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Items: 28

1.

Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.

Khattar V, Fried J, Xu B, Thottassery JV.

Cancer Chemother Pharmacol. 2015 Feb;75(2):411-20. doi: 10.1007/s00280-014-2666-7. Epub 2014 Dec 28.

PMID:
25544127
2.

Cks1 proteasomal turnover is a predominant mode of regulation in breast cancer cells: role of key tyrosines and lysines.

Khattar V, Thottassery JV.

Int J Oncol. 2015 Jan;46(1):395-406. doi: 10.3892/ijo.2014.2728. Epub 2014 Oct 23.

PMID:
25353373
3.

Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine.

Thottassery JV, Sambandam V, Allan PW, Maddry JA, Maxuitenko YY, Tiwari K, Hollingshead M, Parker WB.

Cancer Chemother Pharmacol. 2014 Aug;74(2):291-302. doi: 10.1007/s00280-014-2503-z. Epub 2014 Jun 8.

4.

Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.

Anderson JC, Duarte CW, Welaya K, Rohrbach TD, Bredel M, Yang ES, Choradia NV, Thottassery JV, Yancey Gillespie G, Bonner JA, Willey CD.

Radiother Oncol. 2014 Jun;111(3):468-74. doi: 10.1016/j.radonc.2014.04.010. Epub 2014 May 8.

5.

Cks1: Structure, Emerging Roles and Implications in Multiple Cancers.

Khattar V, Thottassery JV.

J Cancer Ther. 2013 Oct 1;4(8):1341-1354.

6.

Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia.

Hijiya N, Thomson B, Isakoff MS, Silverman LB, Steinherz PG, Borowitz MJ, Kadota R, Cooper T, Shen V, Dahl G, Thottassery JV, Jeha S, Maloney K, Paul JA, Barry E, Carroll WL, Gaynon PS.

Blood. 2011 Dec 1;118(23):6043-9. doi: 10.1182/blood-2011-08-374710. Epub 2011 Oct 3.

7.

Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells.

Lu W, Liu CC, Thottassery JV, Bu G, Li Y.

Biochemistry. 2010 Jun 8;49(22):4635-43. doi: 10.1021/bi1001486.

8.

High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1.

Westbrook L, Ramanathan HN, Isayeva T, Mittal AR, Qu Z, Johnson MD, Kern FG, Ponnazhagan S, Grubbs CJ, Thottassery JV.

Int J Oncol. 2009 May;34(5):1425-31.

PMID:
19360356
9.

Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors.

Qu Z, Van Ginkel S, Roy AM, Westbrook L, Nasrin M, Maxuitenko Y, Frost AR, Carey D, Wang W, Li R, Grizzle WE, Thottassery JV, Kern FG.

Cancer Res. 2008 Aug 1;68(15):6232-40. doi: 10.1158/0008-5472.CAN-07-5654.

10.

Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells.

Westbrook L, Manuvakhova M, Kern FG, Estes NR 2nd, Ramanathan HN, Thottassery JV.

Cancer Res. 2007 Dec 1;67(23):11393-401.

11.

MEK ablation in MCF-7 cells blocks DNA synthesis induced by serum, but not by estradiol or growth factors.

Estes NR 2nd, Thottassery JV, Westbrook L, Kern FG.

Int J Oncol. 2006 Dec;29(6):1573-80.

PMID:
17088999
13.

Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.

Manuvakhova M, Thottassery JV, Hays S, Qu Z, Rentz SS, Westbrook L, Kern FG.

Oncogene. 2006 Sep 28;25(44):6003-14. Epub 2006 May 8.

PMID:
16682955
15.

Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture.

Sadlonova A, Novak Z, Johnson MR, Bowe DB, Gault SR, Page GP, Thottassery JV, Welch DR, Frost AR.

Breast Cancer Res. 2005;7(1):R46-59. Epub 2004 Nov 8.

17.

Homogeneity and long-term stability of tetracycline-regulated gene expression with low basal activity by using the rtTA2S-M2 transactivator and insulator-flanked reporter vectors.

Qu Z, Thottassery JV, Van Ginkel S, Manuvakhova M, Westbrook L, Roland-Lazenby C, Hays S, Kern FG.

Gene. 2004 Feb 18;327(1):61-73.

PMID:
14960361
18.

Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.

Thummel KE, Brimer C, Yasuda K, Thottassery J, Senn T, Lin Y, Ishizuka H, Kharasch E, Schuetz J, Schuetz E.

Mol Pharmacol. 2001 Dec;60(6):1399-406.

PMID:
11723248
19.

Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo.

Lecureur V, Thottassery JV, Sun D, Schuetz EG, Lahti J, Zambetti GP, Schuetz JD.

Oncogene. 2001 Jan 18;20(3):303-13.

20.

Sp1 and egr-1 have opposing effects on the regulation of the rat Pgp2/mdr1b gene.

Thottassery JV, Sun D, Zambetti GP, Troutman A, Sukhatme VP, Schuetz EG, Schuetz JD.

J Biol Chem. 1999 Jan 29;274(5):3199-206.

21.

p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents.

Thottassery JV, Zambetti GP, Arimori K, Schuetz EG, Schuetz JD.

Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):11037-42.

22.

Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway.

Furuya KN, Thottassery JV, Schuetz EG, Sharif M, Schuetz JD.

J Biol Chem. 1997 Apr 25;272(17):11518-25.

23.

Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.

Schuetz JD, Schuetz EG, Thottassery JV, Guzelian PS, Strom S, Sun D.

Mol Pharmacol. 1996 Jan;49(1):63-72.

PMID:
8569713
24.

Divergent regulation of the class II P-glycoprotein gene in primary cultures of hepatocytes versus H35 hepatoma by glucocorticoids.

Schuetz JD, Silverman JA, Thottassery JV, Furuya KN, Schuetz EG.

Cell Growth Differ. 1995 Oct;6(10):1321-32.

25.

Acetylcholine levels, choline acetyltransferase and acetylcholinesterase molecular forms during thyroxine-induced cardiac hypertrophy.

Nyquist-Battie C, Hagler KE, Windberg L, Thottassery JV.

Neurochem Int. 1993 Feb;22(2):143-51.

PMID:
8439768
26.

Mirex-induced adaptive liver growth in rats subjected to thyroidectomy.

Yarbrough JD, Grimley JM, Thottassery JV.

Hepatology. 1992 May;15(5):923-7.

PMID:
1568733
27.

Regulation of perfluorooctanoic acid--induced peroxisomal enzyme activities and hepatocellular growth by adrenal hormones.

Thottassery J, Winberg L, Youssef J, Cunningham M, Badr M.

Hepatology. 1992 Feb;15(2):316-22.

PMID:
1735536
28.

Regulation of glucocorticoid receptors during adaptive liver growth.

Thottassery JV, Yarbrough JD.

Am J Physiol. 1991 Apr;260(4 Pt 1):G603-9.

PMID:
1673321

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