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Adverse drug reactions due to oral antibiotics prescribed in the community setting - England.

Baddour LM, Dayer MJ, Thornhill MH.

Infect Dis (Lond). 2019 Sep 12:1-4. doi: 10.1080/23744235.2019.1663918. [Epub ahead of print]


Measuring the symptomatic, physical, emotional and social impacts of dry mouth: A qualitative study.

Gibson B, Periyakaruppiah K, Thornhill MH, Baker SR, Robinson PG.

Gerodontology. 2019 Jul 26. doi: 10.1111/ger.12433. [Epub ahead of print]


Risk of Adverse Reactions to Oral Antibiotics Prescribed by Dentists.

Thornhill MH, Dayer MJ, Durkin MJ, Lockhart PB, Baddour LM.

J Dent Res. 2019 Sep;98(10):1081-1087. doi: 10.1177/0022034519863645. Epub 2019 Jul 17.


Comparison of Opioid Prescribing by Dentists in the United States and England.

Suda KJ, Durkin MJ, Calip GS, Gellad WF, Kim H, Lockhart PB, Rowan SA, Thornhill MH.

JAMA Netw Open. 2019 May 3;2(5):e194303. doi: 10.1001/jamanetworkopen.2019.4303.


Development of a cytology-based multivariate analytical risk index for oral cancer.

Abram TJ, Floriano PN, James R, Kerr AR, Thornhill MH, Redding SW, Vigneswaran N, Raja R, McRae MP, McDevitt JT.

Oral Oncol. 2019 May;92:6-11. doi: 10.1016/j.oraloncology.2019.02.011. Epub 2019 Mar 13.


Reply: Intravenous Drug Use-Associated Endocarditis Complicating Research of Antibiotic Prophylaxis and Guideline Recommendations.

Thornhill MH, Dayer MJ, Chu VH, O'Gara PT, Baddour LM.

J Am Coll Cardiol. 2019 Mar 5;73(8):985-986. doi: 10.1016/j.jacc.2019.01.001. No abstract available.


Fluoroquinolone use and associated adverse drug events in England.

Baddour LM, Dayer MJ, Thornhill MH.

J Infect. 2019 Mar;78(3):249-259. doi: 10.1016/j.jinf.2018.11.001. Epub 2018 Nov 13. No abstract available.


Antibiotic Prophylaxis and Incidence of Endocarditis Before and After the 2007 AHA Recommendations.

Thornhill MH, Gibson TB, Cutler E, Dayer MJ, Chu VH, Lockhart PB, O'Gara PT, Baddour LM.

J Am Coll Cardiol. 2018 Nov 13;72(20):2443-2454. doi: 10.1016/j.jacc.2018.08.2178. Epub 2018 Nov 5.


Antibiotic prophylaxis: Back from the brink.

Thornhill MH, Chambers JB, Prendergast BD, Dayer M, Cahill TJ, Lockhart PB, Baddour LM.

Br Dent J. 2018 Oct 12;225(7):579-580. doi: 10.1038/sj.bdj.2018.875. No abstract available.


Pre-clinical evaluation of novel mucoadhesive bilayer patches for local delivery of clobetasol-17-propionate to the oral mucosa.

Colley HE, Said Z, Santocildes-Romero ME, Baker SR, D'Apice K, Hansen J, Madsen LS, Thornhill MH, Hatton PV, Murdoch C.

Biomaterials. 2018 Sep;178:134-146. doi: 10.1016/j.biomaterials.2018.06.009. Epub 2018 Jun 14.


Infective Endocarditis After Invasive Medical and Surgical Procedures.

Thornhill MH, Dayer MJ, Cahill TJ.

J Am Coll Cardiol. 2018 Jun 19;71(24):2753-2755. doi: 10.1016/j.jacc.2018.03.533. No abstract available.


Assessment of inappropriate antibiotic prescribing among a large cohort of general dentists in the United States.

Durkin MJ, Feng Q, Warren K, Lockhart PB, Thornhill MH, Munshi KD, Henderson RR, Hsueh K, Fraser VJ; Centers for Disease Control and Prevention Epicenters.

J Am Dent Assoc. 2018 May;149(5):372-381.e1. doi: 10.1016/j.adaj.2017.11.034.


Quantifying infective endocarditis risk in patients with predisposing cardiac conditions.

Thornhill MH, Jones S, Prendergast B, Baddour LM, Chambers JB, Lockhart PB, Dayer MJ.

