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Systematic Review: Anxiety in Children and Adolescents With Chronic Medical Conditions.

Cobham VE, Hickling A, Kimball H, Thomas HJ, Scott JG, Middeldorp CM.

J Am Acad Child Adolesc Psychiatry. 2019 Oct 29. pii: S0890-8567(19)32110-0. doi: 10.1016/j.jaac.2019.10.010. [Epub ahead of print] Review.


Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring.

Cleal JK, Bruce KD, Shearer JL, Thomas H, Plume J, Gregory L, Shepard JN, Spiers-Fitzgerald KL, Mani R, Lewis RM, Lillycrop KA, Hanson MA, Byrne CD, Cagampang FR.

Int J Mol Sci. 2019 Oct 30;20(21). pii: E5408. doi: 10.3390/ijms20215408.


IL-21 regulates SOCS1 expression in autoreactive CD8+ T cells but is not required for acquisition of CTL activity in the islets of non-obese diabetic mice.

Sutherland APR, Graham KL, Papadimitriou M, Jhala G, Trivedi P, Catterall T, Fynch S, Kay TWH, Thomas HE.

Sci Rep. 2019 Oct 25;9(1):15302. doi: 10.1038/s41598-019-51636-5.


Staff Perceptions of Chaplains in a Neurosciences Critical Care Unit.

Purvis TE, Powell B, Biba G, Conti D, Crowe TY, Thomas H, Carhuapoma JR, Probasco J, Teague P, Saylor D.

J Relig Health. 2019 Oct 24. doi: 10.1007/s10943-019-00935-2. [Epub ahead of print]


A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome.

Gittens WH, Johnson DJ, Allison RM, Cooper TJ, Thomas H, Neale MJ.

Nat Commun. 2019 Oct 24;10(1):4846. doi: 10.1038/s41467-019-12802-5.


Medical equipment donation in low-resource settings: a review of the literature and guidelines for surgery and anaesthesia in low-income and middle-income countries.

Marks IH, Thomas H, Bakhet M, Fitzgerald E.

BMJ Glob Health. 2019 Sep 29;4(5):e001785. doi: 10.1136/bmjgh-2019-001785. eCollection 2019.


Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report.

Dominguez-Valentin M, Seppälä TT, Sampson JR, Macrae F, Winship I, Evans DG, Scott RJ, Burn J, Möslein G, Bernstein I, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lindblom A, Plazzer JP, Tjandra D, Thomas H, Green K, Lalloo F, Crosbie EJ, Hill J, Capella G, Pineda M, Navarro M, Vidal JB, Rønlund K, Nielsen RT, Yilmaz M, Elvang LL, Katz L, Nielsen M, Ten Broeke SW, Nakken S, Hovig E, Sunde L, Kloor M, Knebel Doeberitz MV, Ahadova A, Lindor N, Steinke-Lange V, Holinski-Feder E, Mecklin JP, Møller P.

Hered Cancer Clin Pract. 2019 Oct 14;17:28. doi: 10.1186/s13053-019-0127-3. eCollection 2019.


Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.

Bensellam M, Shi YC, Chan JY, Laybutt DR, Chae H, Abou-Samra M, Pappas EG, Thomas HE, Gilon P, Jonas JC.

Diabetologia. 2019 Oct 17. doi: 10.1007/s00125-019-05008-3. [Epub ahead of print]


Advanced Methods for the Analysis of Altered Pre-mRNA Splicing in Yeast and Disease.

Thomas HB, O'Keefe RT.

Methods Mol Biol. 2019;2049:131-140. doi: 10.1007/978-1-4939-9736-7_8.


Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.

Willoughby CE, Jiang Y, Thomas HD, Willmore E, Kyle S, Wittner A, Phillips N, Zhao Y, Tudhope SJ, Prendergast L, Junge G, Madia Lourenco L, Finlay MRV, Turner P, Munck JM, Griffin RJ, Rennison T, Pickles J, Cano C, Newell DR, Reeves HL, Ryan AJ, Wedge SR.

J Clin Invest. 2019 Oct 3. pii: 127483. doi: 10.1172/JCI127483. [Epub ahead of print]


'Protecting Life in Global Health Assistance'? Towards a framework for assessing the health systems impact of the expanded Global Gag Rule.

