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Thiol-Gelatin-Norbornene Bioink for Laser-Based High-Definition Bioprinting.

Dobos A, Van Hoorick J, Steiger W, Gruber P, Markovic M, Andriotis OG, Rohatschek A, Dubruel P, Thurner PJ, Van Vlierberghe S, Baudis S, Ovsianikov A.

Adv Healthc Mater. 2019 Jul 26:e1900752. doi: 10.1002/adhm.201900752. [Epub ahead of print]


Hydration and nanomechanical changes in collagen fibrils bearing advanced glycation end-products.

Andriotis OG, Elsayad K, Smart DE, Nalbach M, Davies DE, Thurner PJ.

Biomed Opt Express. 2019 Mar 14;10(4):1841-1855. doi: 10.1364/BOE.10.001841. eCollection 2019 Apr 1.


A Modular Approach to Sensitized Two-Photon Patterning of Photodegradable Hydrogels.

Lunzer M, Shi L, Andriotis OG, Gruber P, Markovic M, Thurner PJ, Ossipov D, Liska R, Ovsianikov A.

Angew Chem Int Ed Engl. 2018 Nov 12;57(46):15122-15127. doi: 10.1002/anie.201808908. Epub 2018 Oct 18.


Dehydration of individual bovine trabeculae causes transition from ductile to quasi-brittle failure mode.

Frank M, Marx D, Nedelkovski V, Fischer JT, Pahr DH, Thurner PJ.

J Mech Behav Biomed Mater. 2018 Nov;87:296-305. doi: 10.1016/j.jmbbm.2018.07.039. Epub 2018 Aug 1.


Evaluation of surface charge shift of collagen fibrils exposed to glutaraldehyde.

Mesquida P, Kohl D, Andriotis OG, Thurner PJ, Duer M, Bansode S, Schitter G.

Sci Rep. 2018 Jul 4;8(1):10126. doi: 10.1038/s41598-018-28293-1.


Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis.

Jones MG, Andriotis OG, Roberts JJ, Lunn K, Tear VJ, Cao L, Ask K, Smart DE, Bonfanti A, Johnson P, Alzetani A, Conforti F, Doherty R, Lai CY, Johnson B, Bourdakos KN, Fletcher SV, Marshall BG, Jogai S, Brereton CJ, Chee SJ, Ottensmeier CH, Sime P, Gauldie J, Kolb M, Mahajan S, Fabre A, Bhaskar A, Jarolimek W, Richeldi L, O'Reilly KM, Monk PD, Thurner PJ, Davies DE.

Elife. 2018 Jul 3;7. pii: e36354. doi: 10.7554/eLife.36354.


Calibration of colloidal probes with atomic force microscopy for micromechanical assessment.

Kain L, Andriotis OG, Gruber P, Frank M, Markovic M, Grech D, Nedelkovski V, Stolz M, Ovsianikov A, Thurner PJ.

J Mech Behav Biomed Mater. 2018 Sep;85:225-236. doi: 10.1016/j.jmbbm.2018.05.026. Epub 2018 May 17.


Collective Cell Behavior in Mechanosensing of Substrate Thickness.

Tusan CG, Man YH, Zarkoob H, Johnston DA, Andriotis OG, Thurner PJ, Yang S, Sander EA, Gentleman E, Sengers BG, Evans ND.

Biophys J. 2018 Jun 5;114(11):2743-2755. doi: 10.1016/j.bpj.2018.03.037.


Regional diversity in the murine cortical vascular network is revealed by synchrotron X-ray tomography and is amplified with age.

Núñez JA, Goring A, Javaheri B, Razi H, Gomez-Nicola D, Pitsillides AA, Thurner PJ, Gomez-Nicola D, Schneider P, Clarkin CE.

Eur Cell Mater. 2018 May 23;35:281-299. doi: 10.22203/eCM.v035a20.


Collagen Fibrils: Nature's Highly Tunable Nonlinear Springs.

Andriotis OG, Desissaire S, Thurner PJ.

ACS Nano. 2018 Apr 24;12(4):3671-3680. doi: 10.1021/acsnano.8b00837. Epub 2018 Mar 21.


Structure and collagen crimp patterns of functionally distinct equine tendons, revealed by quantitative polarised light microscopy (qPLM).

Spiesz EM, Thorpe CT, Thurner PJ, Screen HRC.

Acta Biomater. 2018 Apr 1;70:281-292. doi: 10.1016/j.actbio.2018.01.034. Epub 2018 Feb 2.


Simultaneous visualisation of calcified bone microstructure and intracortical vasculature using synchrotron X-ray phase contrast-enhanced tomography.

