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Items: 1 to 50 of 324

1.

SENEBLOC, a long non-coding RNA suppresses senescence via p53-dependent and independent mechanisms.

Xu CL, Sang B, Liu GZ, Li JM, Zhang XD, Liu LX, Thorne RF, Wu M.

Nucleic Acids Res. 2020 Feb 7. pii: gkaa063. doi: 10.1093/nar/gkaa063. [Epub ahead of print]

PMID:
32030426
2.

A review of permanent marking for radiotherapy in the UK.

Townend C, Landeg S, Thorne R, Kirby AM, McNair HA.

Radiography (Lond). 2020 Feb;26(1):9-14. doi: 10.1016/j.radi.2019.08.003. Epub 2019 Sep 19.

PMID:
31902461
3.

The legacy of Malcolm Beverley Segal (1937-2019) on the science and fields concerned with choroid plexus and cerebrospinal fluid physiology.

Chodobski A, Ghersi-Egea JF, Preston-Kennedy J, Redzic Z, Strazielle N, Szmydynger-Chodobska J, Thorne RG.

Fluids Barriers CNS. 2019 Dec 19;16(1):41. doi: 10.1186/s12987-019-0161-6.

4.

Evaluating nuclear translocation of surface receptors: recommendations arising from analysis of CD44.

Thorne RF, Wang Y, Zhang Y, Jing X, Zhang XD, de Bock CE, Oliveira CS.

Histochem Cell Biol. 2020 Feb;153(2):77-87. doi: 10.1007/s00418-019-01835-y. Epub 2019 Dec 13.

PMID:
31834485
5.

TP53, TP53 Target Genes (DRAM, TIGAR), and Autophagy.

Hu W, Chen S, Thorne RF, Wu M.

Adv Exp Med Biol. 2019;1206:127-149. doi: 10.1007/978-981-15-0602-4_6. Review.

PMID:
31776983
6.

LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription.

Yari H, Jin L, Teng L, Wang Y, Wu Y, Liu GZ, Gao W, Liang J, Xi Y, Feng YC, Zhang C, Zhang YY, Tabatabaee H, La T, Yang RH, Wang FH, Yan XG, Farrelly M, Scott R, Liu T, Thorne RF, Guo ST, Zhang XD.

Nat Commun. 2019 Nov 25;10(1):5334. doi: 10.1038/s41467-019-13313-z.

7.

Resolution and dose dependence of radiation damage in biomolecular systems.

Atakisi H, Conger L, Moreau DW, Thorne RE.

IUCrJ. 2019 Sep 18;6(Pt 6):1040-1053. doi: 10.1107/S2052252519008777. eCollection 2019 Nov 1.

8.

Using elemental analyses and multivariate statistics to identify the off-site dispersion from informal e-waste processing.

Mudge SM, Pfaffhuber KA, Fobil JN, Bouman EA, Uggerud HT, Thorne RJ.

Environ Sci Process Impacts. 2019 Dec 11;21(12):2042-2057. doi: 10.1039/c9em00444k.

PMID:
31693034
9.

Solvent flows, conformation changes and lattice reordering in a cold protein crystal.

Moreau DW, Atakisi H, Thorne RE.

Acta Crystallogr D Struct Biol. 2019 Nov 1;75(Pt 11):980-994. doi: 10.1107/S2059798319013822. Epub 2019 Oct 31.

PMID:
31692472
10.

Origin of two-band chorus in the radiation belt of Earth.

Li J, Bortnik J, An X, Li W, Angelopoulos V, Thorne RM, Russell CT, Ni B, Shen X, Kurth WS, Hospodarsky GB, Hartley DP, Funsten HO, Spence HE, Baker DN.

Nat Commun. 2019 Oct 14;10(1):4672. doi: 10.1038/s41467-019-12561-3.

11.

Mass Spectrometric Analysis Identifies AIMP1 and LTA4H as FSCN1-Binding Proteins in Laryngeal Squamous Cell Carcinoma.

