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Items: 1 to 50 of 108

1.

EBV Persistence--Introducing the Virus.

Thorley-Lawson DA.

Curr Top Microbiol Immunol. 2015;390(Pt 1):151-209. doi: 10.1007/978-3-319-22822-8_8. Review.

2.

The Epstein-Barr virus encoded BART miRNAs potentiate tumor growth in vivo.

Qiu J, Smith P, Leahy L, Thorley-Lawson DA.

PLoS Pathog. 2015 Jan 15;11(1):e1004561. doi: 10.1371/journal.ppat.1004561. eCollection 2015 Jan.

3.

EBV microRNA BART 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replication in B cells.

Qiu J, Thorley-Lawson DA.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11157-62. doi: 10.1073/pnas.1406136111. Epub 2014 Jul 10.

4.

A multifactorial role for P. falciparum malaria in endemic Burkitt's lymphoma pathogenesis.

Torgbor C, Awuah P, Deitsch K, Kalantari P, Duca KA, Thorley-Lawson DA.

PLoS Pathog. 2014 May 29;10(5):e1004170. doi: 10.1371/journal.ppat.1004170. eCollection 2014 May.

5.

The cycle of EBV infection explains persistence, the sizes of the infected cell populations and which come under CTL regulation.

Hawkins JB, Delgado-Eckert E, Thorley-Lawson DA, Shapiro M.

PLoS Pathog. 2013;9(10):e1003685. doi: 10.1371/journal.ppat.1003685. Epub 2013 Oct 17.

6.

The pathogenesis of Epstein-Barr virus persistent infection.

Thorley-Lawson DA, Hawkins JB, Tracy SI, Shapiro M.

Curr Opin Virol. 2013 Jun;3(3):227-32. doi: 10.1016/j.coviro.2013.04.005. Epub 2013 May 15. Review.

7.

Persistence of Epstein-Barr virus in self-reactive memory B cells.

Tracy SI, Kakalacheva K, L├╝nemann JD, Luzuriaga K, Middeldorp J, Thorley-Lawson DA.

J Virol. 2012 Nov;86(22):12330-40. doi: 10.1128/JVI.01699-12. Epub 2012 Sep 5.

8.

An orthotopic model of metastatic nasopharyngeal carcinoma and its application in elucidating a therapeutic target that inhibits metastasis.

Smith PA, Merritt D, Barr L, Thorley-Lawson DA.

Genes Cancer. 2011 Nov;2(11):1023-33. doi: 10.1177/1947601912440878.

9.

Chemotaxis in densely populated tissue determines germinal center anatomy and cell motility: a new paradigm for the development of complex tissues.

Hawkins JB, Jones MT, Plassmann PE, Thorley-Lawson DA.

PLoS One. 2011;6(12):e27650. doi: 10.1371/journal.pone.0027650. Epub 2011 Dec 1.

10.

A novel persistence associated EBV miRNA expression profile is disrupted in neoplasia.

Qiu J, Cosmopoulos K, Pegtel M, Hopmans E, Murray P, Middeldorp J, Shapiro M, Thorley-Lawson DA.

PLoS Pathog. 2011 Aug;7(8):e1002193. doi: 10.1371/journal.ppat.1002193. Epub 2011 Aug 25.

11.

Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza A virus epitopes.

Clute SC, Naumov YN, Watkin LB, Aslan N, Sullivan JL, Thorley-Lawson DA, Luzuriaga K, Welsh RM, Puzone R, Celada F, Selin LK.

J Immunol. 2010 Dec 1;185(11):6753-64. doi: 10.4049/jimmunol.1000812. Epub 2010 Nov 3.

12.

Functional delivery of viral miRNAs via exosomes.

Pegtel DM, Cosmopoulos K, Thorley-Lawson DA, van Eijndhoven MA, Hopmans ES, Lindenberg JL, de Gruijl TD, W├╝rdinger T, Middeldorp JM.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6328-33. doi: 10.1073/pnas.0914843107. Epub 2010 Mar 18.

13.

Germinal center B cells latently infected with Epstein-Barr virus proliferate extensively but do not increase in number.

Roughan JE, Torgbor C, Thorley-Lawson DA.

