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Items: 1 to 50 of 449

1.

Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats.

Rehman H, Krishnasamy Y, Haque K, Thurman RG, Lemasters JJ, Schnellmann RG, Zhong Z.

PLoS One. 2013 Jun 3;8(6):e65029. doi: 10.1371/journal.pone.0065029. Print 2014.

2.

Glycine reduces platelet aggregation.

Schemmer P, Zhong Z, Galli U, Wheeler MD, Xiangli L, Bradford BU, Conzelmann LO, Forman D, Boyer J, Thurman RG.

Amino Acids. 2013 Mar;44(3):925-31. doi: 10.1007/s00726-012-1422-8. Epub 2012 Nov 8.

3.

TNFalpha is required for cholestasis-induced liver fibrosis in the mouse.

Gäbele E, Froh M, Arteel GE, Uesugi T, Hellerbrand C, Schölmerich J, Brenner DA, Thurman RG, Rippe RA.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):348-53. doi: 10.1016/j.bbrc.2008.10.155. Epub 2008 Nov 6.

4.

Dietary glycine blunts liver injury after bile duct ligation in rats.

Froh M, Zhong Z, Walbrun P, Lehnert M, Netter S, Wiest R, Conzelmann L, Gabele E, Hellerbrand C, Scholmerich J, Thurman RG.

World J Gastroenterol. 2008 Oct 21;14(39):5996-6003.

5.

Heme oxygenase-1 overexpression increases liver injury after bile duct ligation in rats.

Froh M, Conzelmann L, Walbrun P, Netter S, Wiest R, Wheeler MD, Lehnert M, Uesugi T, Scholmerich J, Thurman RG.

World J Gastroenterol. 2007 Jul 7;13(25):3478-86.

6.

Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols.

Zhong Z, Connor HD, Li X, Mason RP, Forman DT, Lemasters JJ, Thurman RG.

J Pharm Pharmacol. 2006 Nov;58(11):1533-43.

PMID:
17132217
7.

Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols.

Zhong Z, Connor HD, Froh M, Bunzendahl H, Lind H, Lehnert M, Mason RP, Thurman RG, Lemasters JJ.

Gastroenterology. 2005 Aug;129(2):652-64.

PMID:
16083719
8.

CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan-polysaccharide complexes of Gram-positive bacterial cell walls.

Li X, Bradford BU, Dalldorf F, Goyert SM, Stimpson SA, Thurman RG, Makarov SS.

Arthritis Res Ther. 2004;6(3):R273-81. Epub 2004 Apr 27.

9.

Polyphenols from Camellia sinenesis prevent primary graft failure after transplantation of ethanol-induced fatty livers from rats.

Zhong Z, Connor HD, Froh M, Lind H, Bunzendahl H, Mason RP, Thurman RG, Lemasters JJ.

Free Radic Biol Med. 2004 May 15;36(10):1248-58.

PMID:
15110390
10.

[Preparing the donor with glycine improves survival after liver transplantation in the animal model].

Schemmer P, Bunzendahl H, Thurman RG.

Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):589-93. German.

PMID:
14518323
11.

[Proteolysis but not ICAM-1 expression in fatty liver increased in tissue harvesting--role of Kupffer cells].

Frankenberg MV, Forman DT, Frey W, Bunzendahl H, Thurman RG.

Langenbecks Arch Chir Suppl Kongressbd. 1998;115(Suppl I):575-9. German.

PMID:
14518320
12.

Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat.

Lehmann TG, Wheeler MD, Froh M, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA, Thurman RG.

Transplantation. 2003 Jul 15;76(1):28-37.

PMID:
12865782
13.

Polyphenols from Camellia sinenesis attenuate experimental cholestasis-induced liver fibrosis in rats.

Zhong Z, Froh M, Lehnert M, Schoonhoven R, Yang L, Lind H, Lemasters JJ, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2003 Nov;285(5):G1004-13. Epub 2003 Jun 4.

14.

Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide.

Lehnert M, Arteel GE, Smutney OM, Conzelmann LO, Zhong Z, Thurman RG, Lemasters JJ.

Shock. 2003 Apr;19(4):345-51.

PMID:
12688546
15.

Isolation of liver Kupffer cells.

Froh M, Konno A, Thurman RG.

Curr Protoc Toxicol. 2003 Feb;Chapter 14:Unit14.4. doi: 10.1002/0471140856.tx1404s14.

PMID:
23045093
16.

New method of delivering gene-altered Kupffer cells to rat liver: studies in an ischemia-reperfusion model.

Froh M, Wheeler MD, Smutney O, Zhong Z, Bradford BU, Thurman RG.

Gastroenterology. 2003 Jan;124(1):172-83.

PMID:
12512041
17.

