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Homeostatic controllers compensating for growth and perturbations.

Ruoff P, Agafonov O, Tveit DM, Thorsen K, Drengstig T.

PLoS One. 2019 Aug 12;14(8):e0207831. doi: 10.1371/journal.pone.0207831. eCollection 2019.


Coping with transitions in life: a four-year longitudinal narrative study of single younger people with dementia.

Johannessen A, Engedal K, Haugen PK, Dourado MC, Thorsen K.

J Multidiscip Healthc. 2019 Jun 28;12:479-492. doi: 10.2147/JMDH.S208424. eCollection 2019.


Aging With a Physical Disability, Duration of Disability, and Life Satisfaction: A 5-Year Longitudinal Study Among People Aged 40 to 79 Years.

Nicolaisen M, Strand BH, Thorsen K.

Int J Aging Hum Dev. 2019 Jun 25:91415019857061. doi: 10.1177/0091415019857061. [Epub ahead of print] No abstract available.


"We feel included": education and inclusion of health care staff with minority language in elder care.

Krohne K, Døble B, Johannessen A, Thorsen K.

J Multidiscip Healthc. 2018 Dec 20;12:9-19. doi: 10.2147/JMDH.S178458. eCollection 2019.


Developing dementia: The existential experience of the quality of life with young-onset dementia - A longitudinal case study.

Thorsen K, Dourado MCN, Johannessen A.

Dementia (London). 2018 Jul 30:1471301218789990. doi: 10.1177/1471301218789990. [Epub ahead of print]


"To be, or not to be": experiencing deterioration among people with young-onset dementia living alone.

Johannessen A, Engedal K, Haugen PK, Dourado MCN, Thorsen K.

Int J Qual Stud Health Well-being. 2018 Dec;13(1):1490620. doi: 10.1080/17482631.2018.1490620.


Genetic analysis of Charcot-Marie-Tooth disease in Denmark and the implementation of a next generation sequencing platform.

Vaeth S, Christensen R, Dunø M, Lildballe DL, Thorsen K, Vissing J, Svenstrup K, Hertz JM, Andersen H, Jensen UB.

Eur J Med Genet. 2019 Jan;62(1):1-8. doi: 10.1016/j.ejmg.2018.04.003. Epub 2018 Apr 11.


A Rare Case of Embryonal Carcinoma in a Patient with Turner Syndrome without Y Chromosomal Material but Mutations in KIT, AKT1, and ZNF358 Demonstrated Using Exome Sequencing.

Gravholt CH, Dollerup OL, Duval L, Mejlgaard E, Stribolt K, Vang S, Laursen BE, Knudsen M, Thorsen K, Hersmus R, Looijenga LHJ, Stochholm K.

Sex Dev. 2017;11(5-6):262-268. doi: 10.1159/000484398. Epub 2017 Dec 2.


Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome.

Thorsen K, Dam VS, Kjaer-Sorensen K, Pedersen LN, Skeberdis VA, Jurevičius J, Treinys R, Petersen IMBS, Nielsen MS, Oxvig C, Morth JP, Matchkov VV, Aalkjær C, Bundgaard H, Jensen HK.

Nat Commun. 2017 Nov 22;8(1):1696. doi: 10.1038/s41467-017-01630-0.


Variable setpoint as a relaxing component in physiological control.

Risvoll GB, Thorsen K, Ruoff P, Drengstig T.

Physiol Rep. 2017 Sep;5(17). pii: e13408. doi: 10.14814/phy2.13408.


Benefits and burdens: family caregivers' experiences of assistive technology (AT) in everyday life with persons with young-onset dementia (YOD).

Holthe T, Jentoft R, Arntzen C, Thorsen K.

Disabil Rehabil Assist Technol. 2018 Nov;13(8):754-762. doi: 10.1080/17483107.2017.1373151. Epub 2017 Sep 11.


Performance of Homeostatic Controller Motifs Dealing with Perturbations of Rapid Growth and Depletion.

Fjeld G, Thorsen K, Drengstig T, Ruoff P.

J Phys Chem B. 2017 Jun 29;121(25):6097-6107. doi: 10.1021/acs.jpcb.7b01989. Epub 2017 Jun 15.


Mastery and Depressive Symptoms: How Does Mastery Influence the Impact of Stressors From Midlife to Old Age?

Nicolaisen M, Moum T, Thorsen K.

