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Items: 1 to 50 of 147

1.

Ion Mobility Mass Spectrometry as an Efficient Tool for Identification of Streptorubin B in Streptomyces coelicolor M145.

Marshall AP, Johnson AR, Vega MM, Thomson RJ, Carlson EE.

J Nat Prod. 2020 Jan 6. doi: 10.1021/acs.jnatprod.9b00828. [Epub ahead of print]

PMID:
31904955
2.

Synthesis and surface spectroscopy of α-pinene isotopologues and their corresponding secondary organic material.

Upshur MA, Vega MM, Bé AG, Chase HM, Zhang Y, Tuladhar A, Chase ZA, Fu L, Ebben CJ, Wang Z, Martin ST, Geiger FM, Thomson RJ.

Chem Sci. 2019 Jul 31;10(36):8390-8398. doi: 10.1039/c9sc02399b. eCollection 2019 Sep 28.

3.

A computational framework to explore large-scale biosynthetic diversity.

Navarro-Muñoz JC, Selem-Mojica N, Mullowney MW, Kautsar SA, Tryon JH, Parkinson EI, De Los Santos ELC, Yeong M, Cruz-Morales P, Abubucker S, Roeters A, Lokhorst W, Fernandez-Guerra A, Cappelini LTD, Goering AW, Thomson RJ, Metcalf WW, Kelleher NL, Barona-Gomez F, Medema MH.

Nat Chem Biol. 2020 Jan;16(1):60-68. doi: 10.1038/s41589-019-0400-9. Epub 2019 Nov 25.

PMID:
31768033
4.

Efficient Blocking of Enterovirus 71 Infection by Heparan Sulfate Analogues Acting as Decoy Receptors.

Earley DF, Bailly B, Maggioni A, Kundur AR, Thomson RJ, Chang CW, von Itzstein M.

ACS Infect Dis. 2019 Oct 11;5(10):1708-1717. doi: 10.1021/acsinfecdis.9b00070. Epub 2019 Aug 5.

PMID:
31307190
5.

New Genetic Loci Associated With Chronic Kidney Disease in an Indigenous Australian Population.

Thomson RJ, McMorran B, Hoy W, Jose M, Whittock L, Thornton T, Burgio G, Mathews JD, Foote S.

Front Genet. 2019 Apr 16;10:330. doi: 10.3389/fgene.2019.00330. eCollection 2019.

6.

New antiviral approaches for human parainfluenza: Inhibiting the haemagglutinin-neuraminidase.

Chibanga VP, Dirr L, Guillon P, El-Deeb IM, Bailly B, Thomson RJ, von Itzstein M.

Antiviral Res. 2019 Jul;167:89-97. doi: 10.1016/j.antiviral.2019.04.001. Epub 2019 Apr 3. Review.

PMID:
30951732
7.

Automated localization and quality control of the aorta in cine CMR can significantly accelerate processing of the UK Biobank population data.

Biasiolli L, Hann E, Lukaschuk E, Carapella V, Paiva JM, Aung N, Rayner JJ, Werys K, Fung K, Puchta H, Sanghvi MM, Moon NO, Thomson RJ, Thomas KE, Robson MD, Grau V, Petersen SE, Neubauer S, Piechnik SK.

PLoS One. 2019 Feb 14;14(2):e0212272. doi: 10.1371/journal.pone.0212272. eCollection 2019.

8.

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA Jr, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.

ACS Cent Sci. 2018 Dec 26;4(12):1727-1741. doi: 10.1021/acscentsci.8b00747. Epub 2018 Dec 5.

9.

Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes: Insights From the UK Biobank Population Imaging Study.

Aung N, Sanghvi MM, Zemrak F, Lee AM, Cooper JA, Paiva JM, Thomson RJ, Fung K, Khanji MY, Lukaschuk E, Carapella V, Kim YJ, Munroe PB, Piechnik SK, Neubauer S, Petersen SE.

Circulation. 2018 Nov 13;138(20):2175-2186. doi: 10.1161/CIRCULATIONAHA.118.034856. Epub 2018 Aug 2.

10.

Natural products from thioester reductase containing biosynthetic pathways.

Mullowney MW, McClure RA, Robey MT, Kelleher NL, Thomson RJ.

