Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 236


ZBP1/DAI-Dependent Cell Death Pathways in Influenza A Virus Immunity and Pathogenesis.

Thomas PG, Shubina M, Balachandran S.

Curr Top Microbiol Immunol. 2020 Jan 23. doi: 10.1007/82_2019_190. [Epub ahead of print]


Human Susceptibility to Influenza Infection and Severe Disease.

Mettelman RC, Thomas PG.

Cold Spring Harb Perspect Med. 2020 Jan 21. pii: a038711. doi: 10.1101/cshperspect.a038711. [Epub ahead of print]


Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer.

Newman JH, Chesson CB, Herzog NL, Bommareddy PK, Aspromonte SM, Pepe R, Estupinian R, Aboelatta MM, Buddhadev S, Tarabichi S, Lee M, Li S, Medina DJ, Giurini EF, Gupta KH, Guevara-Aleman G, Rossi M, Nowicki C, Abed A, Goldufsky JW, Broucek JR, Redondo RE, Rotter D, Jhawar SR, Wang SJ, Kohlhapp FJ, Kaufman HL, Thomas PG, Gupta V, Kuzel TM, Reiser J, Paras J, Kane MP, Singer EA, Malhotra J, Denzin LK, Sant'Angelo DB, Rabson AB, Lee LY, Lasfar A, Langenfeld J, Schenkel JM, Fidler MJ, Ruiz ES, Marzo AL, Rudra JS, Silk AW, Zloza A.

Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1119-1128. doi: 10.1073/pnas.1904022116. Epub 2019 Dec 30.


Simulation modelling for immunologists.

Handel A, La Gruta NL, Thomas PG.

Nat Rev Immunol. 2019 Dec 5. doi: 10.1038/s41577-019-0235-3. [Epub ahead of print] Review.


Emergency Trauma Providers as Equal Partners: From "Proof of Concept" to "Outcome Parity".

Kelley KC, Alers A, Bendas C, Thomas PG, Cipolla J, Hoey BA, Hoff WS, Wilde-Onia R, Weber H, Stawicki SP.

Am Surg. 2019 Sep 1;85(9):961-964.


Human γδ T-cell receptor repertoire is shaped by influenza viruses, age and tissue compartmentalisation.

Sant S, Jenkins MR, Dash P, Watson KA, Wang Z, Pizzolla A, Koutsakos M, Nguyen TH, Lappas M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Kotsimbos TC, Cheng AC, Wakim L, Doherty PC, Thomas PG, Loh L, Kedzierska K.

Clin Transl Immunology. 2019 Sep 23;8(9):e1079. doi: 10.1002/cti2.1079. eCollection 2019.


Treatment response and outcome of children with T-cell acute lymphoblastic leukemia expressing the gamma-delta T-cell receptor.

Pui CH, Pei D, Cheng C, Tomchuck SL, Evans SN, Inaba H, Jeha S, Raimondi SC, Choi JK, Thomas PG, Dallas MH.

Oncoimmunology. 2019 May 17;8(8):1599637. doi: 10.1080/2162402X.2019.1599637. eCollection 2019.


Influenza virus-related critical illness: pathophysiology and epidemiology.

Kalil AC, Thomas PG.

Crit Care. 2019 Jul 19;23(1):258. doi: 10.1186/s13054-019-2539-x. Review.


A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls.

Cohen L, Fiore-Gartland A, Randolph AG, Panoskaltsis-Mortari A, Wong SS, Ralston J, Wood T, Seeds R, Huang QS, Webby RJ, Thomas PG, Hertz T.

Front Immunol. 2019 Jun 18;10:1338. doi: 10.3389/fimmu.2019.01338. eCollection 2019.


Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses.

Wu T, Guan J, Handel A, Tscharke DC, Sidney J, Sette A, Wakim LM, Sng XYX, Thomas PG, Croft NP, Purcell AW, La Gruta NL.

Nat Commun. 2019 Jun 28;10(1):2846. doi: 10.1038/s41467-019-10661-8.


Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.

Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG.

Sci Transl Med. 2019 Jun 26;11(498). pii: eaat8549. doi: 10.1126/scitranslmed.aat8549.


Elements of a successful hospital-based deceased donation programme in India: Zero to eighty-five in two years.

Thomas PG, Aswathy C, Joshy G, Mathew J.

Natl Med J India. 2018 Jul-Aug;31(4):201-205. doi: 10.4103/0970-258X.258217.


The expanding role of systems immunology in decoding the T cell receptor repertoire.

Venturi V, Thomas PG.

Curr Opin Syst Biol. 2018 Dec;12:37-45. doi: 10.1016/j.coisb.2018.09.005. Epub 2018 Sep 14.


Combination Therapy Targeting Platelet Activation and Virus Replication Protects Mice against Lethal Influenza Pneumonia.

