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Items: 1 to 50 of 88

1.

Virus Delivery of CRISPR Guides to the Murine Prostate for Gene Alteration.

Riedel M, Berthelsen MF, Bakiri L, Wagner EF, Thomsen MK.

J Vis Exp. 2018 Apr 27;(134). doi: 10.3791/57525.

PMID:
29757291
2.

STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice.

Skouboe MK, Knudsen A, Reinert LS, Boularan C, Lioux T, Perouzel E, Thomsen MK, Paludan SR.

PLoS Pathog. 2018 Apr 2;14(4):e1006976. doi: 10.1371/journal.ppat.1006976. eCollection 2018 Apr.

3.

Probing Cyclic π-Electron Delocalization in an Imidazol-2-ylidene and a Corresponding Imidazolium Salt.

Thomsen MK, Gatti C, Overgaard J.

Chemistry. 2018 Apr 3;24(19):4973-4981. doi: 10.1002/chem.201800014. Epub 2018 Mar 2.

PMID:
29364550
4.

A genetically inducible porcine model of intestinal cancer.

Callesen MM, Árnadóttir SS, Lyskjaer I, Ørntoft MW, Høyer S, Dagnaes-Hansen F, Liu Y, Li R, Callesen H, Rasmussen MH, Berthelsen MF, Thomsen MK, Schweiger PJ, Jensen KB, Laurberg S, Ørntoft TF, Elverløv-Jakobsen JE, Andersen CL.

Mol Oncol. 2017 Nov;11(11):1616-1629. doi: 10.1002/1878-0261.12136. Epub 2017 Oct 10.

5.

Pancreas specific expression of oncogenes in a porcine model.

Berthelsen MF, Callesen MM, Østergaard TS, Liu Y, Li R, Callesen H, Dagnæs-Hansen F, Hamilton-Dutoit S, Jakobsen JE, Thomsen MK.

Transgenic Res. 2017 Oct;26(5):603-612. doi: 10.1007/s11248-017-0031-4. Epub 2017 Jun 29.

PMID:
28664456
6.

Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation.

Bakiri L, Hamacher R, Graña O, Guío-Carrión A, Campos-Olivas R, Martinez L, Dienes HP, Thomsen MK, Hasenfuss SC, Wagner EF.

J Exp Med. 2017 May 1;214(5):1387-1409. doi: 10.1084/jem.20160935. Epub 2017 Mar 29.

7.

Validity of data in the Danish Colorectal Cancer Screening Database.

Thomsen MK, Njor SH, Rasmussen M, Linnemann D, Andersen B, Baatrup G, Friis-Hansen LJ, Jørgensen JC, Mikkelsen EM.

Clin Epidemiol. 2017 Feb 17;9:105-111. doi: 10.2147/CLEP.S124454. eCollection 2017.

8.

Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.

Reinert LS, Lopušná K, Winther H, Sun C, Thomsen MK, Nandakumar R, Mogensen TH, Meyer M, Vægter C, Nyengaard JR, Fitzgerald KA, Paludan SR.

Nat Commun. 2016 Nov 10;7:13348. doi: 10.1038/ncomms13348.

9.

Description and characterization of a penicillin-resistant Streptococcus dysgalactiae subsp. equisimilis clone isolated from blood in three epidemiologically linked patients.

Fuursted K, Stegger M, Hoffmann S, Lambertsen L, Andersen PS, Deleuran M, Thomsen MK.

J Antimicrob Chemother. 2016 Dec;71(12):3376-3380. Epub 2016 Sep 1.

PMID:
27585966
10.

Electron Density Analysis of the "O-O" Charge-Shift Bonding in Rubrene Endoperoxide.

Hathwar VR, Thomsen MK, Mamakhel MA, Filsø MØ, Overgaard J, Iversen BB.

J Phys Chem A. 2016 Sep 29;120(38):7510-8. doi: 10.1021/acs.jpca.6b06588. Epub 2016 Sep 14.

PMID:
27584148
11.

Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection.

Thomsen MK, Nandakumar R, Stadler D, Malo A, Valls RM, Wang F, Reinert LS, Dagnaes-Hansen F, Hollensen AK, Mikkelsen JG, Protzer U, Paludan SR.

Hepatology. 2016 Sep;64(3):746-59. doi: 10.1002/hep.28685. Epub 2016 Jul 26.

PMID:
27312012
12.

Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 - a rapid epidemiological and virological assessment.

