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Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury.

Thomas CN, Thompson AM, McCance E, Berry M, Logan A, Blanch RJ, Ahmed Z.

Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4453-4462. doi: 10.1167/iovs.18-24045.


A Guide to Understanding Reimbursement and Value-Based Care in the Military Health System.

Galvin JW, Thompson JC, Thompson AM, Parada SA, Eichinger JK, Dickens JF, Gillingham BL.

Mil Med. 2018 Aug 28. doi: 10.1093/milmed/usy206. [Epub ahead of print]


Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1.

Cha JH, Yang WH, Xia W, Wei Y, Chan LC, Lim SO, Li CW, Kim T, Chang SS, Lee HH, Hsu JL, Wang HL, Kuo CW, Chang WC, Hadad S, Purdie CA, McCoy AM, Cai S, Tu Y, Litton JK, Mittendorf EA, Moulder SL, Symmans WF, Thompson AM, Piwnica-Worms H, Chen CH, Khoo KH, Hung MC.

Mol Cell. 2018 Aug 16;71(4):606-620.e7. doi: 10.1016/j.molcel.2018.07.030.


What Is Your Diagnosis?

Stine SL, Bahr AM, Thompson AM, Lange DN.

J Am Vet Med Assoc. 2018 Sep 1;253(5):555-557. doi: 10.2460/javma.253.5.555. No abstract available.


Management and 5-year outcomes in 9938 women with screen-detected ductal carcinoma in situ: the UK Sloane Project.

Thompson AM, Clements K, Cheung S, Pinder SE, Lawrence G, Sawyer E, Kearins O, Ball GR, Tomlinson I, Hanby A, Thomas JSJ, Maxwell AJ, Wallis MG, Dodwell DJ; Sloane Project Steering Group (NHS Prospective Study of Screen-Detected Non-invasive Neoplasias).

Eur J Cancer. 2018 Sep;101:210-219. doi: 10.1016/j.ejca.2018.06.027. Epub 2018 Aug 6.


Neoadjuvant Pertuzumab-containing Regimens Improve Pathologic Complete Response Rates in Stage II to III HER-2/neu-positive Breast Cancer: A Retrospective, Single Institution Experience.

Murthy RK, Raghavendra AS, Hess KR, Fujii T, Lim B, Barcenas CH, Zhang H, Chavez-Mac-Gregor M, Mittendorf EA, Litton JK, Giordano SH, Thompson AM, Valero V, Moulder SL, Tripathy D, Ueno NT.

Clin Breast Cancer. 2018 Jul 10. pii: S1526-8209(18)30009-0. doi: 10.1016/j.clbc.2018.07.008. [Epub ahead of print]


Ozone Variability and Anomalies Observed during SENEX and SEAC4RS Campaigns in 2013.

Kuang S, Newchurch MJ, Thompson AM, Stauffer RM, Johnson BJ, Wang L.

J Geophys Res Atmos. 2017 Oct 27;122(20):11227-11241. doi: 10.1002/2017JD027139. Epub 2017 Oct 12.


Prospective Study of Psychosocial Outcomes of Having Contralateral Prophylactic Mastectomy Among Women With Nonhereditary Breast Cancer.

Parker PA, Peterson SK, Shen Y, Bedrosian I, Black DM, Thompson AM, Nelson JC, DeSnyder SM, Cook RL, Hunt KK, Volk RJ, Cantor SB, Dong W, Brewster AM.

J Clin Oncol. 2018 Sep 1;36(25):2630-2638. doi: 10.1200/JCO.2018.78.6442. Epub 2018 Jul 25.


Scoring of tumor-infiltrating lymphocytes: From visual estimation to machine learning.

Klauschen F, Müller KR, Binder A, Bockmayr M, Hägele M, Seegerer P, Wienert S, Pruneri G, de Maria S, Badve S, Michiels S, Nielsen TO, Adams S, Savas P, Symmans F, Willis S, Gruosso T, Park M, Haibe-Kains B, Gallas B, Thompson AM, Cree I, Sotiriou C, Solinas C, Preusser M, Hewitt SM, Rimm D, Viale G, Loi S, Loibl S, Salgado R, Denkert C; International Immuno-Oncology Biomarker Working Group.

Semin Cancer Biol. 2018 Oct;52(Pt 2):151-157. doi: 10.1016/j.semcancer.2018.07.001. Epub 2018 Jul 7. Review.