Gao W, An C, Xue X, Zheng X, Niu M, Zhang Y, Liu H, Zhang C, Lu Y, Cui J, Zhao Q, Wen S, Thorne RF, Zhang X, Wu Y, Wang B.

Proteomics. 2019 Nov;19(21-22):e1900059. doi: 10.1002/pmic.201900059. Epub 2019 Jul 26.

PMID:
31287215
12.

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L, Crump NT, Thorne R, Lau IJ, Repapi E, Dimou D, Smith AL, Harman JR, Telenius JM, Oudelaar AM, Downes DJ, Vyas P, Hughes JR, Milne TA.

Nat Commun. 2019 Jun 26;10(1):2803. doi: 10.1038/s41467-019-10844-3.

13.

Identification of miR-145-5p-Centered Competing Endogenous RNA Network in Laryngeal Squamous Cell Carcinoma.

Gao W, Zhang Y, Niu M, Bo Y, Li H, Xue X, Lu Y, Zheng X, Tang Y, Cui J, He L, Thorne RF, Wang B, Wu Y.

Proteomics. 2019 Nov;19(21-22):e1900020. doi: 10.1002/pmic.201900020. Epub 2019 Jun 20.

PMID:
31169343
14.

CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress.

Li Q, Wang Y, Wu S, Zhou Z, Ding X, Shi R, Thorne RF, Zhang XD, Hu W, Wu M.

Cell Metab. 2019 Jul 2;30(1):157-173.e7. doi: 10.1016/j.cmet.2019.05.009. Epub 2019 May 30.

PMID:
31155494
15.

Ice formation and solvent nanoconfinement in protein crystals.

Moreau DW, Atakisi H, Thorne RE.

IUCrJ. 2019 Mar 13;6(Pt 3):346-356. doi: 10.1107/S2052252519001878. eCollection 2019 May 1.

16.

Activation of Pyroptotic Cell Death Pathways in Cancer: An Alternative Therapeutic Approach.

Nagarajan K, Soundarapandian K, Thorne RF, Li D, Li D.

Transl Oncol. 2019 Jul;12(7):925-931. doi: 10.1016/j.tranon.2019.04.010. Epub 2019 May 11. Review.

17.

FAT1 cadherin controls neuritogenesis during NTera2 cell differentiation.

Ahmed AF, de Bock CE, Sontag E, Hondermarck H, Lincz LF, Thorne RF.

Biochem Biophys Res Commun. 2019 Jun 30;514(3):625-631. doi: 10.1016/j.bbrc.2019.04.197. Epub 2019 May 7.

PMID:
31076104
18.

TP53LNC-DB, the database of lncRNAs in the p53 signalling network.

Khan MR, Bukhari I, Khan R, Hussain HMJ, Wu M, Thorne RF, Li J, Liu G.

Database (Oxford). 2019 Jan 1;2019. doi: 10.1093/database/bay136.

19.

T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development.

de Bock CE, Down M, Baidya K, Sweron B, Boyd AW, Fiers M, Burns GF, Molloy TJ, Lock RB, Soulier J, Taghon T, Van Vlierberghe P, Cools J, Holst J, Thorne RF.

Haematologica. 2019 May;104(5):e204-e207. doi: 10.3324/haematol.2018.198424. Epub 2018 Dec 4. No abstract available.

20.

Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence.

Sang B, Zhang YY, Guo ST, Kong LF, Cheng Q, Liu GZ, Thorne RF, Zhang XD, Jin L, Wu M.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11661-E11670. doi: 10.1073/pnas.1805950115. Epub 2018 Nov 26.

21.

Promoter Methylation-Regulated miR-145-5p Inhibits Laryngeal Squamous Cell Carcinoma Progression by Targeting FSCN1.