Schaaf M, Maistrellis E, Thomas H, Cooper B; GGR Research Working Group .

BMJ Glob Health. 2019 Sep 11;4(5):e001786. doi: 10.1136/bmjgh-2019-001786. eCollection 2019. Review.


Soluble FAS ligand is not required for pancreatic islet inflammation or beta-cell destruction in non-obese diabetic mice.

Trivedi PM, Fynch S, Kennedy LM, Chee J, Krishnamurthy B, O'Reilly LA, Strasser A, Kay TWH, Thomas HE.

Cell Death Discov. 2019 Sep 23;5:136. doi: 10.1038/s41420-019-0217-z. eCollection 2019.


The contribution of bullying victimisation to the burden of anxiety and depressive disorders in Australia.

Jadambaa A, Thomas HJ, Scott JG, Graves N, Brain D, Pacella R.

Epidemiol Psychiatr Sci. 2019 Sep 19:1-23. doi: 10.1017/S2045796019000489. [Epub ahead of print]


Paediatric proton therapy.

Thomas H, Timmermann B.

Br J Radiol. 2019 Sep 19:20190601. doi: 10.1259/bjr.20190601. [Epub ahead of print]


The use of adenosine in the assessment of stable coronary heart disease.

Ripley DP, Jenkins NP, Thomas HE.

J R Coll Physicians Edinb. 2019 Sep;49(3):182-184. doi: 10.4997/JRCPE.2019.302. No abstract available.


Phlda3 regulates beta cell survival during stress.

Bensellam M, Chan JY, Lee K, Joglekar MV, Hardikar AA, Loudovaris T, Thomas HE, Jonas JC, Laybutt DR.

Sci Rep. 2019 Sep 6;9(1):12827. doi: 10.1038/s41598-019-49289-5.


Quantitative Fragmentation Model for Bottom-Up Shotgun Lipidomics.

Schuhmann K, Moon H, Thomas H, Ackerman JM, Groessl M, Wagner N, Kellmann M, Henry I, Nadler A, Shevchenko A.

Anal Chem. 2019 Sep 17;91(18):12085-12093. doi: 10.1021/acs.analchem.9b03270. Epub 2019 Sep 5.


A homozygous missense variant in CHRM3 associated with familial urinary bladder disease.

Beaman GM, Galatà G, Teik KW, Urquhart JE, Aishah A, O'Sullivan J, Bhaskar SS, Wood KA, Thomas HB, O'Keefe RT, Woolf AS, Stuart HM, Newman WG.

Clin Genet. 2019 Aug 23. doi: 10.1111/cge.13631. [Epub ahead of print]


The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer.

Jones D, Wilson L, Thomas H, Gaughan L, Wade MA.

Cancers (Basel). 2019 Aug 6;11(8). pii: E1122. doi: 10.3390/cancers11081122.


Deep seam and minesoil carbon sequestration potential of the South Wales Coalfield, UK.

Detheridge A, Hosking LJ, Thomas HR, Sarhosis V, Gwynn-Jones D, Scullion J.

J Environ Manage. 2019 Oct 15;248:109325. doi: 10.1016/j.jenvman.2019.109325. Epub 2019 Jul 31.


The association between five forms of child maltreatment and depressive and anxiety disorders: A systematic review and meta-analysis.

Gardner MJ, Thomas HJ, Erskine HE.

Child Abuse Negl. 2019 Oct;96:104082. doi: 10.1016/j.chiabu.2019.104082. Epub 2019 Jul 30.


Comparison of regional lung perfusion response on longitudinal MAA SPECT/CT in lung cancer patients treated with and without functional tissue-avoidance radiation therapy.

Thomas HMT, Zeng J, Lee HJ Jr, Sasidharan BK, Kinahan PE, Miyaoka RS, Vesselle HJ, Rengan R, Bowen SR.

Br J Radiol. 2019 Nov;92(1103):20190174. doi: 10.1259/bjr.20190174. Epub 2019 Aug 12.


Use of community-based subcutaneous furosemide in advanced heart failure: experience of a new service in the north-east of England.

Brown A, Robson J, Armstrong L, Matthews I, Runnett C, Thomas H.

Future Healthc J. 2019 Mar;6(Suppl 1):19. doi: 10.7861/futurehosp.6-1-s19. No abstract available.


