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Items: 1 to 50 of 233

1.

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A.

Rivero-Ríos P, Romo-Lozano M, Madero-Pérez J, Thomas AP, Biosa A, Greggio E, Hilfiker S.

J Biol Chem. 2019 Feb 1. pii: jbc.RA118.005008. doi: 10.1074/jbc.RA118.005008. [Epub ahead of print]

2.

Cancer-mitochondria-targeted photodynamic therapy with supramolecular assembly of HA and a water soluble NIR cyanine dye.

Thomas AP, Palanikumar L, Jeena MT, Kim K, Ryu JH.

Chem Sci. 2017 Dec 1;8(12):8351-8356. doi: 10.1039/c7sc03169f. Epub 2017 Oct 13.

3.

Response to Drs. Lahiri and Lyden.

Qureshi AI, Ishfaq MF, Rahman HA, Thomas AP.

J Stroke Cerebrovasc Dis. 2017 Sep;26(9):2042. doi: 10.1016/j.jstrokecerebrovasdis.2016.10.032. Epub 2017 Jul 12. No abstract available.

PMID:
28711362
4.

Development of diabetes does not alter behavioral and molecular circadian rhythms in a transgenic rat model of type 2 diabetes mellitus.

Qian J, Thomas AP, Schroeder AM, Rakshit K, Colwell CS, Matveyenko AV.

Am J Physiol Endocrinol Metab. 2017 Aug 1;313(2):E213-E221. doi: 10.1152/ajpendo.00406.2016. Epub 2017 May 2.

5.

Syntheses of Bipyricorroles and Their Meso-Meso Coupled Dimers.

Adinarayana B, Thomas AP, Satha P, Srinivasan A.

Org Lett. 2017 Apr 21;19(8):1986-1989. doi: 10.1021/acs.orglett.7b00513. Epub 2017 Apr 3.

PMID:
28368608
6.

InsP3 Signaling in Apicomplexan Parasites.

Garcia CRS, Alves E, Pereira PHS, Bartlett PJ, Thomas AP, Mikoshiba K, Plattner H, Sibley LD.

Curr Top Med Chem. 2017;17(19):2158-2165. doi: 10.2174/1568026617666170130121042. Review.

7.

Carbatriphyrin(3.1.1)-A Distinct Coordination Approach of BIII to Generate Organoborane and Weak C-H⋅⋅⋅B Interactions.

Adinarayana B, Thomas AP, Yadav P, Mukundam V, Srinivasan A.

Chemistry. 2017 Mar 2;23(13):2993-2997. doi: 10.1002/chem.201605332. Epub 2017 Feb 14.

PMID:
28106933
8.

Checklist of the earthworms (Oligochaeta) of Kerala, a constituent of Western Ghats biodiversity hotspot, India.

Narayanan SP, Sathrumithra S, Christopher G, Thomas AP, Julka JM.

Zootaxa. 2016 Nov 15;4193(1):zootaxa.4193.1.5. doi: 10.11646/zootaxa.4193.1.5.

PMID:
27988705
9.

Administration of Melatonin and Metformin Prevents Deleterious Effects of Circadian Disruption and Obesity in Male Rats.

Thomas AP, Hoang J, Vongbunyong K, Nguyen A, Rakshit K, Matveyenko AV.

Endocrinology. 2016 Dec;157(12):4720-4731. Epub 2016 Sep 21.

10.

Hemicraniectomy versus Conservative Treatment in Large Hemispheric Ischemic Stroke Patients: A Meta-analysis of Randomized Controlled Trials.

Qureshi AI, Ishfaq MF, Rahman HA, Thomas AP.

J Stroke Cerebrovasc Dis. 2016 Sep;25(9):2209-14. doi: 10.1016/j.jstrokecerebrovasdis.2016.03.053. Epub 2016 Jun 15.

PMID:
27318651
11.

Endovascular Treatment versus Best Medical Treatment in Patients with Acute Ischemic Stroke: A Meta-Analysis of Randomized Controlled Trials.

Qureshi AI, Ishfaq MF, Rahman HA, Thomas AP.

AJNR Am J Neuroradiol. 2016 Jun;37(6):1068-73. doi: 10.3174/ajnr.A4775. Epub 2016 Apr 21. Review.

12.

Bipyricorrole: A Corrole Homologue with a Monoanionic Core as a Fluorescence Zn(II) Sensor.

Adinarayana B, Thomas AP, Yadav P, Kumar A, Srinivasan A.

Angew Chem Int Ed Engl. 2016 Jan 18;55(3):969-73. doi: 10.1002/anie.201508829. Epub 2015 Dec 2.

