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Items: 1 to 50 of 128

1.

Exaggerated cardiovascular responses to treadmill running in rats with peripheral arterial insufficiency.

Kuczmarski JM, Unrath K, Thomas GD.

Am J Physiol Heart Circ Physiol. 2018 Jan 1;314(1):H114-H121. doi: 10.1152/ajpheart.00401.2017. Epub 2017 Oct 6.

PMID:
28986360
2.

Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis.

Marcovecchio PM, Thomas GD, Mikulski Z, Ehinger E, Mueller KAL, Blatchley A, Wu R, Miller YI, Nguyen AT, Taylor AM, McNamara CA, Ley K, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2043-2052. doi: 10.1161/ATVBAHA.117.309123. Epub 2017 Sep 21.

PMID:
28935758
3.

Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry.

Thomas GD, Hamers AAJ, Nakao C, Marcovecchio P, Taylor AM, McSkimming C, Nguyen AT, McNamara CA, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1548-1558. doi: 10.1161/ATVBAHA.117.309145. Epub 2017 Jun 8.

4.

The role played by oxidative stress in evoking the exercise pressor reflex in health and simulated peripheral artery disease.

Harms JE, Kuczmarski JM, Kim JS, Thomas GD, Kaufman MP.

J Physiol. 2017 Jul 1;595(13):4365-4378. doi: 10.1113/JP273816. Epub 2017 May 24.

5.

Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function.

Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC.

Immunity. 2016 Nov 15;45(5):975-987. doi: 10.1016/j.immuni.2016.10.011. Epub 2016 Nov 1.

6.

2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.

Zhu YP, Thomas GD, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1722-33. doi: 10.1161/ATVBAHA.116.304054. Epub 2016 Jul 7. Review.

7.

Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.

Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC.

Nat Immunol. 2015 Dec;16(12):1228-34. doi: 10.1038/ni.3321. Epub 2015 Nov 2.

8.

Patrolling monocytes control tumor metastasis to the lung.

Hanna RN, Cekic C, Sag D, Tacke R, Thomas GD, Nowyhed H, Herrley E, Rasquinha N, McArdle S, Wu R, Peluso E, Metzger D, Ichinose H, Shaked I, Chodaczek G, Biswas SK, Hedrick CC.

Science. 2015 Nov 20;350(6263):985-90. doi: 10.1126/science.aac9407. Epub 2015 Oct 22.

9.

Cutting Edge: The Orphan Nuclear Receptor Nr4a1 Regulates CD8+ T Cell Expansion and Effector Function through Direct Repression of Irf4.

Nowyhed HN, Huynh TR, Thomas GD, Blatchley A, Hedrick CC.

J Immunol. 2015 Oct 15;195(8):3515-9. doi: 10.4049/jimmunol.1403027. Epub 2015 Sep 11.

10.

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.

Cook PC, Owen H, Deaton AM, Borger JG, Brown SL, Clouaire T, Jones GR, Jones LH, Lundie RJ, Marley AK, Morrison VL, Phythian-Adams AT, Wachter E, Webb LM, Sutherland TE, Thomas GD, Grainger JR, Selfridge J, McKenzie AN, Allen JE, Fagerholm SC, Maizels RM, Ivens AC, Bird A, MacDonald AS.

Nat Commun. 2015 Apr 24;6:6920. doi: 10.1038/ncomms7920.

11.

Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.

Jones LH, Cook PC, Ivens AC, Thomas GD, Phythian-Adams AT, Allen JE, MacDonald AS.

Int Immunol. 2015 Nov;27(11):589-96. doi: 10.1093/intimm/dxv020. Epub 2015 Apr 20.

12.

The nuclear receptor nr4a1 controls CD8 T cell development through transcriptional suppression of runx3.

Nowyhed HN, Huynh TR, Blatchley A, Wu R, Thomas GD, Hedrick CC.

Sci Rep. 2015 Mar 12;5:9059. doi: 10.1038/srep09059.

13.

Secular changes in prediabetes indicators among older-adult Americans, 1999-2010.

Caspersen CJ, Thomas GD, Beckles GL, Bullard KM.