Up-regulation of CD14 in liver caused by acute ethanol involves oxidant-dependent AP-1 pathway.

Wheeler MD, Thurman RG.

J Biol Chem. 2003 Mar 7;278(10):8435-41. Epub 2002 Dec 13.

18.

In vivo lipid-derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS.

Sato K, Kadiiska MB, Ghio AJ, Corbett J, Fann YC, Holland SM, Thurman RG, Mason RP.

FASEB J. 2002 Nov;16(13):1713-20.

PMID:
12409313
19.

Glycine blocks the increase in intracellular free Ca2+ due to vasoactive mediators in hepatic parenchymal cells.

Qu W, Ikejima K, Zhong Z, Waalkes MP, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2002 Dec;283(6):G1249-56. Epub 2002 Aug 14.

20.

Impaired Ras membrane association and activation in PPARalpha knockout mice after partial hepatectomy.

Wheeler MD, Smutney OM, Check JF, Rusyn I, Schulte-Hermann R, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2003 Feb;284(2):G302-12. Epub 2002 Oct 16.

21.
22.

Cocoa extract protects against early alcohol-induced liver injury in the rat.

McKim SE, Konno A, Gäbele E, Uesugi T, Froh M, Sies H, Thurman RG, Arteel GE.

Arch Biochem Biophys. 2002 Oct 1;406(1):40-6.

PMID:
12234488
23.

Prevention of hepatic ischemia-reperfusion injury by green tea extract.

Zhong Z, Froh M, Connor HD, Li X, Conzelmann LO, Mason RP, Lemasters JJ, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2002 Oct;283(4):G957-64.

24.

Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes.

Froh M, Thurman RG, Wheeler MD.

Am J Physiol Gastrointest Liver Physiol. 2002 Oct;283(4):G856-63.

25.

Effect of Kupffer cell inactivation on ethanol-induced protein adducts in the liver.

Niemelä O, Parkkila S, Bradford B, Iimuro Y, Pasanen M, Thurman RG.

Free Radic Biol Med. 2002 Aug 1;33(3):350-5.

PMID:
12126756
26.

Green tea extract protects against early alcohol-induced liver injury in rats.

Arteel GE, Uesugi T, Bevan LN, Gäbele E, Wheeler MD, McKim SE, Thurman RG.

Biol Chem. 2002 Mar-Apr;383(3-4):663-70.

PMID:
12033455
27.

Nicotine increases hepatic oxygen uptake in the isolated perfused rat liver by inhibiting glycolysis.

Dewar BJ, Bradford BU, Thurman RG.

J Pharmacol Exp Ther. 2002 Jun;301(3):930-7.

PMID:
12023521
28.

Gene and antisense delivery in alcoholism research.

Israel Y, Crews FT, Thurman RG, Tu GC, Garver E, Ponnappa B, Karahanian E, Rubin R, Hoplight B, Sethna M, Hanes R, Wilkie MB, Wheeler MD.

Alcohol Clin Exp Res. 2002 Apr;26(4):582-5.

PMID:
11981136
29.

Endothelial cells contain a glycine-gated chloride channel.

Yamashina S, Konno A, Wheeler MD, Rusyn I, Rusyn EV, Cox AD, Thurman RG.

Nutr Cancer. 2001;40(2):197-204.

PMID:
11962256
30.

Role of lipopolysaccharide-binding protein in early alcohol-induced liver injury in mice.

Uesugi T, Froh M, Arteel GE, Bradford BU, Wheeler MD, Gäbele E, Isayama F, Thurman RG.

J Immunol. 2002 Mar 15;168(6):2963-9.

31.

Viral gene delivery of superoxide dismutase attenuates experimental cholestasis-induced liver fibrosis in the rat.

Zhong Z, Froh M, Wheeler MD, Smutney O, Lehmann TG, Thurman RG.

Gene Ther. 2002 Feb;9(3):183-91.

32.

Protective effect of glycine on renal injury induced by ischemia-reperfusion in vivo.

Yin M, Zhong Z, Connor HD, Bunzendahl H, Finn WF, Rusyn I, Li X, Raleigh JA, Mason RP, Thurman RG.

Am J Physiol Renal Physiol. 2002 Mar;282(3):F417-23.

33.

Comparison of the effect of adenoviral delivery of three superoxide dismutase genes against hepatic ischemia-reperfusion injury.

Wheeler MD, Katuna M, Smutney OM, Froh M, Dikalova A, Mason RP, Samulski RJ, Thurman RG.

Hum Gene Ther. 2001 Dec 10;12(18):2167-77.

PMID:
11779401
34.

The role of Kupffer cell oxidant production in early ethanol-induced liver disease.