PMID:
26630076
13.

A 6,11,16-Triarylbiphenylcorrole with an adj-CCNN Core: Stabilization of an Organocopper(III) Complex.

Adinarayana B, Thomas AP, Suresh CH, Srinivasan A.

Angew Chem Int Ed Engl. 2015 Sep 1;54(36):10478-82. doi: 10.1002/anie.201503347. Epub 2015 Jul 15.

PMID:
26211906
14.

Noncovalent Surface Locking of Mesoporous Silica Nanoparticles for Exceptionally High Hydrophobic Drug Loading and Enhanced Colloidal Stability.

Palanikumar L, Kim HY, Oh JY, Thomas AP, Choi ES, Jeena MT, Joo SH, Ryu JH.

Biomacromolecules. 2015 Sep 14;16(9):2701-14. doi: 10.1021/acs.biomac.5b00589. Epub 2015 Jul 31.

PMID:
26200587
15.

Differential Regulation of Multiple Steps in Inositol 1,4,5-Trisphosphate Signaling by Protein Kinase C Shapes Hormone-stimulated Ca2+ Oscillations.

Bartlett PJ, Metzger W, Gaspers LD, Thomas AP.

J Biol Chem. 2015 Jul 24;290(30):18519-33. doi: 10.1074/jbc.M115.657767. Epub 2015 Jun 15.

16.

Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1.

Lee C, Park HK, Jeong H, Lim J, Lee AJ, Cheon KY, Kim CS, Thomas AP, Bae B, Kim ND, Kim SH, Suh PG, Ryu JH, Kang BH.

J Am Chem Soc. 2015 Apr 8;137(13):4358-67. doi: 10.1021/ja511893n. Epub 2015 Mar 30.

PMID:
25785725
17.

Activation of Melatonin Signaling Promotes β-Cell Survival and Function.

Costes S, Boss M, Thomas AP, Matveyenko AV.

Mol Endocrinol. 2015 May;29(5):682-92. doi: 10.1210/me.2014-1293. Epub 2015 Feb 19.

18.

Hormone-induced calcium oscillations depend on cross-coupling with inositol 1,4,5-trisphosphate oscillations.

Gaspers LD, Bartlett PJ, Politi A, Burnett P, Metzger W, Johnston J, Joseph SK, Höfer T, Thomas AP.

Cell Rep. 2014 Nov 20;9(4):1209-18. doi: 10.1016/j.celrep.2014.10.033. Epub 2014 Nov 13.

19.

A diet containing a nonfat dry milk matrix significantly alters systemic oxylipins and the endocannabinoid 2-arachidonoylglycerol (2-AG) in diet-induced obese mice.

Dunn TN, Keenan AH, Thomas AP, Newman JW, Adams SH.

Nutr Metab (Lond). 2014 May 30;11:24. doi: 10.1186/1743-7075-11-24. eCollection 2014.

20.

Reliable encoding of stimulus intensities within random sequences of intracellular Ca2+ spikes.

Thurley K, Tovey SC, Moenke G, Prince VL, Meena A, Thomas AP, Skupin A, Taylor CW, Falcke M.

Sci Signal. 2014 Jun 24;7(331):ra59. doi: 10.1126/scisignal.2005237.

21.

Photoenolization via excited state double proton transfer induces "turn on" fluorescence in diformyl diaryl dipyrromethane.

Sreedevi KC, Thomas AP, Aparna KH, Pradhan R, Reddy ML, Lourderaj U, Srinivasan A.

Chem Commun (Camb). 2014 Aug 14;50(63):8667-9. doi: 10.1039/c4cc03668a. Epub 2014 Jun 24.

PMID:
24958598
22.

Calcium-dependent regulation of glucose homeostasis in the liver.

Bartlett PJ, Gaspers LD, Pierobon N, Thomas AP.

Cell Calcium. 2014 Jun;55(6):306-16. doi: 10.1016/j.ceca.2014.02.007. Epub 2014 Feb 17. Review.

PMID:
24630174
23.

Melanocortin 1 receptor (MC1R) gene sequence variation and melanism in the gray (Sciurus carolinensis), fox (Sciurus niger), and red (Sciurus vulgaris) squirrel.

McRobie HR, King LM, Fanutti C, Coussons PJ, Moncrief ND, Thomas AP.

J Hered. 2014 May-Jun;105(3):423-8. doi: 10.1093/jhered/esu006. Epub 2014 Feb 17.

PMID:
24534267
24.

Does disruption of circadian rhythms contribute to beta-cell failure in type 2 diabetes?

Rakshit K, Thomas AP, Matveyenko AV.