Am J Prev Med. 2015 Mar;48(3):253-63. doi: 10.1016/j.amepre.2014.10.004. Epub 2015 Jan 15.

14.

Functional sympatholysis in hypertension.

Thomas GD.

Auton Neurosci. 2015 Mar;188:64-8. doi: 10.1016/j.autneu.2014.10.019. Epub 2014 Oct 23. Review.

15.

Functional muscle ischemia in Duchenne and Becker muscular dystrophy.

Thomas GD.

Front Physiol. 2013 Dec 18;4:381. doi: 10.3389/fphys.2013.00381. Review.

16.

IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1.

Jenkins SJ, Ruckerl D, Thomas GD, Hewitson JP, Duncan S, Brombacher F, Maizels RM, Hume DA, Allen JE.

J Exp Med. 2013 Oct 21;210(11):2477-91. doi: 10.1084/jem.20121999. Epub 2013 Oct 7.

17.

Dual AAV therapy ameliorates exercise-induced muscle injury and functional ischemia in murine models of Duchenne muscular dystrophy.

Zhang Y, Yue Y, Li L, Hakim CH, Zhang K, Thomas GD, Duan D.

Hum Mol Genet. 2013 Sep 15;22(18):3720-9. doi: 10.1093/hmg/ddt224. Epub 2013 May 15.

18.

Differential effects of nebivolol versus metoprolol on functional sympatholysis in hypertensive humans.

Price A, Raheja P, Wang Z, Arbique D, Adams-Huet B, Mitchell JH, Victor RG, Thomas GD, Vongpatanasin W.

Hypertension. 2013 Jun;61(6):1263-9. doi: 10.1161/HYPERTENSIONAHA.113.01302. Epub 2013 Apr 1.

19.

Caspersen et al. respond to Arredondo.

Caspersen CJ, Thomas GD, Boseman LA, Beckles GL, Albright AL.

Am J Public Health. 2013 Feb;103(2):e2. doi: 10.2105/AJPH.2012.301133. Epub 2012 Dec 13. No abstract available.

20.

Tadalafil alleviates muscle ischemia in patients with Becker muscular dystrophy.

Martin EA, Barresi R, Byrne BJ, Tsimerinov EI, Scott BL, Walker AE, Gurudevan SV, Anene F, Elashoff RM, Thomas GD, Victor RG.

Sci Transl Med. 2012 Nov 28;4(162):162ra155. doi: 10.1126/scitranslmed.3004327.

21.

Treatment with a nitric oxide-donating NSAID alleviates functional muscle ischemia in the mouse model of Duchenne muscular dystrophy.

Thomas GD, Ye J, De Nardi C, Monopoli A, Ongini E, Victor RG.

PLoS One. 2012;7(11):e49350. doi: 10.1371/journal.pone.0049350. Epub 2012 Nov 5.

22.

The biology of nematode- and IL4Rα-dependent murine macrophage polarization in vivo as defined by RNA-Seq and targeted lipidomics.

Thomas GD, Rückerl D, Maskrey BH, Whitfield PD, Blaxter ML, Allen JE.

Blood. 2012 Dec 13;120(25):e93-e104. doi: 10.1182/blood-2012-07-442640. Epub 2012 Oct 16.

23.

Aging, diabetes, and the public health system in the United States.

Caspersen CJ, Thomas GD, Boseman LA, Beckles GL, Albright AL.

Am J Public Health. 2012 Aug;102(8):1482-97. doi: 10.2105/AJPH.2011.300616. Epub 2012 Jun 14. Review.

24.

Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate-tolerant rats and humans.

Fadel PJ, Farias Iii M, Gallagher KM, Wang Z, Thomas GD.

J Physiol. 2012 Jan 15;590(2):395-407. doi: 10.1113/jphysiol.2011.218917. Epub 2011 Nov 21.

25.

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.

