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Items: 36


Relationship Between Venules and Perivascular Spaces in Sporadic Small Vessel Diseases.

Jochems ACC, Blair GW, Stringer MS, Thrippleton MJ, Clancy U, Chappell FM, Brown R, Jaime Garcia D, Hamilton OKL, Morgan AG, Marshall I, Hetherington K, Wiseman S, MacGillivray T, Valdés-Hernández MC, Doubal FN, Wardlaw JM.

Stroke. 2020 Apr 8:STROKEAHA120029163. doi: 10.1161/STROKEAHA.120.029163. [Epub ahead of print]


Impact of preterm birth on brain development and long-term outcome: protocol for a cohort study in Scotland.

Boardman JP, Hall J, Thrippleton MJ, Reynolds RM, Bogaert D, Davidson DJ, Schwarze J, Drake AJ, Chandran S, Bastin ME, Fletcher-Watson S.

BMJ Open. 2020 Mar 4;10(3):e035854. doi: 10.1136/bmjopen-2019-035854.


Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth.

Galdi P, Blesa M, Stoye DQ, Sullivan G, Lamb GJ, Quigley AJ, Thrippleton MJ, Bastin ME, Boardman JP.

Neuroimage Clin. 2020;25:102195. doi: 10.1016/j.nicl.2020.102195. Epub 2020 Jan 23.


Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial.

Blair GW, Appleton JP, Flaherty K, Doubal F, Sprigg N, Dooley R, Richardson C, Hamilton I, Law ZK, Shi Y, Stringer MS, Thrippleton MJ, Boyd J, Shuler K, Bath PM, Wardlaw JM.

EClinicalMedicine. 2019 Apr 24;11:34-43. doi: 10.1016/j.eclinm.2019.04.001. eCollection 2019 May-Jun.


Quantifying blood-brain barrier leakage in small vessel disease: Review and consensus recommendations.

Thrippleton MJ, Backes WH, Sourbron S, Ingrisch M, van Osch MJP, Dichgans M, Fazekas F, Ropele S, Frayne R, van Oostenbrugge RJ, Smith EE, Wardlaw JM.

Alzheimers Dement. 2019 Jun;15(6):840-858. doi: 10.1016/j.jalz.2019.01.013. Epub 2019 Apr 25. Review.


Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration.

Smith EE, Biessels GJ, De Guio F, de Leeuw FE, Duchesne S, Düring M, Frayne R, Ikram MA, Jouvent E, MacIntosh BJ, Thrippleton MJ, Vernooij MW, Adams H, Backes WH, Ballerini L, Black SE, Chen C, Corriveau R, DeCarli C, Greenberg SM, Gurol ME, Ingrisch M, Job D, Lam BYK, Launer LJ, Linn J, McCreary CR, Mok VCT, Pantoni L, Pike GB, Ramirez J, Reijmer YD, Romero JR, Ropele S, Rost NS, Sachdev PS, Scott CJM, Seshadri S, Sharma M, Sourbron S, Steketee RME, Swartz RH, van Oostenbrugge R, van Osch M, van Rooden S, Viswanathan A, Werring D, Dichgans M, Wardlaw JM.

Alzheimers Dement (Amst). 2019 Feb 26;11:191-204. doi: 10.1016/j.dadm.2019.01.002. eCollection 2019 Dec. Review.


MRI Relaxometry for Quantitative Analysis of USPIO Uptake in Cerebral Small Vessel Disease.

Thrippleton MJ, Blair GW, Valdes-Hernandez MC, Glatz A, Semple SIK, Doubal F, Vesey A, Marshall I, Newby DE, Wardlaw JM.

Int J Mol Sci. 2019 Feb 12;20(3). pii: E776. doi: 10.3390/ijms20030776.


Convolutional Neural Networks for Direct Inference of Pharmacokinetic Parameters: Application to Stroke Dynamic Contrast-Enhanced MRI.

Ulas C, Das D, Thrippleton MJ, Valdés Hernández MDC, Armitage PA, Makin SD, Wardlaw JM, Menze BH.

Front Neurol. 2019 Jan 8;9:1147. doi: 10.3389/fneur.2018.01147. eCollection 2018.


MRI measurement of blood-brain barrier leakage: minding the gaps.

Thrippleton MJ.

J Physiol. 2019 Feb;597(3):667-668. doi: 10.1113/JP277425. Epub 2018 Dec 25. No abstract available.


Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow.

Shi Y, Thrippleton MJ, Blair GW, Dickie DA, Marshall I, Hamilton I, Doubal FN, Chappell F, Wardlaw JM.

J Cereb Blood Flow Metab. 2020 Jan;40(1):85-99. doi: 10.1177/0271678X18803956. Epub 2018 Oct 8.


