-acetyltransferase as a potential biornarker in bladder cancer: fluorescent in situ hybridization and irnmunohistochernistry studies.

Stacey M, Thygesen P, Stanley L, Matas N, Risch A, Sim E.

Biomarkers. 1996;1(1):55-61. doi: 10.3109/13547509609079347.

PMID:
23888894
31.

Xenogenetics in multifactorial disease susceptibility.

Sim E, Stanley LA, Risch A, Thygesen P.

Trends Genet. 1995 Dec;11(12):509-12. Review.

PMID:
8533169
32.

The isolation and characterisation of a gene encoding superoxide dismutase from Bradyrhizobium sp. (Parasponia) strain ANU289.

Thygesen PW, Whelan J, Morell MK, Day DA.

Biochem Mol Biol Int. 1995 Oct;37(3):401-12.

PMID:
8595379
33.

Polyphenol oxidase in potato. A multigene family that exhibits differential expression patterns.

Thygesen PW, Dry IB, Robinson SP.

Plant Physiol. 1995 Oct;109(2):525-31.

34.

Immunity to experimental Salmonella typhimurium infections in rats. Transfer of immunity with primed CD4+CD25high and CD4+CD25low T lymphocytes.

Thygesen P, Brandt L, Jørgensen T, Christensen HB, Hougen HP, Jensen ET, Rygaard J.

APMIS. 1994 Jul;102(7):489-94.

PMID:
7917217
35.

Athymic experimental animals in pharmaco-immunological research.

Juul P, Christensen HB, Hougen HP, Svendsen O, Thygesen P, Rygaard J.

Toxicol Lett. 1992 Dec;64-65 Spec No:85-92. Review.

PMID:
1471239
36.

Effect of immunosuppressive agents on the guanethidine-induced sympathectomy in athymic and euthymic rats.

Hougen HP, Thygesen P, Christensen HB, Rygaard J, Svendsen O, Juul P.

Int J Immunopharmacol. 1992 Aug;14(6):1113-23.

PMID:
1385339
37.

Anti-asialo GM1 antibodies prevents guanethidine-induced sympathectomy in athymic rats.

Thygesen P, Hougen HP, Christensen HB, Rygaard J, Svendsen O, Juul P.

Immunopharmacol Immunotoxicol. 1992;14(1-2):219-32.

PMID:
1597655
38.

Identification of the mononuclear cell infiltrate in the superior cervical ganglion of athymic nude and euthymic rats after guanethidine-induced sympathectomy.

Thygesen P, Hougen HP, Christensen HB, Rygaard J, Svendsen O, Juul P.

Int J Immunopharmacol. 1990;12(3):327-30.

PMID:
2184138
39.

The concentration camp syndrome.

Thygesen P.

Dan Med Bull. 1980 Nov;27(5):224-8. No abstract available.

PMID:
7449447
40.

[Creutzfeldt-Jakob disease, an infectious form of presenile dementia].

Astrup L, Thygesen P.

Ugeskr Laeger. 1979 Oct 22;141(43):2967-8. Danish. No abstract available.

PMID:
392855
41.

[142 cases of occupational poisoning with organic solvents reported to the Industrial Injuries Security Office in 1961-1970. I. Exposure].

Nielsen H, Gregersen P, Thygesen P.

Ugeskr Laeger. 1979 Sep 17;141(38):2635-9. Danish. No abstract available.

PMID:
483462
42.

[142 cases of occupational poisoning with organic solvents reported to the Industrial Injuries Security Office in 1961-70. II. Disease, disability and compensation].

Nielsen H, Gregersen P, Thygesen P.

Ugeskr Laeger. 1979 Sep 17;141(38):2639-44. Danish. No abstract available.

PMID:
158246
44.

[Chronic cerebral syndrome in painters. Dementia due to inhalation or is it of cryptogenic origin?].

Gregersen P, Mikkelsen S, Klausen H, Døssing M, Nielsen H, Thygesen P.

Ugeskr Laeger. 1978 Jul 3;140(27):1638-44. Danish. No abstract available.

PMID:
684909
45.

Familial recurrent polyneuropathy. A family and a survey.

Roos D, Thygesen P.

Brain. 1972;95(2):235-48. No abstract available.

PMID:
4347629
46.
47.

[Prophylactic treatment of migraine patients with 6-alpha-trifluoromethyl-17-alpha-acetoxyprogesterone (Demigran Leo, WG 537)].

Thygesen P, Klee A, Fog M.

Ugeskr Laeger. 1969 Jan 23;131(4):144-9. Danish. No abstract available.

PMID:
4892187
48.

Intellectual impairment and cerebral atrophy. A psychological, neurological and radiological investigation.

Willanger R, Thygesen P, Nielsen R, Petersen O.

Dan Med Bull. 1968 Mar;15(3):65-93. No abstract available.

PMID:
4876983
49.

Encephalographic cortical atrophy. Relationships to ventricular atrophy and intellectual impairment.

Nielsen R, Petersen O, Thygesen P, Willanger R.

Acta Radiol Diagn (Stockh). 1966 Jul;4(4):437-48. No abstract available.

PMID:
5296332
50.

Encephalographic ventricular atrophy. Relationships between size of ventricular system and intellectual impairment.

Nielsen R, Petersen O, Thygesen P, Willanger R.

Acta Radiol Diagn (Stockh). 1966 May;4(3):240-56. No abstract available.

PMID:
5296217

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