Emborg HD, Krause TG, Nielsen L, Thomsen MK, Christiansen CB, Skov MN, Nielsen XC, Weinreich LS, Fischer TK, Rønn J, Trebbien R.

Euro Surveill. 2016;21(14). doi: 10.2807/1560-7917.ES.2016.21.14.30189.

13.

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.

Holm CK, Rahbek SH, Gad HH, Bak RO, Jakobsen MR, Jiang Z, Hansen AL, Jensen SK, Sun C, Thomsen MK, Laustsen A, Nielsen CG, Severinsen K, Xiong Y, Burdette DL, Hornung V, Lebbink RJ, Duch M, Fitzgerald KA, Bahrami S, Mikkelsen JG, Hartmann R, Paludan SR.

Nat Commun. 2016 Feb 19;7:10680. doi: 10.1038/ncomms10680.

14.

Structural Collapse of the Hydroquinone-Formic Acid Clathrate: A Pressure-Medium-Dependent Phase Transition.

Eikeland E, Thomsen MK, Madsen SR, Overgaard J, Spackman MA, Iversen BB.

Chemistry. 2016 Mar 14;22(12):4061-9. doi: 10.1002/chem.201504908. Epub 2016 Feb 16.

PMID:
26879515
15.

An innate antiviral pathway acting before interferons at epithelial surfaces.

Iversen MB, Reinert LS, Thomsen MK, Bagdonaite I, Nandakumar R, Cheshenko N, Prabakaran T, Vakhrushev SY, Krzyzowska M, Kratholm SK, Ruiz-Perez F, Petersen SV, Goriely S, Bibby BM, Eriksson K, Ruland J, Thomsen AR, Herold BC, Wandall HH, Frische S, Holm CK, Paludan SR.

Nat Immunol. 2016 Feb;17(2):150-8. doi: 10.1038/ni.3319. Epub 2015 Nov 30.

PMID:
26595890
16.

Population pharmacokinetics of piperacillin in the early phase of septic shock: does standard dosing result in therapeutic plasma concentrations?

Öbrink-Hansen K, Juul RV, Storgaard M, Thomsen MK, Hardlei TF, Brock B, Kreilgaard M, Gjedsted J.

Antimicrob Agents Chemother. 2015 Nov;59(11):7018-26. doi: 10.1128/AAC.01347-15. Epub 2015 Sep 8.

17.

Chemical bonding and electronic localization in a Ga(I) amide.

Thomsen MK, Dange D, Jones C, Overgaard J.

Chemistry. 2015 Oct 5;21(41):14460-70. doi: 10.1002/chem.201500760. Epub 2015 Aug 21.

PMID:
26296814
18.

Clinical and biochemical characteristics of patients with Fusobacterium necrophorum-positive acute tonsillitis.

Kjærulff AM, Thomsen MK, Ovesen T, Klug TE.

Eur Arch Otorhinolaryngol. 2015 Jun;272(6):1457-63. doi: 10.1007/s00405-015-3535-7. Epub 2015 Feb 10.

PMID:
25876001
19.

Effectiveness of anti-tumour necrosis factor-α therapy in Danish patients with inflammatory bowel diseases.

Bank S, Andersen PS, Burisch J, Pedersen N, Roug S, Galsgaard J, Turino SY, Brodersen JB, Rashid S, Avlund S, Olesen TB, Green A, Hoffmann HJ, Thomsen MK, Thomsen VØ, Nexø BA, Vogel U, Andersen V.

Dan Med J. 2015 Mar;62(3). pii: A4994.

PMID:
25748864
20.

Loss of JUNB/AP-1 promotes invasive prostate cancer.

Thomsen MK, Bakiri L, Hasenfuss SC, Wu H, Morente M, Wagner EF.

Cell Death Differ. 2015 Apr;22(4):574-82. doi: 10.1038/cdd.2014.213. Epub 2014 Dec 19.

21.

Chemical bonding in a linear chromium metal string complex.

Wu LC, Thomsen MK, Madsen SR, Schmoekel M, Jørgensen MR, Cheng MC, Peng SM, Chen YS, Overgaard J, Iversen BB.

Inorg Chem. 2014 Dec 1;53(23):12489-98. doi: 10.1021/ic501603x. Epub 2014 Nov 10.

PMID:
25383889
22.

Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.

Sode J, Vogel U, Bank S, Andersen PS, Thomsen MK, Hetland ML, Locht H, Heegaard NH, Andersen V.

PLoS One. 2014 Jun 26;9(6):e100361. doi: 10.1371/journal.pone.0100361. eCollection 2014.

