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Live attenuated pertussis vaccine BPZE1 induces a broad antibody response in humans.

Lin A, Apostolovic D, Jahnmatz M, Liang F, Ols S, Tecleab T, Wu C, van Hage M, Solovay K, Rubin K, Locht C, Thorstensson R, Thalen M, Loré K.

J Clin Invest. 2020 Mar 23. pii: 135020. doi: 10.1172/JCI135020. [Epub ahead of print]


Six-week follow-up after HIV-1 exposure: a position statement from the Public Health Agency of Sweden and the Swedish Reference Group for Antiviral Therapy.

Gaines H, Albert J, Axelsson M, Berglund T, Gisslén M, Sönnerborg A, Blaxhult A, Bogdanovic G, Brytting M, Carlander C, Flamholc L, Follin P, Haggar A, Hagstam P, Johansson M, Navér L, Persson Blom J, Samuelson A, Ström H, Sundqvist M, Svedhem Johansson V, Tegmark Wisell K, Tegnell A, Thorstensson R.

Infect Dis (Lond). 2016 Feb;48(2):93-8. doi: 10.3109/23744235.2015.1089593. Epub 2015 Sep 28. Review.


Pertussis-specific memory B-cell and humoral IgG responses in adolescents after a fifth consecutive dose of acellular pertussis vaccine.

Jahnmatz M, Ljungman M, Netterlid E, Jenmalm MC, Nilsson L, Thorstensson R.

Clin Vaccine Immunol. 2014 Sep;21(9):1301-8. doi: 10.1128/CVI.00280-14. Epub 2014 Jul 9.


B-cell responses after intranasal vaccination with the novel attenuated Bordetella pertussis vaccine strain BPZE1 in a randomized phase I clinical trial.

Jahnmatz M, Amu S, Ljungman M, Wehlin L, Chiodi F, Mielcarek N, Locht C, Thorstensson R.

Vaccine. 2014 Jun 5;32(27):3350-6. doi: 10.1016/j.vaccine.2014.04.048. Epub 2014 Apr 29.


A phase I clinical study of a live attenuated Bordetella pertussis vaccine--BPZE1; a single centre, double-blind, placebo-controlled, dose-escalating study of BPZE1 given intranasally to healthy adult male volunteers.

Thorstensson R, Trollfors B, Al-Tawil N, Jahnmatz M, Bergström J, Ljungman M, Törner A, Wehlin L, Van Broekhoven A, Bosman F, Debrie AS, Mielcarek N, Locht C.

PLoS One. 2014 Jan 8;9(1):e83449. doi: 10.1371/journal.pone.0083449. eCollection 2014.


Relation of activation-induced deaminase (AID) expression with antibody response to A(H1N1)pdm09 vaccination in HIV-1 infected patients.

Cagigi A, Pensieroso S, Ruffin N, Sammicheli S, Thorstensson R, Pan-Hammarström Q, Hejdeman B, Nilsson A, Chiodi F.

Vaccine. 2013 Apr 26;31(18):2231-7. doi: 10.1016/j.vaccine.2013.03.002. Epub 2013 Mar 14.


Optimization of a human IgG B-cell ELISpot assay for the analysis of vaccine-induced B-cell responses.

Jahnmatz M, Kesa G, Netterlid E, Buisman AM, Thorstensson R, Ahlborg N.

J Immunol Methods. 2013 May 31;391(1-2):50-9. doi: 10.1016/j.jim.2013.02.009. Epub 2013 Feb 27.


Pandemic influenza A(H1N1)pdm09 seroprevalence in Sweden before and after the pandemic and the vaccination campaign in 2009.

Mörner A, Bråve A, Kling AM, Kühlmann-Berenzon S, Krook K, Hedenskog M, Silhammar I, Ljungman M, Ortqvist A, Andersson S, Brytting M, Thorstensson R, Linde A.

PLoS One. 2012;7(12):e53511. doi: 10.1371/journal.pone.0053511. Epub 2012 Dec 28.


[The Swedish child vaccination program also reaches the children born abroad. Serologic samples show good protection compared to Swedish-born].

Andersson MA, Hallander H, Ljungman M, Norder H, Brytting M, Thorstensson R, Netterlid E.

Lakartidningen. 2012 Jan 18-24;109(3):94-8. Swedish. No abstract available.


