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Items: 1 to 50 of 193

1.

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study.

Wijeysundera DN, Pearse RM, Shulman MA, Abbott TEF, Torres E, Ambosta A, Croal BL, Granton JT, Thorpe KE, Grocott MPW, Farrington C, Myles PS, Cuthbertson BH; METS study investigators.

Lancet. 2018 Jun 30;391(10140):2631-2640. doi: 10.1016/S0140-6736(18)31131-0.

PMID:
30070222
2.

25-hydroxyvitamin D and health service utilization for asthma in early childhood.

Omand JA, To T, O'Connor DL, Parkin PC, Birken CS, Thorpe KE, Maguire JL.

Pediatr Pulmonol. 2018 Aug;53(8):1018-1026. doi: 10.1002/ppul.24067. Epub 2018 Jun 15.

PMID:
29905403
3.

Antibiotic-Resistant Infections: The Authors Reply.

Thorpe KE, Joski P, Johnston KJ.

Health Aff (Millwood). 2018 Jun;37(6):1015. doi: 10.1377/hlthaff.2018.0551. No abstract available.

PMID:
29863930
4.

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial.

Blumberger DM, Vila-Rodriguez F, Thorpe KE, Feffer K, Noda Y, Giacobbe P, Knyahnytska Y, Kennedy SH, Lam RW, Daskalakis ZJ, Downar J.

Lancet. 2018 Apr 28;391(10131):1683-1692. doi: 10.1016/S0140-6736(18)30295-2. Epub 2018 Apr 26. Erratum in: Lancet. 2018 Jun 23;391(10139):e24.

PMID:
29726344
5.

Evaluation of a decision aid for incidental genomic results, the Genomics ADvISER: protocol for a mixed methods randomised controlled trial.

Shickh S, Clausen M, Mighton C, Casalino S, Joshi E, Glogowski E, Schrader KA, Scheer A, Elser C, Panchal S, Eisen A, Graham T, Aronson M, Semotiuk KM, Winter-Paquette L, Evans M, Lerner-Ellis J, Carroll JC, Hamilton JG, Offit K, Robson M, Thorpe KE, Laupacis A, Bombard Y.

BMJ Open. 2018 Apr 26;8(4):e021876. doi: 10.1136/bmjopen-2018-021876.

6.

Antibiotic-Resistant Infection Treatment Costs Have Doubled Since 2002, Now Exceeding $2 Billion Annually.

Thorpe KE, Joski P, Johnston KJ.

Health Aff (Millwood). 2018 Apr;37(4):662-669. doi: 10.1377/hlthaff.2017.1153. Epub 2018 Mar 21.

PMID:
29561692
7.

Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study.

Jaja BNR, Saposnik G, Lingsma HF, Macdonald E, Thorpe KE, Mamdani M, Steyerberg EW, Molyneux A, Manoel ALO, Schatlo B, Hanggi D, Hasan D, Wong GKC, Etminan N, Fukuda H, Torner J, Schaller KL, Suarez JI, Stienen MN, Vergouwen MDI, Rinkel GJE, Spears J, Cusimano MD, Todd M, Le Roux P, Kirkpatrick P, Pickard J, van den Bergh WM, Murray G, Johnston SC, Yamagata S, Mayer S, Schweizer TA, Macdonald RL; SAHIT collaboration.

BMJ. 2018 Jan 18;360:j5745. doi: 10.1136/bmj.j5745. Erratum in: BMJ. 2018 Sep 26;362:k4079.

8.

Risk of Acute Kidney Injury in Patients Randomized to a Restrictive Versus Liberal Approach to Red Blood Cell Transfusion in Cardiac Surgery: A Substudy Protocol of the Transfusion Requirements in Cardiac Surgery III Noninferiority Trial.