Gao W, Zhang C, Li W, Li H, Sang J, Zhao Q, Bo Y, Luo H, Zheng X, Lu Y, Shi Y, Yang D, Zhang R, Li Z, Cui J, Zhang Y, Niu M, Li J, Wu Z, Guo H, Xiang C, Wang J, Hou J, Zhang L, Thorne RF, Cui Y, Wu Y, Wen S, Wang B.

Mol Ther. 2019 Feb 6;27(2):365-379. doi: 10.1016/j.ymthe.2018.09.018. Epub 2018 Sep 27.

22.

A p53-Responsive miRNA Network Promotes Cancer Cell Quiescence.

La T, Liu GZ, Farrelly M, Cole N, Feng YC, Zhang YY, Sherwin SK, Yari H, Tabatabaee H, Yan XG, Guo ST, Liu T, Thorne RF, Jin L, Zhang XD.

Cancer Res. 2018 Dec 1;78(23):6666-6679. doi: 10.1158/0008-5472.CAN-18-1886. Epub 2018 Oct 9.

23.

Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches.

Kumar NN, Pizzo ME, Nehra G, Wilken-Resman B, Boroumand S, Thorne RG.

Bioconjug Chem. 2018 Dec 19;29(12):3937-3966. doi: 10.1021/acs.bioconjchem.8b00548. Epub 2018 Oct 24. Review.

PMID:
30265523
24.

Translating advice to eat more vegetables into practice: observations from a 12-month weight loss trial.

O'Shea J, Tapsell L, Thorne R, Probst Y.

Eur J Clin Nutr. 2019 May;73(5):801-804. doi: 10.1038/s41430-018-0277-9. Epub 2018 Aug 13.

PMID:
30104729
25.

Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery.

Kumar NN, Lochhead JJ, Pizzo ME, Nehra G, Boroumand S, Greene G, Thorne RG.

J Control Release. 2018 Sep 28;286:467-484. doi: 10.1016/j.jconrel.2018.08.006. Epub 2018 Aug 4.

PMID:
30081144
26.

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Martin D, Degese MS, Vitale-Cross L, Iglesias-Bartolome R, Valera JLC, Wang Z, Feng X, Yeerna H, Vadmal V, Moroishi T, Thorne RF, Zaida M, Siegele B, Cheong SC, Molinolo AA, Samuels Y, Tamayo P, Guan KL, Lippman SM, Lyons JG, Gutkind JS.

Nat Commun. 2018 Jul 9;9(1):2372. doi: 10.1038/s41467-018-04590-1.

27.

The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung.

Gao F, Griffin N, Faulkner S, Rowe CW, Williams L, Roselli S, Thorne RF, Ferdoushi A, Jobling P, Walker MM, Hondermarck H.

Sci Rep. 2018 May 25;8(1):8135. doi: 10.1038/s41598-018-26408-2.

28.

Density and electron density of aqueous cryoprotectant solutions at cryogenic temperatures for optimized cryoprotection and diffraction contrast.

Tyree TJ, Dan R, Thorne RE.

Acta Crystallogr D Struct Biol. 2018 May 1;74(Pt 5):471-479. doi: 10.1107/S2059798318003078. Epub 2018 Apr 27.

29.

ACTN4 regulates the stability of RIPK1 in melanoma.

Zhang YY, Tabataba H, Liu XY, Wang JY, Yan XG, Farrelly M, Jiang CC, Guo ST, Liu T, Kao HY, Thorne RF, Zhang XD, Jin L.

Oncogene. 2018 Jul;37(29):4033-4045. doi: 10.1038/s41388-018-0260-x. Epub 2018 Apr 30.

PMID:
29706658
30.

Strategies for enumeration of circulating microvesicles on a conventional flow cytometer: Counting beads and scatter parameters.

Alkhatatbeh MJ, Enjeti AK, Baqar S, Ekinci EI, Liu D, Thorne RF, Lincz LF.

J Circ Biomark. 2018 Apr 5;7:1849454418766966. doi: 10.1177/1849454418766966. eCollection 2018 Jan-Dec.