Curr Diab Rep. 2014 Apr;14(4):474. doi: 10.1007/s11892-014-0474-4. Review.

25.

Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults.

Piccolo BD, Dolnikowski G, Seyoum E, Thomas AP, Gertz ER, Souza EC, Woodhouse LR, Newman JW, Keim NL, Adams SH, Van Loan MD.

Nutrients. 2013 Aug 26;5(9):3352-66. doi: 10.3390/nu5093352.

26.

Survival of multi-drug resistant enteropathogenic Escherichia coli and Salmonella paratyphi in Vembanadu lake as a function of saltwater barrier along southwest coast of India.

Chandran A, Suson PS, Thomas AP, Hatha M, Mazumder A.

J Water Health. 2013 Jun;11(2):324-32. doi: 10.2166/wh.2013.221.

PMID:
23708579
27.

Structured variable selection with q-values.

Garcia TP, Müller S, Carroll RJ, Dunn TN, Thomas AP, Adams SH, Pillai SD, Walzem RL.

Biostatistics. 2013 Sep;14(4):695-707. doi: 10.1093/biostatistics/kxt012. Epub 2013 Apr 10.

28.

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.

Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, Karpe F, Humphreys S, Bedinger DH, Dunn TN, Thomas AP, Oort PJ, Kieffer DA, Amin R, Bettaieb A, Haj FG, Permana P, Anthony TG, Adams SH.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1175-87. doi: 10.1152/ajpendo.00630.2012. Epub 2013 Mar 19.

29.

A dairy-based high calcium diet improves glucose homeostasis and reduces steatosis in the context of preexisting obesity.

Thomas AP, Dunn TN, Drayton JB, Oort PJ, Adams SH.

Obesity (Silver Spring). 2013 Mar;21(3):E229-35. doi: 10.1002/oby.20039.

30.

Acidocalcisomes of Trypanosoma brucei have an inositol 1,4,5-trisphosphate receptor that is required for growth and infectivity.

Huang G, Bartlett PJ, Thomas AP, Moreno SN, Docampo R.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1887-92. doi: 10.1073/pnas.1216955110. Epub 2013 Jan 14.

31.

Purkinje cell dysfunction and delayed death in plasma membrane calcium ATPase 2-heterozygous mice.

Fakira AK, Gaspers LD, Thomas AP, Li H, Jain MR, Elkabes S.

Mol Cell Neurosci. 2012 Aug;51(1-2):22-31. doi: 10.1016/j.mcn.2012.07.001. Epub 2012 Jul 10.

32.

Protein-ligand crystal structures can guide the design of selective inhibitors of the FGFR tyrosine kinase.

Norman RA, Schott AK, Andrews DM, Breed J, Foote KM, Garner AP, Ogg D, Orme JP, Pink JH, Roberts K, Rudge DA, Thomas AP, Leach AG.

J Med Chem. 2012 Jun 14;55(11):5003-12. doi: 10.1021/jm3004043. Epub 2012 May 21.

PMID:
22612866
33.

Meso-tetrakis(p-sulfonatophenyl)N-confused porphyrin tetrasodium salt: a potential sensitizer for photodynamic therapy.

Thomas AP, Saneesh Babu PS, Asha Nair S, Ramakrishnan S, Ramaiah D, Chandrashekar TK, Srinivasan A, Radhakrishna Pillai M.

J Med Chem. 2012 Jun 14;55(11):5110-20. doi: 10.1021/jm300009q. Epub 2012 Jun 4.

PMID:
22582931
34.

Calcium-dependent physiologic and pathologic stimulus-metabolic response coupling in hepatocytes.

Gaspers LD, Mémin E, Thomas AP.

Cell Calcium. 2012 Jul;52(1):93-102. doi: 10.1016/j.ceca.2012.04.009. Epub 2012 May 6. Review.

35.

4,4,9,9-Tetraphenyl pyrroloindolizine: a structural analogue of calix[2]pyrrole.

Sreedevi KC, Thomas AP, Ramakrishnan S, Salini PS, Holaday MG, Reddy ML, Srinivasan A.

Org Biomol Chem. 2012 May 14;10(18):3600-5. doi: 10.1039/c2ob25228g. Epub 2012 Apr 2.

PMID:
22466398
36.

AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family.

Gavine PR, Mooney L, Kilgour E, Thomas AP, Al-Kadhimi K, Beck S, Rooney C, Coleman T, Baker D, Mellor MJ, Brooks AN, Klinowska T.

Cancer Res. 2012 Apr 15;72(8):2045-56. doi: 10.1158/0008-5472.CAN-11-3034. Epub 2012 Feb 27.

37.
38.