23.

Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease.

Bank S, Andersen PS, Burisch J, Pedersen N, Roug S, Galsgaard J, Turino SY, Brodersen JB, Rashid S, Rasmussen BK, Avlund S, Olesen TB, Hoffmann HJ, Thomsen MK, Thomsen VØ, Frydenberg M, Nexø BA, Sode J, Vogel U, Andersen V.

Pharmacogenomics J. 2014 Dec;14(6):526-34. doi: 10.1038/tpj.2014.19. Epub 2014 Apr 29.

PMID:
24776844
24.

Are procalcitonin or other infection markers useful in the detection of group A streptococcal acute tonsillitis?

Christensen AM, Thomsen MK, Ovesen T, Klug TE.

Scand J Infect Dis. 2014 May;46(5):376-83. doi: 10.3109/00365548.2014.885656. Epub 2014 Mar 10.

PMID:
24606046
25.

Mads Krogsgaard Thomsen. Interview by Asher Mullard.

Thomsen MK.

Nat Rev Drug Discov. 2014 Feb;13(2):96-7. doi: 10.1038/nrd4238. No abstract available.

PMID:
24481301
26.

Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers.

Hasenfuss SC, Bakiri L, Thomsen MK, Williams EG, Auwerx J, Wagner EF.

Cell Metab. 2014 Jan 7;19(1):84-95. doi: 10.1016/j.cmet.2013.11.018.

27.

JUNB/AP-1 controls IFN-γ during inflammatory liver disease.

Thomsen MK, Bakiri L, Hasenfuss SC, Hamacher R, Martinez L, Wagner EF.

J Clin Invest. 2013 Dec;123(12):5258-68. doi: 10.1172/JCI70405. Epub 2013 Nov 8.

28.

A structural study of a three-membered linear metal chain compound at elevated pressure.

Madsen SR, Thomsen MK, Scheins S, Chen YS, Finkelmeier N, Stalke D, Overgaard J, Iversen BB.

Dalton Trans. 2014 Jan 21;43(3):1313-20. doi: 10.1039/c3dt52035h. Epub 2013 Nov 5.

PMID:
24192864
29.

Formation of radicals during heating lysine and glucose in solution with an intermediate water activity.

Yin J, Andersen ML, Thomsen MK, Skibsted LH, Hedegaard RV.

Free Radic Res. 2013 Aug;47(8):643-50. doi: 10.3109/10715762.2013.812206. Epub 2013 Jun 28.

PMID:
23745613
30.

Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism.

Hasenfuss SC, Bakiri L, Thomsen MK, Hamacher R, Wagner EF.

Hepatology. 2014 Jan;59(1):261-73. doi: 10.1002/hep.26518. Epub 2013 Oct 10.

PMID:
23703832
31.

β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.

Francis JC, Thomsen MK, Taketo MM, Swain A.

PLoS Genet. 2013;9(1):e1003180. doi: 10.1371/journal.pgen.1003180. Epub 2013 Jan 3.

32.

Scrutinizing negative thermal expansion in MOF-5 by scattering techniques and ab initio calculations.

Lock N, Christensen M, Wu Y, Peterson VK, Thomsen MK, Piltz RO, Ramirez-Cuesta AJ, McIntyre GJ, Norén K, Kutteh R, Kepert CJ, Kearley GJ, Iversen BB.

Dalton Trans. 2013 Feb 14;42(6):1996-2007. doi: 10.1039/c2dt31491f.

PMID:
23044752
33.

21 Days head-down bed rest induces weakening of cell-mediated immunity - Some spaceflight findings confirmed in a ground-based analog.

Kelsen J, Bartels LE, Dige A, Hvas CL, Frings-Meuthen P, Boehme G, Thomsen MK, Fenger-Grøn M, Dahlerup JF.

Cytokine. 2012 Aug;59(2):403-9. doi: 10.1016/j.cyto.2012.04.032. Epub 2012 May 15.

PMID:
22595648
34.

National surveillance of fungemia in Denmark (2004 to 2009).

Arendrup MC, Bruun B, Christensen JJ, Fuursted K, Johansen HK, Kjaeldgaard P, Knudsen JD, Kristensen L, Møller J, Nielsen L, Rosenvinge FS, Røder B, Schønheyder HC, Thomsen MK, Truberg K.

J Clin Microbiol. 2011 Jan;49(1):325-34. doi: 10.1128/JCM.01811-10. Epub 2010 Oct 27.

35.

Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.