Stevens KN, Garcia-Closas M, Fredericksen Z, Kosel M, Pankratz VS, Hopper JL, Dite GS, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Tollenaar RA, Fasching PA, Beckmann MW, Hein A, Ekici AB, Johnson N, Peto J, dos Santos Silva I, Gibson L, Sawyer E, Tomlinson I, Kerin MJ, Chanock S, Lissowska J, Hunter DJ, Hoover RN, Thomas GD, Milne RL, Arias Pérez JI, González-Neira A, Benítez J, Burwinkel B, Meindl A, Schmutzler RK, Bartrar CR, Hamann U, Ko YD, Brüning T, Chang-Claude J, Hein R, Wang-Gohrke S, Dörk T, Schürmann P, Bremer M, Hillemanns P, Bogdanova N, Zalutsky JV, Rogov YI, Antonenkova N, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen J, Chenevix-Trench G, Chen X, Peterlongo P, Bonanni B, Bernard L, Manoukian S, Wang X, Cerhan J, Vachon CM, Olson J, Giles GG, Baglietto L, McLean CA, Severi G, John EM, Miron A, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Andrulis I, Knight JA, Glendon G, Mulligan AM, Cox A, Brock IW, Elliott G, Cross SS, Pharoah PP, Dunning AM, Pooley KA, Humphreys MK, Wang J, Kang D, Yoo KY, Noh DY, Sangrajrang S, Gabrieau V, Brennan P, McKay J, Anton-Culver H, Ziogas A, Couch FJ, Easton DF; GENICA Network; kConFab Investigators; Australian Ovarian Cancer Study Group.

Br J Cancer. 2011 Dec 6;105(12):1934-9. doi: 10.1038/bjc.2011.448. Epub 2011 Oct 27.

26.

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer.

Milne RL, Goode EL, García-Closas M, Couch FJ, Severi G, Hein R, Fredericksen Z, Malats N, Zamora MP, Arias Pérez JI, Benítez J, Dörk T, Schürmann P, Karstens JH, Hillemanns P, Cox A, Brock IW, Elliot G, Cross SS, Seal S, Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC, Huang CS, Hou MF, Nordestgaard BG, Bojesen SE, Lanng C, Grenaker Alnæs G, Kristensen V, Børrensen-Dale AL, Hopper JL, Dite GS, Apicella C, Southey MC, Lambrechts D, Yesilyurt BT, Floris G, Leunen K, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Chang-Claude J, Wang-Gohrke S, Radice P, Peterlongo P, Manoukian S, Barile M, Giles GG, Baglietto L, John EM, Miron A, Chanock SJ, Lissowska J, Sherman ME, Figueroa JD, Bogdanova NV, Antonenkova NN, Zalutsky IV, Rogov YI, Fasching PA, Bayer CM, Ekici AB, Beckmann MW, Brenner H, Müller H, Arndt V, Stegmaier C, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Meindl A, Heil J, Bartram CR, Schmutzler RK, Thomas GD, Hoover RN, Fletcher O, Gibson LJ, dos Santos Silva I, Peto J, Nickels S, Flesch-Janys D, Anton-Culver H, Ziogas A, Sawyer E, Tomlinson I, Kerin M, Miller N, Schmidt MK, Broeks A, Van 't Veer LJ, Tollenaar RA, Pharoah PD, Dunning AM, Pooley KA, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Jakubowska A, Lubinski J, Jaworska K, Durda K, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Kraft P, Lindstrom S, Chen X, Beesley J, Hamann U, Harth V, Justenhoven C; GENICA Network, Winqvist R, Pylkäs K, Jukkola-Vuorinen A, Grip M, Hooning M, Hollestelle A, Oldenburg RA, Tilanus-Linthorst M, Khusnutdinova E, Bermisheva M, Prokofieva D, Farahtdinova A, Olson JE, Wang X, Humphreys MK, Wang Q, Chenevix-Trench G; kConFab Investigators; AOCS Group, Easton DF.

Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2222-31. doi: 10.1158/1055-9965.EPI-11-0569. Epub 2011 Jul 27.

27.

Gender and binegativity: men's and women's attitudes toward male and female bisexuals.

Yost MR, Thomas GD.

Arch Sex Behav. 2012 Jun;41(3):691-702. doi: 10.1007/s10508-011-9767-8. Epub 2011 May 18.

PMID:
21597943
28.

Extreme values of maternal serum analytes in second trimester screening: looking beyond trisomy and NTD's.