Garg AX, Shehata N, McGuinness S, Whitlock R, Fergusson D, Wald R, Parikh C, Bagshaw SM, Khanykin B, Gregory A, Syed S, Hare GMT, Cuerden MS, Thorpe KE, Hall J, Verma S, Roshanov PS, Sontrop JM, Mazer CD.

Can J Kidney Health Dis. 2018 Jan 3;5:2054358117749532. doi: 10.1177/2054358117749532. eCollection 2018.

9.

Transfusion Requirements in Cardiac Surgery III (TRICS III): Study Design of a Randomized Controlled Trial.

Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD.

J Cardiothorac Vasc Anesth. 2018 Feb;32(1):121-129. doi: 10.1053/j.jvca.2017.10.036. Epub 2017 Nov 3.

PMID:
29273477
10.

Association of Social Service Spending, Environmental Quality, and Health Behaviors on Health Outcomes.

Thorpe KE, Joski P.

Popul Health Manag. 2018 Aug;21(4):291-295. doi: 10.1089/pop.2017.0136. Epub 2017 Nov 15.

PMID:
29140747
11.

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery.

Mazer CD, Whitlock RP, Fergusson DA, Hall J, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, McGuinness S, Royse A, Carrier FM, Young PJ, Villar JC, Grocott HP, Seeberger MD, Fremes S, Lellouche F, Syed S, Byrne K, Bagshaw SM, Hwang NC, Mehta C, Painter TW, Royse C, Verma S, Hare GMT, Cohen A, Thorpe KE, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.

N Engl J Med. 2017 Nov 30;377(22):2133-2144. doi: 10.1056/NEJMoa1711818. Epub 2017 Nov 12.

12.

Prehospital cooling to improve successful targeted temperature management after cardiac arrest: A randomized controlled trial.

Scales DC, Cheskes S, Verbeek PR, Pinto R, Austin D, Brooks SC, Dainty KN, Goncharenko K, Mamdani M, Thorpe KE, Morrison LJ; Strategies for Post-Arrest Care SPARC Network.

Resuscitation. 2017 Dec;121:187-194. doi: 10.1016/j.resuscitation.2017.10.002. Epub 2017 Oct 5.

13.

Improving the Appropriate Use of Transthoracic Echocardiography: The Echo WISELY Trial.

Bhatia RS, Ivers NM, Yin XC, Myers D, Nesbitt GC, Edwards J, Yared K, Wadhera RK, Wu JC, Kithcart AP, Wong BM, Hansen MS, Weinerman AS, Shadowitz S, Elman D, Farkouh ME, Thavendiranathan P, Udell JA, Johri AM, Chow CM, Hall J, Bouck Z, Cohen A, Thorpe KE, Rakowski H, Picard MH, Weiner RB.

J Am Coll Cardiol. 2017 Aug 29;70(9):1135-1144. doi: 10.1016/j.jacc.2017.06.065.

14.

The Dx-AF study: a prospective, multicenter, randomized controlled trial comparing VDD-ICD to VVI-ICD in detecting sub-clinical atrial fibrillation in defibrillator patients.

Shurrab M, Janmohamed A, Sarrazin JF, Ayala-Paredes F, Sturmer M, Williams R, Toal S, Lane C, Thorpe KE, Healey JS, Crystal E.

J Interv Card Electrophysiol. 2017 Oct;50(1):57-63. doi: 10.1007/s10840-017-0276-0. Epub 2017 Jul 27.

PMID:
28752228
15.

Protocol for a randomised controlled trial evaluating the effects of providing essential medicines at no charge: the Carefully seLected and Easily Accessible at No Charge Medicines (CLEAN Meds) trial.

Persaud N, Lee T, Ahmad H, Li W, Taglione MS, Rajakulasingam Y, Umali N, Boozary A, Glazier RH, Gomes T, Hwang SW, Jüni P, Law M, Mamdani MM, Manns B, Martin D, Morgan S, Oh P, Pinto AD, Shah BR, Sullivan FM, Thorpe KE, Tu K, Laupacis A.