Characterisation of tissue-type metabolic content in secondary progressive multiple sclerosis: a magnetic resonance spectroscopic imaging study.

Marshall I, Thrippleton MJ, Bastin ME, Mollison D, Dickie DA, Chappell FM, Semple SIK, Cooper A, Pavitt S, Giovannoni G, Wheeler-Kingshott CAMG, Solanky BS, Weir CJ, Stallard N, Hawkins C, Sharrack B, Chataway J, Connick P, Chandran S; MS-SMART Trialists.

J Neurol. 2018 Aug;265(8):1795-1802. doi: 10.1007/s00415-018-8903-y. Epub 2018 May 30.


Variance components associated with long-echo-time MR spectroscopic imaging in human brain at 1.5T and 3T.

Thrippleton MJ, Parikh JP, Semple SIK, Harris BA, Andrews PJD, Wardlaw JM, Marshall I.

PLoS One. 2017 Dec 29;12(12):e0189872. doi: 10.1371/journal.pone.0189872. eCollection 2017.


Intracranial pulsatility in patients with cerebral small vessel disease: a systematic review.

Shi Y, Thrippleton MJ, Marshall I, Wardlaw JM.

Clin Sci (Lond). 2018 Jan 16;132(1):157-171. doi: 10.1042/CS20171280. Print 2018 Jan 16.


Cerebrovascular reactivity measurement in cerebral small vessel disease: Rationale and reproducibility of a protocol for MRI acquisition and image processing.

Thrippleton MJ, Shi Y, Blair G, Hamilton I, Waiter G, Schwarzbauer C, Pernet C, Andrews PJ, Marshall I, Doubal F, Wardlaw JM.

Int J Stroke. 2018 Feb;13(2):195-206. doi: 10.1177/1747493017730740. Epub 2017 Sep 21.


Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination.

Blair GW, Appleton JP, Law ZK, Doubal F, Flaherty K, Dooley R, Shuler K, Richardson C, Hamilton I, Shi Y, Stringer M, Boyd J, Thrippleton MJ, Sprigg N, Bath PM, Wardlaw JM.

Int J Stroke. 2018 Jul;13(5):530-538. doi: 10.1177/1747493017731947. Epub 2017 Sep 14.


White matter hyperintensity reduction and outcomes after minor stroke.

Wardlaw JM, Chappell FM, Valdés Hernández MDC, Makin SDJ, Staals J, Shuler K, Thrippleton MJ, Armitage PA, Muñoz-Maniega S, Heye AK, Sakka E, Dennis MS.

Neurology. 2017 Sep 5;89(10):1003-1010. doi: 10.1212/WNL.0000000000004328. Epub 2017 Aug 9.


Advanced Neuroimaging of Cerebral Small Vessel Disease.

Blair GW, Hernandez MV, Thrippleton MJ, Doubal FN, Wardlaw JM.

Curr Treat Options Cardiovasc Med. 2017 Jul;19(7):56. doi: 10.1007/s11936-017-0555-1. Review.


Cerebral blood flow in small vessel disease: A systematic review and meta-analysis.

Shi Y, Thrippleton MJ, Makin SD, Marshall I, Geerlings MI, de Craen AJM, van Buchem MA, Wardlaw JM.

J Cereb Blood Flow Metab. 2016 Oct;36(10):1653-1667. Epub 2016 Aug 5. Review.


Integrity of normal-appearing white matter: Influence of age, visible lesion burden and hypertension in patients with small-vessel disease.

Muñoz Maniega S, Chappell FM, Valdés Hernández MC, Armitage PA, Makin SD, Heye AK, Thrippleton MJ, Sakka E, Shuler K, Dennis MS, Wardlaw JM.

J Cereb Blood Flow Metab. 2017 Feb;37(2):644-656. doi: 10.1177/0271678X16635657. Epub 2016 Jul 21.


Magnetic resonance imaging for assessment of cerebrovascular reactivity in cerebral small vessel disease: A systematic review.

Blair GW, Doubal FN, Thrippleton MJ, Marshall I, Wardlaw JM.

J Cereb Blood Flow Metab. 2016 May;36(5):833-41. doi: 10.1177/0271678X16631756. Epub 2016 Feb 16. Review.


Rationale, design and methodology of the image analysis protocol for studies of patients with cerebral small vessel disease and mild stroke.

Valdés Hernández Mdel C, Armitage PA, Thrippleton MJ, Chappell F, Sandeman E, Muñoz Maniega S, Shuler K, Wardlaw JM.

Brain Behav. 2015 Nov 26;5(12):e00415. doi: 10.1002/brb3.415. eCollection 2015 Dec.


Tracer kinetic modelling for DCE-MRI quantification of subtle blood-brain barrier permeability.