31.

Effects of protein-crystal hydration and temperature on side-chain conformational heterogeneity in monoclinic lysozyme crystals.

Atakisi H, Moreau DW, Thorne RE.

Acta Crystallogr D Struct Biol. 2018 Apr 1;74(Pt 4):264-278. doi: 10.1107/S2059798318000207. Epub 2018 Apr 3.

32.

GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability.

Hu WL, Jin L, Xu A, Wang YF, Thorne RF, Zhang XD, Wu M.

Nat Cell Biol. 2018 Apr;20(4):492-502. doi: 10.1038/s41556-018-0066-7. Epub 2018 Mar 28.

PMID:
29593331
33.

Awareness and compliance with pharmacovigilance requirements amongst UK oncology healthcare professionals.

Thorne RJ, Bruggink RJ, Kelly SJ, Payne SJ, Purcell SJ, Montgomery DA.

Ecancermedicalscience. 2018 Feb 8;12:809. doi: 10.3332/ecancer.2018.809. eCollection 2018.

34.

The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic' system?

Abbott NJ, Pizzo ME, Preston JE, Janigro D, Thorne RG.

Acta Neuropathol. 2018 Mar;135(3):387-407. doi: 10.1007/s00401-018-1812-4. Epub 2018 Feb 10. Review.

PMID:
29428972
35.

LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect.

Xiang S, Gu H, Jin L, Thorne RF, Zhang XD, Wu M.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1465-E1474. doi: 10.1073/pnas.1711257115. Epub 2018 Jan 29.

36.

The impact of LHC jet data on the MMHT PDF fit at NNLO.

Harland-Lang LA, Martin AD, Thorne RS.

Eur Phys J C Part Fields. 2018;78(3):248. doi: 10.1140/epjc/s10052-018-5710-7. Epub 2018 Mar 22.

37.

Molecular characterization of perivascular drainage pathways in the murine brain.

Hannocks MJ, Pizzo ME, Huppert J, Deshpande T, Abbott NJ, Thorne RG, Sorokin L.

J Cereb Blood Flow Metab. 2018 Apr;38(4):669-686. doi: 10.1177/0271678X17749689. Epub 2017 Dec 28. Erratum in: J Cereb Blood Flow Metab. 2018 Aug;38(8):1384.

38.

Lifetimes and spatio-temporal response of protein crystals in intense X-ray microbeams.

Warkentin MA, Atakisi H, Hopkins JB, Walko D, Thorne RE.

IUCrJ. 2017 Oct 13;4(Pt 6):785-794. doi: 10.1107/S2052252517013495. eCollection 2017 Nov 1.

39.

Development of Potent, Protease-Resistant Agonists of the Parathyroid Hormone Receptor with Broad β Residue Distribution.

Cheloha RW, Chen B, Kumar NN, Watanabe T, Thorne RG, Li L, Gardella TJ, Gellman SH.

J Med Chem. 2017 Nov 9;60(21):8816-8833. doi: 10.1021/acs.jmedchem.7b00876. Epub 2017 Oct 24.

40.

BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma.

Liu F, Jiang CC, Yan XG, Tseng HY, Wang CY, Zhang YY, Yari H, La T, Farrelly M, Guo ST, Thorne RF, Jin L, Wang Q, Zhang XD.

Oncotarget. 2017 May 9;8(41):69477-69492. doi: 10.18632/oncotarget.17704. eCollection 2017 Sep 19.

41.

Neurotrophin Receptors TrkA, p75NTR, and Sortilin Are Increased and Targetable in Thyroid Cancer.

Faulkner S, Jobling P, Rowe CW, Rodrigues Oliveira SM, Roselli S, Thorne RF, Oldmeadow C, Attia J, Jiang CC, Zhang XD, Walker MM, Hondermarck H.

Am J Pathol. 2018 Jan;188(1):229-241. doi: 10.1016/j.ajpath.2017.09.008. Epub 2017 Oct 14.