Wheeler MD, Kono H, Yin M, Nakagami M, Uesugi T, Arteel GE, Gäbele E, Rusyn I, Yamashina S, Froh M, Adachi Y, Iimuro Y, Bradford BU, Smutney OM, Connor HD, Mason RP, Goyert SM, Peters JM, Gonzalez FJ, Samulski RJ, Thurman RG.

Free Radic Biol Med. 2001 Dec 15;31(12):1544-9. Review.

PMID:
11744328
35.

Delivery of IkappaB superrepressor gene with adenovirus reduces early alcohol-induced liver injury in rats.

Uesugi T, Froh M, Arteel GE, Bradford BU, Gäbele E, Wheeler MD, Thurman RG.

Hepatology. 2001 Dec;34(6):1149-57.

PMID:
11732004
36.

Cu/Zn-superoxide dismutase gene attenuates ischemia-reperfusion injury in the rat kidney.

Yin M, Wheeler MD, Connor HD, Zhong Z, Bunzendahl H, Dikalova A, Samulski RJ, Schoonhoven R, Mason RP, Swenberg JA, Thurman RG.

J Am Soc Nephrol. 2001 Dec;12(12):2691-700.

37.

Cyclosporin A causes a hypermetabolic state and hypoxia in the liver: prevention by dietary glycine.

Zhong Z, Li X, Yamashina S, von Frankenberg M, Enomoto N, Ikejima K, Kolinsky M, Raleigh JA, Thurman RG.

J Pharmacol Exp Ther. 2001 Dec;299(3):858-65.

PMID:
11714869
38.

Alcohol-induced free radicals in mice: direct toxicants or signaling molecules?

Yin M, Gäbele E, Wheeler MD, Connor H, Bradford BU, Dikalova A, Rusyn I, Mason R, Thurman RG.

Hepatology. 2001 Nov;34(5):935-42.

PMID:
11679964
39.

Long-term alcohol exposure changes sensitivity of rat Kupffer cells to lipopolysaccharide.

Enomoto N, Schemmer P, Ikejima K, Takei Y, Sato N, Brenner DA, Thurman RG.

Alcohol Clin Exp Res. 2001 Sep;25(9):1360-7.

PMID:
11584157
40.

Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channel.

Li X, Bradford BU, Wheeler MD, Stimpson SA, Pink HM, Brodie TA, Schwab JH, Thurman RG.

Infect Immun. 2001 Sep;69(9):5883-91.

41.

Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat.

Wheeler MD, Nakagami M, Bradford BU, Uesugi T, Mason RP, Connor HD, Dikalova A, Kadiiska M, Thurman RG.

J Biol Chem. 2001 Sep 28;276(39):36664-72. Epub 2001 Jul 26.

42.

Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice.

Uesugi T, Froh M, Arteel GE, Bradford BU, Thurman RG.

Hepatology. 2001 Jul;34(1):101-8.

PMID:
11431739
43.

Kupffer cell sensitization by alcohol involves increased permeability to gut-derived endotoxin.

Enomoto N, Ikejima K, Yamashina S, Hirose M, Shimizu H, Kitamura T, Takei Y, Sato And N, Thurman RG.

Alcohol Clin Exp Res. 2001 Jun;25(6 Suppl):51S-4S.

PMID:
11410742
44.

Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine.

Rivera CA, Bradford BU, Hunt KJ, Adachi Y, Schrum LW, Koop DR, Burchardt ER, Rippe RA, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2001 Jul;281(1):G200-7.

45.

ICAM-1 is involved in the mechanism of alcohol-induced liver injury: studies with knockout mice.

Kono H, Uesugi T, Froh M, Rusyn I, Bradford BU, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1289-95.

46.

Development of an animal model of chronic alcohol-induced pancreatitis in the rat.

Kono H, Nakagami M, Rusyn I, Connor HD, Stefanovic B, Brenner DA, Mason RP, Arteel GE, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1178-86.

47.

Activated Kupffer cells cause a hypermetabolic state after gentle in situ manipulation of liver in rats.

Schemmer P, Enomoto N, Bradford BU, Bunzendahl H, Raleigh JA, Lemasters JJ, Thurman RG.

Am J Physiol Gastrointest Liver Physiol. 2001 Jun;280(6):G1076-82.

48.

Autonomic nervous system and gut-derived endotoxin: involvement in activation of Kupffer cells after in situ organ manipulation.

Schemmer P, Enomoto N, Bradford BU, Bunzendahl H, Raleigh JA, Thurman RG.

World J Surg. 2001 Apr;25(4):399-406.

PMID:
11344388
49.

Adenoviral gene delivery can inactivate Kupffer cells: role of oxidants in NF-kappaB activation and cytokine production.

Wheeler MD, Yamashina S, Froh M, Rusyn I, Thurman RG.

J Leukoc Biol. 2001 Apr;69(4):622-30.

PMID:
11310849

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