Núñez JA, Goring A, Hesse E, Thurner PJ, Schneider P, Clarkin CE.

Sci Rep. 2017 Oct 16;7(1):13289. doi: 10.1038/s41598-017-13632-5.


The inferomedial femoral neck is compromised by age but not disease: Fracture toughness and the multifactorial mechanisms comprising reference point microindentation.

Jenkins T, Katsamenis OL, Andriotis OG, Coutts LV, Carter B, Dunlop DG, Oreffo ROC, Cooper C, Harvey NC, Thurner PJ, The OStEO Group.

J Mech Behav Biomed Mater. 2017 Nov;75:399-412. doi: 10.1016/j.jmbbm.2017.06.036. Epub 2017 Jun 30.


Differentiation of Intrahepatic Cholangiocellular Carcinoma from Hepatocellular Carcinoma in the Cirrhotic Liver Using Contrast-enhanced MR Imaging.

Wengert GJ, Baltzer PAT, Bickel H, Thurner P, Breitenseher J, Lazar M, Pones M, Peck-Radosavljevic M, Hucke F, Ba-Ssalamah A.

Acad Radiol. 2017 Dec;24(12):1491-1500. doi: 10.1016/j.acra.2017.06.005. Epub 2017 Jul 26.


Elastic modulus varies along the bovine femur.

Nobakhti S, Katsamenis OL, Zaarour N, Limbert G, Thurner PJ.

J Mech Behav Biomed Mater. 2017 Jul;71:279-285. doi: 10.1016/j.jmbbm.2017.03.021. Epub 2017 Mar 27.


Respiratory motion artifacts during arterial phase imaging with gadoxetic acid: Can the injection protocol minimize this drawback?

Polanec SH, Bickel H, Baltzer PAT, Thurner P, Gittler F, Hodge JC, Bashir MR, Ba-Ssalamah A.

J Magn Reson Imaging. 2017 Oct;46(4):1107-1114. doi: 10.1002/jmri.25657. Epub 2017 Feb 9.


Development of X-ray micro-focus computed tomography to image and quantify biofilms in central venous catheter models in vitro.

Niehaus WL, Howlin RP, Johnston DA, Bull DJ, Jones GL, Calton E, Mavrogordato MN, Clarke SC, Thurner PJ, Faust SN, Stoodley P.

Microbiology. 2016 Sep;162(9):1629-1640. doi: 10.1099/mic.0.000334. Epub 2016 Jul 6.


Commentary on: Mechanical properties of cortical bone and their relationships with age, gender, composition and microindentation properties in the elderly.

Thurner PJ.

Bone. 2016 Jun;87:159-60. doi: 10.1016/j.bone.2016.04.009. Epub 2016 Apr 16. No abstract available.


Local Variation in Femoral Neck Cortical Bone: In Vitro Measured Bone Mineral Density, Geometry and Mechanical Properties.

Coutts LV, Jenkins T, Oreffo ROC, Dunlop DG, Cooper C, Harvey NC, Thurner PJ; OStEO Study Team.

J Clin Densitom. 2017 Apr - Jun;20(2):205-215. doi: 10.1016/j.jocd.2015.10.003. Epub 2015 Dec 23.


Structure-mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model.

Andriotis OG, Chang SW, Vanleene M, Howarth PH, Davies DE, Shefelbine SJ, Buehler MJ, Thurner PJ.

J R Soc Interface. 2015 Oct 6;12(111):20150701. doi: 10.1098/rsif.2015.0701.


Site-Dependent Reference Point Microindentation Complements Clinical Measures for Improved Fracture Risk Assessment at the Human Femoral Neck.

Jenkins T, Coutts LV, D'Angelo S, Dunlop DG, Oreffo RO, Cooper C, Harvey NC, Thurner PJ; Observational Study Examining Osteoporosis (OStEO) group.

J Bone Miner Res. 2016 Jan;31(1):196-203. doi: 10.1002/jbmr.2605. Epub 2015 Oct 6.


Toughness and damage susceptibility in human cortical bone is proportional to mechanical inhomogeneity at the osteonal-level.

Katsamenis OL, Jenkins T, Thurner PJ.

Bone. 2015 Jul;76:158-68. doi: 10.1016/j.bone.2015.03.020. Epub 2015 Apr 9.


Variability in reference point microindentation and recommendations for testing cortical bone: location, thickness and orientation heterogeneity.

Coutts LV, Jenkins T, Li T, Dunlop DG, Oreffo RO, Cooper C, Harvey NC, Thurner PJ; OStEO Group.