Treatment patterns and related clinical consequences in adults with asthma.

Dilokthornsakul P, Thompson AM, Campbell JD.

J Asthma. 2018 Aug 24:1-9. doi: 10.1080/02770903.2018.1490749. [Epub ahead of print]


Multidisciplinary Intraoperative Assessment of Breast Specimens Reduces Number of Positive Margins.

Tevis SE, Neuman HB, Mittendorf EA, Kuerer HM, Bedrosian I, DeSnyder SM, Thompson AM, Black DM, Scoggins ME, Sahin AA, Hunt KK, Caudle AS.

Ann Surg Oncol. 2018 Oct;25(10):2932-2938. doi: 10.1245/s10434-018-6607-2. Epub 2018 Jun 26.


Semaglutide: The Newest Once-Weekly GLP-1 RA for Type 2 Diabetes.

Tuchscherer RM, Thompson AM, Trujillo JM.

Ann Pharmacother. 2018 Jun 1:1060028018784583. doi: 10.1177/1060028018784583. [Epub ahead of print]


Palatable Food Affects HPA Axis Responsivity and Forebrain Neurocircuitry in an Estrous Cycle-specific Manner in Female Rats.

Egan AE, Thompson AMK, Buesing D, Fourman SM, Packard AEB, Terefe T, Li D, Wang X, Song S, Solomon MB, Ulrich-Lai YM.

Neuroscience. 2018 Aug 1;384:224-240. doi: 10.1016/j.neuroscience.2018.05.030. Epub 2018 May 28.


Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 May 22;9(1):2071. doi: 10.1038/s41467-018-04198-5.


Self-digitization chip for single-cell genotyping of cancer-related mutations.

Thompson AM, Smith JL, Monroe LD, Kreutz JE, Schneider T, Fujimoto BS, Chiu DT, Radich JP, Paguirigan AL.

PLoS One. 2018 May 2;13(5):e0196801. doi: 10.1371/journal.pone.0196801. eCollection 2018.


Clinical pharmacy academic career transitions: Viewpoints from the field part 3: Learning when and how to say yes.

Jeffres MN, Blackmer AB, Thompson AM, Glode AE, Mahyari N, Thompson M.

Curr Pharm Teach Learn. 2018 Feb;10(2):133-136. doi: 10.1016/j.cptl.2017.10.016. Epub 2017 Nov 11.


Clinical pharmacy academic career transitions: Viewpoints from the fieldPart 1: Understanding feedback, evaluation, and advancement.

Blackmer AB, Thompson AM, Jeffres MN, Glode AE, Mahyari N, Thompson M.

Curr Pharm Teach Learn. 2018 Feb;10(2):123-127. doi: 10.1016/j.cptl.2017.10.017. Epub 2017 Nov 24.


Clinical pharmacy academic career transitions: Viewpoints from the field.

Blackmer AB, Thompson AM, Jeffres MN, Glode AE, Thompson M, Mahyari N.

Curr Pharm Teach Learn. 2018 Feb;10(2):121-122. doi: 10.1016/j.cptl.2017.11.001. Epub 2017 Dec 23.


Quality Control Analysis in Real-time (QC-ART): A Tool for Real-time Quality Control Assessment of Mass Spectrometry-based Proteomics Data.

Stanfill BA, Nakayasu ES, Bramer LM, Thompson AM, Ansong CK, Clauss TR, Gritsenko MA, Monroe ME, Moore RJ, Orton DJ, Piehowski PD, Schepmoes AA, Smith RD, Webb-Robertson BM, Metz TO; TEDDY Study Group.

Mol Cell Proteomics. 2018 Sep;17(9):1824-1836. doi: 10.1074/mcp.RA118.000648. Epub 2018 Apr 17.


Breast cancer: influence of tumour volume estimation method at MRI on prediction of pathological response to neoadjuvant chemotherapy.

Henderson SA, Muhammad Gowdh N, Purdie CA, Jordan LB, Evans A, Brunton T, Thompson AM, Vinnicombe S.

Br J Radiol. 2018 Jul;91(1087):20180123. doi: 10.1259/bjr.20180123. Epub 2018 May 2.