J Virol. 2010 Jan;84(2):1158-68. doi: 10.1128/JVI.01780-09. Epub 2009 Nov 4.

14.

The dynamics of EBV shedding implicate a central role for epithelial cells in amplifying viral output.

Hadinoto V, Shapiro M, Sun CC, Thorley-Lawson DA.

PLoS Pathog. 2009 Jul;5(7):e1000496. doi: 10.1371/journal.ppat.1000496. Epub 2009 Jul 3.

15.

The intersection of Epstein-Barr virus with the germinal center.

Roughan JE, Thorley-Lawson DA.

J Virol. 2009 Apr;83(8):3968-76. doi: 10.1128/JVI.02609-08. Epub 2009 Feb 4.

16.

Comprehensive profiling of Epstein-Barr virus microRNAs in nasopharyngeal carcinoma.

Cosmopoulos K, Pegtel M, Hawkins J, Moffett H, Novina C, Middeldorp J, Thorley-Lawson DA.

J Virol. 2009 Mar;83(5):2357-67. doi: 10.1128/JVI.02104-08. Epub 2008 Dec 17.

17.

The curious case of the tumour virus: 50 years of Burkitt's lymphoma.

Thorley-Lawson DA, Allday MJ.

Nat Rev Microbiol. 2008 Dec;6(12):913-24. doi: 10.1038/nrmicro2015. Review. Erratum in: Nat Rev Microbiol. 2009 Feb;7(2):172.

PMID:
19008891
18.

A virtual look at Epstein-Barr virus infection: simulation mechanism.

Shapiro M, Duca KA, Lee K, Delgado-Eckert E, Hawkins J, Jarrah AS, Laubenbacher R, Polys NF, Hadinoto V, Thorley-Lawson DA.

J Theor Biol. 2008 Jun 21;252(4):633-48. doi: 10.1016/j.jtbi.2008.01.032. Epub 2008 Feb 16.

19.

Epstein-Barr virus: a paradigm for persistent infection - for real and in virtual reality.

Thorley-Lawson DA, Duca KA, Shapiro M.

Trends Immunol. 2008 Apr;29(4):195-201. doi: 10.1016/j.it.2008.01.006. Epub 2008 Mar 6. Review.

PMID:
18328785
20.

On the dynamics of acute EBV infection and the pathogenesis of infectious mononucleosis.

Hadinoto V, Shapiro M, Greenough TC, Sullivan JL, Luzuriaga K, Thorley-Lawson DA.

Blood. 2008 Feb 1;111(3):1420-7. Epub 2007 Nov 8.

21.

A virtual look at Epstein-Barr virus infection: biological interpretations.

Duca KA, Shapiro M, Delgado-Eckert E, Hadinoto V, Jarrah AS, Laubenbacher R, Lee K, Luzuriaga K, Polys NF, Thorley-Lawson DA.

PLoS Pathog. 2007 Oct 19;3(10):1388-400.

22.
23.

Influence of EBV on the peripheral blood memory B cell compartment.

Souza TA, Stollar BD, Sullivan JL, Luzuriaga K, Thorley-Lawson DA.

J Immunol. 2007 Sep 1;179(5):3153-60.

24.

Pathogens cooperate in lymphomagenesis.

Thorley-Lawson DA, Duca KA.

Nat Med. 2007 Aug;13(8):906-7. No abstract available.

PMID:
17680002
25.

IFN-alpha-stimulated genes and Epstein-Barr virus gene expression distinguish WHO type II and III nasopharyngeal carcinomas.

Pegtel DM, Subramanian A, Meritt D, Tsai CH, Sheen TS, Golub TR, Thorley-Lawson DA.

Cancer Res. 2007 Jan 15;67(2):474-81.

26.

Peripheral B cells latently infected with Epstein-Barr virus display molecular hallmarks of classical antigen-selected memory B cells.

Souza TA, Stollar BD, Sullivan JL, Luzuriaga K, Thorley-Lawson DA.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18093-8. Epub 2005 Dec 5.

27.

Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasis.

Pegtel DM, Subramanian A, Sheen TS, Tsai CH, Golub TR, Thorley-Lawson DA.

J Virol. 2005 Dec;79(24):15430-42.

28.