42.

Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery.

Pizzo ME, Wolak DJ, Kumar NN, Brunette E, Brunnquell CL, Hannocks MJ, Abbott NJ, Meyerand ME, Sorokin L, Stanimirovic DB, Thorne RG.

J Physiol. 2018 Feb 1;596(3):445-475. doi: 10.1113/JP275105. Epub 2017 Dec 18.

43.

Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress.

Wang JY, Liu GZ, Wilmott JS, La T, Feng YC, Yari H, Yan XG, Thorne RF, Scolyer RA, Zhang XD, Jin L.

Cancer Res. 2017 Nov 15;77(22):6226-6239. doi: 10.1158/0008-5472.CAN-17-1965. Epub 2017 Sep 25.

44.

Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase.

Sen K, Horrell S, Kekilli D, Yong CW, Keal TW, Atakisi H, Moreau DW, Thorne RE, Hough MA, Strange RW.

IUCrJ. 2017 Jun 16;4(Pt 4):495-505. doi: 10.1107/S2052252517007527. eCollection 2017 Jul 1.

45.

Measuring the Densities of Aqueous Glasses at Cryogenic Temperatures.

Shen C, Julius EF, Tyree TJ, Dan R, Moreau DW, Thorne R.

J Vis Exp. 2017 Jun 28;(124). doi: 10.3791/55761.

46.

Effect of interdisciplinary care on weight loss: a randomised controlled trial.

Tapsell LC, Lonergan M, Batterham MJ, Neale EP, Martin A, Thorne R, Deane F, Peoples G.

BMJ Open. 2017 Jul 13;7(7):e014533. doi: 10.1136/bmjopen-2016-014533.

47.

Jupiter's magnetosphere and aurorae observed by the Juno spacecraft during its first polar orbits.

Connerney JEP, Adriani A, Allegrini F, Bagenal F, Bolton SJ, Bonfond B, Cowley SWH, Gerard JC, Gladstone GR, Grodent D, Hospodarsky G, Jorgensen JL, Kurth WS, Levin SM, Mauk B, McComas DJ, Mura A, Paranicas C, Smith EJ, Thorne RM, Valek P, Waite J.

Science. 2017 May 26;356(6340):826-832. doi: 10.1126/science.aam5928.

48.

Jupiter's interior and deep atmosphere: The initial pole-to-pole passes with the Juno spacecraft.

Bolton SJ, Adriani A, Adumitroaie V, Allison M, Anderson J, Atreya S, Bloxham J, Brown S, Connerney JEP, DeJong E, Folkner W, Gautier D, Grassi D, Gulkis S, Guillot T, Hansen C, Hubbard WB, Iess L, Ingersoll A, Janssen M, Jorgensen J, Kaspi Y, Levin SM, Li C, Lunine J, Miguel Y, Mura A, Orton G, Owen T, Ravine M, Smith E, Steffes P, Stone E, Stevenson D, Thorne R, Waite J, Durante D, Ebert RW, Greathouse TK, Hue V, Parisi M, Szalay JR, Wilson R.

Science. 2017 May 26;356(6340):821-825. doi: 10.1126/science.aal2108.

PMID:
28546206
49.

MicroRNA-645 is an oncogenic regulator in colon cancer.

Guo ST, Guo XY, Wang J, Wang CY, Yang RH, Wang FH, Li XY, Hondermarck H, Thorne RF, Wang YF, Jin L, Zhang XD, Jiang CC.

Oncogenesis. 2017 May 15;6(5):e335. doi: 10.1038/oncsis.2017.37.

50.

Using data mining to predict success in a weight loss trial.

Batterham M, Tapsell L, Charlton K, O'Shea J, Thorne R.

J Hum Nutr Diet. 2017 Aug;30(4):471-478. doi: 10.1111/jhn.12448. Epub 2017 Feb 7.

PMID:
28168753

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