Eur Heart J. 2018 Feb 14;39(7):586-595. doi: 10.1093/eurheartj/ehx655.


An evaluation of dental antibiotic prescribing practices in the United States.

Durkin MJ, Hsueh K, Sallah YH, Feng Q, Jafarzadeh SR, Munshi KD, Lockhart PB, Thornhill MH, Henderson RR, Fraser VJ; Centers for Disease Control and Prevention Epicenters.

J Am Dent Assoc. 2017 Dec;148(12):878-886.e1. doi: 10.1016/j.adaj.2017.07.019. Epub 2017 Sep 20.


Can Changes in Guidelines on the Use of Antibiotic Prophylaxis Before Invasive Dental Procedures Tell Us Whether Antibiotic Prophylaxis Is Effective in Preventing Infective Endocarditis?

Thornhill MH.

Mayo Clin Proc. 2017 May 10. pii: S0025-6196(17)30289-6. doi: 10.1016/j.mayocp.2017.04.005. [Epub ahead of print] No abstract available.


Effect of cigarette smoking on subgingival bacteria in healthy subjects and patients with chronic periodontitis.

Karasneh JA, Al Habashneh RA, Marzouka NA, Thornhill MH.

BMC Oral Health. 2017 Mar 21;17(1):64. doi: 10.1186/s12903-017-0359-4.


Fabrication of Electrospun Mucoadhesive Membranes for Therapeutic Applications in Oral Medicine.

Santocildes-Romero ME, Hadley L, Clitherow KH, Hansen J, Murdoch C, Colley HE, Thornhill MH, Hatton PV.

ACS Appl Mater Interfaces. 2017 Apr 5;9(13):11557-11567. doi: 10.1021/acsami.7b02337. Epub 2017 Mar 24.


A change in the NICE guidelines on antibiotic prophylaxis: British Heart Valve Society update.

Chambers JB, Thornhill MH, Dyer M, Shanson D.

BJGP Open. 2017 Mar 15;1(1):bjgpopen17X100593. doi: 10.3399/bjgpopen17X100593. No abstract available.


Antibiotic Prophylaxis of Infective Endocarditis.

Thornhill MH, Dayer M, Lockhart PB, Prendergast B.

Curr Infect Dis Rep. 2017 Feb;19(2):9. doi: 10.1007/s11908-017-0564-y. Review.


The Cost-Effectiveness of Antibiotic Prophylaxis for Patients at Risk of Infective Endocarditis.

Franklin M, Wailoo A, Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB, Thornhill MH.

Circulation. 2016 Nov 15;134(20):1568-1578.


A change in the NICE guidelines on antibiotic prophylaxis for dental procedures.

Thornhill MH, Chambers JB, Dayer M, Shanson D.

Br J Gen Pract. 2016 Sep;66(650):460-1. doi: 10.3399/bjgp16X686749. No abstract available.


'Cytology-on-a-chip' based sensors for monitoring of potentially malignant oral lesions.

Abram TJ, Floriano PN, Christodoulides N, James R, Kerr AR, Thornhill MH, Redding SW, Vigneswaran N, Speight PM, Vick J, Murdoch C, Freeman C, Hegarty AM, D'Apice K, Phelan JA, Corby PM, Khouly I, Bouquot J, Demian NM, Weinstock YE, Rowan S, Yeh CK, McGuff HS, Miller FR, Gaur S, Karthikeyan K, Taylor L, Le C, Nguyen M, Talavera H, Raja R, Wong J, McDevitt JT.

Oral Oncol. 2016 Sep;60:103-11. doi: 10.1016/j.oraloncology.2016.07.002. Epub 2016 Jul 20.


A change in the NICE guidelines on antibiotic prophylaxis.

Thornhill MH, Dayer M, Lockhart PB, McGurk M, Shanson D, Prendergast B, Chambers JB.

Br Dent J. 2016 Aug 12;221(3):112-4. doi: 10.1038/sj.bdj.2016.554.


Prophylaxis guidelines: Plea to NICE.

Thornhill MH, Dayer M, Lockhart PB, McGurk M, Shanson D, Prendergast B, Chambers JB, Jones S, Baddour LM.

Br Dent J. 2016 Jul 8;221(1):2-3. doi: 10.1038/sj.bdj.2016.470. No abstract available.


The Effect of Antibiotic Prophylaxis Guidelines on Incidence of Infective Endocarditis.

Thornhill MH, Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB.