BMJ Open. 2017 Jun 12;7(5):e015686. doi: 10.1136/bmjopen-2016-015686.

16.

Axillary versus innominate artery cannulation for antegrade cerebral perfusion in aortic surgery: design of the Aortic Surgery Cerebral Protection Evaluation (ACE) CardioLink-3 randomised trial.

Garg V, Peterson MD, Chu MW, Ouzounian M, MacArthur RG, Bozinovski J, El-Hamamsy I, Victor Chu F, Garg A, Hall J, Thorpe KE, Dhingra N, Teoh H, Marotta TR, Latter DA, Quan A, Mamdani M, Juni P, David Mazer C, Verma S.

BMJ Open. 2017 Jun 10;7(6):e014491. doi: 10.1136/bmjopen-2016-014491.

17.

25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children.

Omand JA, To T, O'Connor DL, Parkin PC, Birken CS, Thorpe KE, Maguire JL.

Public Health Nutr. 2017 Jul;20(10):1816-1824. doi: 10.1017/S1368980017000921. Epub 2017 Jun 5.

PMID:
28578751
18.

Randomised trial of mitral valve repair with leaflet resection versus leaflet preservation on functional mitral stenosis (The CAMRA CardioLink-2 Trial).

Chan V, Chu MWA, Leong-Poi H, Latter DA, Hall J, Thorpe KE, de Varennes BE, Quan A, Tsang W, Dhingra N, Yared K, Teoh H, Chu FV, Chan KL, Mesana TG, Connelly KA, Ruel M, Jüni P, Mazer CD, Verma S.

BMJ Open. 2017 May 30;7(5):e015032. doi: 10.1136/bmjopen-2016-015032.

19.

Vitamin D and Fracture Risk in Early Childhood: A Case-Control Study.

Anderson LN, Heong SW, Chen Y, Thorpe KE, Adeli K, Howard A, Sochett E, Birken CS, Parkin PC, Maguire JL; TARGet Kids Collaboration.

Am J Epidemiol. 2017 Jun 15;185(12):1255-1262. doi: 10.1093/aje/kww204.

20.

Re-Evaluation of Serum Ferritin Cut-Off Values for the Diagnosis of Iron Deficiency in Children Aged 12-36 Months.

Abdullah K, Birken CS, Maguire JL, Fehlings D, Hanley AJ, Thorpe KE, Parkin PC.

J Pediatr. 2017 Sep;188:287-290. doi: 10.1016/j.jpeds.2017.03.028. Epub 2017 Apr 18.

PMID:
28431746
21.

The "DOC" screen: Feasible and valid screening for depression, Obstructive Sleep Apnea (OSA) and cognitive impairment in stroke prevention clinics.

Swartz RH, Cayley ML, Lanctôt KL, Murray BJ, Cohen A, Thorpe KE, Sicard MN, Lien K, Sahlas DJ, Herrmann N.

PLoS One. 2017 Apr 4;12(4):e0174451. doi: 10.1371/journal.pone.0174451. eCollection 2017.

22.

How to construct regression models for observational studies (and how NOT to do it!).

Thorpe KE.

Can J Anaesth. 2017 May;64(5):461-470. doi: 10.1007/s12630-017-0833-0. Epub 2017 Feb 24. No abstract available.

PMID:
28236060
23.

Optimizing Pain and Rehabilitation After Knee Arthroplasty: A Two-Center, Randomized Trial.

Choi S, O'Hare T, Gollish J, Paul JE, Kreder H, Thorpe KE, Katz JD, Mamdani M, Moisiuk P, McCartney CJ.

Anesth Analg. 2016 Nov;123(5):1316-1324.

PMID:
27749351
24.

Termination of persistent atrial fibrillation during pulmonary vein isolation: insight from the MAGIC-AF trial.