Prime-boost vaccination with rBCG/rAd35 enhances CD8⁺ cytolytic T-cell responses in lesions from Mycobacterium tuberculosis-infected primates.

Rahman S, Magalhaes I, Rahman J, Ahmed RK, Sizemore DR, Scanga CA, Weichold F, Verreck F, Kondova I, Sadoff J, Thorstensson R, Spångberg M, Svensson M, Andersson J, Maeurer M, Brighenti S.

Mol Med. 2012 May 9;18:647-58. doi: 10.2119/molmed.2011.00222.


Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques.

Mörner A, Jansson M, Bunnik EM, Schøller J, Vaughan R, Wang Y, Montefiori DC, Otting N, Bontrop R, Bergmeier LA, Singh M, Wyatt RT, Schuitemaker H, Biberfeld G, Thorstensson R, Lehner T.

J Virol. 2011 Jul;85(13):6442-52. doi: 10.1128/JVI.00129-11. Epub 2011 Apr 13.


Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.

Ozkaya Sahin G, Bowles EJ, Parker J, Uchtenhagen H, Sheik-Khalil E, Taylor S, Pybus OG, Mäkitalo B, Walther-Jallow L, Spångberg M, Thorstensson R, Achour A, Fenyö EM, Stewart-Jones GB, Spetz AL.

PLoS Pathog. 2010 Sep 2;6(9):e1001084. doi: 10.1371/journal.ppat.1001084.


High content cellular immune profiling reveals differences between rhesus monkeys and men.

Magalhaes I, Vudattu NK, Ahmed RK, Kühlmann-Berenzon S, Ngo Y, Sizemore DR, Wehlin L, Weichold F, Andersson J, Skeiky YA, Sadoff J, Gaines H, Thorstensson R, Spångberg M, Maeurer MJ.

Immunology. 2010 Sep;131(1):128-40. doi: 10.1111/j.1365-2567.2010.03284.x. Epub 2010 May 10.


International multicenter study to assess a panel of reference materials for quantification of simian immunodeficiency virus RNA in plasma.

Ham C, Srinivasan P, Thorstensson R, Verschoor E, Fagrouche Z, Sernicola L, Ramos A, Titti F, Almond N, Berry N.

J Clin Microbiol. 2010 Jul;48(7):2582-5. doi: 10.1128/JCM.00082-10. Epub 2010 Apr 28.


Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children.

Pensieroso S, Cagigi A, Palma P, Nilsson A, Capponi C, Freda E, Bernardi S, Thorstensson R, Chiodi F, Rossi P.

Proc Natl Acad Sci U S A. 2009 May 12;106(19):7939-44. doi: 10.1073/pnas.0901702106. Epub 2009 Apr 27.


rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector.

Magalhaes I, Sizemore DR, Ahmed RK, Mueller S, Wehlin L, Scanga C, Weichold F, Schirru G, Pau MG, Goudsmit J, Kühlmann-Berenzon S, Spångberg M, Andersson J, Gaines H, Thorstensson R, Skeiky YA, Sadoff J, Maeurer M.

PLoS One. 2008;3(11):e3790. doi: 10.1371/journal.pone.0003790. Epub 2008 Nov 21.


CTA1-DD adjuvant promotes strong immunity against human immunodeficiency virus type 1 envelope glycoproteins following mucosal immunization.

Sundling C, Schön K, Mörner A, Forsell MNE, Wyatt RT, Thorstensson R, Hedestam GBK, Lycke NY.

J Gen Virol. 2008 Dec;89(Pt 12):2954-2964. doi: 10.1099/vir.0.2008/005470-0.


Human immunodeficiency virus type 1 env trimer immunization of macaques and impact of priming with viral vector or stabilized core protein.

Mörner A, Douagi I, Forsell MN, Sundling C, Dosenovic P, O'Dell S, Dey B, Kwong PD, Voss G, Thorstensson R, Mascola JR, Wyatt RT, Karlsson Hedestam GB.

J Virol. 2009 Jan;83(2):540-51. doi: 10.1128/JVI.01102-08. Epub 2008 Nov 12.


B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

Forsell MN, Dey B, Mörner A, Svehla K, O'dell S, Högerkorp CM, Voss G, Thorstensson R, Shaw GM, Mascola JR, Karlsson Hedestam GB, Wyatt RT.