Can J Cardiol. 2016 Dec;32(12):1578.e9. doi: 10.1016/j.cjca.2016.02.074. Epub 2016 Mar 4. No abstract available.


Guidelines on prophylaxis to prevent infective endocarditis.

Thornhill MH, Dayer M, Lockhart PB, McGurk M, Shanson D, Prendergast B, Chambers JB.

Br Dent J. 2016 Jan 22;220(2):51-6. doi: 10.1038/sj.bdj.2016.49.


Infective endocarditis and antibiotic prophylaxis - Authors' reply.

Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB, Thornhill MH.

Lancet. 2015 Aug 8;386(9993):531-2. doi: 10.1016/S0140-6736(15)61471-4. No abstract available.


Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials.

Speight PM, Abram TJ, Floriano PN, James R, Vick J, Thornhill MH, Murdoch C, Freeman C, Hegarty AM, D'Apice K, Kerr AR, Phelan J, Corby P, Khouly I, Vigneswaran N, Bouquot J, Demian NM, Weinstock YE, Redding SW, Rowan S, Yeh CK, McGuff HS, Miller FR, McDevitt JT.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Oct;120(4):474-82.e2. doi: 10.1016/j.oooo.2015.05.023. Epub 2015 Jun 17.


NICE and antibiotic prophylaxis to prevent endocarditis.

Thornhill MH, Lockhart PB, Prendergast B, Chambers JB, Shanson D.

Br Dent J. 2015 Jun 12;218(11):619-21. doi: 10.1038/sj.bdj.2015.496. Erratum in: Br Dent J. 2015 Jul 24;219(2):59.


Incidence and nature of adverse reactions to antibiotics used as endocarditis prophylaxis.

Thornhill MH, Dayer MJ, Prendergast B, Baddour LM, Jones S, Lockhart PB.

J Antimicrob Chemother. 2015 Aug;70(8):2382-8. doi: 10.1093/jac/dkv115. Epub 2015 Apr 29.


Incidence of infective endocarditis in England, 2000-13: a secular trend, interrupted time-series analysis.

Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB, Thornhill MH.

Lancet. 2015 Mar 28;385(9974):1219-28. doi: 10.1016/S0140-6736(14)62007-9. Epub 2014 Nov 18.


Use of electrical impedance spectroscopy to detect malignant and potentially malignant oral lesions.

Murdoch C, Brown BH, Hearnden V, Speight PM, D'Apice K, Hegarty AM, Tidy JA, Healey TJ, Highfield PE, Thornhill MH.

Int J Nanomedicine. 2014 Sep 23;9:4521-32. doi: 10.2147/IJN.S64087. eCollection 2014.


Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluation.

Colley HE, Hearnden V, Avila-Olias M, Cecchin D, Canton I, Madsen J, MacNeil S, Warren N, Hu K, McKeating JA, Armes SP, Murdoch C, Thornhill MH, Battaglia G.

Mol Pharm. 2014 Apr 7;11(4):1176-88. doi: 10.1021/mp400610b. Epub 2014 Mar 17.


Association of MMP but not TIMP-1 gene polymorphisms with recurrent aphthous stomatitis.

Karasneh JA, Bani-Hani ME, Alkhateeb AM, Hassan AF, Thornhill MH.

Oral Dis. 2014 Oct;20(7):693-9. doi: 10.1111/odi.12190. Epub 2013 Nov 6.


Association of vitamin D receptor gene polymorphisms with chronic and aggressive periodontitis in Jordanian patients.

Karasneh JA, Ababneh KT, Taha AH, Al-Abbadi MS, Marzouka Na, Jaradat SM, Thornhill MH.

Eur J Oral Sci. 2013 Dec;121(6):551-8. doi: 10.1111/eos.12085. Epub 2013 Sep 19.


Combined mathematical modelling and experimentation to predict polymersome uptake by oral cancer cells.

Sorrell I, Shipley RJ, Hearnden V, Colley HE, Thornhill MH, Murdoch C, Webb SD.

Nanomedicine. 2014 Feb;10(2):339-48. doi: 10.1016/j.nano.2013.08.013. Epub 2013 Sep 10.


Polymersome-mediated intracellular delivery of antibiotics to treat Porphyromonas gingivalis-infected oral epithelial cells.

Wayakanon K, Thornhill MH, Douglas CW, Lewis AL, Warren NJ, Pinnock A, Armes SP, Battaglia G, Murdoch C.

