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Items: 1 to 50 of 214

1.

Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection.

Sant S, Grzelak L, Wang Z, Pizzolla A, Koutsakos M, Crowe J, Loudovaris T, Mannering SI, Westall GP, Wakim LM, Rossjohn J, Gras S, Richards M, Xu J, Thomas PG, Loh L, Nguyen THO, Kedzierska K.

Front Immunol. 2018 Jun 27;9:1453. doi: 10.3389/fimmu.2018.01453. eCollection 2018.

PMID:
29997621
2.

MELD based organ allocation policy : Time for change.

Thomas PG.

Am J Transplant. 2018 Jul 7. doi: 10.1111/ajt.15010. [Epub ahead of print]

PMID:
29981202
3.

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells.

Yang K, Blanco DB, Chen X, Dash P, Neale G, Rosencrance C, Easton J, Chen W, Cheng C, Dhungana Y, Kc A, Awad W, Guo XJ, Thomas PG, Chi H.

Sci Immunol. 2018 Jul 6;3(25). pii: eaas9818. doi: 10.1126/sciimmunol.aas9818.

PMID:
29980617
4.

Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells.

Keating R, Morris MY, Yue W, Reynolds CE, Harris TL, Brown SA, Doherty PC, Thomas PG, McGargill MA.

Immunol Cell Biol. 2018 Jul 4. doi: 10.1111/imcb.12189. [Epub ahead of print]

PMID:
29972699
5.

Evidence-based approach to the trauma patient in extremis: Transitioning from exclusive emergency department thoracotomy use to protocolized approaches incorporating resuscitative endovascular balloon occlusion of the aorta.

Spalding MC, Thomas PG, O'Mara MS, Ramirez CL, Yanagawa FS, Hon HH, Hoey BA, Hoff WS, Cipolla J, Stawicki SP.

Int J Crit Illn Inj Sci. 2018 Apr-Jun;8(2):57-62. doi: 10.4103/IJCIIS.IJCIIS_28_18. No abstract available.

6.

Bohemian T cell receptors: sketching the repertoires of unconventional lymphocytes.

Schattgen SA, Thomas PG.

Immunol Rev. 2018 Jul;284(1):79-90. doi: 10.1111/imr.12668.

PMID:
29944761
7.

Past Life and Future Effects-How Heterologous Infections Alter Immunity to Influenza Viruses.

Souquette A, Thomas PG.

Front Immunol. 2018 May 22;9:1071. doi: 10.3389/fimmu.2018.01071. eCollection 2018. Review.

8.

Understanding the drivers of MHC restriction of T cell receptors.

La Gruta NL, Gras S, Daley SR, Thomas PG, Rossjohn J.

Nat Rev Immunol. 2018 Jul;18(7):467-478. doi: 10.1038/s41577-018-0007-5. Review.

PMID:
29636542
9.

The TNF Superfamily Molecule LIGHT Promotes the Generation of Circulating and Lung-Resident Memory CD8 T Cells following an Acute Respiratory Virus Infection.

Desai P, Tahiliani V, Hutchinson TE, Dastmalchi F, Stanfield J, Abboud G, Thomas PG, Ware CF, Song J, Croft M, Salek-Ardakani S.

J Immunol. 2018 Apr 15;200(8):2894-2904. doi: 10.4049/jimmunol.1701499. Epub 2018 Mar 7.

PMID:
29514949
10.

Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease.

Wang Z, Zhu L, Nguyen THO, Wan Y, Sant S, Quiñones-Parra SM, Crawford JC, Eltahla AA, Rizzetto S, Bull RA, Qiu C, Koutsakos M, Clemens EB, Loh L, Chen T, Liu L, Cao P, Ren Y, Kedzierski L, Kotsimbos T, McCaw JM, La Gruta NL, Turner SJ, Cheng AC, Luciani F, Zhang X, Doherty PC, Thomas PG, Xu J, Kedzierska K.

Nat Commun. 2018 Feb 26;9(1):824. doi: 10.1038/s41467-018-03243-7.

