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Optimal Coherent Filtering for Single Noisy Photons.

Gao S, Lazo-Arjona O, Brecht B, Kaczmarek KT, Thomas SE, Nunn J, Ledingham PM, Saunders DJ, Walmsley IA.

Phys Rev Lett. 2019 Nov 22;123(21):213604. doi: 10.1103/PhysRevLett.123.213604.


Clinical myopathy in patients with nephropathic cystinosis.

Sadjadi R, Sullivan S, Grant N, Thomas SE, Doyle M, Hammond C, Duong R, Corre C, David W, Eichler F.

Muscle Nerve. 2019 Oct 6. doi: 10.1002/mus.26726. [Epub ahead of print]


Human GLB1 knockout cerebral organoids: A model system for testing AAV9-mediated GLB1 gene therapy for reducing GM1 ganglioside storage in GM1 gangliosidosis.

Latour YL, Yoon R, Thomas SE, Grant C, Li C, Sena-Esteves M, Allende ML, Proia RL, Tifft CJ.

Mol Genet Metab Rep. 2019 Sep 11;21:100513. doi: 10.1016/j.ymgmr.2019.100513. eCollection 2019 Dec.


Environmental Enrichment and Brain Neuroplasticity in the Kainate Rat Model of Temporal Lobe Epilepsy.

Gorantla VR, Thomas SE, Millis RM.

J Epilepsy Res. 2019 Jun 30;9(1):51-64. doi: 10.14581/jer.19006. eCollection 2019 Jun.


Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches.

Whitehouse AJ, Thomas SE, Brown KP, Fanourakis A, Chan DS, Libardo MDJ, Mendes V, Boshoff HIM, Floto RA, Abell C, Blundell TL, Coyne AG.

J Med Chem. 2019 Aug 8;62(15):7210-7232. doi: 10.1021/acs.jmedchem.9b00809. Epub 2019 Jul 19.


Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping.

Thomas SE, Collins P, James RH, Mendes V, Charoensutthivarakul S, Radoux C, Abell C, Coyne AG, Floto RA, von Delft F, Blundell TL.

Philos Trans A Math Phys Eng Sci. 2019 Jun 17;377(2147):20180422. doi: 10.1098/rsta.2018.0422.


A transient window of hypothyroidism alters neural progenitor cells and results in abnormal brain development.

O'Shaughnessy KL, Thomas SE, Spring SR, Ford JL, Ford RL, Gilbert ME.

Sci Rep. 2019 Mar 15;9(1):4662. doi: 10.1038/s41598-019-40249-7.


Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery.

Waman VP, Vedithi SC, Thomas SE, Bannerman BP, Munir A, Skwark MJ, Malhotra S, Blundell TL.

Emerg Microbes Infect. 2019;8(1):109-118. doi: 10.1080/22221751.2018.1561158. Review.


A Clinical Training Program for Hybrid Closed Loop Therapy in a Pediatric Diabetes Clinic.

Berget C, Thomas SE, Messer LH, Thivener K, Slover RH, Wadwa RP, Alonso GT.

J Diabetes Sci Technol. 2019 Mar 12:1932296819835183. doi: 10.1177/1932296819835183. [Epub ahead of print]


Arginine-deprivation-induced oxidative damage sterilizes Mycobacterium tuberculosis.

Tiwari S, van Tonder AJ, Vilchèze C, Mendes V, Thomas SE, Malek A, Chen B, Chen M, Kim J, Blundell TL, Parkhill J, Weinrick B, Berney M, Jacobs WR Jr.

Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):9779-9784. doi: 10.1073/pnas.1808874115. Epub 2018 Aug 24.


The Effects of Native Language and Gender on Procedure Performance.

Peres SC, Johnson WD, Thomas SE, Ritchey P.

Hum Factors. 2019 Feb;61(1):32-42. doi: 10.1177/0018720818793042. Epub 2018 Aug 24.


Comparative functional dynamics studies on the enzyme nano-bio interface.

Thomas SE, Comer J, Kim MJ, Marroquin S, Murthy V, Ramani M, Hopke TG, McCall J, Choi SO, DeLong RK.

