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Items: 1 to 50 of 74

1.

Parents' prioritised outcomes for trials investigating treatments for paediatric severe infection: a qualitative synthesis.

Woolfall K, O'Hara C, Deja E, Canter R, Khan I, Mouncey P, Carter A, Jones N, Watkins J, Lyttle MD, Tume L, Agbeko R, Tibby SM, Pappachan J, Thorburn K, Rowan KM, Peters MJ, Inwald D; PERUKI (Paediatric Emergency Research in the UK and Ireland) and PICS (Paediatric Intensive Care Society).

Arch Dis Child. 2019 Jun 7. pii: archdischild-2019-316807. doi: 10.1136/archdischild-2019-316807. [Epub ahead of print]

2.

Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial.

Peters MJ, Woolfall K, Khan I, Deja E, Mouncey PR, Wulff J, Mason A, Agbeko RS, Draper ES, Fenn B, Gould DW, Koelewyn A, Klein N, Mackerness C, Martin S, O'Neill L, Ray S, Ramnarayan P, Tibby S, Thorburn K, Tume L, Watkins J, Wellman P, Harrison DA, Rowan KM; FEVER Investigators on behalf of the Paediatric Intensive Care Society Study Group (PICS-SG).

Crit Care. 2019 Mar 7;23(1):69. doi: 10.1186/s13054-019-2354-4.

3.

Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT.

Peters MJ, Khan I, Woolfall K, Deja E, Mouncey PR, Wulff J, Mason A, Agbeko R, Draper ES, Fenn B, Gould DW, Koelewyn A, Klein N, Mackerness C, Martin S, O'Neill L, Ramnarayan P, Tibby S, Tume L, Watkins J, Thorburn K, Wellman P, Harrison DA, Rowan KM.

Health Technol Assess. 2019 Feb;23(5):1-148. doi: 10.3310/hta23050.

4.

Procalcitonin and Other Common Biomarkers Do Not Reliably Identify Patients at Risk for Bacterial Infection After Congenital Heart Surgery.

D'Souza S, Guhadasan R, Jennings R, Siner S, Paulus S, Thorburn K, Chesters C, Downey C, Baines P, Lane S, Carrol E.

Pediatr Crit Care Med. 2019 Mar;20(3):243-251. doi: 10.1097/PCC.0000000000001826.

PMID:
30575697
5.

Voluntary wheel running reveals sex-specific nociceptive factors in murine experimental autoimmune encephalomyelitis.

Mifflin KA, Yousuf MS, Thorburn KC, Huang J, Pérez-Muñoz ME, Tenorio G, Walter J, Ballanyi K, Drohomyrecky PC, Dunn SE, Kerr BJ.

Pain. 2019 Apr;160(4):870-881. doi: 10.1097/j.pain.0000000000001465.

PMID:
30540622
6.

Non-invasive ventilation for the management of children with bronchiolitis (NOVEMBR): a feasibility study and core outcome set development protocol.

van Miert C, Fernandes RM, Eccleson H, Bedson E, Lane S, Peak M, Thorburn K, Compton V, Woolfall K, Lacy D, Williamson P, McNamara PS.

Trials. 2018 Nov 14;19(1):627. doi: 10.1186/s13063-018-2969-9.

7.

Potential impact of maternal vaccination on life-threatening respiratory syncytial virus infection during infancy.

Scheltema NM, Kavelaars XM, Thorburn K, Hennus MP, van Woensel JB, van der Ent CK, Borghans JAM, Bont LJ, Drylewicz J.

Vaccine. 2018 Jul 25;36(31):4693-4700. doi: 10.1016/j.vaccine.2018.06.021. Epub 2018 Jun 22.

8.

Transaminase levels reflect disease severity in children ventilated for respiratory syncytial virus (RSV) bronchiolitis.

Thorburn K, Fulton C, King C, Ramaneswaran D, Alammar A, McNamara PS.