Nat Prod Rep. 2018 Sep 19;35(9):847-878. doi: 10.1039/c8np00013a. Review.

11.

Correction to "A Strategy for the Convergent and Stereoselective Assembly of Polycyclic Molecules".

Robinson EE, Thomson RJ.

J Am Chem Soc. 2018 Jun 6;140(22):7043. doi: 10.1021/jacs.8b04547. Epub 2018 May 21. No abstract available.

PMID:
29781604
12.

Structural Insights into Human Parainfluenza Virus 3 Hemagglutinin-Neuraminidase Using Unsaturated 3- N-Substituted Sialic Acids as Probes.

Pascolutti M, Dirr L, Guillon P, Van Den Bergh A, Ve T, Thomson RJ, von Itzstein M.

ACS Chem Biol. 2018 Jun 15;13(6):1544-1550. doi: 10.1021/acschembio.8b00150. Epub 2018 May 21.

PMID:
29693380
13.

Distinct child-to-adult body mass index trajectories are associated with different levels of adult cardiometabolic risk.

Buscot MJ, Thomson RJ, Juonala M, Sabin MA, Burgner DP, Lehtimäki T, Hutri-Kähönen N, Viikari JSA, Raitakari OT, Magnussen CG.

Eur Heart J. 2018 Jun 21;39(24):2263-2270. doi: 10.1093/eurheartj/ehy161.

PMID:
29635282
14.

Total Synthesis of Tambromycin Enabled by Indole C-H Functionalization.

Miley GP, Rote JC, Silverman RB, Kelleher NL, Thomson RJ.

Org Lett. 2018 Apr 20;20(8):2369-2373. doi: 10.1021/acs.orglett.8b00700. Epub 2018 Mar 27.

15.

Variation in lung function and alterations in cardiac structure and function-Analysis of the UK Biobank cardiovascular magnetic resonance imaging substudy.

Thomson RJ, Aung N, Sanghvi MM, Paiva JM, Lee AM, Zemrak F, Fung K, Pfeffer PE, Mackay AJ, McKeever TM, Lukaschuk E, Carapella V, Kim YJ, Bolton CE, Piechnik SK, Neubauer S, Petersen SE.

PLoS One. 2018 Mar 20;13(3):e0194434. doi: 10.1371/journal.pone.0194434. eCollection 2018.

16.

The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study.

Sanghvi MM, Aung N, Cooper JA, Paiva JM, Lee AM, Zemrak F, Fung K, Thomson RJ, Lukaschuk E, Carapella V, Kim YJ, Harvey NC, Piechnik SK, Neubauer S, Petersen SE.

PLoS One. 2018 Mar 8;13(3):e0194015. doi: 10.1371/journal.pone.0194015. eCollection 2018.

17.

Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics.

Parkinson EI, Tryon JH, Goering AW, Ju KS, McClure RA, Kemball JD, Zhukovsky S, Labeda DP, Thomson RJ, Kelleher NL, Metcalf WW.

ACS Chem Biol. 2018 Apr 20;13(4):1029-1037. doi: 10.1021/acschembio.7b01089. Epub 2018 Mar 13.

18.

Interactive responses of primary producers and grazers to pollution on temperate rocky reefs.

Fowles AE, Stuart-Smith RD, Hill NA, Thomson RJ, Strain EMA, Alexander TJ, Kirkpatrick J, Edgar GJ.

Environ Pollut. 2018 Jun;237:388-395. doi: 10.1016/j.envpol.2018.02.061. Epub 2018 Mar 15.

PMID:
29502001
19.

A Sulfonozanamivir Analogue Has Potent Anti-influenza Virus Activity.

Hadházi Á, Li L, Bailly B, Maggioni A, Martin G, Dirr L, Dyason JC, Thomson RJ, Gao GF, Borbás A, Ve T, Pascolutti M, von Itzstein M.

ChemMedChem. 2018 Apr 23;13(8):785-789. doi: 10.1002/cmdc.201800092. Epub 2018 Mar 15.

PMID:
29453852
20.

A Strategy for the Convergent and Stereoselective Assembly of Polycyclic Molecules.

Robinson EE, Thomson RJ.

