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Items: 32

1.

Fast LC-MS quantification of ptesculentoside, caudatoside, ptaquiloside and corresponding pterosins in bracken ferns.

Kisielius V, Lindqvist DN, Thygesen MB, Rodamer M, Hansen HCB, Rasmussen LH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Feb 1;1138:121966. doi: 10.1016/j.jchromb.2019.121966. Epub 2020 Jan 3.

2.

Ultrasmall TPGS-PLGA Hybrid Nanoparticles for Site-Specific Delivery of Antibiotics into Pseudomonas aeruginosa Biofilms in Lungs.

Wan F, Bohr SS, Kłodzińska SN, Jumaa H, Huang Z, Nylander T, Thygesen MB, Sørensen KK, Jensen KJ, Sternberg C, Hatzakis N, Mørck Nielsen H.

ACS Appl Mater Interfaces. 2020 Jan 8;12(1):380-389. doi: 10.1021/acsami.9b19644. Epub 2019 Dec 17.

PMID:
31804792
3.

A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula.

Feng F, Sun J, Radhakrishnan GV, Lee T, Bozsóki Z, Fort S, Gavrin A, Gysel K, Thygesen MB, Andersen KR, Radutoiu S, Stougaard J, Oldroyd GED.

Nat Commun. 2019 Nov 6;10(1):5047. doi: 10.1038/s41467-019-12999-5.

4.

A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis.

Malolepszy A, Kelly S, Sørensen KK, James EK, Kalisch C, Bozsoki Z, Panting M, Andersen SU, Sato S, Tao K, Jensen DB, Vinther M, Jong N, Madsen LH, Umehara Y, Gysel K, Berentsen MU, Blaise M, Jensen KJ, Thygesen MB, Sandal N, Andersen KR, Radutoiu S.

Elife. 2018 Oct 4;7. pii: e38874. doi: 10.7554/eLife.38874.

5.

Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence.

Martos-Maldonado MC, Hjuler CT, Sørensen KK, Thygesen MB, Rasmussen JE, Villadsen K, Midtgaard SR, Kol S, Schoffelen S, Jensen KJ.

Nat Commun. 2018 Aug 17;9(1):3307. doi: 10.1038/s41467-018-05695-3.

6.

Epidermal LysM receptor ensures robust symbiotic signalling in Lotus japonicus.

Murakami E, Cheng J, Gysel K, Bozsoki Z, Kawaharada Y, Hjuler CT, Sørensen KK, Tao K, Kelly S, Venice F, Genre A, Thygesen MB, Jong N, Vinther M, Jensen DB, Jensen KJ, Blaise M, Madsen LH, Andersen KR, Stougaard J, Radutoiu S.

Elife. 2018 Jun 29;7. pii: e33506. doi: 10.7554/eLife.33506.

7.

Structures of exopolysaccharides involved in receptor-mediated perception of Mesorhizobium loti by Lotus japonicas.

Muszyński A, Heiss C, Hjuler CT, Sullivan JT, Kelly SJ, Thygesen MB, Stougaard J, Azadi P, Carlson RW, Ronson CW.

J Biol Chem. 2018 Apr 6;293(14):5376. doi: 10.1074/jbc.AAC118.002877. No abstract available.

PMID:
29626109
Free PMC Article
8.

Glycoconjugate Oxime Formation Catalyzed at Neutral pH: Mechanistic Insights and Applications of 1,4-Diaminobenzene as a Superior Catalyst for Complex Carbohydrates.

Østergaard M, Christensen NJ, Hjuler CT, Jensen KJ, Thygesen MB.

Bioconjug Chem. 2018 Apr 18;29(4):1219-1230. doi: 10.1021/acs.bioconjchem.8b00019. Epub 2018 Feb 27.

PMID:
29437382
9.

Preparation of glycoconjugates from unprotected carbohydrates for protein-binding studies.

Hjuler CT, Maolanon NN, Sauer J, Stougaard J, Thygesen MB, Jensen KJ.

Nat Protoc. 2017 Nov;12(11):2411-2422. doi: 10.1038/nprot.2017.109. Epub 2017 Oct 26.

PMID:
29072708
10.

Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues.

Bech EM, Martos-Maldonado MC, Wismann P, Sørensen KK, van Witteloostuijn SB, Thygesen MB, Vrang N, Jelsing J, Pedersen SL, Jensen KJ.

J Med Chem. 2017 Sep 14;60(17):7434-7446. doi: 10.1021/acs.jmedchem.7b00787. Epub 2017 Aug 16.