Sci Rep. 2018 Jan 29;8(1):1803. doi: 10.1038/s41598-018-20292-6.

9.

Global respiratory syncytial virus-associated mortality in young children (RSV GOLD): a retrospective case series.

Scheltema NM, Gentile A, Lucion F, Nokes DJ, Munywoki PK, Madhi SA, Groome MJ, Cohen C, Moyes J, Thorburn K, Thamthitiwat S, Oshitani H, Lupisan SP, Gordon A, Sánchez JF, O'Brien KL; PERCH Study Group, Gessner BD, Sutanto A, Mejias A, Ramilo O, Khuri-Bulos N, Halasa N, de-Paris F, Pires MR, Spaeder MC, Paes BA, Simões EAF, Leung TF, da Costa Oliveira MT, de Freitas Lázaro Emediato CC, Bassat Q, Butt W, Chi H, Aamir UB, Ali A, Lucero MG, Fasce RA, Lopez O, Rath BA, Polack FP, Papenburg J, Roglić S, Ito H, Goka EA, Grobbee DE, Nair H, Bont LJ.

Lancet Glob Health. 2017 Oct;5(10):e984-e991. doi: 10.1016/S2214-109X(17)30344-3. Erratum in: Lancet Glob Health. 2017 Dec;5(12 ):e1190.

10.

Respiratory syncytial virus - more chimera than chimpanzee?

Thorburn K.

Curr Med Res Opin. 2016;32(4):699-701. doi: 10.1185/03007995.2016.1157464. Epub 2016 Mar 2. No abstract available.

PMID:
26906878
11.

Manipulation of Neurotransmitter Levels Has Differential Effects on Formalin-Evoked Nociceptive Behavior in Male and Female Mice.

Mifflin KA, Benson C, Thorburn KC, Baker GB, Kerr BJ.

J Pain. 2016 Apr;17(4):483-98. doi: 10.1016/j.jpain.2015.12.013. Epub 2015 Dec 31.

PMID:
26748043
12.

Facial hypersensitivity and trigeminal pathology in mice with experimental autoimmune encephalomyelitis.

Thorburn KC, Paylor JW, Webber CA, Winship IR, Kerr BJ.

Pain. 2016 Mar;157(3):627-42. doi: 10.1097/j.pain.0000000000000409.

PMID:
26545087
13.

An observational study examining the relationship between respiratory symptoms, airway inflammation and bacteriology in children with severe neurodisability.

Trinick RE, Bunni L, Thorburn K, Hackett AP, Dalzell M, McNamara PS.

PLoS One. 2015 Apr 8;10(4):e0124627. doi: 10.1371/journal.pone.0124627. eCollection 2015.

14.

Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens.

Lees EA, Carrol ED, Gerrard C, Hardiman F, Howel G, Timmis A, Thorburn K, Guiver M, McNamara PS.

BMC Infect Dis. 2014 Jun 19;14:343. doi: 10.1186/1471-2334-14-343.

15.

Broken barriers, biomarkers, and blocking antibodies-endothelial activation in sepsis*: no snowflake in an avalanche ever feels responsible. -Voltaire/François-Marie Arouet (1694-1778).

Thorburn K, Baines PB.

Pediatr Crit Care Med. 2013 Sep;14(7):720-1. doi: 10.1097/PCC.0b013e31829b1ea8. No abstract available.

PMID:
24162958
16.

Long-acting injection formulations of antipsychotics for people with schizophrenia had negative effects on clinical relationships.

Scanlan JN, Thorburn K.

Aust Occup Ther J. 2013 Aug;60(4):305-7. doi: 10.1111/1440-1630.12066. No abstract available.

PMID:
23888982
17.

Heated, humidified high-flow nasal cannula therapy in viral bronchiolitis--Panacea, passing phase, or progress?*.

Thorburn K, Ritson P.