11.

A seven-center examination of the relationship between monthly volume and mortality in trauma: a hypothesis-generating study.

Stawicki SP, Habeeb K, Martin ND, O'Mara MS, Cipolla J, Evans DC, Boulger C, Sarani B, Cook CH, Gupta A, Hoff WS, Thomas PG, Jordan JM, Guo WA, Seamon MJ.

Eur J Trauma Emerg Surg. 2018 Jan 12. doi: 10.1007/s00068-018-0904-0. [Epub ahead of print]

PMID:
29330633
12.

Hitting the Target: How T Cells Detect and Eliminate Tumors.

Zamora AE, Crawford JC, Thomas PG.

J Immunol. 2018 Jan 15;200(2):392-399. doi: 10.4049/jimmunol.1701413. Review.

PMID:
29311380
13.

Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.

Pizzolla A, Nguyen TH, Sant S, Jaffar J, Loudovaris T, Mannering SI, Thomas PG, Westall GP, Kedzierska K, Wakim LM.

J Clin Invest. 2018 Feb 1;128(2):721-733. doi: 10.1172/JCI96957. Epub 2018 Jan 8.

14.

Cytokine Profiles of Severe Influenza Virus-Related Complications in Children.

Fiore-Gartland A, Panoskaltsis-Mortari A, Agan AA, Mistry AJ, Thomas PG, Matthay MA; PALISI PICFlu Investigators, Hertz T, Randolph AG.

Front Immunol. 2017 Nov 6;8:1423. doi: 10.3389/fimmu.2017.01423. eCollection 2017.

15.

Severe Influenza Is Characterized by Prolonged Immune Activation: Results From the SHIVERS Cohort Study.

Wong SS, Oshansky CM, Guo XJ, Ralston J, Wood T, Seeds R, Newbern C, Waite B, Reynolds G, Widdowson MA, Huang QS, Webby RJ, Thomas PG; SHIVERS Investigation Team .

J Infect Dis. 2018 Jan 4;217(2):245-256. doi: 10.1093/infdis/jix571.

PMID:
29112724
16.

The Role of Extracellular Histones in Influenza Virus Pathogenesis.

Ashar HK, Mueller NC, Rudd JM, Snider TA, Achanta M, Prasanthi M, Pulavendran S, Thomas PG, Ramachandran A, Malayer JR, Ritchey JW, Rajasekhar R, Chow VTK, Esmon CT, Teluguakula N.

Am J Pathol. 2018 Jan;188(1):135-148. doi: 10.1016/j.ajpath.2017.09.014. Epub 2017 Oct 26.

PMID:
29107075
17.

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity.

Shugay M, Bagaev DV, Zvyagin IV, Vroomans RM, Crawford JC, Dolton G, Komech EA, Sycheva AL, Koneva AE, Egorov ES, Eliseev AV, Van Dyk E, Dash P, Attaf M, Rius C, Ladell K, McLaren JE, Matthews KK, Clemens EB, Douek DC, Luciani F, van Baarle D, Kedzierska K, Kesmir C, Thomas PG, Price DA, Sewell AK, Chudakov DM.

Nucleic Acids Res. 2018 Jan 4;46(D1):D419-D427. doi: 10.1093/nar/gkx760.

18.

HVEM Imprints Memory Potential on Effector CD8 T Cells Required for Protective Mucosal Immunity.

Desai P, Abboud G, Stanfield J, Thomas PG, Song J, Ware CF, Croft M, Salek-Ardakani S.

J Immunol. 2017 Oct 15;199(8):2968-2975. doi: 10.4049/jimmunol.1700959. Epub 2017 Sep 1.

PMID:
28864473
19.

The neoepitope landscape in pediatric cancers.

Chang TC, Carter RA, Li Y, Li Y, Wang H, Edmonson MN, Chen X, Arnold P, Geiger TL, Wu G, Peng J, Dyer M, Downing JR, Green DR, Thomas PG, Zhang J.