Singh SM, d'Avila A, Kim YH, Aryana A, Mangrum JM, Michaud GF, Dukkipati SR, Barrett CD, Heist EK, Parides MK, Thorpe KE, Reddy VY.

Europace. 2017 Oct 1;19(10):1657-1663. doi: 10.1093/europace/euw266.

PMID:
27702847
25.

A Randomized Control Trial Using a Validated Prediction Model for Diagnosing Acute Heart Failure in Undifferentiated Dyspneic Emergency Department Patients-Results of the GASP4Ar Study.

Steinhart BD, Levy P, Vandenberghe H, Moe G, Yan AT, Cohen A, Thorpe KE, McGowan M, Mazer CD.

J Card Fail. 2017 Feb;23(2):145-152. doi: 10.1016/j.cardfail.2016.08.007. Epub 2016 Aug 24.

PMID:
27565045
26.

Potential Cost-Effectiveness of Ambulatory Cardiac Rhythm Monitoring After Cryptogenic Stroke.

Yong JH, Thavorn K, Hoch JS, Mamdani M, Thorpe KE, Dorian P, Sharma M, Laupacis A, Gladstone DJ; EMBRACE Steering Committee.

Stroke. 2016 Sep;47(9):2380-5. doi: 10.1161/STROKEAHA.115.011979. Epub 2016 Jul 28.

27.

Persistent Atrial Fibrillation Ablation in Females: Insight from the MAGIC-AF Trial.

Singh SM, D'Avila A, Aryana A, Kim YH, Mangrum JM, Michaud GF, Dukkipati SR, Heist EK, Barrett CD, Thorpe KE, Reddy VY.

J Cardiovasc Electrophysiol. 2016 Nov;27(11):1259-1263. doi: 10.1111/jce.13051. Epub 2016 Aug 30.

PMID:
27461576
28.

Integrating a Smartphone-Based Self-Management System into Usual Care of Advanced CKD.

Ong SW, Jassal SV, Miller JA, Porter EC, Cafazzo JA, Seto E, Thorpe KE, Logan AG.

Clin J Am Soc Nephrol. 2016 Jun 6;11(6):1054-62. doi: 10.2215/CJN.10681015. Epub 2016 May 12.

29.

Post-stroke depression, obstructive sleep apnea, and cognitive impairment: Rationale for, and barriers to, routine screening.

Swartz RH, Bayley M, Lanctôt KL, Murray BJ, Cayley ML, Lien K, Sicard MN, Thorpe KE, Dowlatshahi D, Mandzia JL, Casaubon LK, Saposnik G, Perez Y, Sahlas DJ, Herrmann N.

Int J Stroke. 2016 Jul;11(5):509-18. doi: 10.1177/1747493016641968. Epub 2016 Apr 12. Review.

PMID:
27073189
30.

Why Clinicians Prognosticate Stroke Patients Poorly: Results from the Clinician Judgment versus Risk Score to Predict Stroke Outcomes Randomized Study.

Persaud N, Thorpe KE, Raptis SR, Saposnik G; Stroke Outcomes Research Working Group (SORCan—www.sorcan.ca).

J Stroke Cerebrovasc Dis. 2016 Jun;25(6):1349-54. doi: 10.1016/j.jstrokecerebrovasdis.2016.01.024. Epub 2016 Mar 14.

PMID:
26987489
31.

Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery.

Wijeysundera DN, Pearse RM, Shulman MA, Abbott TE, Torres E, Croal BL, Granton JT, Thorpe KE, Grocott MP, Farrington C, Myles PS, Cuthbertson BH; METS Study Investigators.

BMJ Open. 2016 Mar 11;6(3):e010359. doi: 10.1136/bmjopen-2015-010359. Erratum in: BMJ Open. 2016;6(4):e010359corr1.

32.

Authors' Reply to Gandjour: "The Role of Chronic Disease, Obesity, and Improved Treatment and Detection in Accounting for the Rise in Healthcare Spending Between 1987 and 2011".