Int J Nanomedicine. 2018 Aug 8;13:4523-4536. doi: 10.2147/IJN.S152222. eCollection 2018.



Thomas SE, Johnson EJ.

Adv Nutr. 2018 Mar 1;9(2):160-162. doi: 10.1093/advances/nmx005. Review. No abstract available.


Differences in the photoacclimation and photoprotection exhibited by two species of the ciguatera causing dinoflagellate genus, Gambierdiscus.

Leynse AK, Parsons ML, Thomas SE.

Harmful Algae. 2017 Dec;70:90-97. doi: 10.1016/j.hal.2017.10.008. Epub 2017 Nov 13.


Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew.

Thomas SE, Mendes V, Kim SY, Malhotra S, Ochoa-Montaño B, Blaszczyk M, Blundell TL.

J Mol Biol. 2017 Aug 18;429(17):2677-2693. doi: 10.1016/j.jmb.2017.06.014. Epub 2017 Jun 23. Review.


Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.

Chan DS, Mendes V, Thomas SE, McConnell BN, Matak-Vinković D, Coyne AG, Blundell TL, Abell C.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7488-7491. doi: 10.1002/anie.201702888. Epub 2017 May 31.


Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance.

Pandurangan AP, Ascher DB, Thomas SE, Blundell TL.

Biochem Soc Trans. 2017 Apr 15;45(2):303-311. doi: 10.1042/BST20160422. Review.


Structural insights into the EthR-DNA interaction using native mass spectrometry.

Shiu-Hin Chan D, Seetoh WG, McConnell BN, Matak-Vinković D, Thomas SE, Mendes V, Blaszczyk M, Coyne AG, Blundell TL, Abell C.

Chem Commun (Camb). 2017 Mar 23;53(25):3527-3530. doi: 10.1039/c7cc00804j.


Novel Biomarkers of Human GM1 Gangliosidosis Reflect the Clinical Efficacy of Gene Therapy in a Feline Model.

Gray-Edwards HL, Regier DS, Shirley JL, Randle AN, Salibi N, Thomas SE, Latour YL, Johnston J, Golas G, Maguire AS, Taylor AR, Sorjonen DC, McCurdy VJ, Christopherson PW, Bradbury AM, Beyers RJ, Johnson AK, Brunson BL, Cox NR, Baker HJ, Denney TS, Sena-Esteves M, Tifft CJ, Martin DR.

Mol Ther. 2017 Apr 5;25(4):892-903. doi: 10.1016/j.ymthe.2017.01.009. Epub 2017 Feb 22.


Structure-guided, target-based drug discovery - exploiting genome information from HIV to mycobacterial infections.

Malhotra S, Thomas SE, Ochoa Montano B, Blundell TL.

Postepy Biochem. 2016;62(3):262-272. Review.


Mechanisms of selective delivery of xanthophylls to retinal pigment epithelial cells by human lipoproteins.

Thomas SE, Harrison EH.

J Lipid Res. 2016 Oct;57(10):1865-1878. Epub 2016 Aug 18.


The role of azithromycin in healthcare-associated pneumonia treatment.

Thompson AM, Thomas SE, Schafers SJ, Hartmann AP, Call WB, Bushwitz J, Deal EN.

J Clin Pharm Ther. 2015 Oct;40(5):517-524. doi: 10.1111/jcpt.12319. Epub 2015 Aug 20. Review.


Improving Ethnocultural Empathy in Healthcare Students through a Targeted Intervention.

Fleming BD, Thomas SE, Burnham WS, Charles LT, Shaw D.

J Cult Divers. 2015 Summer;22(2):59-63.


Wound Dressings During Radiotherapy for Cancer: A Survey of Practice.

Thomas SE, Reimer-Kirkham S, Kohr R.

Clin J Oncol Nurs. 2015 Aug;19(4):E87-91. doi: 10.1188/15.CJON.E87-E91.


Safety and Efficacy of Botulinum Toxin A in Children Undergoing Lower Limb Lengthening and Deformity Correction: Results of a Double-blind, Multicenter, Randomized Controlled Trial.