FASEB J. 2013 Nov;27(11):4455-65. doi: 10.1096/fj.12-225219. Epub 2013 Aug 6.


Dental surveillance in the adult congenital heart disease population: the authors' reply.

Thornhill MH, Chambers JB, Dayer M, Prendergast BD, Sandoe J, Westaby S.

Heart. 2013 Nov;99(21):1624-5. doi: 10.1136/heartjnl-2013-304513. Epub 2013 Jul 19. No abstract available.


Differential virulence of Candida glabrata glycosylation mutants.

West L, Lowman DW, Mora-Montes HM, Grubb S, Murdoch C, Thornhill MH, Gow NA, Williams D, Haynes K.

J Biol Chem. 2013 Jul 26;288(30):22006-18. doi: 10.1074/jbc.M113.478743. Epub 2013 May 28.


Tissue-engineered oral mucosa to study radiotherapy-induced oral mucositis.

Colley HE, Eves PC, Pinnock A, Thornhill MH, Murdoch C.

Int J Radiat Biol. 2013 Nov;89(11):907-14. doi: 10.3109/09553002.2013.809171. Epub 2013 Jun 26.


NICE guidance on antibiotic prophylaxis to prevent infective endocarditis: a survey of clinicians' attitudes.

Dayer MJ, Chambers JB, Prendergast B, Sandoe JA, Thornhill MH.

QJM. 2013 Mar;106(3):237-43. doi: 10.1093/qjmed/hcs235. Epub 2013 Jan 3.


Infective endocarditis: the impact of the NICE guidelines for antibiotic prophylaxis.

Thornhill MH.

Dent Update. 2012 Jan-Feb;39(1):6-10, 12.


Tissue-engineered oral mucosa.

Moharamzadeh K, Colley H, Murdoch C, Hearnden V, Chai WL, Brook IM, Thornhill MH, Macneil S.

J Dent Res. 2012 Jul;91(7):642-50. doi: 10.1177/0022034511435702. Epub 2012 Jan 19. Review.


Evaluating the use of optical coherence tomography for the detection of epithelial cancers in vitro.

Smith LE, Hearnden V, Lu Z, Smallwood R, Hunter KD, Matcher SJ, Thornhill MH, Murdoch C, MacNeil S.

J Biomed Opt. 2011 Nov;16(11):116015. doi: 10.1117/1.3652708.


Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma.

Colley HE, Hearnden V, Jones AV, Weinreb PH, Violette SM, Macneil S, Thornhill MH, Murdoch C.

Br J Cancer. 2011 Nov 8;105(10):1582-92. doi: 10.1038/bjc.2011.403. Epub 2011 Oct 11.


A new bio-nanochip sensor aids oral cancer detection.

McDevitt J, Weigum SE, Floriano PN, Christodoulides N, Redding SW, Yeh CK, McGuff S, Vigneswaran N, Thornhill MH, Williams MD.

SPIE Newsroom. 2011 Mar 28. pii: 003547.


Impact of the NICE guideline recommending cessation of antibiotic prophylaxis for prevention of infective endocarditis: before and after study.

Thornhill MH, Dayer MJ, Forde JM, Corey GR, Chu VH, Couper DJ, Lockhart PB.

BMJ. 2011 May 3;342:d2392. doi: 10.1136/bmj.d2392.


Candida albicans adhesin Als3p is dispensable for virulence in the mouse model of disseminated candidiasis.

Cleary IA, Reinhard SM, Miller CL, Murdoch C, Thornhill MH, Lazzell AL, Monteagudo C, Thomas DP, Saville SP.

Microbiology. 2011 Jun;157(Pt 6):1806-15. doi: 10.1099/mic.0.046326-0. Epub 2011 Mar 24.


New developments and opportunities in oral mucosal drug delivery for local and systemic disease.

Hearnden V, Sankar V, Hull K, Juras DV, Greenberg M, Kerr AR, Lockhart PB, Patton LL, Porter S, Thornhill MH.

Adv Drug Deliv Rev. 2012 Jan;64(1):16-28. doi: 10.1016/j.addr.2011.02.008. Epub 2011 Mar 1. Review.


Evaluation of tissue engineered models of the oral mucosa to investigate oral candidiasis.

Yadev NP, Murdoch C, Saville SP, Thornhill MH.

Microb Pathog. 2011 Jun;50(6):278-85. doi: 10.1016/j.micpath.2010.11.009. Epub 2011 Feb 3.

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