J Aging Health. 2018 Aug;30(7):1084-1107. doi: 10.1177/0898264317705782. Epub 2017 Apr 20.


Enrichment of Genetic Variants in the Glucocorticoid Receptor Signalling Pathway in Autoimmune Hepatitis with Failure of Standard Treatment.

Eriksen PL, Kreutzfeldt M, Grønbaek H, Thorsen K, Vang S, Jessen N, Vilstrup H.

Basic Clin Pharmacol Toxicol. 2017 Sep;121(3):189-194. doi: 10.1111/bcpt.12788. Epub 2017 May 18.


Experiences and needs of spouses of persons with young-onset frontotemporal lobe dementia during the progression of the disease.

Johannessen A, Helvik AS, Engedal K, Thorsen K.

Scand J Caring Sci. 2017 Dec;31(4):779-788. doi: 10.1111/scs.12397. Epub 2017 Mar 9.


Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes.

Møller AB, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo MH, Møller N, Jessen N.

Sci Rep. 2017 Mar 2;7:43775. doi: 10.1038/srep43775.


Evaluating the quality of Marfan genotype-phenotype correlations in existing FBN1 databases.

Groth KA, Von Kodolitsch Y, Kutsche K, Gaustadnes M, Thorsen K, Andersen NH, Gravholt CH.

Genet Med. 2017 Jul;19(7):772-777. doi: 10.1038/gim.2016.181. Epub 2016 Dec 1.


Family Carers of People with Young-Onset Dementia: Their Experiences with the Supporter Service.

Johannessen A, Engedal K, Thorsen K.

Geriatrics (Basel). 2016 Nov 5;1(4). pii: E28. doi: 10.3390/geriatrics1040028.


Reconstitution of Phospholipase A2-Dependent Golgi Membrane Tubules.

Cluett EB, de Figueiredo P, Bechler ME, Thorsen KD, Brown WJ.

Methods Mol Biol. 2016;1496:75-90. doi: 10.1007/978-1-4939-6463-5_7.


What Are Friends for? Friendships and Loneliness Over the Lifespan-From 18 to 79 Years.

Nicolaisen M, Thorsen K.

Int J Aging Hum Dev. 2017 Jan;84(2):126-158. Epub 2016 Jun 28.


Penta-EF-Hand Protein Peflin Is a Negative Regulator of ER-To-Golgi Transport.

Rayl M, Truitt M, Held A, Sargeant J, Thorsen K, Hay JC.

PLoS One. 2016 Jun 8;11(6):e0157227. doi: 10.1371/journal.pone.0157227. eCollection 2016.


Clinical patterns of presentation and attenuated inflammatory response in octo- and nonagenarians with perforated gastroduodenal ulcers.

Søreide K, Thorsen K, Søreide JA.

Surgery. 2016 Aug;160(2):341-9. doi: 10.1016/j.surg.2016.02.027. Epub 2016 Apr 8.


Coping efforts and resilience among adult children who grew up with a parent with young-onset dementia: a qualitative follow-up study.

Johannessen A, Engedal K, Thorsen K.

Int J Qual Stud Health Well-being. 2016 Apr 8;11:30535. doi: 10.3402/qhw.v11.30535. eCollection 2016.


Differential proteome and cellular adhesion analyses of the probiotic bacterium Lactobacillus acidophilus NCFM grown on raffinose - an emerging prebiotic.

Celebioglu HU, Ejby M, Majumder A, Købler C, Goh YJ, Thorsen K, Schmidt B, O'Flaherty S, Abou Hachem M, Lahtinen SJ, Jacobsen S, Klaenhammer TR, Brix S, Mølhave K, Svensson B.

Proteomics. 2016 May;16(9):1361-75. doi: 10.1002/pmic.201500212. Epub 2016 Apr 13.


The Organization of Controller Motifs Leading to Robust Plant Iron Homeostasis.

Agafonov O, Selstø CH, Thorsen K, Xu XM, Drengstig T, Ruoff P.

PLoS One. 2016 Jan 22;11(1):e0147120. doi: 10.1371/journal.pone.0147120. eCollection 2016.


Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease.

Heebøll S, Kreuzfeldt M, Hamilton-Dutoit S, Kjær Poulsen M, Stødkilde-Jørgensen H, Møller HJ, Jessen N, Thorsen K, Kristina Hellberg Y, Bønløkke Pedersen S, Grønbæk H.

Scand J Gastroenterol. 2016;51(4):456-64. doi: 10.3109/00365521.2015.1107620.