J Am Chem Soc. 2018 Feb 7;140(5):1956-1965. doi: 10.1021/jacs.7b13234. Epub 2018 Jan 24. Erratum in: J Am Chem Soc. 2018 Jun 6;140(22):7043.

PMID:
29309727
21.

Impact of the G84E variant on HOXB13 gene and protein expression in formalin-fixed, paraffin-embedded prostate tumours.

FitzGerald LM, Raspin K, Marthick JR, Field MA, Malley RC, Thomson RJ, Blackburn NB, Banks A, Charlesworth JC, Donovan S, Dickinson JL.

Sci Rep. 2017 Dec 19;7(1):17778. doi: 10.1038/s41598-017-18217-w.

22.

BMI Trajectories Associated With Resolution of Elevated Youth BMI and Incident Adult Obesity.

Buscot MJ, Thomson RJ, Juonala M, Sabin MA, Burgner DP, Lehtimäki T, Hutri-Kähönen N, Viikari JSA, Jokinen E, Tossavainen P, Laitinen T, Raitakari OT, Magnussen CG.

Pediatrics. 2018 Jan;141(1). pii: e20172003. doi: 10.1542/peds.2017-2003. Epub 2017 Dec 19.

23.

Asymmetric Traceless Petasis Borono-Mannich Reactions of Enals: Reductive Transposition of Allylic Diazenes.

Jiang Y, Thomson RJ, Schaus SE.

Angew Chem Int Ed Engl. 2017 Dec 22;56(52):16631-16635. doi: 10.1002/anie.201708784. Epub 2017 Dec 4.

24.

Abundance and local-scale processes contribute to multi-phyla gradients in global marine diversity.

Edgar GJ, Alexander TJ, Lefcheck JS, Bates AE, Kininmonth SJ, Thomson RJ, Duffy JE, Costello MJ, Stuart-Smith RD.

Sci Adv. 2017 Oct 18;3(10):e1700419. doi: 10.1126/sciadv.1700419. eCollection 2017 Oct.

25.

Meta-analysis of transcriptomic datasets identifies genes enriched in the mammalian circadian pacemaker.

Brown LA, Williams J, Taylor L, Thomson RJ, Nolan PM, Foster RG, Peirson SN.

Nucleic Acids Res. 2017 Sep 29;45(17):9860-9873. doi: 10.1093/nar/gkx714.

26.

Cloud Activation Potentials for Atmospheric α-Pinene and β-Caryophyllene Ozonolysis Products.

Gray Bé A, Upshur MA, Liu P, Martin ST, Geiger FM, Thomson RJ.

ACS Cent Sci. 2017 Jul 26;3(7):715-725. doi: 10.1021/acscentsci.7b00112. Epub 2017 Jul 5.

27.

Bayesian hierarchical piecewise regression models: a tool to detect trajectory divergence between groups in long-term observational studies.

Buscot MJ, Wotherspoon SS, Magnussen CG, Juonala M, Sabin MA, Burgner DP, Lehtimäki T, Viikari JSA, Hutri-Kähönen N, Raitakari OT, Thomson RJ.

BMC Med Res Methodol. 2017 Jun 6;17(1):86. doi: 10.1186/s12874-017-0358-9.

28.

Consistent multi-level trophic effects of marine reserve protection across northern New Zealand.

Edgar GJ, Stuart-Smith RD, Thomson RJ, Freeman DJ.

PLoS One. 2017 May 24;12(5):e0177216. doi: 10.1371/journal.pone.0177216. eCollection 2017.

29.

A sialosyl sulfonate as a potent inhibitor of influenza virus replication.

Hadházi Á, Pascolutti M, Bailly B, Dyason JC, Borbás A, Thomson RJ, von Itzstein M.

Org Biomol Chem. 2017 Jun 27;15(25):5249-5253. doi: 10.1039/c7ob00947j.

PMID:
28540971
30.

Triflimide-catalyzed allylsilane annulations of benzylic alcohols for the divergent synthesis of indanes and tetralins.

Reddel JCT, Wang W, Koukounas K, Thomson RJ.

Chem Sci. 2017 Mar 1;8(3):2156-2160. doi: 10.1039/c6sc04762a. Epub 2016 Dec 9.

31.