EBV the prototypical human tumor virus--just how bad is it?

Thorley-Lawson DA.

J Allergy Clin Immunol. 2005 Aug;116(2):251-61; quiz 262. Review.

PMID:
16083776
29.

EBV and systemic lupus erythematosus: a new perspective.

Gross AJ, Hochberg D, Rand WM, Thorley-Lawson DA.

J Immunol. 2005 Jun 1;174(11):6599-607.

30.
31.
32.

Epstein-Barr virus infection in ex vivo tonsil epithelial cell cultures of asymptomatic carriers.

Pegtel DM, Middeldorp J, Thorley-Lawson DA.

J Virol. 2004 Nov;78(22):12613-24.

33.

Acute infection with Epstein-Barr virus targets and overwhelms the peripheral memory B-cell compartment with resting, latently infected cells.

Hochberg D, Souza T, Catalina M, Sullivan JL, Luzuriaga K, Thorley-Lawson DA.

J Virol. 2004 May;78(10):5194-204.

34.

Persistence of the Epstein-Barr virus and the origins of associated lymphomas.

Thorley-Lawson DA, Gross A.

N Engl J Med. 2004 Mar 25;350(13):1328-37. Review. No abstract available.

PMID:
15044644
35.

Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cells in vivo.

Hochberg D, Middeldorp JM, Catalina M, Sullivan JL, Luzuriaga K, Thorley-Lawson DA.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):239-44. Epub 2003 Dec 19.

36.

The dispersal of mucosal memory B cells: evidence from persistent EBV infection.

Laichalk LL, Hochberg D, Babcock GJ, Freeman RB, Thorley-Lawson DA.

Immunity. 2002 May;16(5):745-54.

37.

Epstein-Barr virus: exploiting the immune system.

Thorley-Lawson DA.

Nat Rev Immunol. 2001 Oct;1(1):75-82. Review.

PMID:
11905817
38.

Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen.

Sutkowski N, Conrad B, Thorley-Lawson DA, Huber BT.

Immunity. 2001 Oct;15(4):579-89.

39.

Detection and discrimination of latent and replicative herpesvirus infection at the single cell level in vivo.

Decker LL, Babcock GJ, Thorley-Lawson DA.

Methods Mol Biol. 2001;174:111-6. No abstract available.

PMID:
11357632
40.

Detection of EBV infection at the single-cell level. Precise quantitation of virus-infected cells in vivo.

Babcock GJ, Miyashita-Lin EM, Thorley-Lawson DA.

Methods Mol Biol. 2001;174:103-10. No abstract available.

PMID:
11357631
42.
43.

EBV persistence involves strict selection of latently infected B cells.

Joseph AM, Babcock GJ, Thorley-Lawson DA.

J Immunol. 2000 Sep 15;165(6):2975-81.

44.

A model for persistent infection with Epstein-Barr virus: the stealth virus of human B cells.

Thorley-Lawson DA, Babcock GJ.

Life Sci. 1999;65(14):1433-53. Review.

PMID:
10530796
45.
46.

EBV persistence in memory B cells in vivo.

Babcock GJ, Decker LL, Volk M, Thorley-Lawson DA.

Immunity. 1998 Sep;9(3):395-404.

47.

CD48 binds to heparan sulfate on the surface of epithelial cells.

Ianelli CJ, DeLellis R, Thorley-Lawson DA.

J Biol Chem. 1998 Sep 4;273(36):23367-75.

48.

A ligand for human CD48 on epithelial cells.

Ianelli CJ, Edson CM, Thorley-Lawson DA.

J Immunol. 1997 Oct 15;159(8):3910-20.

PMID:
9378979
49.

Localization of the major NF-kappaB-activating site and the sole TRAF3 binding site of LMP-1 defines two distinct signaling motifs.

Brodeur SR, Cheng G, Baltimore D, Thorley-Lawson DA.

J Biol Chem. 1997 Aug 8;272(32):19777-84.

50.

Identification of the site of Epstein-Barr virus persistence in vivo as a resting B cell.

Miyashita EM, Yang B, Babcock GJ, Thorley-Lawson DA.

J Virol. 1997 Jul;71(7):4882-91. Erratum in: J Virol 1998 Nov;72(11):9419.

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