Perforated peptic ulcer.

Søreide K, Thorsen K, Harrison EM, Bingener J, Møller MH, Ohene-Yeboah M, Søreide JA.

Lancet. 2015 Sep 26;386(10000):1288-1298. doi: 10.1016/S0140-6736(15)00276-7. Review.


Adult children of parents with young-onset dementia narrate the experiences of their youth through metaphors.

Johannessen A, Engedal K, Thorsen K.

J Multidiscip Healthc. 2015 May 27;8:245-54. doi: 10.2147/JMDH.S84069. eCollection 2015.


Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice.

Kjær TN, Thorsen K, Jessen N, Stenderup K, Pedersen SB.

PLoS One. 2015 May 12;10(5):e0126599. doi: 10.1371/journal.pone.0126599. eCollection 2015.


Difficulties in diagnosing Marfan syndrome using current FBN1 databases.

Groth KA, Gaustadnes M, Thorsen K, Østergaard JR, Jensen UB, Gravholt CH, Andersen NH.

Genet Med. 2016 Jan;18(1):98-102. doi: 10.1038/gim.2015.32. Epub 2015 Mar 26. Review.


Predicting outcomes in patients with perforated gastroduodenal ulcers: artificial neural network modelling indicates a highly complex disease.

Søreide K, Thorsen K, Søreide JA.

Eur J Trauma Emerg Surg. 2015 Feb;41(1):91-8. doi: 10.1007/s00068-014-0417-4. Epub 2014 Jun 14.


AMPKα is critical for enhancing skeletal muscle fatty acid utilization during in vivo exercise in mice.

Fentz J, Kjøbsted R, Birk JB, Jordy AB, Jeppesen J, Thorsen K, Schjerling P, Kiens B, Jessen N, Viollet B, Wojtaszewski JF.

FASEB J. 2015 May;29(5):1725-38. doi: 10.1096/fj.14-266650. Epub 2015 Jan 21.


Robust concentration and frequency control in oscillatory homeostats.

Thorsen K, Agafonov O, Selstø CH, Jolma IW, Ni XY, Drengstig T, Ruoff P.

PLoS One. 2014 Sep 19;9(9):e107766. doi: 10.1371/journal.pone.0107766. eCollection 2014.


Prolonged erythropoietin treatment does not impact gene expression in human skeletal muscle.

Christensen B, Nellemann B, Thorsen K, Nielsen MM, Pedersen SB, Ornstrup MJ, JØrgensen JO, Jessen N.

Muscle Nerve. 2015 Apr;51(4):554-61. doi: 10.1002/mus.24355. Epub 2015 Feb 25.


Apoptosis-linked gene-2 (ALG-2)/Sec31 interactions regulate endoplasmic reticulum (ER)-to-Golgi transport: a potential effector pathway for luminal calcium.

Helm JR, Bentley M, Thorsen KD, Wang T, Foltz L, Oorschot V, Klumperman J, Hay JC.

J Biol Chem. 2014 Aug 22;289(34):23609-28. doi: 10.1074/jbc.M114.561829. Epub 2014 Jul 8.


Transepithelial glucose transport and Na+/K+ homeostasis in enterocytes: an integrative model.

Thorsen K, Drengstig T, Ruoff P.

Am J Physiol Cell Physiol. 2014 Aug 15;307(4):C320-37. doi: 10.1152/ajpcell.00068.2013. Epub 2014 Jun 4.


Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.

Christensen LL, Holm A, Rantala J, Kallioniemi O, Rasmussen MH, Ostenfeld MS, Dagnaes-Hansen F, Øster B, Schepeler T, Tobiasen H, Thorsen K, Sieber OM, Gibbs P, Lamy P, Hansen TF, Jakobsen A, Riising EM, Helin K, Lubinski J, Hagemann-Madsen R, Laurberg S, Ørntoft TF, Andersen CL.

PLoS One. 2014 Jun 3;9(6):e96767. doi: 10.1371/journal.pone.0096767. eCollection 2014.


Next-generation sequencing of RNA and DNA isolated from paired fresh-frozen and formalin-fixed paraffin-embedded samples of human cancer and normal tissue.

Hedegaard J, Thorsen K, Lund MK, Hein AM, Hamilton-Dutoit SJ, Vang S, Nordentoft I, Birkenkamp-Demtröder K, Kruhøffer M, Hager H, Knudsen B, Andersen CL, Sørensen KD, Pedersen JS, Ørntoft TF, Dyrskjøt L.