Hamdy RC, Montpetit K, Aiona MD, MacKenzie WG, van Bosse HJ, Narayanan U, Raney EM, Chafetz RS, Thomas SE, Weir S, Gregory S, Yorgova P, Takahashi S, Rinaldi M, Zhang X, Dahan-Oliel N.

J Pediatr Orthop. 2016 Jan;36(1):48-55. doi: 10.1097/BPO.0000000000000398.


The clinical psychologist and the management of inpatient pain: a small case series.

Childs SR, Casely EM, Kuehler BM, Ward S, Halmshaw CL, Thomas SE, Goodall ID, Bantel C.

Neuropsychiatr Dis Treat. 2014 Dec 2;10:2291-7. doi: 10.2147/NDT.S70555. eCollection 2014.


A district general hospital experience of palliative biliary stenting.

Thomas SE, Lee MJ, Sivaramakrishnan N, Lambert K.

BMJ Support Palliat Care. 2015 Sep;5(3):297-300. doi: 10.1136/bmjspcare-2014-000752. Epub 2014 Dec 9.


Sisters unbound is required for meiotic centromeric cohesion in Drosophila melanogaster.

Krishnan B, Thomas SE, Yan R, Yamada H, Zhulin IB, McKee BD.

Genetics. 2014 Nov;198(3):947-65. doi: 10.1534/genetics.114.166009. Epub 2014 Sep 5.


Late-onset schizophrenia: do recent studies support categorizing LOS as a subtype of schizophrenia?

Maglione JE, Thomas SE, Jeste DV.

Curr Opin Psychiatry. 2014 May;27(3):173-8. doi: 10.1097/YCO.0000000000000049. Review.


Coping motives for drinking affect stress reactivity but not alcohol consumption in a clinical laboratory setting.

Thomas SE, Merrill JE, von Hofe J, Magid V.

J Stud Alcohol Drugs. 2014 Jan;75(1):115-23.


An online alcohol and oral health curriculum for dental students.

Miller PM, Ravenel MC, Mauldin MP, Sulkowski S, Lowndes A, Thomas SE.

J Dent Educ. 2014 Jan;78(1):16-23.


Women with epilepsy and infertility have different reproductive hormone profile than others.

Thomas SV, Sarma PS, Nirmala C, Mathai A, Thomas SE, Thomas AC.

Ann Indian Acad Neurol. 2013 Oct;16(4):544-8. doi: 10.4103/0972-2327.120460.


GnRH receptor antagonists for prostate cancer.

Patrick E, Whitson M, Smith A, Parnell J, Thomas SE, Blankenship CC.

JAAPA. 2013 Jul;26(7):51-2. Review.


Sterol metabolism regulates neuroserpin polymer degradation in the absence of the unfolded protein response in the dementia FENIB.

Roussel BD, Newton TM, Malzer E, Simecek N, Haq I, Thomas SE, Burr ML, Lehner PJ, Crowther DC, Marciniak SJ, Lomas DA.

Hum Mol Genet. 2013 Nov 15;22(22):4616-26. doi: 10.1093/hmg/ddt310. Epub 2013 Jun 28.


A confirmed case of injury to the long thoracic nerve following a posterior approach to an interscalene nerve block.

Thomas SE, Winchester JB, Hickman G, DeBusk E.

Reg Anesth Pain Med. 2013 Jul-Aug;38(4):370. doi: 10.1097/AAP.0b013e3182905b98. No abstract available.


Treating individuals with social anxiety disorder and at-risk drinking: phasing in a brief alcohol intervention following paroxetine.

Book SW, Thomas SE, Smith JP, Randall PK, Kushner MG, Bernstein GA, Specker SM, Miller PM, Randall CL.

J Anxiety Disord. 2013 Mar;27(2):252-8. doi: 10.1016/j.janxdis.2013.02.008. Epub 2013 Mar 4.


Coordinate regulation of eIF2α phosphorylation by PPP1R15 and GCN2 is required during Drosophila development.