Genome Med. 2017 Aug 31;9(1):78. doi: 10.1186/s13073-017-0468-3.

20.

Transcription factor ZNF148 is a negative regulator of human muscle differentiation.

Bakke J, Wright WC, Zamora AE, Ong SS, Wang YM, Hoyer JD, Brewer CT, Thomas PG, Chen T.

Sci Rep. 2017 Aug 15;7(1):8138. doi: 10.1038/s41598-017-08267-5.

21.

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans.

Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG.

Nat Med. 2017 Aug;23(8):975-983. doi: 10.1038/nm.4370. Epub 2017 Jul 17.

PMID:
28714988
22.

Keys to successful organ procurement: An experience-based review of clinical practices at a high-performing health-care organization.

Wojda TR, Stawicki SP, Yandle KP, Bleil M, Axelband J, Wilde-Onia R, Thomas PG, Cipolla J, Hoff WS, Shultz J.

Int J Crit Illn Inj Sci. 2017 Apr-Jun;7(2):91-100. doi: 10.4103/IJCIIS.IJCIIS_30_17. Review.

23.

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.

Ghoneim HE, Fan Y, Moustaki A, Abdelsamed HA, Dash P, Dogra P, Carter R, Awad W, Neale G, Thomas PG, Youngblood B.

Cell. 2017 Jun 29;170(1):142-157.e19. doi: 10.1016/j.cell.2017.06.007. Epub 2017 Jun 22.

24.

A constant companion: immune recognition and response to cytomegalovirus with aging and implications for immune fitness.

Souquette A, Frere J, Smithey M, Sauce D, Thomas PG.

Geroscience. 2017 Jun;39(3):293-303. doi: 10.1007/s11357-017-9982-x. Epub 2017 Jun 24. Review.

25.

Quantifiable predictive features define epitope-specific T cell receptor repertoires.

Dash P, Fiore-Gartland AJ, Hertz T, Wang GC, Sharma S, Souquette A, Crawford JC, Clemens EB, Nguyen THO, Kedzierska K, La Gruta NL, Bradley P, Thomas PG.

Nature. 2017 Jul 6;547(7661):89-93. doi: 10.1038/nature22383. Epub 2017 Jun 21.

26.

New fronts emerge in the influenza cytokine storm.

Guo XJ, Thomas PG.

Semin Immunopathol. 2017 Jul;39(5):541-550. doi: 10.1007/s00281-017-0636-y. Epub 2017 May 29. Review.

27.

Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention.

Smallwood HS, Duan S, Morfouace M, Rezinciuc S, Shulkin BL, Shelat A, Zink EE, Milasta S, Bajracharya R, Oluwaseum AJ, Roussel MF, Green DR, Pasa-Tolic L, Thomas PG.

Cell Rep. 2017 May 23;19(8):1640-1653. doi: 10.1016/j.celrep.2017.04.039.

28.

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.

Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators.

J Infect Dis. 2017 Jul 1;216(1):14-21. doi: 10.1093/infdis/jix242.

29.

Surveillance states.

Dash P, Thomas PG.

Nat Struct Mol Biol. 2017 Apr 6;24(4):339-341. doi: 10.1038/nsmb.3398. No abstract available.

PMID:
28384134
30.

Prognostication of traumatic brain injury outcomes in older trauma patients: A novel risk assessment tool based on initial cranial CT findings.

Stawicki SP, Wojda TR, Nuschke JD, Mubang RN, Cipolla J, Hoff WS, Hoey BA, Thomas PG, Sweeney J, Ackerman D, Hosey J, Falowski S.

Int J Crit Illn Inj Sci. 2017 Jan-Mar;7(1):23-31. doi: 10.4103/IJCIIS.IJCIIS_2_17.

31.

Towards integrating extracellular matrix and immunological pathways.

Boyd DF, Thomas PG.

Cytokine. 2017 Oct;98:79-86. doi: 10.1016/j.cyto.2017.03.004. Epub 2017 Mar 18. Review.

PMID:
28325629
32.

Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.

