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Items: 4

1.

Divergent Synthesis of Natural Derivatives of (+)-Saxitoxin Including 11-Saxitoxinethanoic Acid.

Walker JR, Merit JE, Thomas-Tran R, Tang DTY, Du Bois J.

Angew Chem Int Ed Engl. 2019 Feb 4;58(6):1689-1693. doi: 10.1002/anie.201811717. Epub 2019 Jan 2.

PMID:
30488599
2.

A selective class of inhibitors for the CLC-Ka chloride ion channel.

Koster AK, Wood CAP, Thomas-Tran R, Chavan TS, Almqvist J, Choi KH, Du Bois J, Maduke M.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4900-E4909. doi: 10.1073/pnas.1720584115. Epub 2018 Apr 18.

3.

Asymmetric synthesis of batrachotoxin: Enantiomeric toxins show functional divergence against NaV.

Logan MM, Toma T, Thomas-Tran R, Du Bois J.

Science. 2016 Nov 18;354(6314):865-869.

PMID:
27856903
4.

Mutant cycle analysis with modified saxitoxins reveals specific interactions critical to attaining high-affinity inhibition of hNaV1.7.

Thomas-Tran R, Du Bois J.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):5856-61. doi: 10.1073/pnas.1603486113. Epub 2016 May 9.

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