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Items: 8

1.

Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility.

Hughes AR, Spreen WR, Mosteller M, Warren LL, Lai EH, Brothers CH, Cox C, Nelsen AJ, Hughes S, Thorborn DE, Stancil B, Hetherington SV, Burns DK, Roses AD.

Pharmacogenomics J. 2008 Dec;8(6):365-74. doi: 10.1038/tpj.2008.3. Epub 2008 Mar 11. Review.

PMID:
18332899
2.

HLA-B*5701 screening for hypersensitivity to abacavir.

Mallal S, Phillips E, Carosi G, Molina JM, Workman C, Tomazic J, Jägel-Guedes E, Rugina S, Kozyrev O, Cid JF, Hay P, Nolan D, Hughes S, Hughes A, Ryan S, Fitch N, Thorborn D, Benbow A; PREDICT-1 Study Team.

N Engl J Med. 2008 Feb 7;358(6):568-79. doi: 10.1056/NEJMoa0706135.

3.

PREDICT-1 (CNA106030): the first powered, prospective trial of pharmacogenetic screening to reduce drug adverse events.

Hughes S, Hughes A, Brothers C, Spreen W, Thorborn D; CNA106030 Study Team.

Pharm Stat. 2008 Apr-Jun;7(2):121-9.

PMID:
17534855
4.

Early induction of leukemia inhibitor factor (LIF) in acute HIV-1 infection.

Tjernlund A, Barqasho B, Nowak P, Kinloch S, Thorborn D, Perrin L, Sönnerborg A, Walther-Jallow L, Andersson J.

AIDS. 2006 Jan 2;20(1):11-9.

PMID:
16327314
5.

Intracellular cytokines may model immunoregulation of abacavir hypersensitivity in HIV-infected subjects.

King D, Tomkins S, Waters A, Easterbrook PJ, Thurmond LM, Thorborn DE, Raffi F, Kemeny DM, Vyakarnam A.

J Allergy Clin Immunol. 2005 May;115(5):1081-7.

PMID:
15867870
6.

Polyamine and thiol metabolism in Trypanosoma granulosum: similarities with Trypanosoma cruzi.

Mastri C, Thorborn DE, Davies AJ, Ariyanayagam MR, Hunter KJ.

Biochem Biophys Res Commun. 2001 Apr 20;282(5):1177-82.

PMID:
11302739
7.

Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial.

Staszewski S, Keiser P, Montaner J, Raffi F, Gathe J, Brotas V, Hicks C, Hammer SM, Cooper D, Johnson M, Tortell S, Cutrell A, Thorborn D, Isaacs R, Hetherington S, Steel H, Spreen W; CNAAB3005 International Study Team.

JAMA. 2001 Mar 7;285(9):1155-63. Erratum in: JAMA 2001 Jun 13;285(22):2858.

PMID:
11231744
8.

Uptake of putrescine by Trypanosoma granulosum.

Mastri C, Rytlewski F, Thorborn D, Davies AJ, Sappal G.

Biochem Soc Trans. 1998 Nov;26(4):S376. No abstract available.

PMID:
10047890

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