Surveillance arterioveNous fistulAs using ultRasound (SONAR) trial in haemodialysis patients: a study protocol for a multicentre observational study.

Richards J, Hossain M, Summers D, Slater M, Bartlett M, Kosmoliaptsis V, Wilson EC, Lagaac R, Sidders A, Foley C, Laing E, Hopkins V, Fitzpatrick-Creamer C, Hudson C, Thomas H, Turner S, Tambyraja A, Somalanka S, Hunter J, Dutta S, Lawman S, Salter T, Aslam M, Bagul A, Sivaprakasam R, Smith G, Moinuddin Z, Knight S, Gibbs P, Motallebzadeh R, Barnett N, Pettigrew G; SONAR trial group.

BMJ Open. 2019 Jul 23;9(7):e031210. doi: 10.1136/bmjopen-2019-031210.


Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database.

Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A, Lopez-Köstner F, Gluck N, Katz LH, Heinimann K, Vaccaro CA, Büttner R, Görgens H, Holinski-Feder E, Morak M, Holzapfel S, Hüneburg R, Knebel Doeberitz MV, Loeffler M, Rahner N, Schackert HK, Steinke-Lange V, Schmiegel W, Vangala D, Pylvänäinen K, Renkonen-Sinisalo L, Hopper JL, Win AK, Haile RW, Lindor NM, Gallinger S, Le Marchand L, Newcomb PA, Figueiredo JC, Thibodeau SN, Wadt K, Therkildsen C, Okkels H, Ketabi Z, Moreira L, Sánchez A, Serra-Burriel M, Pineda M, Navarro M, Blanco I, Green K, Lalloo F, Crosbie EJ, Hill J, Denton OG, Frayling IM, Rødland EA, Vasen H, Mints M, Neffa F, Esperon P, Alvarez K, Kariv R, Rosner G, Pinero TA, Gonzalez ML, Kalfayan P, Tjandra D, Winship IM, Macrae F, Möslein G, Mecklin JP, Nielsen M, Møller P.

Genet Med. 2019 Jul 24. doi: 10.1038/s41436-019-0596-9. [Epub ahead of print]


Burden of multidrug-resistant tuberculosis in England: a focus on prevalent cases.

Lalor MK, Perkins S, Thomas HL.

Int J Tuberc Lung Dis. 2019 Jun 1;23(6):707-713. doi: 10.5588/ijtld.18.0399.


Disease modelling of core pre-mRNA splicing factor haploinsufficiency.

Wood KA, Rowlands CF, Qureshi WMS, Thomas HB, Buczek WA, Briggs TA, Hubbard SJ, Hentges K, Newman WG, O'Keefe RT.

Hum Mol Genet. 2019 Jul 13. pii: ddz169. doi: 10.1093/hmg/ddz169. [Epub ahead of print]


Organoid modelling of NAFLD.

Thomas H.

Nat Rev Gastroenterol Hepatol. 2019 Aug;16(8):454-455. doi: 10.1038/s41575-019-0181-3. No abstract available.


Theory of a cavity around a large floating sphere in complex (dusty) plasma.

Khrapak S, Huber P, Thomas H, Naumkin V, Molotkov V, Lipaev A.

Phys Rev E. 2019 May;99(5-1):053210. doi: 10.1103/PhysRevE.99.053210.


Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4.

Myers SM, Miller DC, Molyneux L, Arasta M, Bawn RH, Blackburn TJ, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hammonds T, Hardcastle IR, Harnor SJ, Heptinstall AB, Lochhead PA, Martin MP, Martin NC, Newell DR, Owen PJ, Pang LC, Reuillon T, Rigoreau LJM, Thomas HD, Tucker JA, Wang LZ, Wong AC, Noble MEM, Wedge SR, Cano C.

Eur J Med Chem. 2019 Sep 15;178:530-543. doi: 10.1016/j.ejmech.2019.05.057. Epub 2019 May 25.


Social Network Analysis of Dementia Wards in Psychiatric Hospitals to Explore the Advancement of Personhood in Patients with Alzheimer's Disease.

Lazzari C, Kotera Y, Thomas H.

Curr Alzheimer Res. 2019;16(6):505-517. doi: 10.2174/1567205016666190612160955.