PLoS Pathog. 2008 Oct 3;4(10):e1000171. doi: 10.1371/journal.ppat.1000171.


CD4-independent use of the CCR5 receptor by sequential primary SIVsm isolates.

Laurén A, Vincic E, Hoshino H, Thorstensson R, Fenyö EM.

Retrovirology. 2007 Jul 23;4:50.


Immunological responses and viral modulatory effects of vaccination with recombinant modified vaccinia virus Ankara (rMVA) expressing structural and regulatory transgenes of simian immunodeficiency virus (SIVmac32H/J5M).

Berry N, Stebbings R, Brown S, Christian P, Thorstensson R, Ahmed RK, Davis L, Ferguson D, D'Arcy N, Elsley W, Hull R, Lines J, Wade-Evans A, Stott J, Almond N.

J Med Primatol. 2007 Apr;36(2):80-94.


Multicenter evaluation of a new 4th generation HIV screening assay Elecsys HIV combi.

Weber B, Orazi B, Raineri A, Thorstensson R, Bürgisser P, Mühlbacher A, Areal C, Eiras A, Villaescusa R, Camacho R, Diogo I, Roth HJ, Zahn I, Bartel J, Bossi V, Piro F, Atamasirikul K, Permpikul P, Webber L, Singh S.

Clin Lab. 2006;52(9-10):463-73.


Reverse transcriptase viral load correlates with RNA in SIV/SHIV-infected macaques.

Corrigan GE, Hansson EO, Mörner A, Berry N, Källander CF, Thorstensson R.

AIDS Res Hum Retroviruses. 2006 Sep;22(9):917-23.


Rapid viral decay in simian immunodeficiency virus-infected macaques receiving quadruple antiretroviral therapy.

Brandin E, Thorstensson R, Bonhoeffer S, Albert J.

J Virol. 2006 Oct;80(19):9861-4.


Changes in seroprevalence to four herpesviruses over 30 years in Swedish children aged 9-12 years.

Svahn A, Berggren J, Parke A, Storsaeter J, Thorstensson R, Linde A.

J Clin Virol. 2006 Oct;37(2):118-23. Epub 2006 Sep 12.


Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection.

Titanji K, De Milito A, Cagigi A, Thorstensson R, Grützmeier S, Atlas A, Hejdeman B, Kroon FP, Lopalco L, Nilsson A, Chiodi F.

Blood. 2006 Sep 1;108(5):1580-7. Epub 2006 Apr 27.


A novel assay for assessment of HIV-specific cytotoxicity by multiparameter flow cytometry.

Godoy-Ramirez K, Mäkitalo B, Thorstensson R, Sandström E, Biberfeld G, Gaines H.

Cytometry A. 2005 Dec;68(2):71-80.


Human immunodeficiency virus (HIV)-2-specific T lymphocyte proliferative responses in HIV-2-infected and in HIV-2-exposed but uninfected individuals in Guinea-Bissau.

Andersson S, Larsen O, Da Silva Z, Linder H, Norrgren H, Dias F, Thorstensson R, Aaby P, Biberfeld G.

Clin Exp Immunol. 2005 Mar;139(3):483-9.


Antigen-specific beta-chemokine production and CD8 T-cell noncytotoxic antiviral activity in HIV-2-infected individuals.

Ahmed RK, Norrgren H, da Silva Z, Blaxhult A, Fredriksson EL, Biberfeld G, Andersson S, Thorstensson R.

Scand J Immunol. 2005 Jan;61(1):63-71.


Innate immunity in experimental SIV infection and vaccination.

Ahmed RK, Biberfeld G, Thorstensson R.

Mol Immunol. 2005 Feb;42(2):251-8. Review.


Ethical issues in research on control of the HIV/AIDS epidemic: report from a workshop of the world federation of scientists, Erice, Sicily, Italy, 22-24 August 2003.

de Thé G, Buonaguro F, Charpak N, Franca Junior I, Hutton JL, Thorstensson R, Valdas E, Zetterström R.

Acta Paediatr. 2004 Aug;93(8):1125-8. Erratum in: Acta Paediatr. 2004 Oct;93(10):1407. Franca Junior, I [added].


Enhanced cellular immunity and systemic control of SHIV infection by combined parenteral and mucosal administration of a DNA prime MVA boost vaccine regimen.