Francis JC, McCarthy A, Thomsen MK, Ashworth A, Swain A.

PLoS Genet. 2010 Jun 24;6(6):e1000995. doi: 10.1371/journal.pgen.1000995.

36.

SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation.

Thomsen MK, Ambroisine L, Wynn S, Cheah KS, Foster CS, Fisher G, Berney DM, Møller H, Reuter VE, Scardino P, Cuzick J, Ragavan N, Singh PB, Martin FL, Butler CM, Cooper CS, Swain A; Transatlantic Prostate Group.

Cancer Res. 2010 Feb 1;70(3):979-87. doi: 10.1158/0008-5472.CAN-09-2370. Epub 2010 Jan 26.

37.

Vancomycin-resistant Enterococcus spp.: validation of susceptibility testing and in vitro activity of vancomycin, linezolid, tigecycline and daptomycin.

Rathe M, Kristensen L, Ellermann-Eriksen S, Thomsen MK, Schumacher H.

APMIS. 2010 Jan;118(1):66-73. doi: 10.1111/j.1600-0463.2009.02559.x.

PMID:
20041873
38.

Galectin-2 at the enterocyte brush border of the small intestine.

Thomsen MK, Hansen GH, Danielsen EM.

Mol Membr Biol. 2009 Aug;26(5):347-55. doi: 10.1080/09687680903167781. Epub 2009 Aug 5.

PMID:
19657968
39.

[Abortion due to non-capsulated Haemophilus influenzae].

Fuglsang K, Thomsen MK, Holmskov A.

Ugeskr Laeger. 2009 May 4;171(19):1610-1. Danish.

PMID:
19419646
40.

The role of Sox9 in prostate development.

Thomsen MK, Francis JC, Swain A.

Differentiation. 2008 Jul;76(6):728-35. doi: 10.1111/j.1432-0436.2008.00293.x. Epub 2008 Jun 28. Review.

PMID:
18557758
41.

Sox9 is required for prostate development.

Thomsen MK, Butler CM, Shen MM, Swain A.

Dev Biol. 2008 Apr 15;316(2):302-11. doi: 10.1016/j.ydbio.2008.01.030. Epub 2008 Feb 7.

42.

Global health: the ethical responsibility of the pharmaceutical industry.

Lassen LC, Thomsen MK.

Dan Med Bull. 2007 Feb;54(1):35-6.

PMID:
17349219
43.

[Global health--the ethical responsibility of the pharmaceutical industry].

Lassen LC, Thomsen MK.

Ugeskr Laeger. 2006 Sep 4;168(36):2994-5. Danish.

PMID:
16999884
44.

Clonal spread of Staphylococcus aureus with reduced susceptibility to oxacillin in a dermatological hospital unit.

Thomsen MK, Rasmussen M, Fuursted K, Westh H, Pedersen LN, Deleuran M, Møller JK.

Acta Derm Venereol. 2006;86(3):230-4.

45.

Water activity-temperature state diagram of amorphous lactose.

Thomsen MK, Jespersen L, Sjøstrøm K, Risbo J, Skibsted LH.

J Agric Food Chem. 2005 Nov 16;53(23):9182-5.

PMID:
16277420
46.

[The role of hepatobiliary scintigraphy in neonates with persistant jaundice].

Thomsen MK, Lange A, Frøkiaer J.

Ugeskr Laeger. 2005 Sep 26;167(39):3675-8. Danish.

PMID:
16219213
47.

Temperature effect on lactose crystallization, maillard reactions, and lipid oxidation in whole milk powder.

Thomsen MK, Lauridsen L, Skibsted LH, Risbo J.

J Agric Food Chem. 2005 Sep 7;53(18):7082-90.

PMID:
16131114
48.

Two types of radicals in whole milk powder. Effect of lactose crystallization, lipid oxidation, and browning reactions.

Thomsen MK, Lauridsen L, Skibsted LH, Risbo J.

J Agric Food Chem. 2005 Mar 9;53(5):1805-11.

PMID:
15740077
49.

The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency.

Østergård T, Degn KB, Gall MA, Carr RD, Veldhuis JD, Thomsen MK, Rizza RA, Schmitz O.

J Clin Endocrinol Metab. 2004 Jan;89(1):297-302.

PMID:
14715864
50.

[The roles and responsibilities of the pharmaceutical industry].

Dejgaard A, Thomsen MK.

Ugeskr Laeger. 2003 Apr 14;165(16):1676-9. Review. Danish.

PMID:
12756829

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