Randomised controlled trial of exercise to prevent shoulder problems in women undergoing breast cancer treatment: study protocol for the prevention of shoulder problems trial (UK PROSPER).

Bruce J, Williamson E, Lait C, Richmond H, Betteley L, Lall R, Petrou S, Rees S, Withers EJ, Lamb SE, Thompson AM; PROSPER Study Group.

BMJ Open. 2018 Mar 23;8(3):e019078. doi: 10.1136/bmjopen-2017-019078.


A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, Chu S, Healy AR, Popova G, Pastor Fernández A, Mollick T, Darekar S, Sedimbi SK, Nekulova M, Sachweh MCC, Campbell J, Higgins M, Tuck C, Popa M, Safont MM, Gelebart P, Fandalyuk Z, Thompson AM, Svensson R, Gustavsson AL, Johansson L, Färnegårdh K, Yngve U, Saleh A, Haraldsson M, D'Hollander ACA, Franco M, Zhao Y, Håkansson M, Walse B, Larsson K, Peat EM, Pelechano V, Lunec J, Vojtesek B, Carmena M, Earnshaw WC, McCarthy AR, Westwood NJ, Arsenian-Henriksson M, Lane DP, Bhatia R, McCormack E, Laín S.

Nat Commun. 2018 Mar 16;9(1):1107. doi: 10.1038/s41467-018-03441-3. Erratum in: Nat Commun. 2018 May 22;9(1):2071.


Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.

Thompson AM, O'Connor PD, Marshall AJ, Blaser A, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Wan B, Franzblau SG, Ma Z, Cooper CB, Denny WA.

J Med Chem. 2018 Mar 22;61(6):2329-2352. doi: 10.1021/acs.jmedchem.7b01581. Epub 2018 Mar 6.


Risk factors for the development of invasive cancer in unresected ductal carcinoma in situ.

Maxwell AJ, Clements K, Hilton B, Dodwell DJ, Evans A, Kearins O, Pinder SE, Thomas J, Wallis MG, Thompson AM; Sloane Project Steering Group.

Eur J Surg Oncol. 2018 Apr;44(4):429-435. doi: 10.1016/j.ejso.2017.12.007. Epub 2018 Jan 11.


Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study.

Copson ER, Maishman TC, Tapper WJ, Cutress RI, Greville-Heygate S, Altman DG, Eccles B, Gerty S, Durcan LT, Jones L, Evans DG, Thompson AM, Pharoah P, Easton DF, Dunning AM, Hanby A, Lakhani S, Eeles R, Gilbert FJ, Hamed H, Hodgson S, Simmonds P, Stanton L, Eccles DM.

Lancet Oncol. 2018 Feb;19(2):169-180. doi: 10.1016/S1470-2045(17)30891-4. Epub 2018 Jan 11.


Antitubercular Nitroimidazoles Revisited: Synthesis and Activity of the Authentic 3-Nitro Isomer of Pretomanid.

Thompson AM, Bonnet M, Lee HH, Franzblau SG, Wan B, Wong GS, Cooper CB, Denny WA.

ACS Med Chem Lett. 2017 Nov 13;8(12):1275-1280. doi: 10.1021/acsmedchemlett.7b00356. eCollection 2017 Dec 14.


Promoting a Restrictive Intraoperative Transfusion Strategy: The Influence of a Transfusion Guideline and a Novel Software Tool.

Picton P, Starr J, Kheterpal S, Thompson AML, Housey M, Sathishkumar S, Dubovoy T, Kirkpatrick N, Tremper KK, Engoren M, Ramachandran SK.

Anesth Analg. 2018 Sep;127(3):744-752. doi: 10.1213/ANE.0000000000002704.


Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.

Thompson AM, Marshall AJ, Maes L, Yarlett N, Bacchi CJ, Gaukel E, Wring SA, Launay D, Braillard S, Chatelain E, Mowbray CE, Denny WA.

Bioorg Med Chem Lett. 2018 Jan 15;28(2):207-213. doi: 10.1016/j.bmcl.2017.10.067. Epub 2017 Oct 27.


Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase 3 trial.

Hurvitz SA, Martin M, Symmans WF, Jung KH, Huang CS, Thompson AM, Harbeck N, Valero V, Stroyakovskiy D, Wildiers H, Campone M, Boileau JF, Beckmann MW, Afenjar K, Fresco R, Helms HJ, Xu J, Lin YG, Sparano J, Slamon D.