Mäkitalo B, Lundholm P, Hinkula J, Nilsson C, Karlén K, Mörner A, Sutter G, Erfle V, Heeney JL, Wahren B, Biberfeld G, Thorstensson R.

J Gen Virol. 2004 Aug;85(Pt 8):2407-2419. doi: 10.1099/vir.0.79869-0.


MhcDRB-sequences from cynomolgus macaques (Macaca fascicularis) of different origin.

Leuchte N, Berry N, Köhler B, Almond N, LeGrand R, Thorstensson R, Titti F, Sauermann U.

Tissue Antigens. 2004 Jun;63(6):529-37.


A simple semi-rapid HIV-1&2 confirmatory immunoassay using magnetic particles.

Sommerfelt MA, Ohlsson I, Flolid I, Thorstensson R, Sørensen B.

J Virol Methods. 2004 Feb;115(2):191-8.


Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection.

De Milito A, Nilsson A, Titanji K, Thorstensson R, Reizenstein E, Narita M, Grutzmeier S, Sönnerborg A, Chiodi F.

Blood. 2004 Mar 15;103(6):2180-6. Epub 2003 Nov 6.


Evolution of coreceptor use and CD4-independence in envelope clones derived from SIVsm-infected macaques.

Vödrös D, Thorstensson R, Doms RW, Fenyö EM, Reeves JD.

Virology. 2003 Nov 10;316(1):17-28.


ELISpot and ELISA analysis of spontaneous, mitogen-induced and antigen-specific cytokine production in cynomolgus and rhesus macaques.

Mäkitalo B, Andersson M, Areström I, Karlén K, Villinger F, Ansari A, Paulie S, Thorstensson R, Ahlborg N.

J Immunol Methods. 2002 Dec 1;270(1):85-97.


Detection of human herpesvirus 8 DNA in serum from blood donors with HHV-8 antibodies indicates possible bloodborne virus transmission.

Enbom M, Urassa W, Massambu C, Thorstensson R, Mhalu F, Linde A.

J Med Virol. 2002 Oct;68(2):264-7.


Strategies for diagnosis of HTLV-I and -II.

Thorstensson R, Albert J, Andersson S.

Transfusion. 2002 Jun;42(6):780-91.


Multicenter evaluation of a new automated fourth-generation human immunodeficiency virus screening assay with a sensitive antigen detection module and high specificity.

Weber B, Gürtler L, Thorstensson R, Michl U, Mühlbacher A, Bürgisser P, Villaescusa R, Eiras A, Gabriel C, Stekel H, Tanprasert S, Oota S, Silvestre MJ, Marques C, Ladeira M, Rabenau H, Berger A, Schmitt U, Melchior W.

J Clin Microbiol. 2002 Jun;40(6):1938-46.


Immunization with recombinant modified vaccinia virus Ankara can modify mucosal simian immunodeficiency virus infection and delay disease progression in macaques.

Nilsson C, Sutter G, Walther-Jallow L, Ten Haaft P, Åkerblom L, Heeney J, Erfle V, Böttiger P, Biberfeld G, Thorstensson R.

J Gen Virol. 2002 Apr;83(Pt 4):807-818. doi: 10.1099/0022-1317-83-4-807.


Coreceptor usage of sequential isolates from cynomolgus monkeys experimentally Infected with simian immunodeficiency virus (SIVsm).

Vödrös D, Thorstensson R, Biberfeld G, Schols D, De Clercq E, Fenyö EM.

Virology. 2001 Dec 5;291(1):12-21.


Cross-protection against mucosal simian immunodeficiency virus (SIVsm) challenge in human immunodeficiency virus type 2-vaccinated cynomolgus monkeys.

Walther-Jallow L, Nilsson C, Söderlund J, Ten Haaft P, Mäkitalo B, Biberfeld P, Böttiger P, Heeney J, Biberfeld G, Thorstensson R.

J Gen Virol. 2001 Jul;82(Pt 7):1601-1612. doi: 10.1099/0022-1317-82-7-1601.


Enhanced simian immunodeficiency virus-specific immune responses in macaques induced by priming with recombinant Semliki Forest virus and boosting with modified vaccinia virus Ankara.

Nilsson C, Mäkitalo B, Berglund P, Bex F, Liljeström P, Sutter G, Erfle V, ten Haaft P, Heeney J, Biberfeld G, Thorstensson R.

Vaccine. 2001 May 14;19(25-26):3526-36.


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