Pediatr Crit Care Med. 2012 Nov;13(6):700-1. doi: 10.1097/PCC.0b013e3182677456. No abstract available.

PMID:
23128595
18.

Pulmonary bacterial coinfection in infants and children with viral respiratory infection.

Thorburn K, Riordan A.

Expert Rev Anti Infect Ther. 2012 Aug;10(8):909-16. doi: 10.1586/eri.12.80. Review.

PMID:
23030330
19.

Clinical course and outcome for critically ill children with Down syndrome: a retrospective cohort study.

Tibby SM, Durward A, Goh CT, Thorburn K, Morris K, Broadhead M, Peters MJ.

Intensive Care Med. 2012 Aug;38(8):1365-71. doi: 10.1007/s00134-012-2589-x. Epub 2012 May 15.

PMID:
22584799
20.

Mortality and morbidity of nosocomial respiratory syncytial virus (RSV) infection in ventilated children--a ten year perspective.

Thorburn K, Eisenhut M, Riordan A.

Minerva Anestesiol. 2012 Jul;78(7):782. Epub 2012 Mar 13.

21.

Catheter-associated bloodstream infections: primum non nocere (firstly, do no harm).

Thorburn K, Darbyshire AP.

Pediatr Crit Care Med. 2012 Mar;13(2):229-30. doi: 10.1097/PCC.0b013e3182191dd8. No abstract available.

PMID:
22391837
22.

Concomitant bacterial pneumonia and empirical antibiotics in severe respiratory syncytial virus infection.

Thorburn K, Shetty N, Darbyshire AP.

Pediatr Crit Care Med. 2011 Jan;12(1):119; author reply 119-20. doi: 10.1097/PCC.0b013e3181fe292f. No abstract available.

PMID:
21209581
23.

Right ventricular function in children with severe respiratory syncytial virus (RSV) bronchiolitis.

Thorburn K, Eisenhut M, Shauq A, Narayanswamy S, Burgess M.

Minerva Anestesiol. 2011 Jan;77(1):46-53. Epub 2010 Nov 24.

24.

Bovine jugular vein valved conduit: up to 10 years follow-up.

Prior N, Alphonso N, Arnold P, Peart I, Thorburn K, Venugopal P, Corno AF.

J Thorac Cardiovasc Surg. 2011 Apr;141(4):983-7. doi: 10.1016/j.jtcvs.2010.08.037. Epub 2010 Sep 29.

25.

Death by acid rain: VAP or EXIT?

Thorburn K, Darbyshire A.

Crit Care. 2009;13(6):1008. doi: 10.1186/cc8169. Epub 2009 Nov 2.

26.

Autopsies in children continue to reveal unanticipated discrepancies between autopsy findings and antemortem clinical diagnoses.

Narayanan A, Thorburn K, Baines P.

Arch Dis Child. 2009 Aug;94(8):645. doi: 10.1136/adc.2008.150417. No abstract available.

PMID:
19628884
27.

Bacterial tracheitis: a multi-centre perspective.

Tebruegge M, Pantazidou A, Thorburn K, Riordan A, Round J, De Munter C, Walters S, Curtis N.

Scand J Infect Dis. 2009;41(8):548-57. doi: 10.1080/00365540902913478. Review.

PMID:
19401934
28.

Histiocytic sarcoma presenting with chylous ascites in a 7-month-old infant: a case report.

El-Matary W, Thorburn K, Baillie C, Kokai G, Dalzell M.

J Pediatr Hematol Oncol. 2009 Jan;31(1):65-8. doi: 10.1097/MPH.0b013e318180bb95.

PMID:
19125093
29.

Antibiotic-resistant bacteria and infection in children with cerebral palsy requiring mechanical ventilation.

Thorburn K, Jardine M, Taylor N, Reilly N, Sarginson RE, van Saene HK.

Pediatr Crit Care Med. 2009 Mar;10(2):222-6. doi: 10.1097/PCC.0b013e31819368ac.