Lancet Oncol. 2018 Jan;19(1):115-126. doi: 10.1016/S1470-2045(17)30716-7. Epub 2017 Nov 23.


Are There Alternative Strategies for the Local Management of Ductal Carcinoma in Situ?

Rosso KJ, Weiss A, Thompson AM.

Surg Oncol Clin N Am. 2018 Jan;27(1):69-80. doi: 10.1016/j.soc.2017.08.002. Review.


Winning the War on Tobacco Through Leadership at the Lowest Level.

Thompson AM, Adelman WP.

Mil Med. 2017 May;182(5):1584-1586. doi: 10.7205/MILMED-D-16-00357. No abstract available.


Dietary Manipulations That Induce Ketosis Activate the HPA Axis in Male Rats and Mice: A Potential Role for Fibroblast Growth Factor-21.

Ryan KK, Packard AEB, Larson KR, Stout J, Fourman SM, Thompson AMK, Ludwick K, Habegger KM, Stemmer K, Itoh N, Perez-Tilve D, Tschöp MH, Seeley RJ, Ulrich-Lai YM.

Endocrinology. 2018 Jan 1;159(1):400-413. doi: 10.1210/en.2017-00486.


Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers.

Glodzik D, Morganella S, Davies H, Simpson PT, Li Y, Zou X, Diez-Perez J, Staaf J, Alexandrov LB, Smid M, Brinkman AB, Rye IH, Russnes H, Raine K, Purdie CA, Lakhani SR, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JWM, Børresen-Dale AL, Richardson AL, Kong G, Viari A, Easton D, Evan G, Campbell PJ, Stratton MR, Nik-Zainal S.

Nat Genet. 2017 Oct 27;49(11):1661. doi: 10.1038/ng1117-1661a.


Integration of Community Pharmacists in Transition of Care (TOC) Services: Current Trends and Pharmacist Perceptions.

Zeleznikar EA, Kroehl ME, Perica KM, Thompson AM, Trinkley KE.

J Pharm Pract. 2017 Jan 1:897190017735976. doi: 10.1177/0897190017735976. [Epub ahead of print]


Effect of Genotype-Guided Warfarin Dosing on Clinical Events and Anticoagulation Control Among Patients Undergoing Hip or Knee Arthroplasty: The GIFT Randomized Clinical Trial.

Gage BF, Bass AR, Lin H, Woller SC, Stevens SM, Al-Hammadi N, Li J, Rodríguez T Jr, Miller JP, McMillin GA, Pendleton RC, Jaffer AK, King CR, Whipple BD, Porche-Sorbet R, Napoli L, Merritt K, Thompson AM, Hyun G, Anderson JL, Hollomon W, Barrack RL, Nunley RM, Moskowitz G, Dávila-Román V, Eby CS.

JAMA. 2017 Sep 26;318(12):1115-1124. doi: 10.1001/jama.2017.11469. Erratum in: JAMA. 2018 Mar 27;319(12 ):1281.


Surgical Upstaging Rates for Vacuum Assisted Biopsy Proven DCIS: Implications for Active Surveillance Trials.

Grimm LJ, Ryser MD, Partridge AH, Thompson AM, Thomas JS, Wesseling J, Hwang ES.

Ann Surg Oncol. 2017 Nov;24(12):3534-3540. doi: 10.1245/s10434-017-6018-9. Epub 2017 Aug 9.


Beyond the Margins-Economic Costs and Complications Associated With Repeated Breast-Conserving Surgeries.

Metcalfe LN, Zysk AM, Yemul KS, Jacobs LK, Oker EE, Underwood HR, Thompson AM.

JAMA Surg. 2017 Nov 1;152(11):1084-1086. doi: 10.1001/jamasurg.2017.2661. No abstract available.


Chronic thoracoabdominal penetrating foreign body in a dog - a tranquiliser dart.

Geis TA, Pfeffer ZM, Thompson AM.

J Small Anim Pract. 2017 Oct;58(10):593. doi: 10.1111/jsap.12722. Epub 2017 Aug 1. No abstract available.


Current trials to reduce surgical intervention in ductal carcinoma in situ of the breast: Critical review.

Toss M, Miligy I, Thompson AM, Khout H, Green AR, Ellis IO, Rakha EA.