PLoS One. 2014 May 30;9(5):e98187. doi: 10.1371/journal.pone.0098187. eCollection 2014.


Mutational context and diverse clonal development in early and late bladder cancer.

Nordentoft I, Lamy P, Birkenkamp-Demtröder K, Shumansky K, Vang S, Hornshøj H, Juul M, Villesen P, Hedegaard J, Roth A, Thorsen K, Høyer S, Borre M, Reinert T, Fristrup N, Dyrskjøt L, Shah S, Pedersen JS, Ørntoft TF.

Cell Rep. 2014 Jun 12;7(5):1649-1663. doi: 10.1016/j.celrep.2014.04.038. Epub 2014 May 15.


Hypermethylation of the GABRE~miR-452~miR-224 promoter in prostate cancer predicts biochemical recurrence after radical prostatectomy.

Kristensen H, Haldrup C, Strand S, Mundbjerg K, Mortensen MM, Thorsen K, Ostenfeld MS, Wild PJ, Arsov C, Goering W, Visakorpi T, Egevad L, Lindberg J, Grönberg H, Høyer S, Borre M, Ørntoft TF, Sørensen KD.

Clin Cancer Res. 2014 Apr 15;20(8):2169-81. doi: 10.1158/1078-0432.CCR-13-2642.


Mnk2 alternative splicing modulates the p38-MAPK pathway and impacts Ras-induced transformation.

Maimon A, Mogilevsky M, Shilo A, Golan-Gerstl R, Obiedat A, Ben-Hur V, Lebenthal-Loinger I, Stein I, Reich R, Beenstock J, Zehorai E, Andersen CL, Thorsen K, Ørntoft TF, Davis RJ, Davidson B, Mu D, Karni R.

Cell Rep. 2014 Apr 24;7(2):501-513. doi: 10.1016/j.celrep.2014.03.041. Epub 2014 Apr 13.


What is the best predictor of mortality in perforated peptic ulcer disease? A population-based, multivariable regression analysis including three clinical scoring systems.

Thorsen K, Søreide JA, Søreide K.

J Gastrointest Surg. 2014 Jul;18(7):1261-8. doi: 10.1007/s11605-014-2485-5. Epub 2014 Mar 8.


Nobody asked me how I felt: experiences of adult children of persons with young-onset dementia.

Barca ML, Thorsen K, Engedal K, Haugen PK, Johannessen A.

Int Psychogeriatr. 2014 Dec;26(12):1935-44. doi: 10.1017/S1041610213002639. Epub 2014 Jan 15.


Quantitative proteomics of fractionated membrane and lumen exosome proteins from isogenic metastatic and nonmetastatic bladder cancer cells reveal differential expression of EMT factors.

Jeppesen DK, Nawrocki A, Jensen SG, Thorsen K, Whitehead B, Howard KA, Dyrskjøt L, Ørntoft TF, Larsen MR, Ostenfeld MS.

Proteomics. 2014 Mar;14(6):699-712. doi: 10.1002/pmic.201300452. Epub 2014 Feb 16. Erratum in: Proteomics. 2014 Nov;14(21-22):2628-9.


Predictors of subjective age in people aged 40-79 years: a five-year follow-up study. The impact of mastery, mental and physical health.

Bergland A, Nicolaisen M, Thorsen K.

Aging Ment Health. 2014 Jul;18(5):653-61. doi: 10.1080/13607863.2013.869545. Epub 2013 Dec 20.


Strategies to improve the outcome of emergency surgery for perforated peptic ulcer.

Søreide K, Thorsen K, Søreide JA.

Br J Surg. 2014 Jan;101(1):e51-64. doi: 10.1002/bjs.9368. Epub 2013 Nov 29. Review.


A life-course perspective on stigma-handling: resilience in persons of restricted growth narrated in life histories.

Schanke AK, Thorsen K.

Disabil Rehabil. 2014;36(17):1464-73. doi: 10.3109/09638288.2013.853842. Epub 2013 Nov 18.


Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells.

Birkenkamp-Demtröder K, Hahn SA, Mansilla F, Thorsen K, Maghnouj A, Christensen R, Øster B, Ørntoft TF.

PLoS One. 2013 Sep 9;8(9):e73593. doi: 10.1371/journal.pone.0073593. eCollection 2013.

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