McPherson E, Thomas GD, Manlick C, Zaleski CA, Reynolds KK, Rasmussen K, Giampietro PF, Wiley C, Mascola M.

J Genet Couns. 2011 Aug;20(4):396-403. doi: 10.1007/s10897-011-9364-y. Epub 2011 Apr 20.

PMID:
21505920
29.

Neural control of the circulation.

Thomas GD.

Adv Physiol Educ. 2011 Mar;35(1):28-32. doi: 10.1152/advan.00114.2010. Review.

30.

Functional sympatholysis is impaired in hypertensive humans.

Vongpatanasin W, Wang Z, Arbique D, Arbique G, Adams-Huet B, Mitchell JH, Victor RG, Thomas GD.

J Physiol. 2011 Mar 1;589(Pt 5):1209-20. doi: 10.1113/jphysiol.2010.203026. Epub 2011 Jan 4.

31.

Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2.

Ramesh S, Morrell CN, Tarango C, Thomas GD, Yuhanna IS, Girardi G, Herz J, Urbanus RT, de Groot PG, Thorpe PE, Salmon JE, Shaul PW, Mineo C.

J Clin Invest. 2011 Jan;121(1):120-31. doi: 10.1172/JCI39828. Epub 2010 Dec 1.

32.

Ready, set, flow! But how does the flow know where to go?

Thomas GD.

J Physiol. 2010 Oct 1;588(Pt 19):3633-4. doi: 10.1113/jphysiol.2010.197129. No abstract available.

33.

Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.

Chambliss KL, Wu Q, Oltmann S, Konaniah ES, Umetani M, Korach KS, Thomas GD, Mineo C, Yuhanna IS, Kim SH, Madak-Erdogan Z, Maggi A, Dineen SP, Roland CL, Hui DY, Brekken RA, Katzenellenbogen JA, Katzenellenbogen BS, Shaul PW.

J Clin Invest. 2010 Jul;120(7):2319-30. doi: 10.1172/JCI38291. Epub 2010 Jun 23.

34.

Performance of common genetic variants in breast-cancer risk models.

Wacholder S, Hartge P, Prentice R, Garcia-Closas M, Feigelson HS, Diver WR, Thun MJ, Cox DG, Hankinson SE, Kraft P, Rosner B, Berg CD, Brinton LA, Lissowska J, Sherman ME, Chlebowski R, Kooperberg C, Jackson RD, Buckman DW, Hui P, Pfeiffer R, Jacobs KB, Thomas GD, Hoover RN, Gail MH, Chanock SJ, Hunter DJ.

N Engl J Med. 2010 Mar 18;362(11):986-93. doi: 10.1056/NEJMoa0907727. Erratum in: N Engl J Med. 2010 Dec 2;363(23):2272.

35.

Adenovirus-mediated leptin expression normalises hypertension associated with diet-induced obesity.

Zhang W, Telemaque S, Augustyniak RA, Anderson P, Thomas GD, An J, Wang Z, Newgard CB, Victor RG.

J Neuroendocrinol. 2010 Mar;22(3):175-80. doi: 10.1111/j.1365-2826.2010.01953.x. Epub 2010 Jan 5.

PMID:
20059648
36.

A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies.

Jacobs KB, Yeager M, Wacholder S, Craig D, Kraft P, Hunter DJ, Paschal J, Manolio TA, Tucker M, Hoover RN, Thomas GD, Chanock SJ, Chatterjee N.

Nat Genet. 2009 Nov;41(11):1253-7. doi: 10.1038/ng.455. Epub 2009 Oct 4.

37.

Inhibition of nitric oxide synthase evokes central sympatho-excitation in healthy humans.

Young CN, Fisher JP, Gallagher KM, Whaley-Connell A, Chaudhary K, Victor RG, Thomas GD, Fadel PJ.

J Physiol. 2009 Oct 15;587(Pt 20):4977-86. doi: 10.1113/jphysiol.2009.177204. Epub 2009 Sep 1.

38.

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy.

Lai Y, Thomas GD, Yue Y, Yang HT, Li D, Long C, Judge L, Bostick B, Chamberlain JS, Terjung RL, Duan D.