Chemical characterization of unconventional palm oils from Hyophorbe indica and two other endemic Arecaceae species from Reunion Island.

Caro Y, Petit T, Grondin I, Clerc P, Thomas H, Giuffrida D, Giocastro B, Tranchida PQ, Aloisi I, Murador D, Mondello L, Dufossé L.

Nat Prod Res. 2019 Jun 7:1-9. doi: 10.1080/14786419.2019.1624959. [Epub ahead of print]


Relapse Rates in Patients with Clubfoot Treated Using the Ponseti Method Increase with Time: A Systematic Review.

Thomas HM, Sangiorgio SN, Ebramzadeh E, Zionts LE.

JBJS Rev. 2019 May;7(5):e6. doi: 10.2106/JBJS.RVW.18.00124.


Exploring diagnostic validity of the autism diagnostic observation schedule-2 in South Korean toddlers and preschoolers.

Lee KS, Chung SJ, Thomas HR, Park J, Kim SH.

Autism Res. 2019 Sep;12(9):1356-1366. doi: 10.1002/aur.2125. Epub 2019 May 21.


PROCESS AND SYSTEMS: A cohort study to evaluate the impact of service centralisation for emergency admissions with acute heart failure.

Wilkinson C, Thomas H, McMeekin P, Price C.

Future Healthc J. 2019 Feb;6(1):41-46. doi: 10.7861/futurehosp.6-1-41.


Prevalence of traditional bullying and cyberbullying among children and adolescents in Australia: A systematic review and meta-analysis.

Jadambaa A, Thomas HJ, Scott JG, Graves N, Brain D, Pacella R.

Aust N Z J Psychiatry. 2019 Sep;53(9):878-888. doi: 10.1177/0004867419846393. Epub 2019 May 9.


Polymorphisms in Natural Killer Cell Receptor Protein 2D (NKG2D) as a Risk Factor for Cholangiocarcinoma.

Wadsworth CA, Dixon PH, Taylor-Robinson S, Kim JU, Zabron AA, Wong JH, Chapman MH, McKay SC, Spalding DR, Wasan HS, Pereira SP, Thomas HC, Whittaker JC, Williamson C, Khan SA.

J Clin Exp Hepatol. 2019 Mar-Apr;9(2):171-175. doi: 10.1016/j.jceh.2018.06.521. Epub 2018 Jul 20.


Traditional plant functional groups explain variation in economic but not size-related traits across the tundra biome.

Thomas HJD, Myers-Smith IH, Bjorkman AD, Elmendorf SC, Blok D, Cornelissen JHC, Forbes BC, Hollister RD, Normand S, Prevéy JS, Rixen C, Schaepman-Strub G, Wilmking M, Wipf S, Cornwell WK, Kattge J, Goetz SJ, Guay KC, Alatalo JM, Anadon-Rosell A, Angers-Blondin S, Berner LT, Björk RG, Buchwal A, Buras A, Carbognani M, Christie K, Siegwart Collier L, Cooper EJ, Eskelinen A, Frei ER, Grau O, Grogan P, Hallinger M, Heijmans MMPD, Hermanutz L, Hudson JMG, Hülber K, Iturrate-Garcia M, Iversen CM, Jaroszynska F, Johnstone JF, Kaarlejärvi E, Kulonen A, Lamarque LJ, Lévesque E, Little CJ, Michelsen A, Milbau A, Nabe-Nielsen J, Nielsen SS, Ninot JM, Oberbauer SF, Olofsson J, Onipchenko VG, Petraglia A, Rumpf SB, Semenchuk PR, Soudzilovskaia NA, Spasojevic MJ, Speed JDM, Tape KD, Te Beest M, Tomaselli M, Trant A, Treier UA, Venn S, Vowles T, Weijers S, Zamin T, Atkin OK, Bahn M, Blonder B, Campetella G, Cerabolini BEL, Chapin Iii FS, Dainese M, de Vries FT, Díaz S, Green W, Jackson RB, Manning P, Niinemets Ü, Ozinga WA, Peñuelas J, Reich PB, Schamp B, Sheremetev S, van Bodegom PM.

Glob Ecol Biogeogr. 2019 Jan;28(2):78-95. doi: 10.1111/geb.12783. Epub 2018 Nov 16.