Uterine artery embolization immediately preceding laparoscopic myomectomy.

Goldman KN, Hirshfeld-Cytron JE, Pavone ME, Thomas AP, Vogelzang RL, Milad MP.

Int J Gynaecol Obstet. 2012 Feb;116(2):105-8. doi: 10.1016/j.ijgo.2011.08.022. Epub 2011 Nov 17.

39.

The role of melatonin in parasite biology.

Bagnaresi P, Nakabashi M, Thomas AP, Reiter RJ, Garcia CR.

Mol Biochem Parasitol. 2012 Jan;181(1):1-6. doi: 10.1016/j.molbiopara.2011.09.010. Epub 2011 Oct 1. Review.

PMID:
21982826
40.

Accumulation of mercury and other heavy metals in edible fishes of Cochin backwaters, Southwest India.

Mohan M, Deepa M, Ramasamy EV, Thomas AP.

Environ Monit Assess. 2012 Jul;184(7):4233-45. doi: 10.1007/s10661-011-2258-5. Epub 2011 Aug 6.

PMID:
21822576
41.

Bromoenol lactone inhibits voltage-gated Ca2+ and transient receptor potential canonical channels.

Chakraborty S, Berwick ZC, Bartlett PJ, Kumar S, Thomas AP, Sturek M, Tune JD, Obukhov AG.

J Pharmacol Exp Ther. 2011 Nov;339(2):329-40. doi: 10.1124/jpet.111.183673. Epub 2011 Jul 27.

42.

Potential public health significance of faecal contamination and multidrug-resistant Escherichia coli and Salmonella serotypes in a lake in India.

Abhirosh C, Sherin V, Thomas AP, Hatha AA, Mazumder A.

Public Health. 2011 Jun;125(6):377-9. doi: 10.1016/j.puhe.2011.03.015. Epub 2011 May 26.

PMID:
21620427
43.

Calix[2]-m-benzo[4]phyrin with aggregation-induced enhanced-emission characteristics: application as a HgII chemosensor.

Salini PS, Thomas AP, Sabarinathan R, Ramakrishnan S, Sreedevi KC, Reddy ML, Srinivasan A.

Chemistry. 2011 Jun 6;17(24):6598-601. doi: 10.1002/chem.201100046. Epub 2011 Apr 28. No abstract available.

PMID:
21538610
44.

Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women.

Thomas AP, Dunn TN, Oort PJ, Grino M, Adams SH.

J Nutr. 2011 Jun;141(6):1172-80. doi: 10.3945/jn.110.127068. Epub 2011 Apr 20.

PMID:
21508205
45.

Avoidance of a generalist entomopathogenic fungus by the ladybird, Coccinella septempunctata.

Ormond EL, Thomas AP, Pell JK, Freeman SN, Roy HE.

FEMS Microbiol Ecol. 2011 Aug;77(2):229-37. doi: 10.1111/j.1574-6941.2011.01100.x. Epub 2011 May 6.

46.

Comparison of metal accumulation in the selected fishes from two sites of Vembanad backwaters, Kerala, India.

Mahesh M, Deepa M, Thomas AP.

J Environ Sci Eng. 2010 Jul;52(3):193-8.

PMID:
21391390
47.

Melatonin and IP3-induced Ca2+ release from intracellular stores in the malaria parasite Plasmodium falciparum within infected red blood cells.

Alves E, Bartlett PJ, Garcia CR, Thomas AP.

J Biol Chem. 2011 Feb 18;286(7):5905-12. doi: 10.1074/jbc.M110.188474. Epub 2010 Dec 13.

48.

A fungal pathogen in time and space: the population dynamics of Beauveria bassiana in a conifer forest.

Ormond EL, Thomas AP, Pugh PJ, Pell JK, Roy HE.

FEMS Microbiol Ecol. 2010 Oct;74(1):146-54. doi: 10.1111/j.1574-6941.2010.00939.x. Epub 2010 Jul 20.

49.

Calix[n]metallocenyl[m]phyrins (n = 1, 2 and m = 2, 4): aryl vs. alkyl.

Ramakrishnan S, Anju KS, Thomas AP, Suresh E, Srinivasan A.

Chem Commun (Camb). 2010 Jul 14;46(26):4746-8. doi: 10.1039/c001187h. Epub 2010 May 25.

PMID:
20502778
50.

A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction.

Kovalenko OA, Caron MJ, Ulema P, Medrano C, Thomas AP, Kimura M, Bonini MG, Herbig U, Santos JH.

Aging Cell. 2010 Apr;9(2):203-19. doi: 10.1111/j.1474-9726.2010.00551.x.

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