Thorpe KE, Allen L, Joski P.

Appl Health Econ Health Policy. 2016 Apr;14(2):243. doi: 10.1007/s40258-016-0233-6. No abstract available.

PMID:
26914552
33.

Validating a Pragmatic Approach to Cognitive Screening in Stroke Prevention Clinics Using the Montreal Cognitive Assessment.

Swartz RH, Cayley ML, Lanctôt KL, Murray BJ, Smith EE, Sahlas DJ, Herrmann N, Cohen A, Thorpe KE.

Stroke. 2016 Mar;47(3):807-13. doi: 10.1161/STROKEAHA.115.011036. Epub 2016 Jan 28.

PMID:
26903584
34.

The modified stepwise ablation guided by low-dose ibutilide in chronic atrial fibrillation trial (The MAGIC-AF Study).

Singh SM, d'Avila A, Kim YH, Aryana A, Mangrum JM, Michaud GF, Dukkipati SR, Barrett CD, Heist EK, Parides MK, Thorpe KE, Reddy VY.

Eur Heart J. 2016 May 21;37(20):1614-21. doi: 10.1093/eurheartj/ehw003. Epub 2016 Feb 4.

PMID:
26850076
35.

Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial.

Hawkes MT, Conroy AL, Opoka RO, Hermann L, Thorpe KE, McDonald C, Kim H, Higgins S, Namasopo S, John C, Miller C, Liles WC, Kain KC.

Malar J. 2015 Oct 29;14:421. doi: 10.1186/s12936-015-0946-2.

36.

Neuroimaging characteristics of ruptured aneurysm as predictors of outcome after aneurysmal subarachnoid hemorrhage: pooled analyses of the SAHIT cohort.

Jaja BN, Lingsma H, Steyerberg EW, Schweizer TA, Thorpe KE, Macdonald RL;  on behalf of SAHIT investigators.

J Neurosurg. 2016 Jun;124(6):1703-11. doi: 10.3171/2015.4.JNS142753. Epub 2015 Oct 23.

PMID:
26495952
37.

Out-Of-Pocket Prescription Costs Under A Typical Silver Plan Are Twice As High As They Are In The Average Employer Plan.

Thorpe KE, Allen L, Joski P.

Health Aff (Millwood). 2015 Oct;34(10):1695-703. doi: 10.1377/hlthaff.2015.0323.

PMID:
26438746
38.

Risk factors, practice variation and hematological outcomes of children identified with non-anemic iron deficiency following screening in primary care setting.

Abdullah K, Thorpe KE, Maguire JL, Birken CS, Fehlings D, Hanley AJ, Parkin PC.

Paediatr Child Health. 2015 Aug-Sep;20(6):302-6.

39.

Design and methods of the Echo WISELY (Will Inappropriate Scenarios for Echocardiography Lessen SignificantlY) study: An investigator-blinded randomized controlled trial of education and feedback intervention to reduce inappropriate echocardiograms.

Bhatia RS, Ivers N, Yin CX, Myers D, Nesbitt G, Edwards J, Yared K, Wadhera R, Wu JC, Wong B, Hansen M, Weinerman A, Shadowitz S, Johri A, Farkouh M, Thavendiranathan P, Udell JA, Rambihar S, Chow CM, Hall J, Thorpe KE, Rakowski H, Weiner RB.

Am Heart J. 2015 Aug;170(2):202-9. doi: 10.1016/j.ahj.2015.04.022. Epub 2015 May 1.

PMID:
26299215
40.

Using a systematic review in clinical decision making: a pilot parallel, randomized controlled trial.

Perrier L, Persaud N, Thorpe KE, Straus SE.

Implement Sci. 2015 Aug 15;10:118. doi: 10.1186/s13012-015-0303-4.

41.

Thyroid cancer patient perceptions of radioactive iodine treatment choice: Follow-up from a decision-aid randomized trial.