Malzer E, Szajewska-Skuta M, Dalton LE, Thomas SE, Hu N, Skaer H, Lomas DA, Crowther DC, Marciniak SJ.

J Cell Sci. 2013 Mar 15;126(Pt 6):1406-15. doi: 10.1242/jcs.117614. Epub 2013 Feb 15.


p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress.

Thomas SE, Malzer E, Ordóñez A, Dalton LE, van 't Wout EF, Liniker E, Crowther DC, Lomas DA, Marciniak SJ.

J Biol Chem. 2013 Mar 15;288(11):7606-17. doi: 10.1074/jbc.M112.424655. Epub 2013 Jan 22.


Interactions between adaptive coping and drinking to cope in predicting naturalistic drinking and drinking following a lab-based psychosocial stressor.

Merrill JE, Thomas SE.

Addict Behav. 2013 Mar;38(3):1672-8. doi: 10.1016/j.addbeh.2012.10.003. Epub 2012 Oct 8.


Severity of anxiety in mental health versus addiction treatment settings when social anxiety and substance abuse are comorbid.

Book SW, Thomas SE, Smith JP, Miller PM.

Addict Behav. 2012 Oct;37(10):1158-61. doi: 10.1016/j.addbeh.2012.04.016. Epub 2012 May 7.


Client attitudes toward alcohol use self-report.

Book SW, Thomas SE, Stewart SH, Miller PM.

Subst Abus. 2012;33(2):124-9. doi: 10.1080/00221341.2011.630941.


Physician assistant program characteristics and faculty credentials on physician assistant national certifying exam pass rates.

Bushardt RL, Booze LE, Hewett ML, Hildebrandt C, Thomas SE.

J Physician Assist Educ. 2012;23(1):19-23.


The serpinopathies studying serpin polymerization in vivo.

Irving JA, Ekeowa UI, Belorgey D, Haq I, Gooptu B, Miranda E, Pérez J, Roussel BD, Ordóñez A, Dalton LE, Thomas SE, Marciniak SJ, Parfrey H, Chilvers ER, Teckman JH, Alam S, Mahadeva R, Rashid ST, Vallier L, Lomas DA.

Methods Enzymol. 2011;501:421-66. doi: 10.1016/B978-0-12-385950-1.00018-3.


Unravelling the story of protein misfolding in diabetes mellitus.

Thomas SE, Dalton L, Malzer E, Marciniak SJ.

World J Diabetes. 2011 Jul 15;2(7):114-8. doi: 10.4239/wjd.v2.i7.114.


Developing a program to promote stress resilience and self-care in first-year medical students.

Thomas SE, Haney MK, Pelic CM, Shaw D, Wong JG.

Can Med Educ J. 2011;2(1):e32-e36.


An acute psychosocial stressor increases drinking in non-treatment-seeking alcoholics.

Thomas SE, Bacon AK, Randall PK, Brady KT, See RE.

Psychopharmacology (Berl). 2011 Nov;218(1):19-28. doi: 10.1007/s00213-010-2163-6. Epub 2011 Jan 28.


Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation.

Liu B, Moloney A, Meehan S, Morris K, Thomas SE, Serpell LC, Hider R, Marciniak SJ, Lomas DA, Crowther DC.

J Biol Chem. 2011 Feb 11;286(6):4248-56. doi: 10.1074/jbc.M110.158980. Epub 2010 Dec 8.


An acute psychosocial stressor does not potentiate alcohol cue reactivity in non-treatment-seeking alcoholics.

Thomas SE, Randall PK, Brady K, See RE, Drobes DJ.

Alcohol Clin Exp Res. 2011 Mar;35(3):464-73. doi: 10.1111/j.1530-0277.2010.01363.x. Epub 2010 Dec 8.


Diabetes as a disease of endoplasmic reticulum stress.

Thomas SE, Dalton LE, Daly ML, Malzer E, Marciniak SJ.

Diabetes Metab Res Rev. 2010 Nov;26(8):611-21. doi: 10.1002/dmrr.1132. Epub 2010 Oct 3. Review.


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