Heye AK, Thrippleton MJ, Armitage PA, Valdés Hernández MDC, Makin SD, Glatz A, Sakka E, Wardlaw JM.

Neuroimage. 2016 Jan 15;125:446-455. doi: 10.1016/j.neuroimage.2015.10.018. Epub 2015 Oct 20.


Blood pressure and sodium: Association with MRI markers in cerebral small vessel disease.

Heye AK, Thrippleton MJ, Chappell FM, Hernández Mdel C, Armitage PA, Makin SD, Maniega SM, Sakka E, Flatman PW, Dennis MS, Wardlaw JM.

J Cereb Blood Flow Metab. 2016 Jan;36(1):264-74.


Solid-state dynamics in the closo-carboranes: a (11)B MAS NMR and molecular dynamics study.

Ahumada H, Kurkiewicz T, Thrippleton MJ, Wimperis S.

J Phys Chem B. 2015 Mar 19;119(11):4309-20. doi: 10.1021/acs.jpcb.5b00043. Epub 2015 Mar 4.


Assessment of blood-brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review.

Heye AK, Culling RD, Valdés Hernández Mdel C, Thrippleton MJ, Wardlaw JM.

Neuroimage Clin. 2014 Sep 10;6:262-74. doi: 10.1016/j.nicl.2014.09.002. eCollection 2014. Review.


Unbiased and efficient estimation of the volume of the fibroid uterus using the Cavalieri method and magnetic resonance imaging.

Thrippleton MJ, Munro KI, McKillop G, Newby DE, Marshall I, Roberts N, Critchley HO.

Reprod Sci. 2015 Jan;22(1):15-22. doi: 10.1177/1933719114553451. Epub 2014 Oct 20.


Proton spectroscopic imaging of brain metabolites in basal ganglia of healthy older adults.

Parikh J, Thrippleton MJ, Murray C, Armitage PA, Harris BA, Andrews PJ, Wardlaw JM, Starr JM, Deary IJ, Marshall I.

MAGMA. 2015 Jun;28(3):251-7. doi: 10.1007/s10334-014-0465-0. Epub 2014 Oct 14.


Quantitative serial MRI of the treated fibroid uterus.

Munro KI, Thrippleton MJ, Williams AR, McKillop G, Walker J, Horne AW, Newby DE, Anderson RA, Semple SI, Marshall I, Lewis SC, Millar RP, Bastin ME, Critchley HO.

PLoS One. 2014 Mar 7;9(3):e89809. doi: 10.1371/journal.pone.0089809. eCollection 2014.


Reliability of MRSI brain temperature mapping at 1.5 and 3 T.

Thrippleton MJ, Parikh J, Harris BA, Hammer SJ, Semple SI, Andrews PJ, Wardlaw JM, Marshall I.

NMR Biomed. 2014 Feb;27(2):183-90. doi: 10.1002/nbm.3050. Epub 2013 Nov 24.


Dual-compensated antisymmetric composite refocusing pulses for NMR.

Odedra S, Thrippleton MJ, Wimperis S.

J Magn Reson. 2012 Dec;225:81-92. doi: 10.1016/j.jmr.2012.10.003. Epub 2012 Oct 17.


Ex vivo water diffusion tensor properties of the fibroid uterus at 7 T and their relation to tissue morphology.

Thrippleton MJ, Bastin ME, Munro KI, Williams AR, Oniscu A, Jansen MA, Merrifield GD, McKillop G, Newby DE, Semple SI, Marshall I, Critchley HO.

J Magn Reson Imaging. 2011 Dec;34(6):1445-51. doi: 10.1002/jmri.22793. Epub 2011 Sep 23.


Satellite transitions acquired in real time by magic angle spinning (STARTMAS): "ultrafast" high-resolution MAS NMR spectroscopy of spin I=3/2 nuclei.

Thrippleton MJ, Ball TJ, Wimperis S.

J Chem Phys. 2008 Jan 21;128(3):034507. doi: 10.1063/1.2813892.


Suppression of strong coupling artefacts in J-spectra.

Thrippleton MJ, Edden RA, Keeler J.

J Magn Reson. 2005 May;174(1):97-109.


Cascaded z-filters for efficient single-scan suppression of zero-quantum coherence.

Cano KE, Thrippleton MJ, Keeler J, Shaka AJ.

J Magn Reson. 2004 Apr;167(2):291-7.


Single-scan longitudinal relaxation measurements in high-resolution NMR spectroscopy.

Loening NM, Thrippleton MJ, Keeler J, Griffin RG.

J Magn Reson. 2003 Oct;164(2):321-8.


Elimination of zero-quantum interference in two-dimensional NMR spectra.

Thrippleton MJ, Keeler J.

Angew Chem Int Ed Engl. 2003 Aug 25;42(33):3938-41. No abstract available.


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