Sawka AM, Straus S, Rodin G, Heus L, Brierley JD, Tsang RW, Rotstein L, Ezzat S, Segal P, Gafni A, Thorpe KE, Goldstein DP.

Cancer. 2015 Oct 15;121(20):3717-26. doi: 10.1002/cncr.29548. Epub 2015 Jul 20.

42.

An internal pilot study for a randomized trial aimed at evaluating the effectiveness of iron interventions in children with non-anemic iron deficiency: the OptEC trial.

Abdullah K, Thorpe KE, Mamak E, Maguire JL, Birken CS, Fehlings D, Hanley AJ, Macarthur C, Zlotkin SH, Parkin PC.

Trials. 2015 Jul 14;16:303. doi: 10.1186/s13063-015-0829-4.

43.

Decision aid on radioactive iodine treatment for early stage papillary thyroid cancer: update to study protocol with follow-up extension.

Sawka AM, Straus S, Rodin G, Thorpe KE, Ezzat S, Gafni A, Goldstein DP.

Trials. 2015 Jul 14;16:302. doi: 10.1186/s13063-015-0819-6.

44.

Common Design and Analysis Issues in Clinical Trials.

Thorpe KE.

J Rheumatol. 2015 Jul;42(7):1075-7. doi: 10.3899/jrheum.150461. No abstract available.

PMID:
26136548
45.

The PRECIS-2 tool: designing trials that are fit for purpose.

Loudon K, Treweek S, Sullivan F, Donnan P, Thorpe KE, Zwarenstein M.

BMJ. 2015 May 8;350:h2147. doi: 10.1136/bmj.h2147. No abstract available.

PMID:
25956159
46.

Optimizing early child development for young children with non-anemic iron deficiency in the primary care practice setting (OptEC): study protocol for a randomized controlled trial.

Abdullah K, Thorpe KE, Mamak E, Maguire JL, Birken CS, Fehlings D, Hanley AJ, Macarthur C, Zlotkin SH, Parkin PC.

Trials. 2015 Apr 2;16:132. doi: 10.1186/s13063-015-0635-z.

47.

The Role of Chronic Disease, Obesity, and Improved Treatment and Detection in Accounting for the Rise in Healthcare Spending Between 1987 and 2011.

Thorpe KE, Allen L, Joski P.

Appl Health Econ Health Policy. 2015 Aug;13(4):381-7. doi: 10.1007/s40258-015-0164-7.

PMID:
25850897
48.

Atrial premature beats predict atrial fibrillation in cryptogenic stroke: results from the EMBRACE trial.

Gladstone DJ, Dorian P, Spring M, Panzov V, Mamdani M, Healey JS, Thorpe KE; EMBRACE Steering Committee and Investigators.

Stroke. 2015 Apr;46(4):936-41. doi: 10.1161/STROKEAHA.115.008714. Epub 2015 Feb 19.

PMID:
25700289
49.

Prognostic value of premorbid hypertension and neurological status in aneurysmal subarachnoid hemorrhage: pooled analyses of individual patient data in the SAHIT repository.

Jaja BN, Lingsma H, Schweizer TA, Thorpe KE, Steyerberg EW, Macdonald RL; SAHIT collaboration.

J Neurosurg. 2015 Mar;122(3):644-52. doi: 10.3171/2014.10.JNS132694. Epub 2015 Jan 2.

PMID:
25554825
50.

Effect of a postdischarge virtual ward on readmission or death for high-risk patients: a randomized clinical trial.

Dhalla IA, O'Brien T, Morra D, Thorpe KE, Wong BM, Mehta R, Frost DW, Abrams H, Ko F, Van Rooyen P, Bell CM, Gruneir A, Lewis GH, Daub S, Anderson GM, Hawker GA, Rochon PA, Laupacis A.

JAMA. 2014 Oct 1;312(13):1305-12. doi: 10.1001/jama.2014.11492.

PMID:
25268437

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