J Clin Invest. 2009 Mar;119(3):624-35. doi: 10.1172/JCI36612. Epub 2009 Feb 23.

39.

Using public relations strategies to prompt populations at risk to seek health information: the Hanford Community Health Project.

Thomas GD, Smith SM, Turcotte JA.

Health Promot Pract. 2009 Jan;10(1):92-101. doi: 10.1177/1524839907307676. Epub 2008 Mar 19.

PMID:
18353906
40.

Low concentrations of sphingosylphosphorylcholine enhance pulmonary artery vasoreactivity: the role of protein kinase C delta and Ca2+ entry.

Snetkov VA, Thomas GD, Teague B, Leach RM, Shaifta Y, Knock GA, Aaronson PI, Ward JP.

Hypertension. 2008 Feb;51(2):239-45. Epub 2007 Dec 24.

41.

Merkel cell carcinoma in a male breast: a case report.

Alzaraa A, Thomas GD, Vodovnik A, Modgill VK.

Breast J. 2007 Sep-Oct;13(5):517-9.

PMID:
17760677
42.

C-reactive protein causes downregulation of vascular angiotensin subtype 2 receptors and systolic hypertension in mice.

Vongpatanasin W, Thomas GD, Schwartz R, Cassis LA, Osborne-Lawrence S, Hahner L, Gibson LL, Black S, Samols D, Shaul PW.

Circulation. 2007 Feb 27;115(8):1020-8. Epub 2007 Feb 5.

PMID:
17283257
43.

Reactive oxygen species impair sympathetic vasoregulation in skeletal muscle in angiotensin II-dependent hypertension.

Zhao W, Swanson SA, Ye J, Li X, Shelton JM, Zhang W, Thomas GD.

Hypertension. 2006 Oct;48(4):637-43. Epub 2006 Aug 28.

PMID:
16940212
44.

Smooth muscle-specific dystrophin expression improves aberrant vasoregulation in mdx mice.

Ito K, Kimura S, Ozasa S, Matsukura M, Ikezawa M, Yoshioka K, Ueno H, Suzuki M, Araki K, Yamamura K, Miwa T, Dickson G, Thomas GD, Miike T.

Hum Mol Genet. 2006 Jul 15;15(14):2266-75. Epub 2006 Jun 15.

PMID:
16777842
45.

Mechanisms of the prostaglandin F2alpha-induced rise in [Ca2+]i in rat intrapulmonary arteries.

Snetkov VA, Knock GA, Baxter L, Thomas GD, Ward JP, Aaronson PI.

J Physiol. 2006 Feb 15;571(Pt 1):147-63. Epub 2005 Dec 15.

46.

FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase.

Mineo C, Gormley AK, Yuhanna IS, Osborne-Lawrence S, Gibson LL, Hahner L, Shohet RV, Black S, Salmon JE, Samols D, Karp DR, Thomas GD, Shaul PW.

Circ Res. 2005 Nov 25;97(11):1124-31. Epub 2005 Nov 3.

PMID:
16269657
47.

Nitric oxide pathway as new drug targets for refractory hypertension.

Augustyniak RA, Thomas GD, Victor RG, Zhang W.

Curr Pharm Des. 2005;11(25):3307-15. Review.

PMID:
16250858
48.

Flow-mediated dilation and biological variability.

Thomas GD.

J Appl Physiol (1985). 2005 Oct;99(4):1626. No abstract available.

49.

Skin blood flow influences near-infrared spectroscopy-derived measurements of tissue oxygenation during heat stress.

Davis SL, Fadel PJ, Cui J, Thomas GD, Crandall CG.

J Appl Physiol (1985). 2006 Jan;100(1):221-4. Epub 2005 Sep 8.

50.

Modulation of PGF2alpha- and hypoxia-induced contraction of rat intrapulmonary artery by p38 MAPK inhibition: a nitric oxide-dependent mechanism.

Knock GA, De Silva AS, Snetkov VA, Siow R, Thomas GD, Shiraishi M, Walsh MP, Ward JP, Aaronson PI.

Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L1039-48. Epub 2005 Jul 29.

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