Pulavendran S, Rudd JM, Maram P, Thomas PG, Akhilesh R, Malayer JR, Chow VTK, Teluguakula N.

Am J Respir Cell Mol Biol. 2019 Dec;61(6):689-701. doi: 10.1165/rcmb.2018-0196OC.


Bach2 Negatively Regulates T Follicular Helper Cell Differentiation and Is Critical for CD4+ T Cell Memory.

Geng J, Wei H, Shi B, Wang YH, Greer BD, Pittman M, Smith E, Thomas PG, Kutsch O, Hu H.

J Immunol. 2019 May 15;202(10):2991-2998. doi: 10.4049/jimmunol.1801626. Epub 2019 Apr 10.


Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells.

Bakke J, Wright WC, Zamora AE, Oladimeji P, Crawford JC, Brewer CT, Autry RJ, Evans WE, Thomas PG, Chen T.

BMC Cancer. 2019 Mar 21;19(1):253. doi: 10.1186/s12885-019-5455-1.


Human CD8+ T cell cross-reactivity across influenza A, B and C viruses.

Koutsakos M, Illing PT, Nguyen THO, Mifsud NA, Crawford JC, Rizzetto S, Eltahla AA, Clemens EB, Sant S, Chua BY, Wong CY, Allen EK, Teng D, Dash P, Boyd DF, Grzelak L, Zeng W, Hurt AC, Barr I, Rockman S, Jackson DC, Kotsimbos TC, Cheng AC, Richards M, Westall GP, Loudovaris T, Mannering SI, Elliott M, Tangye SG, Wakim LM, Rossjohn J, Vijaykrishna D, Luciani F, Thomas PG, Gras S, Purcell AW, Kedzierska K.

Nat Immunol. 2019 May;20(5):613-625. doi: 10.1038/s41590-019-0320-6. Epub 2019 Feb 18.


Using T Cell Receptor Repertoires to Understand the Principles of Adaptive Immune Recognition.

Bradley P, Thomas PG.

Annu Rev Immunol. 2019 Apr 26;37:547-570. doi: 10.1146/annurev-immunol-042718-041757. Epub 2019 Jan 30.


Activity of enisamium, an isonicotinic acid derivative, against influenza viruses in differentiated normal human bronchial epithelial cells.

Boltz D, Peng X, Muzzio M, Dash P, Thomas PG, Margitich V.

Antivir Chem Chemother. 2018 Jan-Dec;26:2040206618811416. doi: 10.1177/2040206618811416.


Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity.

Guo XJ, Dash P, Crawford JC, Allen EK, Zamora AE, Boyd DF, Duan S, Bajracharya R, Awad WA, Apiwattanakul N, Vogel P, Kanneganti TD, Thomas PG.

Immunity. 2018 Sep 18;49(3):531-544.e6. doi: 10.1016/j.immuni.2018.07.011. Epub 2018 Aug 28.


Altered CD4+ T cell immunity in nurses occupationally exposed to viral pathogens.

Elias G, Souquette A, Heynderickx S, De Meester I, Jansens H, Beutels P, Van Damme P, Smits E, Thomas PG, Van Tendeloo V, Ogunjimi B.

Clin Exp Immunol. 2018 Nov;194(2):192-204. doi: 10.1111/cei.13193. Epub 2018 Sep 19.


Moving Forward: Recent Developments for the Ferret Biomedical Research Model.

Albrecht RA, Liu WC, Sant AJ, Tompkins SM, Pekosz A, Meliopoulos V, Cherry S, Thomas PG, Schultz-Cherry S.

mBio. 2018 Jul 17;9(4). pii: e01113-18. doi: 10.1128/mBio.01113-18. Review.


Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

Sant S, Grzelak L, Wang Z, Pizzolla A, Koutsakos M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Wakim LM, Rossjohn J, Gras S, Richards M, Xu J, Thomas PG, Loh L, Nguyen THO, Kedzierska K.

Front Immunol. 2018 Jun 27;9:1453. doi: 10.3389/fimmu.2018.01453. eCollection 2018.


MELD-based organ allocation policy: Time for change.

Thomas PG.

Am J Transplant. 2018 Nov;18(11):2833. doi: 10.1111/ajt.15010. Epub 2018 Aug 28. No abstract available.


Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells.

Yang K, Blanco DB, Chen X, Dash P, Neale G, Rosencrance C, Easton J, Chen W, Cheng C, Dhungana Y, Kc A, Awad W, Guo XJ, Thomas PG, Chi H.

Sci Immunol. 2018 Jul 6;3(25). pii: eaas9818. doi: 10.1126/sciimmunol.aas9818.


Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells.