Highly Oxygenated Multifunctional Compounds in α-Pinene Secondary Organic Aerosol.

Zhang X, Lambe AT, Upshur MA, Brooks WA, Gray Bé A, Thomson RJ, Geiger FM, Surratt JD, Zhang Z, Gold A, Graf S, Cubison MJ, Groessl M, Jayne JT, Worsnop DR, Canagaratna MR.

Environ Sci Technol. 2017 Jun 6;51(11):5932-5940. doi: 10.1021/acs.est.6b06588. Epub 2017 May 10.

PMID:
28445044
32.

Enantioselective Synthesis of Allenes by Catalytic Traceless Petasis Reactions.

Jiang Y, Diagne AB, Thomson RJ, Schaus SE.

J Am Chem Soc. 2017 Feb 8;139(5):1998-2005. doi: 10.1021/jacs.6b11937. Epub 2017 Jan 25.

33.

Unanticipated Stickiness of α-Pinene.

Chase HM, Ho J, Upshur MA, Thomson RJ, Batista VS, Geiger FM.

J Phys Chem A. 2017 May 4;121(17):3239-3246. doi: 10.1021/acs.jpca.6b12653. Epub 2017 Feb 13.

PMID:
28100048
34.

Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations.

McClure RA, Goering AW, Ju KS, Baccile JA, Schroeder FC, Metcalf WW, Thomson RJ, Kelleher NL.

ACS Chem Biol. 2016 Dec 16;11(12):3452-3460. Epub 2016 Nov 15.

35.

Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopy.

Madge PD, Maggioni A, Pascolutti M, Amin M, Waespy M, Bellette B, Thomson RJ, Kelm S, von Itzstein M, Haselhorst T.

Sci Rep. 2016 Nov 3;6:36012. doi: 10.1038/srep36012.

36.

A cross-continental comparison of plant and beetle responses to retention of forest patches during timber harvest.

Baker SC, Halpern CB, Wardlaw TJ, Kern C, Edgar GJ, Thomson RJ, Bigley RE, Franklin JF, Gandhi KJ, Gustafsson L, Johnson S, Palik BJ, Spies TA, Steel EA, Weslien J, Strengbom J.

Ecol Appl. 2016 Dec;26(8):2493-2504. doi: 10.1002/eap.1406. Epub 2016 Oct 27.

PMID:
27787926
37.

Leadership and management in UK medical school curricula.

Jefferies R, Sheriff IH, Matthews JH, Jagger O, Curtis S, Lees P, Spurgeon PC, Fountain DM, Oldman A, Habib A, Saied A, Court J, Giannoudi M, Sayma M, Ward N, Cork N, Olatokun O, Devine O, O'Connell P, Carr P, Kotronias RA, Gardiner R, Buckle RT, Thomson RJ, Williams S, Nicholson SJ, Goga U.

J Health Organ Manag. 2016 Oct 10;30(7):1081-1104.

PMID:
27700475
38.

In Vitro Reconstruction of Nonribosomal Peptide Biosynthesis Directly from DNA Using Cell-Free Protein Synthesis.

Goering AW, Li J, McClure RA, Thomson RJ, Jewett MC, Kelleher NL.

ACS Synth Biol. 2017 Jan 20;6(1):39-44. doi: 10.1021/acssynbio.6b00160. Epub 2016 Aug 9.

39.

Structure, Chemical Synthesis, and Biosynthesis of Prodiginine Natural Products.

Hu DX, Withall DM, Challis GL, Thomson RJ.

Chem Rev. 2016 Jul 27;116(14):7818-53. doi: 10.1021/acs.chemrev.6b00024. Epub 2016 Jun 17. Review.

40.

New Aspercryptins, Lipopeptide Natural Products, Revealed by HDAC Inhibition in Aspergillus nidulans.

Henke MT, Soukup AA, Goering AW, McClure RA, Thomson RJ, Keller NP, Kelleher NL.

ACS Chem Biol. 2016 Aug 19;11(8):2117-23. doi: 10.1021/acschembio.6b00398. Epub 2016 Jun 24.

41.

Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer.

Goering AW, McClure RA, Doroghazi JR, Albright JC, Haverland NA, Zhang Y, Ju KS, Thomson RJ, Metcalf WW, Kelleher NL.