PMID:
19057452
30.

Pre-existing disease is associated with a significantly higher risk of death in severe respiratory syncytial virus infection.

Thorburn K.

Arch Dis Child. 2009 Feb;94(2):99-103. doi: 10.1136/adc.2008.139188. Epub 2008 Jul 24.

PMID:
18653625
32.
33.

Pulmonary bacterial co-infection in children ventilated for severe respiratory syncytial virus bronchiolitis is common.

Thorburn K, Van Saene H.

Intensive Care Med. 2007 Mar;33(3):565. Epub 2006 Dec 20. No abstract available.

PMID:
17177046
34.

Myocardial injury in infants ventilated on the paediatric intensive care unit: a case control study.

Clark SJ, Eisenhut M, Sidaras D, Hancock SW, Newland P, Thorburn K.

Crit Care. 2006;10(5):R128.

35.
36.

High incidence of pulmonary bacterial co-infection in children with severe respiratory syncytial virus (RSV) bronchiolitis.

Thorburn K, Harigopal S, Reddy V, Taylor N, van Saene HK.

Thorax. 2006 Jul;61(7):611-5. Epub 2006 Mar 14.

37.
38.

The influence of hyperchloraemia on acid base interpretation in diabetic ketoacidosis.

Taylor D, Durward A, Tibby SM, Thorburn K, Holton F, Johnstone IC, Murdoch IA.

Intensive Care Med. 2006 Feb;32(2):295-301. doi: 10.1007/s00134-005-0009-1. Epub 2006 Jan 31.

PMID:
16447033
39.

High mortality of invasive pneumococcal disease compared with meningococcal disease in critically ill children.

Thorburn K, Taylor N, Lopez-Rodriguez L, Ashworth M, de la Cal MA, van Saene HK.

Intensive Care Med. 2005 Nov;31(11):1550-7. Epub 2005 Sep 16.

PMID:
16167128
40.
42.

Cardiac Troponin T levels and myocardial involvement in children with severe respiratory syncytial virus lung disease.

Eisenhut M, Sidaras D, Johnson R, Newland P, Thorburn K.

Acta Paediatr. 2004 Jul;93(7):887-90.

PMID:
15303802
43.

RSV outbreak in a paediatric intensive care unit.

Thorburn K, Kerr S, Taylor N, van Saene HK.

J Hosp Infect. 2004 Jul;57(3):194-201.

PMID:
15236847
44.

Transaminase levels in ventilated children with respiratory syncytial virus bronchiolitis.

Eisenhut M, Thorburn K, Ahmed T.

Intensive Care Med. 2004 May;30(5):931-4. Epub 2004 Mar 13.

PMID:
15024569
45.

Effects of feeding on gastric tonometric measurements in critically ill children.

Thorburn K, Durward A, Tibby SM, Murdoch IA.

Crit Care Med. 2004 Jan;32(1):246-9.

PMID:
14707587
46.

Aluminum accumulation in critically ill children on sucralfate therapy.

Thorburn K, Samuel M, Smith EA, Baines P.

Pediatr Crit Care Med. 2001 Jul;2(3):247-249.

PMID:
12793950
47.

Tracheal bronchus associated with VACTERL.

Kairamkonda V, Thorburn K, Sarginson R.

Eur J Pediatr. 2003 Mar;162(3):165-7. Epub 2003 Jan 31.

PMID:
12655420
48.

Comments on: A new prognostic scoring system for meningococcal septic shock in children.

Baines P, Thorburn K.

Intensive Care Med. 2002 Nov;28(11):1670; author reply 1671-2. No abstract available.

PMID:
12583378
49.
50.

Hepatitis associated with severe respiratory syncytial virus-positive lower respiratory tract infection.

Eisenhut M, Thorburn K.

Scand J Infect Dis. 2002;34(3):235. No abstract available.

PMID:
12030407

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