Keating R, Morris MY, Yue W, Reynolds CE, Harris TL, Brown SA, Doherty PC, Thomas PG, McGargill MA.

Immunol Cell Biol. 2018 Nov;96(10):1104-1119. doi: 10.1111/imcb.12189. Epub 2018 Aug 10.


Evidence-based approach to the trauma patient in extremis: Transitioning from exclusive emergency department thoracotomy use to protocolized approaches incorporating resuscitative endovascular balloon occlusion of the aorta.

Spalding MC, Thomas PG, O'Mara MS, Ramirez CL, Yanagawa FS, Hon HH, Hoey BA, Hoff WS, Cipolla J, Stawicki SP.

Int J Crit Illn Inj Sci. 2018 Apr-Jun;8(2):57-62. doi: 10.4103/IJCIIS.IJCIIS_28_18. No abstract available.


Bohemian T cell receptors: sketching the repertoires of unconventional lymphocytes.

Schattgen SA, Thomas PG.

Immunol Rev. 2018 Jul;284(1):79-90. doi: 10.1111/imr.12668. Review.


Past Life and Future Effects-How Heterologous Infections Alter Immunity to Influenza Viruses.

Souquette A, Thomas PG.

Front Immunol. 2018 May 22;9:1071. doi: 10.3389/fimmu.2018.01071. eCollection 2018. Review.


Understanding the drivers of MHC restriction of T cell receptors.

La Gruta NL, Gras S, Daley SR, Thomas PG, Rossjohn J.

Nat Rev Immunol. 2018 Jul;18(7):467-478. doi: 10.1038/s41577-018-0007-5. Review.


The TNF Superfamily Molecule LIGHT Promotes the Generation of Circulating and Lung-Resident Memory CD8 T Cells following an Acute Respiratory Virus Infection.

Desai P, Tahiliani V, Hutchinson TE, Dastmalchi F, Stanfield J, Abboud G, Thomas PG, Ware CF, Song J, Croft M, Salek-Ardakani S.

J Immunol. 2018 Apr 15;200(8):2894-2904. doi: 10.4049/jimmunol.1701499. Epub 2018 Mar 7.


Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease.

Wang Z, Zhu L, Nguyen THO, Wan Y, Sant S, Quiñones-Parra SM, Crawford JC, Eltahla AA, Rizzetto S, Bull RA, Qiu C, Koutsakos M, Clemens EB, Loh L, Chen T, Liu L, Cao P, Ren Y, Kedzierski L, Kotsimbos T, McCaw JM, La Gruta NL, Turner SJ, Cheng AC, Luciani F, Zhang X, Doherty PC, Thomas PG, Xu J, Kedzierska K.

Nat Commun. 2018 Feb 26;9(1):824. doi: 10.1038/s41467-018-03243-7.


A seven-center examination of the relationship between monthly volume and mortality in trauma: a hypothesis-generating study.

Stawicki SP, Habeeb K, Martin ND, O'Mara MS, Cipolla J, Evans DC, Boulger C, Sarani B, Cook CH, Gupta A, Hoff WS, Thomas PG, Jordan JM, Guo WA, Seamon MJ.

Eur J Trauma Emerg Surg. 2019 Apr;45(2):281-288. doi: 10.1007/s00068-018-0904-0. Epub 2018 Jan 12.


Hitting the Target: How T Cells Detect and Eliminate Tumors.

Zamora AE, Crawford JC, Thomas PG.

J Immunol. 2018 Jan 15;200(2):392-399. doi: 10.4049/jimmunol.1701413. Review.


Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.

Pizzolla A, Nguyen TH, Sant S, Jaffar J, Loudovaris T, Mannering SI, Thomas PG, Westall GP, Kedzierska K, Wakim LM.

J Clin Invest. 2018 Feb 1;128(2):721-733. doi: 10.1172/JCI96957. Epub 2018 Jan 8.


Cytokine Profiles of Severe Influenza Virus-Related Complications in Children.

Fiore-Gartland A, Panoskaltsis-Mortari A, Agan AA, Mistry AJ, Thomas PG, Matthay MA; PALISI PICFlu Investigators, Hertz T, Randolph AG.

Front Immunol. 2017 Nov 6;8:1423. doi: 10.3389/fimmu.2017.01423. eCollection 2017.


Severe Influenza Is Characterized by Prolonged Immune Activation: Results From the SHIVERS Cohort Study.

Wong SS, Oshansky CM, Guo XJ, Ralston J, Wood T, Seeds R, Newbern C, Waite B, Reynolds G, Widdowson MA, Huang QS, Webby RJ, Thomas PG; SHIVERS Investigation Team.

J Infect Dis. 2018 Jan 4;217(2):245-256. doi: 10.1093/infdis/jix571.


The Role of Extracellular Histones in Influenza Virus Pathogenesis.