ACS Cent Sci. 2016 Feb 24;2(2):99-108. doi: 10.1021/acscentsci.5b00331. Epub 2016 Jan 20.

42.

Vibrational Mode Assignment of α-Pinene by Isotope Editing: One Down, Seventy-One To Go.

Upshur MA, Chase HM, Strick BF, Ebben CJ, Fu L, Wang H, Thomson RJ, Geiger FM.

J Phys Chem A. 2016 May 5;120(17):2684-90. doi: 10.1021/acs.jpca.6b01995. Epub 2016 Apr 26.

PMID:
27063197
43.

The Combined Effect of Common Genetic Risk Variants on Circulating Lipoproteins Is Evident in Childhood: A Longitudinal Analysis of the Cardiovascular Risk in Young Finns Study.

Buscot MJ, Magnussen CG, Juonala M, Pitkänen N, Lehtimäki T, Viikari JS, Kähönen M, Hutri-Kähönen N, Schork NJ, Raitakari OT, Thomson RJ.

PLoS One. 2016 Jan 5;11(1):e0146081. doi: 10.1371/journal.pone.0146081. eCollection 2016.

44.

Functional and structural characterization of a heparanase.

Bohlmann L, Tredwell GD, Yu X, Chang CW, Haselhorst T, Winger M, Dyason JC, Thomson RJ, Tiralongo J, Beacham IR, Blanchard H, von Itzstein M.

Nat Chem Biol. 2015 Dec;11(12):955-7. doi: 10.1038/nchembio.1956. Epub 2015 Nov 2.

PMID:
26565989
45.

Assessment of DFT for Computing Sum Frequency Generation Spectra of an Epoxydiol and a Deuterated Isotopologue at Fused Silica/Vapor Interfaces.

Chase HM, Rudshteyn B, Psciuk BT, Upshur MA, Strick BF, Thomson RJ, Batista VS, Geiger FM.

J Phys Chem B. 2016 Mar 3;120(8):1919-27. doi: 10.1021/acs.jpcb.5b09769. Epub 2015 Nov 30.

PMID:
26562617
46.

SAMDI Mass Spectrometry-Enabled High-Throughput Optimization of a Traceless Petasis Reaction.

Diagne AB, Li S, Perkowski GA, Mrksich M, Thomson RJ.

ACS Comb Sci. 2015 Nov 9;17(11):658-62. doi: 10.1021/acscombsci.5b00131. Epub 2015 Nov 1.

PMID:
26521847
47.

Methodological Factors in Determining Risk of Dementia After Transient Ischemic Attack and Stroke: (III) Applicability of Cognitive Tests.

Pendlebury ST, Klaus SP, Thomson RJ, Mehta Z, Wharton RM, Rothwell PM; Oxford Vascular Study.

Stroke. 2015 Nov;46(11):3067-73. doi: 10.1161/STROKEAHA.115.010290. Epub 2015 Oct 13.

48.

Reef Fishes at All Trophic Levels Respond Positively to Effective Marine Protected Areas.

Soler GA, Edgar GJ, Thomson RJ, Kininmonth S, Campbell SJ, Dawson TP, Barrett NS, Bernard AT, Galván DE, Willis TJ, Alexander TJ, Stuart-Smith RD.

PLoS One. 2015 Oct 13;10(10):e0140270. doi: 10.1371/journal.pone.0140270. eCollection 2015.

49.

Atypical group 1 neuraminidase pH1N1-N1 bound to a group 1 inhibitor.

Wu Y, Vavricka CJ, Wu Y, Li Q, Rudrawar S, Thomson RJ, von Itzstein M, Gao GF, Qi J.

Protein Cell. 2015 Oct;6(10):771-3. doi: 10.1007/s13238-015-0197-6. No abstract available.

50.

Total Synthesis of the Galbulimima Alkaloids Himandravine and GB17 Using Biomimetic Diels-Alder Reactions of Double Diene Precursors.

Larson RT, Pemberton RP, Franke JM, Tantillo DJ, Thomson RJ.

J Am Chem Soc. 2015 Sep 2;137(34):11197-204. doi: 10.1021/jacs.5b07710. Epub 2015 Aug 25.

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