J Mech Behav Biomed Mater. 2015 Jun;46:292-304. doi: 10.1016/j.jmbbm.2015.02.004. Epub 2015 Feb 17.


An experimental and computational study of the hydrodynamics of high-velocity water microdrops for interproximal tooth cleaning.

Rmaile A, Carugo D, Capretto L, Wharton JA, Thurner PJ, Aspiras M, Ward M, De Jager M, Stoodley P.

J Mech Behav Biomed Mater. 2015 Jun;46:148-57. doi: 10.1016/j.jmbbm.2015.02.010. Epub 2015 Feb 21.


Variability in reference point microindentation and recommendations for testing cortical bone: maximum load, sample orientation, mode of use, sample preparation and measurement spacing.

Jenkins T, Coutts LV, Dunlop DG, Oreffo RO, Cooper C, Harvey NC, Thurner PJ; OStEO group.

J Mech Behav Biomed Mater. 2015 Feb;42:311-24. doi: 10.1016/j.jmbbm.2014.09.030. Epub 2014 Oct 24.


Extracellular DNA impedes the transport of vancomycin in Staphylococcus epidermidis biofilms preexposed to subinhibitory concentrations of vancomycin.

Doroshenko N, Tseng BS, Howlin RP, Deacon J, Wharton JA, Thurner PJ, Gilmore BF, Parsek MR, Stoodley P.

Antimicrob Agents Chemother. 2014 Dec;58(12):7273-82. doi: 10.1128/AAC.03132-14. Epub 2014 Sep 29.


Preparation and characterization of bioadhesive microparticles comprised of low degree of quaternization trimethylated chitosan for nasal administration: effect of concentration and molecular weight.

Karavasili C, Katsamenis OL, Bouropoulos N, Nazar H, Thurner PJ, van der Merwe SM, Fatouros DG.

Langmuir. 2014 Oct 21;30(41):12337-44. doi: 10.1021/la5030636. Epub 2014 Oct 7.


Nanomechanical assessment of human and murine collagen fibrils via atomic force microscopy cantilever-based nanoindentation.

Andriotis OG, Manuyakorn W, Zekonyte J, Katsamenis OL, Fabri S, Howarth PH, Davies DE, Thurner PJ.

J Mech Behav Biomed Mater. 2014 Nov;39:9-26. doi: 10.1016/j.jmbbm.2014.06.015. Epub 2014 Jul 15. Erratum in: J Mech Behav Biomed Mater. 2015 May;45:193.


The role of nanoscale toughening mechanisms in osteoporosis.

Thurner PJ, Katsamenis OL.

Curr Osteoporos Rep. 2014 Sep;12(3):351-6. doi: 10.1007/s11914-014-0217-0. Review.


A two-state model for the diffusion of the A2A adenosine receptor in hippocampal neurons: agonist-induced switch to slow mobility is modified by synapse-associated protein 102 (SAP102).

Thurner P, Gsandtner I, Kudlacek O, Choquet D, Nanoff C, Freissmuth M, Zezula J.

J Biol Chem. 2014 Mar 28;289(13):9263-74. doi: 10.1074/jbc.M113.505685. Epub 2014 Feb 7.


Sox17 is required for normal pulmonary vascular morphogenesis.

Lange AW, Haitchi HM, LeCras TD, Sridharan A, Xu Y, Wert SE, James J, Udell N, Thurner PJ, Whitsett JA.

Dev Biol. 2014 Mar 1;387(1):109-20. doi: 10.1016/j.ydbio.2013.11.018. Epub 2014 Jan 10.


Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine.

Thurner P, Stary-Weinzinger A, Gafar H, Gawali VS, Kudlacek O, Zezula J, Hilber K, Boehm S, Sandtner W, Koenig X.

J Pharmacol Exp Ther. 2014 Feb;348(2):346-58. doi: 10.1124/jpet.113.209643. Epub 2013 Dec 4.


Cement lines and interlamellar areas in compact bone as strain amplifiers - contributors to elasticity, fracture toughness and mechanotransduction.

Nobakhti S, Limbert G, Thurner PJ.

J Mech Behav Biomed Mater. 2014 Jan;29:235-51. doi: 10.1016/j.jmbbm.2013.09.011. Epub 2013 Sep 18.


Recruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor.

Bergmayr C, Thurner P, Keuerleber S, Kudlacek O, Nanoff C, Freissmuth M, Gruber CW.

J Biol Chem. 2013 Oct 4;288(40):28831-44. doi: 10.1074/jbc.M113.464776. Epub 2013 Aug 21.


Finite element prediction with experimental validation of damage distribution in single trabeculae during three-point bending tests.

Ridha H, Thurner PJ.