Ashar HK, Mueller NC, Rudd JM, Snider TA, Achanta M, Prasanthi M, Pulavendran S, Thomas PG, Ramachandran A, Malayer JR, Ritchey JW, Rajasekhar R, Chow VTK, Esmon CT, Teluguakula N.

Am J Pathol. 2018 Jan;188(1):135-148. doi: 10.1016/j.ajpath.2017.09.014. Epub 2017 Oct 26.


VDJdb: a curated database of T-cell receptor sequences with known antigen specificity.

Shugay M, Bagaev DV, Zvyagin IV, Vroomans RM, Crawford JC, Dolton G, Komech EA, Sycheva AL, Koneva AE, Egorov ES, Eliseev AV, Van Dyk E, Dash P, Attaf M, Rius C, Ladell K, McLaren JE, Matthews KK, Clemens EB, Douek DC, Luciani F, van Baarle D, Kedzierska K, Kesmir C, Thomas PG, Price DA, Sewell AK, Chudakov DM.

Nucleic Acids Res. 2018 Jan 4;46(D1):D419-D427. doi: 10.1093/nar/gkx760.


HVEM Imprints Memory Potential on Effector CD8 T Cells Required for Protective Mucosal Immunity.

Desai P, Abboud G, Stanfield J, Thomas PG, Song J, Ware CF, Croft M, Salek-Ardakani S.

J Immunol. 2017 Oct 15;199(8):2968-2975. doi: 10.4049/jimmunol.1700959. Epub 2017 Sep 1.


The neoepitope landscape in pediatric cancers.

Chang TC, Carter RA, Li Y, Li Y, Wang H, Edmonson MN, Chen X, Arnold P, Geiger TL, Wu G, Peng J, Dyer M, Downing JR, Green DR, Thomas PG, Zhang J.

Genome Med. 2017 Aug 31;9(1):78. doi: 10.1186/s13073-017-0468-3.


Transcription factor ZNF148 is a negative regulator of human muscle differentiation.

Bakke J, Wright WC, Zamora AE, Ong SS, Wang YM, Hoyer JD, Brewer CT, Thomas PG, Chen T.

Sci Rep. 2017 Aug 15;7(1):8138. doi: 10.1038/s41598-017-08267-5.


SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans.

Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG.

Nat Med. 2017 Aug;23(8):975-983. doi: 10.1038/nm.4370. Epub 2017 Jul 17.


Keys to successful organ procurement: An experience-based review of clinical practices at a high-performing health-care organization.

Wojda TR, Stawicki SP, Yandle KP, Bleil M, Axelband J, Wilde-Onia R, Thomas PG, Cipolla J, Hoff WS, Shultz J.

Int J Crit Illn Inj Sci. 2017 Apr-Jun;7(2):91-100. doi: 10.4103/IJCIIS.IJCIIS_30_17. Review.


De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Ghoneim HE, Fan Y, Moustaki A, Abdelsamed HA, Dash P, Dogra P, Carter R, Awad W, Neale G, Thomas PG, Youngblood B.

Cell. 2017 Jun 29;170(1):142-157.e19. doi: 10.1016/j.cell.2017.06.007. Epub 2017 Jun 22.


A constant companion: immune recognition and response to cytomegalovirus with aging and implications for immune fitness.

Souquette A, Frere J, Smithey M, Sauce D, Thomas PG.

Geroscience. 2017 Jun;39(3):293-303. doi: 10.1007/s11357-017-9982-x. Epub 2017 Jun 24. Review.


Quantifiable predictive features define epitope-specific T cell receptor repertoires.

Dash P, Fiore-Gartland AJ, Hertz T, Wang GC, Sharma S, Souquette A, Crawford JC, Clemens EB, Nguyen THO, Kedzierska K, La Gruta NL, Bradley P, Thomas PG.

Nature. 2017 Jul 6;547(7661):89-93. doi: 10.1038/nature22383. Epub 2017 Jun 21.


New fronts emerge in the influenza cytokine storm.

Guo XJ, Thomas PG.

Semin Immunopathol. 2017 Jul;39(5):541-550. doi: 10.1007/s00281-017-0636-y. Epub 2017 May 29. Review.


Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention.

Smallwood HS, Duan S, Morfouace M, Rezinciuc S, Shulkin BL, Shelat A, Zink EE, Milasta S, Bajracharya R, Oluwaseum AJ, Roussel MF, Green DR, Pasa-Tolic L, Thomas PG.

Cell Rep. 2017 May 23;19(8):1640-1653. doi: 10.1016/j.celrep.2017.04.039.


Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.

Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators.

J Infect Dis. 2017 Jul 1;216(1):14-21. doi: 10.1093/infdis/jix242.

Supplemental Content

Loading ...
Support Center