Identifying a specific small molecule to reverse intestinal barrier loss.

Thomas H.

Nat Rev Gastroenterol Hepatol. 2019 Jun;16(6):325. doi: 10.1038/s41575-019-0149-3. No abstract available.



Harrison EM, Thomas HS, Weiser TG.

Br J Surg. 2019 May;106(6):802-803. doi: 10.1002/bjs.11194. No abstract available.


LSEC stretch promotes fibrosis during hepatic vascular congestion.

Thomas H.

Nat Rev Gastroenterol Hepatol. 2019 May;16(5):262-263. doi: 10.1038/s41575-019-0146-6. No abstract available.


IL-6 drives niche formation in pancreatic cancer liver metastasis.

Thomas H.

Nat Rev Gastroenterol Hepatol. 2019 May;16(5):263. doi: 10.1038/s41575-019-0138-6. No abstract available.


Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report.

Seppälä TT, Ahadova A, Dominguez-Valentin M, Macrae F, Evans DG, Therkildsen C, Sampson J, Scott R, Burn J, Möslein G, Bernstein I, Holinski-Feder E, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lautrup CK, Lindblom A, Plazzer JP, Winship I, Tjandra D, Katz LH, Aretz S, Hüneburg R, Holzapfel S, Heinimann K, Valle AD, Neffa F, Gluck N, de Vos Tot Nederveen Cappel WH, Vasen H, Morak M, Steinke-Lange V, Engel C, Rahner N, Schmiegel W, Vangala D, Thomas H, Green K, Lalloo F, Crosbie EJ, Hill J, Capella G, Pineda M, Navarro M, Blanco I, Ten Broeke S, Nielsen M, Ljungmann K, Nakken S, Lindor N, Frayling I, Hovig E, Sunde L, Kloor M, Mecklin JP, Kalager M, Møller P.

Hered Cancer Clin Pract. 2019 Feb 28;17:8. doi: 10.1186/s13053-019-0106-8. eCollection 2019.


Mendelian randomization reveals causal effects of the gut microbiota.

Thomas H.

Nat Rev Gastroenterol Hepatol. 2019 Apr;16(4):198-199. doi: 10.1038/s41575-019-0133-y. No abstract available.


Connecting the pieces: uncovering the molecular basis for long-distance communication through plant grafting.

Thomas HR, Frank MH.

New Phytol. 2019 Jul;223(2):582-589. doi: 10.1111/nph.15772. Epub 2019 Mar 30. Review.


Lameness prevalence in a random sample of UK dairy herds.

Randall LV, Thomas HJ, Remnant JG, Bollard NJ, Huxley JN.

Vet Rec. 2019 Mar 16;184(11):350. doi: 10.1136/vr.105047. Epub 2019 Mar 1. No abstract available.


Maternal Obesity During Pregnancy and Lactation Influences Offspring Obesogenic Adipogenesis but Not Developmental Adipogenesis in Mice.

Sellayah D, Thomas H, Lanham SA, Cagampang FR.

Nutrients. 2019 Feb 27;11(3). pii: E495. doi: 10.3390/nu11030495.


Protocol for a mixed-methods exploratory investigation of care following intensive care discharge: the REFLECT study.

Vollam S, Gustafson O, Hinton L, Morgan L, Pattison N, Thomas H, Young JD, Watkinson P.

BMJ Open. 2019 Jan 25;9(1):e027838. doi: 10.1136/bmjopen-2018-027838.


Seed predation increases from the Arctic to the Equator and from high to low elevations.

Hargreaves AL, Suárez E, Mehltreter K, Myers-Smith I, Vanderplank SE, Slinn HL, Vargas-Rodriguez YL, Haeussler S, David S, Muñoz J, Carlos Almazán-Núñez R, Loughnan D, Benning JW, Moeller DA, Brodie JF, Thomas HJD, Morales M PA.

Sci Adv. 2019 Feb 20;5(2):eaau4403. doi: 10.1126/sciadv.aau4403. eCollection 2019 Feb.


Programmable transparent organic luminescent tags.

Gmelch M, Thomas H, Fries F, Reineke S.

Sci Adv. 2019 Feb 1;5(2):eaau7310. doi: 10.1126/sciadv.aau7310. eCollection 2019 Feb.

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