Samarasinghe AE, Melo RC, Duan S, LeMessurier KS, Liedmann S, Surman SL, Lee JJ, Hurwitz JL, Thomas PG, McCullers JA.

J Immunol. 2017 Apr 15;198(8):3214-3226. doi: 10.4049/jimmunol.1600787. Epub 2017 Mar 10.

33.

Targeting phospholipase D in cancer, infection and neurodegenerative disorders.

Brown HA, Thomas PG, Lindsley CW.

Nat Rev Drug Discov. 2017 May;16(5):351-367. doi: 10.1038/nrd.2016.252. Epub 2017 Feb 17. Review.

34.

Identifying T Cell Receptors from High-Throughput Sequencing: Dealing with Promiscuity in TCRα and TCRβ Pairing.

Lee ES, Thomas PG, Mold JE, Yates AJ.

PLoS Comput Biol. 2017 Jan 19;13(1):e1005313. doi: 10.1371/journal.pcbi.1005313. eCollection 2017 Jan.

35.

Establishment of memory CD8+ T cells with live attenuated influenza virus across different vaccination doses.

Wang Z, Kedzierski L, Nuessing S, Chua BY, Quiñones-Parra SM, Huber VC, Jackson DC, Thomas PG, Kedzierska K.

J Gen Virol. 2016 Dec;97(12):3205-3214. doi: 10.1099/jgv.0.000651. Epub 2016 Nov 2.

PMID:
27902386
36.

Stress Kinase GCN2 Controls the Proliferative Fitness and Trafficking of Cytotoxic T Cells Independent of Environmental Amino Acid Sensing.

Van de Velde LA, Guo XJ, Barbaric L, Smith AM, Oguin TH 3rd, Thomas PG, Murray PJ.

Cell Rep. 2016 Nov 22;17(9):2247-2258. doi: 10.1016/j.celrep.2016.10.079.

37.

Cell-Intrinsic Barriers of T Cell-Based Immunotherapy.

Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA.

Trends Mol Med. 2016 Dec;22(12):1000-1011. doi: 10.1016/j.molmed.2016.10.002. Epub 2016 Nov 4. Review.

38.

Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.

Kohlhapp FJ, Huelsmann EJ, Lacek AT, Schenkel JM, Lusciks J, Broucek JR, Goldufsky JW, Hughes T, Zayas JP, Dolubizno H, Sowell RT, Kühner R, Burd S, Kubasiak JC, Nabatiyan A, Marshall S, Bommareddy PK, Li S, Newman JH, Monken CE, Shafikhani SH, Marzo AL, Guevara-Patino JA, Lasfar A, Thomas PG, Lattime EC, Kaufman HL, Zloza A.

Cell Rep. 2016 Oct 18;17(4):957-965. doi: 10.1016/j.celrep.2016.09.068.

39.

MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates.

Greene JM, Dash P, Roy S, McMurtrey C, Awad W, Reed JS, Hammond KB, Abdulhaqq S, Wu HL, Burwitz BJ, Roth BF, Morrow DW, Ford JC, Xu G, Bae JY, Crank H, Legasse AW, Dang TH, Greenaway HY, Kurniawan M, Gold MC, Harriff MJ, Lewinsohn DA, Park BS, Axthelm MK, Stanton JJ, Hansen SG, Picker LJ, Venturi V, Hildebrand W, Thomas PG, Lewinsohn DM, Adams EJ, Sacha JB.

Mucosal Immunol. 2017 May;10(3):802-813. doi: 10.1038/mi.2016.91. Epub 2016 Oct 19.

40.

DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death.

Thapa RJ, Ingram JP, Ragan KB, Nogusa S, Boyd DF, Benitez AA, Sridharan H, Kosoff R, Shubina M, Landsteiner VJ, Andrake M, Vogel P, Sigal LJ, tenOever BR, Thomas PG, Upton JW, Balachandran S.

Cell Host Microbe. 2016 Nov 9;20(5):674-681. doi: 10.1016/j.chom.2016.09.014. Epub 2016 Oct 13.

41.