J Mech Behav Biomed Mater. 2013 Nov;27:94-106. doi: 10.1016/j.jmbbm.2013.07.005. Epub 2013 Jul 10.


Epithelial mechanobiology, skin wound healing, and the stem cell niche.

Evans ND, Oreffo RO, Healy E, Thurner PJ, Man YH.

J Mech Behav Biomed Mater. 2013 Dec;28:397-409. doi: 10.1016/j.jmbbm.2013.04.023. Epub 2013 May 14. Review.


Human anti-macrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo.

Hussain F, Freissmuth M, Völkel D, Thiele M, Douillard P, Antoine G, Thurner P, Ehrlich H, Schwarz HP, Scheiflinger F, Kerschbaumer RJ.

Mol Cancer Ther. 2013 Jul;12(7):1223-34. doi: 10.1158/1535-7163.MCT-12-0988. Epub 2013 Apr 25.


A novel videography method for generating crack-extension resistance curves in small bone samples.

Katsamenis OL, Jenkins T, Quinci F, Michopoulou S, Sinclair I, Thurner PJ.

PLoS One. 2013;8(2):e55641. doi: 10.1371/journal.pone.0055641. Epub 2013 Feb 6.


Load-bearing in cortical bone microstructure: Selective stiffening and heterogeneous strain distribution at the lamellar level.

Katsamenis OL, Chong HM, Andriotis OG, Thurner PJ.

J Mech Behav Biomed Mater. 2013 Jan;17:152-65. doi: 10.1016/j.jmbbm.2012.08.016. Epub 2012 Sep 10.


Reengineering the collision coupling and diffusion mode of the A2A-adenosine receptor: palmitoylation in helix 8 relieves confinement.

Keuerleber S, Thurner P, Gruber CW, Zezula J, Freissmuth M.

J Biol Chem. 2012 Dec 7;287(50):42104-18. doi: 10.1074/jbc.M112.393579. Epub 2012 Oct 15.


Anisotropy of bovine cortical bone tissue damage properties.

Szabó ME, Thurner PJ.

J Biomech. 2013 Jan 4;46(1):2-6. doi: 10.1016/j.jbiomech.2012.08.002. Epub 2012 Oct 12.


Similar damage initiation but different failure behavior in trabecular and cortical bone tissue.

Szabó ME, Zekonyte J, Katsamenis OL, Taylor M, Thurner PJ.

J Mech Behav Biomed Mater. 2011 Nov;4(8):1787-96. doi: 10.1016/j.jmbbm.2011.05.036. Epub 2011 Jun 6.


Site specific increase in heterogeneity of trabecular bone tissue mineral during oestrogen deficiency.

Brennan MA, Gleeson JP, Browne M, O'Brien FJ, Thurner PJ, McNamara LM.

Eur Cell Mater. 2011 May 15;21:396-406.


Local strain and damage mapping in single trabeculae during three-point bending tests.

Jungmann R, Szabo ME, Schitter G, Tang RY, Vashishth D, Hansma PK, Thurner PJ.

J Mech Behav Biomed Mater. 2011 May;4(4):523-34. doi: 10.1016/j.jmbbm.2010.12.009. Epub 2010 Dec 24.


Mechanical properties of single bovine trabeculae are unaffected by strain rate.

Szabó ME, Taylor M, Thurner PJ.

J Biomech. 2011 Mar 15;44(5):962-7. doi: 10.1016/j.jbiomech.2010.12.008. Epub 2011 Feb 17.


Osteopontin deficiency increases bone fragility but preserves bone mass.

Thurner PJ, Chen CG, Ionova-Martin S, Sun L, Harman A, Porter A, Ager JW 3rd, Ritchie RO, Alliston T.

Bone. 2010 Jun;46(6):1564-73. doi: 10.1016/j.bone.2010.02.014. Epub 2010 Feb 18.


Atomic force microscopy and indentation force measurement of bone.

Thurner PJ.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Nov-Dec;1(6):624-49. doi: 10.1002/wnan.56. Review.


A new look at the pathogenesis of asthma.

Holgate ST, Arshad HS, Roberts GC, Howarth PH, Thurner P, Davies DE.

Clin Sci (Lond). 2009 Dec 23;118(7):439-50. doi: 10.1042/CS20090474. Review.


Effect of Ca2+ ions on the adhesion and mechanical properties of adsorbed layers of human osteopontin.

Zappone B, Thurner PJ, Adams J, Fantner GE, Hansma PK.

Biophys J. 2008 Sep 15;95(6):2939-50. doi: 10.1529/biophysj.108.135889. Epub 2008 Jun 27.


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