Breast. 2017 Oct;35:151-156. doi: 10.1016/j.breast.2017.07.012. Epub 2017 Jul 22. Review.


FDA Regulatory Perspectives for Studies on Hemodialysis Vascular Access.

Hurst FP, Lee RE, Thompson AM, Pullin BD, Silverstein DM.

Clin J Am Soc Nephrol. 2018 Mar 7;13(3):513-518. doi: 10.2215/CJN.02900317. Epub 2017 Jul 24.


Analysis of stereotactic biopsies performed on suspicious calcifications identified within 24 months after completion of breast conserving surgery and radiation therapy for early breast cancer: Can biopsy be obviated?

Candelaria RP, Hansakul P, Thompson AM, Le-Petross H, Valero V, Bassett R, Huang ML, Santiago L, Adrada BE.

Am J Surg. 2018 Apr;215(4):693-698. doi: 10.1016/j.amjsurg.2017.06.032. Epub 2017 Jul 1.


Impact of Incredible Years® on teacher perceptions of parental involvement: A latent transition analysis.

Thompson AM, Herman KC, Stormont MA, Reinke WM, Webster-Stratton C.

J Sch Psychol. 2017 Jun;62:51-65. doi: 10.1016/j.jsp.2017.03.003. Epub 2017 Apr 9.


Family engagement in education and intervention: Implementation and evaluation to maximize family, school, and student outcomes.

Garbacz SA, Herman KC, Thompson AM, Reinke WM.

J Sch Psychol. 2017 Jun;62:1-10. doi: 10.1016/j.jsp.2017.04.002. Epub 2017 Apr 28. No abstract available.


Development of a Scalable Process for the Synthesis of DNDI-VL-2098: A Potential Preclinical Drug Candidate for the Treatment of Visceral Leishmaniasis.

Satam VS, Pedada SR, Kamaraj P, Antao N, Singh A, Hindupur RM, Pati HN, Thompson AM, Launay D, Martin D.

Org Process Res Dev. 2017 Jan 20;21(1):52-59. doi: 10.1021/acs.oprd.6b00331. Epub 2016 Dec 6. Review.


Interim heterogeneity changes measured using entropy texture features on T2-weighted MRI at 3.0 T are associated with pathological response to neoadjuvant chemotherapy in primary breast cancer.

Henderson S, Purdie C, Michie C, Evans A, Lerski R, Johnston M, Vinnicombe S, Thompson AM.

Eur Radiol. 2017 Nov;27(11):4602-4611. doi: 10.1007/s00330-017-4850-8. Epub 2017 May 18.


6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases.

Thompson AM, Blaser A, Palmer BD, Anderson RF, Shinde SS, Launay D, Chatelain E, Maes L, Franzblau SG, Wan B, Wang Y, Ma Z, Denny WA.

Bioorg Med Chem Lett. 2017 Jun 1;27(11):2583-2589. doi: 10.1016/j.bmcl.2017.03.069. Epub 2017 Mar 27.


7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis.

Thompson AM, O'Connor PD, Marshall AJ, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Franzblau SG, Wan B, Wang Y, Ma Z, Cooper CB, Denny WA.

J Med Chem. 2017 May 25;60(10):4212-4233. doi: 10.1021/acs.jmedchem.7b00034. Epub 2017 May 11.


Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32.

Lohmann AE, Liebman MF, Brien W, Parulekar WR, Gelmon KA, Shepherd LE, Ligibel JA, Hershman DL, Rastogi P, Mayer IA, Hobday TJ, Lemieux J, Thompson AM, Pritchard KI, Whelan TJ, Mukherjee SD, Chalchal HI, Bernstein V, Stambolic V, Chen BE, Goodwin PJ; From the CCTG, Alliance, SWOG, ECOG, NSABP Cooperative Groups.

Breast Cancer Res Treat. 2017 Jul;164(2):371-378. doi: 10.1007/s10549-017-4265-x. Epub 2017 Apr 26.


Efficacy and safety of twice- vs once-daily dosing of lisinopril for hypertension.

Tsai T, Kroehl ME, Smith SM, Thompson AM, Dai IY, Trinkley KE.

J Clin Hypertens (Greenwich). 2017 Sep;19(9):868-873. doi: 10.1111/jch.13011. Epub 2017 Apr 25.

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