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy.

Kamei A, Gao G, Neale G, Loh LN, Vogel P, Thomas PG, Tuomanen EI, Murray PJ.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6153-E6161. Epub 2016 Sep 26.

42.

Injury and fatality risks in aeromedical transport: focus on prevention.

Hon HH, Wojda TR, Barry N, MacBean U, Anagnostakos JP, Evans DC, Thomas PG, Stawicki SP.

J Surg Res. 2016 Aug;204(2):297-303. doi: 10.1016/j.jss.2016.05.003. Epub 2016 May 10.

PMID:
27565064
43.

Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination.

Ellebedy AH, Jackson KJ, Kissick HT, Nakaya HI, Davis CW, Roskin KM, McElroy AK, Oshansky CM, Elbein R, Thomas S, Lyon GM, Spiropoulou CF, Mehta AK, Thomas PG, Boyd SD, Ahmed R.

Nat Immunol. 2016 Oct;17(10):1226-34. doi: 10.1038/ni.3533. Epub 2016 Aug 15.

44.

Maintenance of the EBV-specific CD8+ TCRαβ repertoire in immunosuppressed lung transplant recipients.

Nguyen TH, Bird NL, Grant EJ, Miles JJ, Thomas PG, Kotsimbos TC, Mifsud NA, Kedzierska K.

Immunol Cell Biol. 2017 Jan;95(1):77-86. doi: 10.1038/icb.2016.71. Epub 2016 Oct 4.

45.

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens.

Meliopoulos VA, Van de Velde LA, Van de Velde NC, Karlsson EA, Neale G, Vogel P, Guy C, Sharma S, Duan S, Surman SL, Jones BG, Johnson MD, Bosio C, Jolly L, Jenkins RG, Hurwitz JL, Rosch JW, Sheppard D, Thomas PG, Murray PJ, Schultz-Cherry S.

PLoS Pathog. 2016 Aug 9;12(8):e1005804. doi: 10.1371/journal.ppat.1005804. eCollection 2016 Aug.

46.

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.

Nogusa S, Thapa RJ, Dillon CP, Liedmann S, Oguin TH 3rd, Ingram JP, Rodriguez DA, Kosoff R, Sharma S, Sturm O, Verbist K, Gough PJ, Bertin J, Hartmann BM, Sealfon SC, Kaiser WJ, Mocarski ES, López CB, Thomas PG, Oberst A, Green DR, Balachandran S.

Cell Host Microbe. 2016 Jul 13;20(1):13-24. doi: 10.1016/j.chom.2016.05.011. Epub 2016 Jun 16.

47.

Temporal changes in hematologic markers after splenectomy, splenic embolization, and observation for trauma.

Wernick B, Cipriano A, Odom SR, MacBean U, Mubang RN, Wojda TR, Liu S, Serres S, Evans DC, Thomas PG, Cook CH, Stawicki SP.

Eur J Trauma Emerg Surg. 2017 Jun;43(3):399-409. doi: 10.1007/s00068-016-0679-0. Epub 2016 May 11.

PMID:
27167236
48.

Respiratory Mucosal Proteome Quantification in Human Influenza Infections.

Marion T, Elbahesh H, Thomas PG, DeVincenzo JP, Webby R, Schughart K.

PLoS One. 2016 Apr 18;11(4):e0153674. doi: 10.1371/journal.pone.0153674. eCollection 2016.

49.

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.

Valkenburg SA, Josephs TM, Clemens EB, Grant EJ, Nguyen TH, Wang GC, Price DA, Miller A, Tong SY, Thomas PG, Doherty PC, Rossjohn J, Gras S, Kedzierska K.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4440-5. doi: 10.1073/pnas.1603106113. Epub 2016 Mar 31.

50.

Balancing Immune Protection and Immune Pathology by CD8(+) T-Cell Responses to Influenza Infection.

Duan S, Thomas PG.

Front Immunol. 2016 Feb 5;7:25. doi: 10.3389/fimmu.2016.00025. eCollection 2016. Review.

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