PMID:
28771355
11.

Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates.

Villadsen K, Martos-Maldonado MC, Jensen KJ, Thygesen MB.

Chembiochem. 2017 Apr 4;18(7):574-612. doi: 10.1002/cbic.201600582. Epub 2017 Mar 1. Review.

PMID:
28067438
12.

Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy.

van Witteloostuijn SB, Mannerstedt K, Wismann P, Bech EM, Thygesen MB, Vrang N, Jelsing J, Jensen KJ, Pedersen SL.

Mol Pharm. 2017 Jan 3;14(1):193-205. doi: 10.1021/acs.molpharmaceut.6b00787. Epub 2016 Dec 22.

PMID:
28005376
13.

Structures of Exopolysaccharides Involved in Receptor-mediated Perception of Mesorhizobium loti by Lotus japonicus.

Muszyński A, Heiss C, Hjuler CT, Sullivan JT, Kelly SJ, Thygesen MB, Stougaard J, Azadi P, Carlson RW, Ronson CW.

J Biol Chem. 2016 Sep 30;291(40):20946-20961. Epub 2016 Aug 8. Erratum in: J Biol Chem. 2018 Apr 6;293(14 ):5376.

14.

Grafted biomembranes containing membrane proteins--the case of the leucine transporter.

Jagalski V, Barker RD, Thygesen MB, Gotfryd K, Krüger MB, Shi L, Maric S, Bovet N, Moulin M, Haertlein M, Pomorski TG, Loland CJ, Cárdenas M.

Soft Matter. 2015 Oct 21;11(39):7707-11. doi: 10.1039/c5sm01490e. Epub 2015 Sep 1.

PMID:
26325086
15.

Receptor-mediated exopolysaccharide perception controls bacterial infection.

Kawaharada Y, Kelly S, Nielsen MW, Hjuler CT, Gysel K, Muszyński A, Carlson RW, Thygesen MB, Sandal N, Asmussen MH, Vinther M, Andersen SU, Krusell L, Thirup S, Jensen KJ, Ronson CW, Blaise M, Radutoiu S, Stougaard J.

Nature. 2015 Jul 16;523(7560):308-12. doi: 10.1038/nature14611. Epub 2015 Jul 8.

PMID:
26153863
16.

Antimicrobial peptide shows enhanced activity and reduced toxicity upon grafting to chitosan polymers.

Sahariah P, Sørensen KK, Hjálmarsdóttir MÁ, Sigurjónsson ÓE, Jensen KJ, Másson M, Thygesen MB.

Chem Commun (Camb). 2015 Jul 25;51(58):11611-4. doi: 10.1039/c5cc04010h. Epub 2015 Jun 22.

PMID:
26096124
17.

Impact of chain length on antibacterial activity and hemocompatibility of quaternary N-alkyl and n,n-dialkyl chitosan derivatives.

Sahariah P, Benediktssdóttir BE, Hjálmarsdóttir MÁ, Sigurjonsson OE, Sørensen KK, Thygesen MB, Jensen KJ, Másson M.

Biomacromolecules. 2015 May 11;16(5):1449-60. doi: 10.1021/acs.biomac.5b00163. Epub 2015 Apr 16.

PMID:
25830631
18.

An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase.

Wong JE, Midtgaard SR, Gysel K, Thygesen MB, Sørensen KK, Jensen KJ, Stougaard J, Thirup S, Blaise M.

Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):592-605. doi: 10.1107/S139900471402793X. Epub 2015 Feb 26.

19.

Switching of bacterial adhesion to a glycosylated surface by reversible reorientation of the carbohydrate ligand.

Weber T, Chandrasekaran V, Stamer I, Thygesen MB, Terfort A, Lindhorst TK.

Angew Chem Int Ed Engl. 2014 Dec 22;53(52):14583-6. doi: 10.1002/anie.201409808. Epub 2014 Nov 27.

PMID:
25429860
20.

Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli.

Maric S, Thygesen MB, Schiller J, Marek M, Moulin M, Haertlein M, Forsyth VT, Bogdanov M, Dowhan W, Arleth L, Pomorski TG.

Appl Microbiol Biotechnol. 2015 Jan;99(1):241-54. doi: 10.1007/s00253-014-6082-z. Epub 2014 Oct 11.

21.

Stealth carriers for low-resolution structure determination of membrane proteins in solution.

Maric S, Skar-Gislinge N, Midtgaard S, Thygesen MB, Schiller J, Frielinghaus H, Moulin M, Haertlein M, Forsyth VT, Pomorski TG, Arleth L.

Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):317-28. doi: 10.1107/S1399004713027466. Epub 2014 Jan 29.

PMID:
24531466
22.

Lipochitin oligosaccharides immobilized through oximes in glycan microarrays bind LysM proteins.

Maolanon NN, Blaise M, Sørensen KK, Thygesen MB, Cló E, Sullivan JT, Ronson CW, Stougaard J, Blixt O, Jensen KJ.

Chembiochem. 2014 Feb 10;15(3):425-34. doi: 10.1002/cbic.201300520. Epub 2014 Jan 16.

PMID:
24436194
23.

Kinetic analysis of inhibition of glucoamylase and active site mutants via chemoselective oxime immobilization of acarbose on SPR chip surfaces.

Sauer J, Abou Hachem M, Svensson B, Jensen KJ, Thygesen MB.

Carbohydr Res. 2013 Jun 28;375:21-8. doi: 10.1016/j.carres.2013.04.012. Epub 2013 Apr 20.

PMID:
23680647
24.

Regioselective fluorescent labeling of N,N,N-trimethyl chitosan via oxime formation.

Benediktsdóttir BE, Sørensen KK, Thygesen MB, Jensen KJ, Gudjónsson T, Baldursson O, Másson M.

Carbohydr Polym. 2012 Oct 15;90(3):1273-80. doi: 10.1016/j.carbpol.2012.06.070. Epub 2012 Jul 1.

PMID:
22939341
25.

Legume receptors perceive the rhizobial lipochitin oligosaccharide signal molecules by direct binding.

Broghammer A, Krusell L, Blaise M, Sauer J, Sullivan JT, Maolanon N, Vinther M, Lorentzen A, Madsen EB, Jensen KJ, Roepstorff P, Thirup S, Ronson CW, Thygesen MB, Stougaard J.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13859-64. doi: 10.1073/pnas.1205171109. Epub 2012 Aug 2.

26.

Nucleophilic catalysis of carbohydrate oxime formation by anilines.

Thygesen MB, Munch H, Sauer J, Cló E, Jørgensen MR, Hindsgaul O, Jensen KJ.

J Org Chem. 2010 Mar 5;75(5):1752-5. doi: 10.1021/jo902425v.

PMID:
20131837
27.

Improved characterization of nod factors and genetically based variation in LysM Receptor domains identify amino acids expendable for nod factor recognition in Lotus spp.

Bek AS, Sauer J, Thygesen MB, Duus JØ, Petersen BO, Thirup S, James E, Jensen KJ, Stougaard J, Radutoiu S.

Mol Plant Microbe Interact. 2010 Jan;23(1):58-66. doi: 10.1094/MPMI-23-1-0058.

28.

Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators.

Schlienger N, Lund BW, Pawlas J, Badalassi F, Bertozzi F, Lewinsky R, Fejzic A, Thygesen MB, Tabatabaei A, Bradley SR, Gardell LR, Piu F, Olsson R.

J Med Chem. 2009 Nov 26;52(22):7186-91. doi: 10.1021/jm901149c.

PMID:
19856921
29.

Direct chemoselective synthesis of glyconanoparticles from unprotected reducing glycans and glycopeptide aldehydes.

Thygesen MB, Sørensen KK, Cló E, Jensen KJ.

Chem Commun (Camb). 2009 Nov 14;(42):6367-9. doi: 10.1039/b911676a. Epub 2009 Oct 1.

PMID:
19841779
30.

Chemoselective capture of glycans for analysis on gold nanoparticles: carbohydrate oxime tautomers provide functional recognition by proteins.

Thygesen MB, Sauer J, Jensen KJ.

Chemistry. 2009;15(7):1649-60. doi: 10.1002/chem.200801521.

PMID:
19115306
31.

Solid-phase chemical tools for glycobiology.

Larsen K, Thygesen MB, Guillaumie F, Willats WG, Jensen KJ.

Carbohydr Res. 2006 Jul 24;341(10):1209-34. Epub 2006 May 22. Review.

PMID:
16716275
32.

Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist.

Vanover KE, Weiner DM, Makhay M, Veinbergs I, Gardell LR, Lameh J, Del Tredici AL, Piu F, Schiffer HH, Ott TR, Burstein ES, Uldam AK, Thygesen MB, Schlienger N, Andersson CM, Son TY, Harvey SC, Powell SB, Geyer MA, Tolf BR, Brann MR, Davis RE.

J Pharmacol Exp Ther. 2006 May;317(2):910-8. Epub 2006 Feb 9.

PMID:
16469866

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