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Items: 10

1.

Contribution of hydrogen bonds to protein stability.

Pace CN, Fu H, Lee Fryar K, Landua J, Trevino SR, Schell D, Thurlkill RL, Imura S, Scholtz JM, Gajiwala K, Sevcik J, Urbanikova L, Myers JK, Takano K, Hebert EJ, Shirley BA, Grimsley GR.

Protein Sci. 2014 May;23(5):652-61. doi: 10.1002/pro.2449. Epub 2014 Mar 25.

2.

Determining the conformational stability of a protein from urea and thermal unfolding curves.

Grimsley GR, Trevino SR, Thurlkill RL, Scholtz JM.

Curr Protoc Protein Sci. 2013;Chapter 28:Unit28.4. doi: 10.1002/0471140864.ps2804s71.

PMID:
23377851
3.

Hydrogen bonding markedly reduces the pK of buried carboxyl groups in proteins.

Thurlkill RL, Grimsley GR, Scholtz JM, Pace CN.

J Mol Biol. 2006 Sep 22;362(3):594-604. Epub 2006 Jul 29.

PMID:
16934292
4.

pK values of the ionizable groups of proteins.

Thurlkill RL, Grimsley GR, Scholtz JM, Pace CN.

Protein Sci. 2006 May;15(5):1214-8. Epub 2006 Apr 5.

5.

pKa of fentanyl varies with temperature: implications for acid-base management during extremes of body temperature.

Thurlkill RL, Cross DA, Scholtz JM, Pace CN.

J Cardiothorac Vasc Anesth. 2005 Dec;19(6):759-62.

PMID:
16326301
6.

Asp79 makes a large, unfavorable contribution to the stability of RNase Sa.

Trevino SR, Gokulan K, Newsom S, Thurlkill RL, Shaw KL, Mitkevich VA, Makarov AA, Sacchettini JC, Scholtz JM, Pace CN.

J Mol Biol. 2005 Dec 9;354(4):967-78. Epub 2005 Oct 21.

PMID:
16288913
7.

pK values of histidine residues in ribonuclease Sa: effect of salt and net charge.

Huyghues-Despointes BM, Thurlkill RL, Daily MD, Schell D, Briggs JM, Antosiewicz JM, Pace CN, Scholtz JM.

J Mol Biol. 2003 Jan 31;325(5):1093-105.

PMID:
12527310
8.

Charge-charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI=3.5) and a basic variant (pI=10.2).

Laurents DV, Huyghues-Despointes BM, Bruix M, Thurlkill RL, Schell D, Newsom S, Grimsley GR, Shaw KL, TreviƱo S, Rico M, Briggs JM, Antosiewicz JM, Scholtz JM, Pace CN.

J Mol Biol. 2003 Jan 31;325(5):1077-92.

PMID:
12527309
9.

Unexpected presence of defective glpR alleles in various strains of Escherichia coli.

Holtman CK, Thurlkill R, Pettigrew DW.

J Bacteriol. 2001 Feb;183(4):1459-61.

10.

Increasing protein stability by altering long-range coulombic interactions.

Grimsley GR, Shaw KL, Fee LR, Alston RW, Huyghues-Despointes BM, Thurlkill RL, Scholtz JM, Pace CN.

Protein Sci. 1999 Sep;8(9):1843-9.

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